{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:16:15Z","timestamp":1792199775794,"version":"4.4.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[1990,3,1]],"date-time":"1990-03-01T00:00:00Z","timestamp":636249600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[1990,3]]},"DOI":"10.1007\/bf02205560","type":"journal-article","created":{"date-parts":[[2005,10,6]],"date-time":"2005-10-06T00:37:59Z","timestamp":1128559079000},"page":"123-131","source":"Crossref","is-referenced-by-count":40,"title":["Anti-Ro (SSA)\/La (SSB) antibodies and Sj\u00f6gren's syndrome"],"prefix":"10.1007","volume":"9","author":[{"given":"H. M.","family":"Moutsopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. V.","family":"Zerva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02205560_CR1","doi-asserted-by":"crossref","unstructured":"Harley, J.B. Autoantibodies in Sj\u00f6gren's syndrome. In Sj\u00f6gren's Syndrome. Eds: Talal, N., Moutsopoulos, H.M., Kassan, S.S., Springer-Verlag, 1987, 218\u2013234.","DOI":"10.1007\/978-3-642-50118-0_21"},{"key":"BF02205560_CR2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4049\/jimmunol.102.1.117","volume":"102","author":"G. Clark","year":"1969","unstructured":"Clark, G., Reichlin, M., Tomasi, T. Characterization of a soluble cytoplasmic antigen reactive with sera from patients with systemic lupus erythematosus. J Immunol 1969, 102, 117\u2013122.","journal-title":"J Immunol"},{"key":"BF02205560_CR3","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/art.1780170413","volume":"17","author":"M. Mattioli","year":"1974","unstructured":"Mattioli, M., Reichlin, M. Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Arthritis Rheum 1974, 17, 421\u2013429.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR4","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1172\/JCI108007","volume":"55","author":"M.A. Alspaugh","year":"1975","unstructured":"Alspaugh, M.A., Tan, E.M. Antibodies to cellular antigens in Sj\u00f6gren's syndrome. J Clin Invest 1975, 55, 1067\u20131073.","journal-title":"J Clin Invest"},{"key":"BF02205560_CR5","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1172\/JCI108637","volume":"59","author":"M. Akizuki","year":"1977","unstructured":"Akizuki, M., Powers, R., Holman, H.R. A soluble acidic protein of the cell nucleus which reacts with serum from patients with systemic lupus erythematosus and Sj\u00f6gren's syndrome. J Clin Invest 1977, 59, 796\u2013798.","journal-title":"J Clin Invest"},{"key":"BF02205560_CR6","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1002\/art.1780220719","volume":"22","author":"M. Alspaugh","year":"1979","unstructured":"Alspaugh, M., Maddison, P.J. Resolution of the identity of certain antigen antibody systems in systemic lupus erythematosus and Sj\u00f6gren's syndrome: an interlaboratory collaboration. Arthritis Rheum 1979, 22, 796\u2013798.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR7","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1128\/MCB.1.12.1138","volume":"1","author":"J.P. Hendrick","year":"1981","unstructured":"Hendrick, J.P., Wolin, S.L., Rinke, J., Lerner, M.R., Steitz, J.A. Ro small cytoplasmic ribonucleoproteins are a subclass of La ribunocleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Mol Cell Biol 1981, 1, 1138\u20131149.","journal-title":"Mol Cell Biol"},{"key":"BF02205560_CR8","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1073\/pnas.81.7.1996","volume":"81","author":"S.L. Wolin","year":"1984","unstructured":"Wolin, S.L., Steitz, J.A. The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs. Proc Natl Acad Sci USA 1984, 81, 1996\u20132000.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF02205560_CR9","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1084\/jem.167.5.1560","volume":"167","author":"E. Ben-Chetrit","year":"1988","unstructured":"Ben-Chetrit, E., Chan, E.K.L., Sullivan, K.F., Tan, E.M. A 52 kD protein is a novel component of the SS-A\/Ro antigenic particle. J Exp Med 1988, 167, 1560\u20131571.","journal-title":"J Exp Med"},{"key":"BF02205560_CR10","doi-asserted-by":"crossref","first-page":"3744","DOI":"10.4049\/jimmunol.136.10.3744","volume":"136","author":"E.K.L. Chan","year":"1986","unstructured":"Chan, E.K.L., Francoeur, A., Tan, E.M. Epitopes, structural domains and asymmetry of amino acid residues in SS-B\/La nuclear protein. J Immunol 1986, 136, 3744\u20133749.","journal-title":"J Immunol"},{"key":"BF02205560_CR11","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/art.1780270207","volume":"27","author":"C.E. Hammon","year":"1984","unstructured":"Hammon, C.E., Deng, J., Peebles, C., Tan, E.M. The importance of tissue substrate in the SS-A\/Ro antigen-antibody system. Arthritis Rheum 1984, 27, 166\u2013173.