{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T22:58:28Z","timestamp":1765666708338},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,6]]},"DOI":"10.1007\/bf02238026","type":"journal-article","created":{"date-parts":[[2005,11,14]],"date-time":"2005-11-14T17:03:30Z","timestamp":1131987810000},"page":"851-857","source":"Crossref","is-referenced-by-count":13,"title":["Idiopathic slow-transit constipation is not associated with mutations of the RET proto-oncogene or GDNF"],"prefix":"10.1097","volume":"43","author":[{"given":"Charles H.","family":"Knowles","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon A.","family":"Gayther","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Scott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Ramus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen","family":"Anand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman S.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce A.","family":"Ponder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"BF02238026_CR1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1136\/gut.27.1.41","volume":"27","author":"DM Preston","year":"1986","unstructured":"Preston DM, Lennard-Jones JE. Severe chronic constipation of young women: \u201cIdiopathic slow transit constipation\u201d Gut 1986;27:41\u20138.","journal-title":"Gut"},{"key":"BF02238026_CR2","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1007\/BF01538081","volume":"34","author":"G Devroede","year":"1989","unstructured":"Devroede G, Girard G, Bouchoucha M,et al. Idiopathic constipation by colonic dysfunction. Relationship with personality and anxiety. Dig Dis Sci 1989;34:1428\u201333.","journal-title":"Dig Dis Sci"},{"key":"BF02238026_CR3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0016-5085(85)80128-1","volume":"88","author":"S Krishnamurthy","year":"1985","unstructured":"Krishnamurthy S, Schuffler MD, Rohrmann CA, Pope CE 2d. Severe idiopathic constipation is associated with a distinctive abnormality of the colonic myenteric plexus. Gastroenterology 1985;88:26\u201334.","journal-title":"Gastroenterology"},{"key":"BF02238026_CR4","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/BF02148851","volume":"38","author":"HJ Park","year":"1995","unstructured":"Park HJ, Kamm MA, Abbasi AM, Talbot IC. Immunohistochemical study of the colonic muscle and innervation in idiopathic chronic constipation. Dis Colon Rectum 1995;38:509\u201313.","journal-title":"Dis Colon Rectum"},{"key":"BF02238026_CR5","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1007\/BF02052258","volume":"36","author":"WR Schouten","year":"1993","unstructured":"Schouten WR, ten Kate FJ, de Graaf EJ, Gilberts EC, Simons JL. Visceral neuropathy in slow transit constipation: an immunohistochemical investigation with monoclonal antibodies against neurofilament. Dis Colon Rectum 1993;36:1112\u20137.","journal-title":"Dis Colon Rectum"},{"key":"BF02238026_CR6","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s003840050163","volume":"13","author":"AJ Porter","year":"1998","unstructured":"Porter AJ, Wattchow DA, Hunter A, Costa M. Abnormalities of nerve fibres in the circular muscle of patients with slow transit constipation. Int J Colorectal Dis 1998;13:208\u201316.","journal-title":"Int J Colorectal Dis"},{"key":"BF02238026_CR7","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1007\/BF01537263","volume":"34","author":"S Chaussade","year":"1989","unstructured":"Chaussade S, Khyari A, Roche H,et al. Determination of total and segmental colonic transit time in constipated patients: results in 91 patients with a new simplified method. Dig Dis Sci 1989;34:1168\u201372.","journal-title":"Dig Dis Sci"},{"key":"BF02238026_CR8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1046\/j.1365-2168.1999.00994.x","volume":"86","author":"CH Knowles","year":"1999","unstructured":"Knowles CH, Scott SM, Wellmer AC, Pilot M-A, Williams NS, Anand P. Sensory and autonomic neuropathy in patients with idiopathic slow transit constipation. Br J Surg 1999;86:54\u201360.","journal-title":"Br J Surg"},{"key":"BF02238026_CR9","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/0016-5085(86)90578-0","volume":"91","author":"SH