{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T10:59:16Z","timestamp":1753181956239},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"4-5","license":[{"start":{"date-parts":[[1985,2,1]],"date-time":"1985-02-01T00:00:00Z","timestamp":476064000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Graefe's Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[1985,2]]},"DOI":"10.1007\/bf02133690","type":"journal-article","created":{"date-parts":[[2005,9,14]],"date-time":"2005-09-14T20:38:04Z","timestamp":1126730284000},"page":"250-253","source":"Crossref","is-referenced-by-count":6,"title":["Blood-retinal barriers in juvenile diabetics in relation to early clinical manifestations, HLA-DR types, and metabolic control"],"prefix":"10.1007","volume":"222","author":[{"given":"Anna","family":"Kernell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johnny","family":"Ludvigsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02133690_CR1","unstructured":"Akerblom H (1980) The definition of remission. Presentation at the 5th Annual Meeting of the International Study Group of Diabetes in Children and Adolescents, Berlin"},{"key":"BF02133690_CR2","unstructured":"Akerblom H (1984) The definition of remission. In: Akerblom H (ed) \u201cThe remission period\u201d, pediatric and adolescent Endocrinology. S. Karger, (in press)"},{"key":"BF02133690_CR3","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0002-9394(14)74846-9","volume":"90","author":"J Barbosa","year":"1980","unstructured":"Barbosa J, Ramsey RC, Knobloch WH, Cantrill HL, Noreen H, King R (1980) Histocomptability frequencies in diabetic retinopathy. Am J Ophthalmol 90: 148\u201353","journal-title":"Am J Ophthalmol"},{"key":"BF02133690_CR4","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/BF01564553","volume":"9","author":"L Barta","year":"1972","unstructured":"Barta L, Brooser G, Molnar M (1972) Diagnostic importance of fluorescein angiography in infantile diabetes. Acta Diabetol Lat 9:290\u201398","journal-title":"Acta Diabetol Lat"},{"key":"BF02133690_CR5","doi-asserted-by":"crossref","first-page":"997","DOI":"10.2337\/diab.26.10.997","volume":"26","author":"B Becker","year":"1977","unstructured":"Becker B, Shier DH, Burgess D, Kilo C, Miller NW (1977) Histocompatibility antigens and diabetic retinopathy. Diabetes 26:997\u201399","journal-title":"Diabetes"},{"key":"BF02133690_CR6","doi-asserted-by":"crossref","first-page":"70","DOI":"10.2337\/diab.31.1.70","volume":"31","author":"HJ Bodansky","year":"1982","unstructured":"Bodansky HJ, Wolf E, Cudworth AG, Dean BM, Ninehaum LJ, Bottazzo GF, Matthews JA, Kurtz AB, Kohner EM (1982) Genetic and immunologic factors in microvascular disease in type I insulin-dependent diabetes. Diabetes 31:70\u201374","journal-title":"Diabetes"},{"key":"BF02133690_CR7","first-page":"233","volume":"166","author":"G Brooser","year":"1975","unstructured":"Brooser G, Barta L, Anda L, Molnar M (1975) Fr\u00fche Diagnose der Micro angiopathie bei kindlicher Diabetes. Klin Monatsbl Augenheilkd 166:233\u201336","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"BF02133690_CR8","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1055\/s-0028-1093961","volume":"5","author":"AH Christiansen","year":"1973","unstructured":"Christiansen AH (1973) Radioimmuno-electrophoresis in the determination of insulin binding to igG methodological studies. Horm Res 5:147\u201354","journal-title":"Horm Res"},{"key":"BF02133690_CR9","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0039-6257(79)90158-9","volume":"23","author":"JG Chunha-Vaz","year":"1979","unstructured":"Chunha-Vaz JG (1979) The blood-ocular barriers. Surv Ophthalmol 23:279\u201395","journal-title":"Surv Ophthalmol"},{"key":"BF02133690_CR10","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1136\/bjo.59.11.649","volume":"59","author":"JG Cunha-Vaz","year":"1975","unstructured":"Cunha-Vaz JG, Faria de Abreu JR, Campos AJ, Figo G (1975) Early breakdown of the blood-retinal barrier in diabetes. Br J Ophthalmol 59:649\u201356","journal-title":"Br J Ophthalmol"},{"key":"BF02133690_CR11","doi-asserted-by":"crossref","first-page":"16","DOI":"10.2337\/diab.28.1.16","volume":"28","author":"JG Cunha-Vaz","year":"1978","unstructured":"Cunha-Vaz JG, Fonseca JR, Abreu JF, Ruas MA (1978) Detection of early retinal changes in diabetes by vitreous fluorophotometry. Diabetes 