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0092-8674(82)90099-X","volume":"29","author":"J. Rinke","year":"1982","unstructured":"Rinke, J., Steitz, J.A. Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodies. Cell 1982, 29, 149\u2013159.","journal-title":"Cell"},{"key":"BF02205560_CR13","doi-asserted-by":"crossref","first-page":"9479","DOI":"10.1073\/pnas.85.24.9479","volume":"85","author":"S.L. Deutscher","year":"1988","unstructured":"Deutscher, S.L., Harley, J.B., Keene, J.D. Molecular analysis of the 60-kDa human Ro ribunucleoprotein. Proc Natl Acad Sci USA 1988, 85, 9479\u20139483.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF02205560_CR14","doi-asserted-by":"crossref","first-page":"18043","DOI":"10.1016\/S0021-9258(19)81321-2","volume":"263","author":"J.C. Chambers","year":"1988","unstructured":"Chambers, J.C., Kenan, D., Martin, B.J., Keene, J.D. Genomic structure and amino acid sequence domains of the human La autoantigen. J Biol Chem 1988, 263, 18043\u201318051.","journal-title":"J Biol Chem"},{"key":"BF02205560_CR15","doi-asserted-by":"crossref","first-page":"3212","DOI":"10.4049\/jimmunol.140.9.3212","volume":"140","author":"A.D. Sturgess","year":"1988","unstructured":"Sturgess, A.D., Gregory Peterson, M., McNeilage, J., Whittingham, S., Coppel, R.L. Characteristics and epitope mapping of a cloned human autoantigen La. J Immunol 1988, 140, 3212\u20133218.","journal-title":"J Immunol"},{"key":"BF02205560_CR16","doi-asserted-by":"crossref","unstructured":"Provost, T.T., Alexander, E.L., Reichlin, M. The relationship between anti- Ro(SS-A) precipitin antibody positive Sj\u00f6gren's syndrome and anti-Ro(SS-A) pricipitin antibody positive lupus erythematosus. In: Sj\u00f6gren's syndrome. Editors: Talal, N., Moutsopoulos, H.M., Kassan, S.S., Springer-Verlag, 1987, 244\u2013257.","DOI":"10.1007\/978-3-642-50118-0_23"},{"key":"BF02205560_CR17","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/art.1780230107","volume":"23","author":"H.M. Moutsopoulos","year":"1980","unstructured":"Moutsopoulos, H.M., Klippel, J.H., Pavlidis, N., Wolf, R.O., Sweet, J.B., Steinberg, A.D., Chu, F.C., Tarpley, T.T. Correlative histologic and serologic findings of sicca syndrome in patients with systemic lupus erythematosus. Arthritis Rheum 1980, 23, 36\u201340.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR18","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1136\/ard.43.2.285","volume":"43","author":"H.M. Moutsopoulos","year":"1984","unstructured":"Moutsopoulos, H.M., Giotaki, H.J., Maddison, P.J., Mavridis, A.C., Drosos, A.A., Skopouli, F.N. Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intolerance. Ann Rheum Dis 1984, 43, 285\u2013287.","journal-title":"Ann Rheum Dis"},{"key":"BF02205560_CR19","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0896-8411(88)90008-X","volume":"3","author":"F.N. Skopouli","year":"1988","unstructured":"Skopouli, F.N., Andonopoulos, A.P., Moutsopoulos, H.M. Clinical implications of the presence of anti-Ro(SSA) antibodies in patients with rheumatoid arthritis. J Autoimmunity 1988, 3, 381\u2013388.","journal-title":"J Autoimmunity"},{"key":"BF02205560_CR20","first-page":"89","volume":"Suppl. 61","author":"M.N. Manoussakis","year":"1986","unstructured":"Manoussakis, M.N., Tzioufas, A.G., Pange, P.J.E., Moutsopoulos, H.M. Serological profiles in subgroups of patients with Sjogren's syndrome. Scand J Rheumatol 1986, Suppl. 61, 89\u201392.","journal-title":"Scand J Rheumatol"},{"key":"BF02205560_CR21","doi-asserted-by":"crossref","first-page":"155","DOI":"10.7326\/0003-4819-98-2-155","volume":"98","author":"E.L. Alexander","year":"1983","unstructured":"Alexander, E.L., Arnett, F.C., Provost, T.T., Stevens, M.B. Sj\u00f6gren's syndrome: association of anti-Ro(SSA) antibodies with vasculitis, hematologic abnormalities and serologic hyperreactivity. Ann Intern Med 1983, 98, 155\u2013159.","journal-title":"Ann Intern Med"},{"key":"BF02205560_CR22","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1002\/art.1780290907","volume":"29","author":"A.G. Tzioufas","year":"1986","unstructured":"Tzioufas, A.G., Manoussakis, M.N., Costello, R., Silis, M., Papadopoulos, N.M., Moutsopoulos, H.M. Cryoglobulinemia in autoimmune rheumatic disease. Arthritis Rheum 1986, 29, 1098\u20131104.