Gottlieb","year":"1986","unstructured":"Gottlieb SH, Schuster MM. Dermatoglyphic (fingerprint) evidence for a congenital syndrome of early onset constipation and abdominal pain. Gastroenterology 1986;91:428\u201332.","journal-title":"Gastroenterology"},{"key":"BF02238026_CR10","first-page":"568","volume":"46","author":"JA Badner","year":"1990","unstructured":"Badner JA, Sieber WK, Garver KL, Chakravati A. A genetic study of Hirschsprung disease. Am J Hum Genet 1990;46:568\u201380.","journal-title":"Am J Hum Genet"},{"key":"BF02238026_CR11","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/ng0893-346","volume":"4","author":"S Lyonnet","year":"1993","unstructured":"Lyonnet S, Bolino A, Pelet A,et al. A gene for Hirschsprung's disease maps to the proximal long arm of chromosome 10. Nat Genet 1993;4:346\u201350.","journal-title":"Nat Genet"},{"key":"BF02238026_CR12","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1093\/hmg\/4.5.821","volume":"4","author":"M Angrist","year":"1995","unstructured":"Angrist M, Bolk S, Thiel B,et al. Mutation of the endothelin receptor B gene in Waardenburg-Hirschsprung disease. Hum Mol Genet 1995;1995;4:2407\u20139.","journal-title":"Hum Mol Genet"},{"key":"BF02238026_CR13","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/ng1196-345","volume":"14","author":"R Salomon","year":"1996","unstructured":"Salomon R, Attie T, Pelet A,et al. Germline mutations of the RET ligand GDNF are not sufficient to cause Hirschsprung's disease. Nat Genet 1996;14:345\u20137.","journal-title":"Nat Genet"},{"key":"BF02238026_CR14","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/0092-8674(94)90016-7","volume":"79","author":"EG Puffenberger","year":"1994","unstructured":"Puffenberger EG, Hosada K, Washington SS,et al. A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung's disease. Cell 1994;79:1257\u201366.","journal-title":"Cell"},{"key":"BF02238026_CR15","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/ng0496-445","volume":"12","author":"RM Hofstra","year":"1996","unstructured":"Hofstra RM, Osinga J, Sindhunata GT,et al. A homozygous mutation in the endothelin-3 gene associated with a combined Waardenburg type 2 and Hirschsprung phenotype. Nat Genet 1996;12:445\u20137.","journal-title":"Nat Genet"},{"key":"BF02238026_CR16","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/ng0298-171","volume":"18","author":"V Pingault","year":"1998","unstructured":"Pingault V, Bondurand N, Kuhlbrodt K,et al. SOX10 mutations in patients with Waardenburg-Hirschsprung disease. Nat Genet 1998;18:171\u20133.","journal-title":"Nat Genet"},{"key":"BF02238026_CR17","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/367378a0","volume":"367","author":"P Edery","year":"1994","unstructured":"Edery P, Lyonnet S, Mulligan LM,et al. Mutations of the RET proto-oncogene in Hirschsprung's. Nature 1994;367:378\u201380.","journal-title":"Nature"},{"key":"BF02238026_CR18","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1093\/hmg\/3.12.2163","volume":"12","author":"LM Mulligan","year":"1994","unstructured":"Mulligan LM, Eng C, Attie T,et al. Diverse phenotypes associated with exon 10 mutations of the RET proto-oncogene. Hum Mol Genet 1994;12:2163\u20137.","journal-title":"Hum Mol Genet"},{"key":"BF02238026_CR19","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1086\/301759","volume":"62","author":"J Amiel","year":"1998","unstructured":"Amiel J, Salomon R, Attie T,et al. Mutations of the RET-GDNF signaling pathway in Ondine's curse letter. Am J Hum Genet 1998;62:715\u20137.","journal-title":"Am J Hum Genet"},{"key":"BF02238026_CR20","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/BF01647654","volume":"7","author":"RC Evans","year":"1992","unstructured":"Evans RC, Kamm MA, Hinton JM, Lennard-Jones JE. The normal range and a simple diagram for recording whole gut transit time. Int J Colorectal Dis 1992;7:15\u20137.","journal-title":"Int J Colorectal Dis"},{"key":"BF02238026_CR21","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1007\/BF01295718","volume":"8","author":"JP Roberts","year":"1993","unstructured":"Roberts JP, Newell MS, Deeks JJ, Waldron DW, Garvie NW, Williams