28:16\u201319","journal-title":"Diabetes"},{"key":"BF02133690_CR12","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1530\/acta.0.0970042","volume":"97","author":"PA Dahlberg","year":"1981","unstructured":"Dahlberg PA, Holmlund G, Karlsson FA, Sawenborg F (1981) HLA-A, -B, -C and DR-antigens in patients with Grave's disease and their correlation with signs and clinical course. Acta Endocrinologica 97:42\u201347","journal-title":"Acta Endocrinologica"},{"key":"BF02133690_CR13","doi-asserted-by":"crossref","first-page":"360","DOI":"10.2337\/diacare.4.3.360","volume":"4","author":"D Daneman","year":"1981","unstructured":"Daneman D, Drash AL, Lobes LA, Becker DJ, Baker LM, Travis LB (1981) Progressive retinopathy with improved control in diabetic dwarfism (Mauriac's syndrome). Diabetes Care 4:360\u201365","journal-title":"Diabetes Care"},{"key":"BF02133690_CR14","first-page":"265","volume":"21","author":"TL Dornan","year":"1981","unstructured":"Dornan TL, Ting A, McPherson K, Plowright C, Mann JI, Turner RC (1981) Poor diabetic control and genetic type (HLA-DRY) are risk factors for retinopathy in insulin-dependent diabetes. Diabetologia 21:265 (Abstract)","journal-title":"Diabetologia"},{"key":"BF02133690_CR15","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/BF01225569","volume":"8","author":"LG Heding","year":"1972","unstructured":"Heding LG (1972) Determination of total serum insulin (IRI) in insulin-treated diabetic patients. Diabetologia 8:260\u201366","journal-title":"Diabetologia"},{"key":"BF02133690_CR16","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/BF01222104","volume":"11","author":"LG Heding","year":"1975","unstructured":"Heding LG (1975) Radioimmunological determination of human C-peptide in serum. Diabetologia 11:541\u2013548","journal-title":"Diabetologia"},{"key":"BF02133690_CR17","doi-asserted-by":"crossref","first-page":"463","DOI":"10.2337\/diab.25.5.463","volume":"25","author":"D Job","year":"1974","unstructured":"Job D, Eschwege E, Guyot Argenton C, Aubry JP, Tchobroutsky G (1974) Effect of multiple daily insulin injections on the course of diabetic retinopathy. Diabetes 25: 463\u201369","journal-title":"Diabetes"},{"key":"BF02133690_CR18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2337\/diab.9.1.1","volume":"9","author":"S Johansson","year":"1960","unstructured":"Johansson S (1960) Retinopathy and nephropathy in diabetes mellitus. Comparison of the effect of two forms of treatment. Diabetes 9:1\u20138","journal-title":"Diabetes"},{"key":"BF02133690_CR19","first-page":"320","volume":"3","author":"A Kernell","year":"1982","unstructured":"Kernell A, Tenland T (1982) Vitreous fluorophotometry \u2014 evaluation of an instrument for the study of diabetic retinopathy. Innov Tech Biol Med 3:320\u201337","journal-title":"Innov Tech Biol Med"},{"key":"BF02133690_CR20","first-page":"291","volume":"21","author":"J Kjaergaard","year":"1981","unstructured":"Kjaergaard J, Orth V (1981) Ocular fluorophotometry in diabetes with adjustments for plasmafree fluorescein. Diabetologia 21:291 (Abstract)","journal-title":"Diabetologia"},{"key":"BF02133690_CR21","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/j.1755-3768.1981.tb08735.x","volume":"59","author":"B Krogsaa","year":"1981","unstructured":"Krogsaa B, Lund-Andersen H, Mensen J, Sestoft L, Larsen J (1981) The blood-retinal barrier permeability in diabetic patients. Acta Ophthalmol 59:689\u2013694","journal-title":"Acta Ophthalmol"},{"key":"BF02133690_CR22","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1001\/archopht.1978.03910050418002","volume":"96","author":"T Krupin","year":"1978","unstructured":"Krupin T, Waltman SR, Oestrich C, Santiago J, Ratzan S, Kilo C, Becker B (1978) Vtreous fluorophotometry in juvenile onset diabetes mellitus. Arch Ophthalmol 96:812\u2013814","journal-title":"Arch Ophthalmol"},{"key":"BF02133690_CR23","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/S0140-6736(77)91541-0","volume":"ii","author":"R Lanoe","year":"1977","unstructured":"Lanoe R, Thibult N, Eschwege E, Soria C, Tchorbroutsky G (1977) Glycosylated hemoglobin concentrations and Clinitest results in insulin-dependent diabetics. Lancet ii: 1156","journal-title":"Lancet"},{"key":"BF02133690_CR24","first-page":"510","volume":"21","author":"P Lawson","year":"1981","unstructured":"Lawson P, White M, Rosentock J, Kohner EM (1981) Failure of continuous subcutaneous insulin infusion as a therapeutic tool in severe forms of