{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:11:12Z","timestamp":1780632672728,"version":"3.54.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1993,10,1]],"date-time":"1993-10-01T00:00:00Z","timestamp":749433600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychopharmacology"],"published-print":{"date-parts":[[1993,10]]},"DOI":"10.1007\/bf02244898","type":"journal-article","created":{"date-parts":[[2005,11,14]],"date-time":"2005-11-14T22:59:52Z","timestamp":1132009192000},"page":"483-489","source":"Crossref","is-referenced-by-count":39,"title":["MAO inhibitors in panic disorder: clinical effects of treatment with brofaromine"],"prefix":"10.1007","volume":"112","author":[{"given":"Irene M.","family":"van Vliet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman G. M.","family":"Westenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan A.","family":"Den Boer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02244898_CR1","volume-title":"DSM-III-R: diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1987","unstructured":"American Psychiatric Association (1987) DSM-III-R: diagnostic and statistical manual of mental disorders, 3rd edn. The American Psychiatric Association, revised. Washington, DC","edition":"3rd edn."},{"issue":"suppl","key":"BF02244898_CR2","first-page":"73","volume":"26","author":"R Amrein","year":"1988","unstructured":"Amrein R, Allen SR, Vrasanic D, Stahl M (1988) Antidepressant drug therapy: associated risk. J Neural Transm [suppl] 26:73\u201386","journal-title":"J Neural Transm"},{"key":"BF02244898_CR3","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1097\/00005053-198710000-00002","volume":"175","author":"TA Aronson","year":"1987","unstructured":"Aronson TA (1987) Is panic disorder a distinct diagnostic entity? J Nerv Ment Dis 175:584\u2013594","journal-title":"J Nerv Ment Dis"},{"key":"BF02244898_CR4","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1177\/070674377902400407","volume":"24","author":"RC Bowen","year":"1979","unstructured":"Bowen RC, Kohout J (1979) The relationship between agoraphobia and primary affective disorders. Can Psychiatr Assoc J 24:317\u2013322","journal-title":"Can Psychiatr Assoc J"},{"key":"BF02244898_CR5","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1001\/archpsyc.1984.01790230015002","volume":"41","author":"A Breier","year":"1984","unstructured":"Breier A, Charney DS, Heninger GR (1984) Major depression in patients with agoraphobia and panic disorder. Arch Gen Psychiatry 41:1129\u20131135","journal-title":"Arch Gen Psychiatry"},{"key":"BF02244898_CR6","first-page":"55","volume":"48","author":"J Buigues","year":"1987","unstructured":"Buigues J, Vallejo J (1987) Therapeutic response to phenelzine in patients with panic disorder and agoraphobia with panic attacks. J Clin Psychiatry 48:55\u201359","journal-title":"J Clin Psychiatry"},{"key":"BF02244898_CR7","doi-asserted-by":"crossref","first-page":"517","DOI":"10.3928\/0048-5713-19900901-08","volume":"9","author":"GB Cassano","year":"1990","unstructured":"Cassano GB, Perugi G, Musetti L (1990) Comorbidity in panic disorder. Psychiatr Ann 9:517\u2013521","journal-title":"Psychiatr Ann"},{"key":"BF02244898_CR8","volume-title":"Anxiety: new research and changing concepts","author":"CR Cloninger","year":"1981","unstructured":"Cloninger CR, Martin RL, Clayton P (1981) A blind follow-up and family study of anxiety neurosis. In: Klein DF, Rabkin J (eds) Anxiety: new research and changing concepts. Raven Press, New York."},{"issue":"suppl","key":"BF02244898_CR9","first-page":"31","volume":"26","author":"M Prada Da","year":"1988","unstructured":"Da Prada M, Zurcher G, Wuttrich I, Haefely WE (1988) The cheese effect and new reversible MAO-A inhibitors. On tyramine, food beverages and moclobemide. J Neural Transm [suppl] 26:31\u201356","journal-title":"J Neural Transm"},{"key":"BF02244898_CR10","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/00004850-198801000-00005","volume":"3","author":"JA Boer Den","year":"1988","unstructured":"Den Boer JA, Westenberg HGM (1988) Effects of a serotonin and noradrenaline uptake inhibitor in panic disorder, a double-blind comparative study with fluvoxamine and maprotiline. Int Clin Psychopharmacol 3:59\u201374","journal-title":"Int Clin Psychopharmacol"},{"key":"BF02244898_CR11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF02245749","volume":"102","author":"JA Boer Den","year":"1990","unstructured":"Den Boer JA, Westenberg HGM (1990) Serotonin function in panic disorder, a double-blind placebo controlled study with fluvoxamine and ritanserin. Psychopharmacology 102:85\u201394","journal-title":"Psychopharmacology"},{"key":"BF02244898_CR12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/00004850-198701000-00002","volume":"2","author":"JA Boer Den","year":"1987","unstructured":"Den Boer JA, Westenberg HGM, Kamerbeek WDJ, Verhoeven WMA, Kahn RS (1987) Effect of serotonin uptake inhibitors in anxiety disorders, a double-blind comparison of clomipramine and fluvoxamine. Int Clin Psychopharmacol 2:21\u201332","journal-title":"Int Clin Psychopharmacol"},{"key":"BF02244898_CR13","first-page":"13","volume":"9","author":"LR Derogatis","year":"1973","unstructured":"Derogatis LR, Lipman RS, Covi L (1973) SCL-90: an outpatient psychiatric rating scale; preliminary report. Psychopharmacol Bull 9:13\u201328","journal-title":"Psychopharmacol Bull"},{"key":"BF02244898_CR14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1600-0447.1986.tb02666.x","volume":"73","author":"L