{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:10:25Z","timestamp":1786979425862,"version":"build-2736575974"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1997,5,1]],"date-time":"1997-05-01T00:00:00Z","timestamp":862444800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[1997,5]]},"DOI":"10.1007\/bf02238958","type":"journal-article","created":{"date-parts":[[2005,12,8]],"date-time":"2005-12-08T19:47:20Z","timestamp":1134071240000},"page":"243-248","source":"Crossref","is-referenced-by-count":36,"title":["Macrophage-colony stimulating factor (M-CSF) is increased in the synovial-like membrane of the periprosthetic tissues in the aseptic loosening of total hip replacement (THR)"],"prefix":"10.1007","volume":"16","author":[{"given":"J. W.","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. T.","family":"Konttinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Waris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"P\u00e4ti\u00e4l\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Sorsa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Santavirta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02238958_CR1","first-page":"44","volume":"1","author":"WJ Wilson","year":"1990","unstructured":"Wilson WJ. Complication of hip arthroplasty. Curr Opinion Orthop 1990; 1: 44\u201354.","journal-title":"Curr Opinion Orthop"},{"key":"BF02238958_CR2","first-page":"142","volume":"287","author":"KJ Kim","year":"1993","unstructured":"Kim KJ, Rubash HE, Wilson SC, D'Antonio J, McClain EJ. A histologic and biochemical comparison of the interface tissues in cementless and cemented hip prostheses. Clin Orthop 1993; 287: 142\u201352.","journal-title":"Clin Orthop"},{"key":"BF02238958_CR3","doi-asserted-by":"crossref","first-page":"575","DOI":"10.2106\/00004623-198365050-00001","volume":"65","author":"SR Goldring","year":"1983","unstructured":"Goldring SR, Schiller AL, Roelke M, O'Neil CM, Harris WH. The synovial-like membrane at the bone-cement interface in loose total hip replacements and its proposed role in bone lysis. J Bone Joint Surg (Am) 1983; 65: 575\u201384.","journal-title":"J Bone Joint Surg (Am)"},{"key":"BF02238958_CR4","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/art.1780290704","volume":"29","author":"SR Goldring","year":"1986","unstructured":"Goldring SR, Jasty M, Roelke MS, Rourke CM, Bringhurst FR, Harris WH. Formation of a synovial-like membrane at the bonecement interface. Its role in bone resorption and implant loosening after total hip replacement. Arthritis Rheum 1986; 29: 836\u201342.","journal-title":"Arthritis Rheum"},{"key":"BF02238958_CR5","doi-asserted-by":"crossref","first-page":"863","DOI":"10.2106\/00004623-199306000-00007","volume":"75","author":"WA Jiranek","year":"1993","unstructured":"Jiranek WA, Machado M, Jasty M, Jevsevar D, Wolfe HJ, Goldring SR, Goldberg MJ, Harris WH. Production of cytokines around loosened cemented acetabular components. J Bone Joint Surg (Am) 1993; 75: 863\u201377.","journal-title":"J Bone Joint Surg (Am)"},{"key":"BF02238958_CR6","first-page":"255","volume":"14","author":"YT Konttinen","year":"1996","unstructured":"Konttinen YT, Kurvinen H, Takagi M, Michelsson JE, Eklund KK, Nordsletten L, Bu\u00f8 L, Aasen AO, Santavirta S. IL-1 vs collagenase around loose total hip prostheses. Clin Exp Rheumatol 1996; 14: 255\u201362.","journal-title":"Clin Exp Rheumatol"},{"key":"BF02238958_CR7","first-page":"128","volume":"9","author":"JW Xu","year":"1996","unstructured":"Xu JW, Konttinen YT, Waris V, G\u00f3mez-Barrena E, Sorsa T, Santavirta S. Granulocyte-macrophage colony stimulating factor in the aseptic loosening of total hip arthroplasty. J Orthop Rheumatol 1996; 9: 128\u201334.","journal-title":"J Orthop Rheumatol"},{"key":"BF02238958_CR8","first-page":"643","volume":"14","author":"JW Xu","year":"1996","unstructured":"Xu JW, Konttinen YT, Lassus J, Natah S, Ceponis A, Solovieva S, Aspenberg P, Santavirta S. Tumor necrosis factor-alpha (TNF-\u03b1) in loosening of total hip replacement (THR). Clin Exp Rheumatol 1996; 14: 643\u20138.","journal-title":"Clin Exp Rheumatol"},{"key":"BF02238958_CR9","unstructured":"Konttinen YT, Xu JW, P\u00e4ti\u00e4l\u00e4 H, Imai S, Li TF, Goodman SB, Nordsletten L, Santavirta S. Cytokines in aseptic loosening of total hip replacement, a state characterized by a local imbalance and\/or inapproriate expression of cytokines regulating osteoclasts and osteoblasts. Curr Orthop in press."