diabetic retinopathy. Diabetologia 21:510 (Abstract)","journal-title":"Diabetologia"},{"key":"BF02133690_CR25","unstructured":"Ludvigsson J (1976) Metabolic control in juvenile diabetes mellitus. Link\u00f6ping University Med. Diss No 42, Link\u00f6ping"},{"key":"BF02133690_CR26","doi-asserted-by":"crossref","first-page":"673","DOI":"10.2337\/diab.26.7.673","volume":"26","author":"JI Malone","year":"1977","unstructured":"Malone JI, Van Cader TC, Edwards WC (1977) Diabetic vascular changes in children. Diabetes 26:673\u2013679","journal-title":"Diabetes"},{"key":"BF02133690_CR27","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF00429774","volume":"14","author":"EB Moller","year":"1978","unstructured":"Moller EB, Persson B, Sterky G (1978) HLA phenotypes and diabetic retinopathy. Diabetologia 14:155\u2013158","journal-title":"Diabetologia"},{"key":"BF02133690_CR28","first-page":"II","volume":"20","author":"CC Mota","year":"1981","unstructured":"Mota CC, Abrev JF, Gouveia MO, Cunha-Vaz JG (1981) Plasma levels and protein binding of fluorescein in normal and diabetic patients. Invest Ophthalmol Vis Sci (Suppl) 20:II","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BF02133690_CR29","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1001\/archopht.1982.01030040138025","volume":"100","author":"AG Palenstine","year":"1982","unstructured":"Palenstine AG, Brubaker RF (1982) Plasma binding of fluorescein in normal subjects and in diabetic patients. Arch Ophthalmol 100:1160\u20131161","journal-title":"Arch Ophthalmol"},{"key":"BF02133690_CR30","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2337\/diacare.1.3.168","volume":"1","author":"I Pirart","year":"1978","unstructured":"Pirart I (1978) Diabetes mellitus and its degenerative complications: a prospective study of 4400 patients observed between 1947 and 1973. Diabetes Care: 1:168\u2013188, 252\u2013263","journal-title":"Diabetes Care"},{"key":"BF02133690_CR31","first-page":"13","volume":"18","author":"GI Scherntaner","year":"1980","unstructured":"Scherntaner GI, Heding H, Freyler H, Mayr WR, Tappeiner (1980) Diabetic retinopathy in type I diabetes: analysis of genetic immunological and endocrine factors. Diabetologia 18:13 (Abstract)","journal-title":"Diabetologia"},{"key":"BF02133690_CR32","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF00421230","volume":"15","author":"G Tchobroutsky","year":"1978","unstructured":"Tchobroutsky G (1978) Relation of diabetic control to development of microvascular complications. Diabetologia 15:143\u2013152","journal-title":"Diabetologia"},{"key":"BF02133690_CR33","first-page":"18","volume":"3","author":"E Topper","year":"1979","unstructured":"Topper E, Karp M, Doron M, Laron Z (1979) Glycosylated hemoglobin as index control in insulin-dependent diabetic children and adolescents. Bull Intern Study Group on Diabetes in Children and Adolescents 3:18\u201320","journal-title":"Bull Intern Study Group on Diabetes in Children and Adolescents"},{"key":"BF02133690_CR34","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1001\/archopht.1978.03910050480018","volume":"96","author":"S Waltman","year":"1978","unstructured":"Waltman S, Krupin T, Hanish S, Oestrich C, Becker B (1978a) Alteration of the blood-retinal barrier in experimental diabetes mellitus. Arch Ophthalmol 96: 878\u2013879","journal-title":"Arch Ophthalmol"},{"key":"BF02133690_CR35","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2337\/diab.27.2.85","volume":"27","author":"SR Waltman","year":"1978","unstructured":"Waltman SR, Oestrich C, Krupin T, Hanish S, Ratzan S, Santiago J, Kilo C (1978b) Quantitative vitreous fluorophotometry. A sensitive technique for measuring early breakdown of the blood-retinal barrier in young diabetic patients. Diabetes 27:85\u201387","journal-title":"Diabetes"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02133690.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02133690\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02133690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T15:35:50Z","timestamp":1557848150000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02133690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,2]]},"references-count":35,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[1985,2]]}},"alternative-id":["BF02133690"],"URL":"https:\/\/doi.org\/10.1007\/bf02133690","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,2]]}}}