NS. Oral111In DTPA scintigraphic assessment of colonic transit in constipated subjects. Dig Dis Sci 1993;8:1032\u20139.","journal-title":"Dig Dis Sci"},{"key":"BF02238026_CR22","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF01887845","volume":"9","author":"P Mahieu","year":"1984","unstructured":"Mahieu P, Pringot J, Bodart P. Defecography. I. Description of a new procedure and results in normal patients. Gastrointest Radiol 1984;9:247\u201351.","journal-title":"Gastrointest Radiol"},{"key":"BF02238026_CR23","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1002\/bjs.1800811143","volume":"81","author":"JS Jameson","year":"1994","unstructured":"Jameson JS, Chia YW, Kamm MA, Speakman CTM, Chye YH, Henry MM. Effect of age, sex and parity on anorectal function. Br J Surg 1994;81:1689\u201392.","journal-title":"Br J Surg"},{"key":"BF02238026_CR24","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1038\/ng1295-428","volume":"11","author":"SA Gayther","year":"1995","unstructured":"Gayther SA, Warren W, Mazoyer S, Russell PA, Harrington P. Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotypephenotype correlation. Nat Genet 1995;11:428\u201333.","journal-title":"Nat Genet"},{"key":"BF02238026_CR25","first-page":"3025","volume":"9","author":"I Ceccherini","year":"1994","unstructured":"Ceccherini I, Hofstra RM, Yin L,et al. DNA polymorphisms and conditions for SSCP analysis of the 20 exons of the RET proto-oncogene [published correction appears in Oncogene 1995;10:1257]. Oncogene 1994;9:3025\u201329.","journal-title":"Oncogene"},{"key":"BF02238026_CR26","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/ng1196-341","volume":"14","author":"M Angrist","year":"1996","unstructured":"Angrist M, Bolk S, Halushka M, Lapchak PA, Chakravarti A. Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient. Nat Genet 1996;14:341\u20133.","journal-title":"Nat Genet"},{"key":"BF02238026_CR27","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/42722","volume":"387","author":"RD Klein","year":"1997","unstructured":"Klein RD, Sherman D, Ho W-H,et al. A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. Nature 1997;387:717\u201321.","journal-title":"Nature"},{"key":"BF02238026_CR28","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1006\/mcne.1998.0682","volume":"11","author":"J Thompson","year":"1998","unstructured":"Thompson J, Doxakis E, Pinon LGP,et al. GFR\u03b1-4, a new GDNF family receptor. Mol Cell Neurosci 1998;11:117\u201326.","journal-title":"Mol Cell Neurosci"},{"key":"BF02238026_CR29","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1242\/dev.122.1.349","volume":"122","author":"PL Durbec","year":"1996","unstructured":"Durbec PL, Larrson-Blomberg LB, Schuchardt A, Constantini F, Pachnis V. Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development 1996;122:349\u201358.","journal-title":"Development"},{"key":"BF02238026_CR30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0959-4388(97)80127-4","volume":"7","author":"MD Gershon","year":"1997","unstructured":"Gershon MD. Genes and lineages in the formation of the enteric nervous system. Curr Opin Neurobiol 1997;7:101\u20139.","journal-title":"Curr Opin Neurobiol"},{"key":"BF02238026_CR31","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0012-1606(98)80010-9","volume":"198","author":"A Chalazonitis","year":"1998","unstructured":"Chalazonitis A, Rothman TP, Chen J, Vinson A, MacLennan J, Gershon MD. Promotion of the development of enteric neurons and glia by neuropoietic cytokines: interactions with NT3. Dev Biol 1998;198:343\u201365.","journal-title":"Dev Biol"}],"container-title":["Diseases of the Colon & Rectum"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00003453-200043060-00019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T17:19:13Z","timestamp":1626715153000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003453-200043060-00019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,6]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2000]]}},"URL":"https:\/\/doi.org\/10.1007\/bf02238026","relation":{},"ISSN":["0012-3706"],"issn-type":[{"value":"0012-3706","type":"print"}],"subject":[],"published":{"date-parts":[[2000,6]]}}}