{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:08:06Z","timestamp":1788782886037,"version":"build-2803163510"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,11]]},"DOI":"10.1007\/bf02237057","type":"journal-article","created":{"date-parts":[[2005,10,21]],"date-time":"2005-10-21T09:28:44Z","timestamp":1129886924000},"page":"1406-1410","source":"Crossref","is-referenced-by-count":31,"title":["Treatment of chronic anal fissure with isosorbide dinitrate"],"prefix":"10.1097","volume":"41","author":[{"given":"Joseph","family":"Lysy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yardena","family":"Israelit-Yatzkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirna","family":"Sestiere-Ittah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Keret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Goldin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"BF02237057_CR1","first-page":"1071","volume-title":"Surgery: scientific principles and practice","year":"1993","unstructured":"Greenfield LJ, Mulholland MW, Oldhamkt KT, Zekenock GB, eds. Surgery: scientific principles and practice. Philadelphia: J. B. Lippincott Company, 1993:1071\u20133."},{"key":"BF02237057_CR2","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/BF02076185","volume":"37","author":"R Farouk","year":"1994","unstructured":"Farouk R, Duthie GS, Macgregor AB, Bartolo DC. Sustained internal sphincter hypertonia in patients with chronic anal fissure. Dis Colon Rectum 1994;37:424\u20139.","journal-title":"Dis Colon Rectum"},{"key":"BF02237057_CR3","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF02554725","volume":"32","author":"B Klosterhalfen","year":"1989","unstructured":"Klosterhalfen B, Vogel P, Rixen H, Mittermayer C. Topography of the inferior rectal artery: a possible cause of chronic, primary anal fissures. Dis Colon Rectum 1989;32:43\u201352.","journal-title":"Dis Colon Rectum"},{"key":"BF02237057_CR4","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1007\/BF02054409","volume":"37","author":"WR Shouten","year":"1994","unstructured":"Shouten WR, Briel JW, Auwerda JJ. Relationship between anal pressure and anodermal blood flow: the vascular pathogenesis of anal fissures. Dis Colon Rectum 1994;37:664\u20139.","journal-title":"Dis Colon Rectum"},{"key":"BF02237057_CR5","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0039-6109(16)46190-6","volume":"73","author":"JW Fleshman","year":"1993","unstructured":"Fleshman JW. Anorectal motor physiology and pathophysiology. Surg Clin North Am 1993;73:245\u201365.","journal-title":"Surg Clin North Am"},{"key":"BF02237057_CR6","first-page":"49","volume":"9","author":"M Vafai","year":"1987","unstructured":"Vafai M, Mann CV. Closed lateral internal anal sphincterotomy as an office procedure for the treatment of anal fissures. Coloproctology 1987;9:49\u201353.","journal-title":"Coloproctology"},{"key":"BF02237057_CR7","first-page":"G7","volume":"264","author":"S Chakder","year":"1993","unstructured":"Chakder S, Rattan S. Release of nitric oxide by activation of nonadrenergic noncholinergic neurons of internal anal sphincter. Am J Physiol 1993;264:G7\u201312.","journal-title":"Am J Physiol"},{"key":"BF02237057_CR8","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/0006-291X(92)91716-4","volume":"185","author":"SJ Chung","year":"1992","unstructured":"Chung SJ, Fung HL. A common enzyme may be responsible for the conversion of organic nitrates to nitric oxide in vascular microsomes. Biochem Biophys Res Commun 1992;185:932\u20137.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF02237057_CR9","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1002\/bjs.1800810949","volume":"81","author":"PB Loder","year":"1994","unstructured":"Loder PB, Kamm MA, Nicholls RJ, Phillips RK. Reversible chemical sphincterotomy by local application of glyceryl trinitrate. Br J Surg 1994;81:1386\u20139.","journal-title":"Br J Surg"},{"key":"BF02237057_CR10","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/BF02148842","volume":"38","author":"SR Gorfine","year":"1995","unstructured":"Gorfine SR. Treatment of benign anal disease with topical nitroglycerin. Dis Colon Rectum 1995;38:453\u20137.","journal-title":"Dis Colon Rectum"},{"key":"BF02237057_CR11","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1002\/bjs.1800830614","volume":"83","author":"SJ Waston","year":"1996","unstructured":"Waston SJ, Kamm MA, Nicholls RJ, Phillips RK. Topical glyceryl trinitrate in the treatment of chronic anal fissure. Br J Surg. 1996;83:771\u20135.","journal-title":"Br J Surg"},{"key":"BF02237057_CR12","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1002\/bjs.1800830615","volume":"83","author":"JN Lund","year":"1996","unstructured":"Lund JN, Armitage NC, Scholefield JH. Use of glyceryl trinitrate ointment in the treatment of anal fissure. Br J Surg. 1996;83:776\u20137.","journal-title":"Br J Surg"},{"key":"BF02237057_CR13","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1136\/gut.39.3.465","volume":"39","author":"W Schouten","year":"1996","unstructured":"Schouten W, Briel J, Boerma MO,et al. Pathophysiological aspects and clinical outcome of intra-anal application of isosorbide-dinitrate in patients with chronic anal fissure. Gut. 1996;39:465\u20139.","journal-title":"Gut."},{"key":"BF02237057_CR14","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/BF02587197","volume":"23","author":"H Abcarian","year":"1980","unstructured":"Abcarian H. Surgical correction of chronic anal fissure: results of lateral internal sphincterotomyvs. fissurectomy-midline sphincterotomy. Dis Colon Rectum 1980;23:31\u20136.","journal-title":"Dis Colon Rectum"},{"key":"BF02237057_CR15","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/BF02609311","volume":"22","author":"M Marby","year":"1979","unstructured":"Marby M, Alexander-Williams J, Buchman P,et al. A randomized controlled trial to compare anal dilatation with lateral subcutaneous sphincterotomy for anal fissure. Dis Colon Rectum 1979;22:308\u201311.","journal-title":"Dis Colon Rectum"}],"container-title":["Diseases of the Colon & Rectum"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00003453-199841110-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T22:01:27Z","timestamp":1617919287000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003453-199841110-00013"}},"subtitle":["Long-term results and dose determination"],"short-title":[],"issued":{"date-parts":[[1998,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1998]]}},"URL":"https:\/\/doi.org\/10.1007\/bf02237057","relation":{},"ISSN":["0012-3706"],"issn-type":[{"value":"0012-3706","type":"print"}],"subject":[],"published":{"date-parts":[[1998,11]]}}}