},{"key":"BF02238958_CR10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/00003086-199009000-00032","volume":"258","author":"MB Goldring","year":"1990","unstructured":"Goldring MB, Goldring SR. Basic science and pathology: Skeletal tissue resorption to cytokines. Clin Orthop 1990; 258: 245\u201378.","journal-title":"Clin Orthop"},{"key":"BF02238958_CR11","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.2106\/00004623-199508000-00019","volume":"77","author":"JA Buckwalter","year":"1995","unstructured":"Buckwalter JA, Glmcher MJ, Cooper RR, Recker R. Bone biology. J Bone Joint Surg (Am) 1995; 77: 1256\u201389.","journal-title":"J Bone Joint Surg"},{"key":"BF02238958_CR12","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1002\/jbmr.5650060912","volume":"6","author":"N Takahashi","year":"1991","unstructured":"Takahashi N, Udagawa N, Akatsu T, Tanaka H, Shionome M, Suda T. Role of colony-stimulating factors in osteoclast development. J Bone Miner Res 1991; 6: 977\u201385.","journal-title":"J Bone Miner Res"},{"key":"BF02238958_CR13","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1172\/JCI116179","volume":"91","author":"S Tanaka","year":"1993","unstructured":"Tanaka S, Takahashi N, Udagawa N, Tamura T, Akatsu T, Stanley RE, Kurokawa T, Suda T. Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest 1993; 91: 257\u201363.","journal-title":"J Clin Invest"},{"key":"BF02238958_CR14","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1172\/JCI112087","volume":"76","author":"SG Emerson","year":"1985","unstructured":"Emerson SG, Sieff CA, Wang EA, Wong GG, Clark SC, Nathan DG. Purification of fetal hematopoeitic progenitors and demonstration of recombinant multipotential colony stimulating activity. J Clin Invest 1985; 76: 1286\u201390.","journal-title":"J Clin Invest"},{"key":"BF02238958_CR15","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1073\/pnas.85.10.3445","volume":"85","author":"K Ikebuchi","year":"1988","unstructured":"Ikebuchi K, Clark SC, Ihle JN, Souza LM, Ogawa M. Granulocyte colony stimulating factor enhances interleukin 3 dependent proliferation of multipotential haematopoietic progenitors. Proc Natl Acad Sci USA 1988; 85: 3445\u20139.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF02238958_CR16","first-page":"5624","volume":"48","author":"G Morstyn","year":"1988","unstructured":"Morstyn G, Burgess AW. Hemopoietic growth factors: A review. Cancer Res 1988; 48: 5624\u201337.","journal-title":"Cancer Res"},{"key":"BF02238958_CR17","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/jcb.240210206","volume":"21","author":"ER Stanley","year":"1983","unstructured":"Stanley ER, Guillert LJ, Tushinski RJ, Bartelmez SH. CSF-1: A mononuclear phagocyte lineage-specific hemopoietic growth factor. J Cell Biochem 1983; 21: 151\u20139.","journal-title":"J Cell Biochem"},{"key":"BF02238958_CR18","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1210\/endo-127-5-2592","volume":"127","author":"R Felix","year":"1990","unstructured":"Felix R, Cecchini MG, Fleisch H. Macrophage colony stimulating factor restores in vivo bone resorption in theop\/op osteopetrotic mouse. Endocrinology 1990; 127: 2592\u20134.","journal-title":"Endocrinology"},{"issue":"2 Suppl","key":"BF02238958_CR19","doi-asserted-by":"crossref","first-page":"87S","DOI":"10.1016\/8756-3282(95)00185-G","volume":"17","author":"T Suda","year":"1995","unstructured":"Suda T, Udagawa N, Nakamura I, Miyaura C, Takahashi N. Modulation of osteoclast differentiation by local factors. Bone 1995; 17 (2 Suppl): 87S-91S.","journal-title":"Bone"},{"issue":"Suppl 2","key":"BF02238958_CR20","first-page":"S505","volume":"8","author":"GR Mundy","year":"1993","unstructured":"Mundy GR. Cytokines and growth factors in the regulation of bone remodeling. 