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR23","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0896-8411(89)90161-3","volume":"2","author":"W. St. Clair","year":"1989","unstructured":"St. Clair, W., Talal, N., Moutsopoulos, H.M., Zerva, L., Keene, J.D., Pisetsky, D.S. Epitope-specificity of anti-La antibodies from patients with Sj\u00f6gren's syndrome. J Autoimmunity 1989, 2, 335\u2013344.","journal-title":"J Autoimmunity"},{"key":"BF02205560_CR24","first-page":"147A","volume":"8","author":"M.N. Manoussakis","year":"1989","unstructured":"Manoussakis, M.N., Zerva, L.V., Siouna-Fatourou, C.G., Katsikis, P.D., Germanidis, G., Mavridis, A., Moutsopoulos, H.M.M. Sj\u00f6gren's syndrome: immunological parameters in saliva. Clin Rheumatol 1989, 8, 147A.","journal-title":"Clin Rheumatol"},{"key":"BF02205560_CR25","doi-asserted-by":"crossref","unstructured":"Horsfall, A.C., Rose, L.M., Maini, R.N. Autoantibody synthesis in salivary glands of Sj\u00f6gren's syndrome patients. J Autoimmunity 1989, in press.","DOI":"10.1016\/0896-8411(89)90189-3"},{"key":"BF02205560_CR26","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1056\/NEJM197910043011405","volume":"301","author":"H.M. Moutsopoulos","year":"1979","unstructured":"Moutsopoulos, H.M., Mann, D.L., Johnson, A.H., Chused, T.M. Genetic differences between primary and secondary sicca syndrome. N Engl J Med 1979, 301, 761\u2013763.","journal-title":"N Engl J Med"},{"key":"BF02205560_CR27","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0896-8411(88)90079-0","volume":"1","author":"C.A. Papasteriades","year":"1988","unstructured":"Papasteriades, C.A., Skopouli, F.N., Drosos, A.A., Andonopoulos, A.P., Moutsopoulos, H.M. HLA-alloantigen associations in Greek patients with Sj\u00f6gren's syndrome. J Autoimmunity 1988, 1, 85\u201390.","journal-title":"J Autoimmunity"},{"key":"BF02205560_CR28","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1002\/art.1780271106","volume":"27","author":"R.W. Wilson","year":"1984","unstructured":"Wilson, R.W., Provost, T.T., Bias, W.B., Alexander, E.L., Edlow, D.W., Hochberg, M.C., Stevens, M., Arnett, F.C. Sj\u00f6gren's syndrome: influence of multiple HLA-D region alloantigens on clinical and serologic expression. Arthritis Rheum 1984, 27, 1245\u20131253.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR29","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/art.1780290207","volume":"29","author":"J.B. Harley","year":"1986","unstructured":"Harley, J.B., Alexander, E.L., Bias, W.B., Fox, O.F., Provost, T.T., Reichlin, M., Yamagata, H., Arnett, F.C. Anti-Ro(SSA) and anti-La(SSB) in patients with Sj\u00f6gren's syndrome. Arthritis Rheum 1986, 29, 196\u2013206.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR30","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1126\/science.3458307","volume":"232","author":"T.B. Harley","year":"1986","unstructured":"Harley, T.B., Reichlin, M., Arnett, F.C., Alexander, E.L., Bias, W.B., Provost, T.T. Gene interaction at HLA-DQ enhances autoantibody production in primary Sj\u00f6gren's syndrome. Science 1986, 232, 1145\u20131147.","journal-title":"Science"},{"key":"BF02205560_CR31","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF00541336","volume":"5","author":"C.A. Papasteriades","year":"1985","unstructured":"Papasteriades, C.A., Kappou, I.D., Skopouli, F.N., Baria, M.N., Fostiropoulos, G.A., Moutsopoulos, H.M. Lack of HLA-antigen association in Greek rheumatoid arthritis patients. Rheumatol Intern 1985, 5, 201\u2013203.","journal-title":"Rheumatol Intern"},{"key":"BF02205560_CR32","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1002\/art.1780251014","volume":"25","author":"E. Penner","year":"1982","unstructured":"Penner, E., Reichlin, M. Primary biliary cirrhosis associated with Sj\u00f6gren's syndrome: evidence for circulating and tissue deposited Ro\/anti-Ro immune complexes. Arthritis Rheum 1982, 25, 1250\u20131253.","journal-title":"Arthritis Rheum"},{"key":"BF02205560_CR33","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/art.1780220808","volume":"22","author":"P.J. Maddison","year":"1979","unstructured":"Maddison, P.J., Reichlin, M. Deposition of antibodies to a soluble cytoplasmic antigen in the kidneys of patients with systemic lupus erythematosus. Arthritis Rheum 1979, 22, 858\u2013863.","journal-title":"Arthritis Rheum"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02205560.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02205560\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02205560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T16:03:12Z","timestamp":1706630592000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02205560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,3]]},"references-count":33,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[1990,3]]}},"alternative-id":["BF02205560"],"URL":"https:\/\/doi.org\/10.1007\/bf02205560","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,3]]}}}