1993; 8 (Suppl 2): S505-S510.","journal-title":"Cytokines and growth factors in the regulation of bone remodeling"},{"key":"BF02238958_CR21","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.2106\/00004623-199072080-00015","volume":"72","author":"M Jasty","year":"1990","unstructured":"Jasty M, Maloney WJ, Bragdon CR, Haire T, Harris W. Histomorphological studies of the long-term skeletal responses to well fixed cemented femoral components. J Bone Joint Surg (Am) 1990; 72: 1220\u20139.","journal-title":"J Bone Joint Surg (Am)"},{"key":"BF02238958_CR22","doi-asserted-by":"crossref","first-page":"252","DOI":"10.2106\/00004623-199072020-00014","volume":"72","author":"S Santavirta","year":"1990","unstructured":"Santavirta S, Konttinen YT, Bergroth V, Eskola A, Tallroth K, Lindholm TS. Aggressive granulomatous lesions associated with hip arthroplasty. Immunopathological studies. J Bone Joint Surg (Am) 1990; 72: 252\u20138.","journal-title":"J Bone Joint Surg (Am)"},{"key":"BF02238958_CR23","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1302\/0301-620X.73B1.1991772","volume":"73","author":"S Santavirta","year":"1991","unstructured":"Santavirta S, Konttinen YT, Hoikka V, Eskola A. Immunopathological response to loose cementless acetabular components. J Bone Joint Surg (Br) 1991; 73: 38\u201342.","journal-title":"J Bone Joint Surg (Br)"},{"key":"BF02238958_CR24","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/00003086-199208000-00043","volume":"281","author":"DW Murray","year":"1992","unstructured":"Murray DW, Rushton N. Mediators of bone resorption around implants. Clin Orthop 1992; 281: 295\u2013304.","journal-title":"Clin Orthop"},{"key":"BF02238958_CR25","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/ajcp\/105.5.628","volume":"105","author":"N AL-Saffar","year":"1996","unstructured":"AL-Saffar N, Khwaja H, Kadoya Y, Revell PA. Assessment of the role of GM-CSF in the cellular transformation and the development of erosive lesions around orthopaedic implants. Am J Clin Pathol 1996; 105: 628\u201339.","journal-title":"Am J Clin Pathol"},{"key":"BF02238958_CR26","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3109\/17453678709146361","volume":"58","author":"B Levack","year":"1987","unstructured":"Levack B, Revell PA, Freeman MAR. Presence of macrophages at the bone-cement interface of stable hip arthroplasty components. Acta Orthop Scand 1987; 58: 384\u20137.","journal-title":"Acta Orthop Scand"},{"key":"BF02238958_CR27","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/00003086-199403000-00043","volume":"300","author":"J Chiba","year":"1994","unstructured":"Chiba J, Rubash HE, Kim KJ, Iwaki Y. The characterization of cytokines in the interface tissue obtained from failed cementless total hip arthroplasty with and without femoral osteolysis. Clin Orthop 1994; 300: 304\u201312.","journal-title":"Clin Orthop"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02238958.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02238958\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02238958","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T16:50:57Z","timestamp":1683305457000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02238958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,5]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,5]]}},"alternative-id":["BF02238958"],"URL":"https:\/\/doi.org\/10.1007\/bf02238958","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,5]]}}}