Evans","year":"1986","unstructured":"Evans L, Kenardy J, Schneider, P, Hoey H (1986) Effect of a selective serotonin uptake inhibitor in agoraphobia with panic attacks: a double-blind comparison of zimelidine, imipramine and placebo. Acta Psychiatr Scand 73:49\u201353","journal-title":"Acta Psychiatr Scand"},{"key":"BF02244898_CR15","unstructured":"Garcia-Borreguero D, Lauwer CJ, Krieg JC (1991) Brofaromine in the treatment of panic disorders. Biol Psychiatry 29:266S"},{"key":"BF02244898_CR16","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1017\/S0033291700012319","volume":"19","author":"MG Gelder","year":"1989","unstructured":"Gelder MG (1989) Panic disorder: fact or fiction? Psychol Med 19:277\u2013283","journal-title":"Psychol Med"},{"key":"BF02244898_CR17","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1097\/00004714-198710000-00007","volume":"7","author":"JM Gorman","year":"1987","unstructured":"Gorman JM, Liebowitz MR, Fyer AJ (1987) An open trial of fluoxetine in the treatment of panic attacks. J Clin Psychopharmacol 7:329\u2013332","journal-title":"J Clin Psychopharmacol"},{"key":"BF02244898_CR18","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1177\/026988118700100305","volume":"1","author":"FS Guimaraes","year":"1988","unstructured":"Guimaraes FS, Zuardi, AW, Graeff FG (1988) Effect of chlorimipramine and maprotiline on experimental anxiety in humans. J Psychopharmacol 1:184\u2013192","journal-title":"J Psychopharmacol"},{"key":"BF02244898_CR19","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.2044-8341.1959.tb00467.x","volume":"32","author":"M Hamilton","year":"1959","unstructured":"Hamilton M (1959) The assessment of anxiety states by rating. Br J Med Psychol 32:50\u201355","journal-title":"Br J Med Psychol"},{"key":"BF02244898_CR20","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.2044-8260.1967.tb00530.x","volume":"6","author":"M Hamilton","year":"1967","unstructured":"Hamilton M (1967) Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 6:278\u2013296","journal-title":"Br J Soc Clin Psychol"},{"key":"BF02244898_CR21","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0165-0327(85)90046-1","volume":"8","author":"RS Kahn","year":"1985","unstructured":"Kahn RS, Westenberg HGM (1985)l-5-Hydroxytryptophan in the treatment of anxiety disorders. J Affect Dis 8:197\u2013200","journal-title":"J Affect Dis"},{"key":"BF02244898_CR22","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1192\/bjp.116.533.387","volume":"116","author":"DGW Kelly","year":"1970","unstructured":"Kelly DGW, Frommer E, Mitchell-Heggs N, Sargant W (1970) Treatment of phobic states with antidepressants: a retrospective study of 246 patients. Br J Psychiatry 116:387\u2013398","journal-title":"Br J Psychiatry"},{"key":"BF02244898_CR23","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1176\/ajp.119.5.432","volume":"119","author":"DF Klein","year":"1962","unstructured":"Klein DF, Fink M (1962) Psychiatric reaction patterns to imipramine. Am J Psychiatry 119:432\u2013438","journal-title":"Am J Psychiatry"},{"key":"BF02244898_CR24","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/BF02193476","volume":"5","author":"DF Klein","year":"1964","unstructured":"Klein DF (1964) Delineation of two drug-responsive anxiety syndromes. Psychopharmacologica 5:397\u2013408","journal-title":"Psychopharmacologica"},{"key":"BF02244898_CR25","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1001\/archpsyc.1967.01730190120016","volume":"16","author":"DF Klein","year":"1967","unstructured":"Klein DF (1967) The importance of psychiatric diagnosis in prediction of clinical drug effects. Arch Gen Psychiatry 16:118\u2013126","journal-title":"Arch Gen Psychiatry"},{"issue":"6","key":"BF02244898_CR26","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1001\/jama.1991.03460060074027","volume":"265","author":"GI Klerman","year":"1991","unstructured":"Klerman GI, Weissman MM, Ouellette R et al. (1991) Panic attacks in the community. JAMA 265[6]:742\u2013746","journal-title":"JAMA"},{"key":"BF02244898_CR27","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1176\/ajp.140.7.880","volume":"140","author":"JF Leckman","year":"1983","unstructured":"Leckman JF, Merikangas KR, Pauls DL et al. (1983) Anxiety disorders and depression: contradictions between family study data and DSM-III conventions. Am J Psychiatry 140:880\u2013882","journal-title":"Am J Psychiatry"},{"issue":"suppl 6","key":"BF02244898_CR28","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1192\/S0007125000297481","volume":"155","author":"MR Liebowitz","year":"1989","unstructured":"Liebowitz MR (1989) Antidepressants in panic disorders. Br J Psychiatry 155 [suppl 6]:46\u201352","journal-title":"Br J Psychiatry"},{"key":"BF02244898_CR29","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1001\/archpsyc.1988.01800260037004","volume":"5","author":"MR Liebowitz","year":"1988","unstructured":"Liebowitz MR, Quitkin FM, Stewart JW (1988) Antidepressant specificity in atypical depression. Arch Gen Psychiatry 5:129\u2013137","journal-title":"Arch Gen Psychiatry"},{"key":"BF02244898_CR30","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0165-0327(88)90072-9","volume":"14","author":"W Maier","year":"1986","unstructured":"Maier W, Buller R, Phillips M (1986) The Hamilton anxiety scale: reliability, validity and sensitivity to change in anxiety and depresive disorders. J Affect Dis 14:61\u201368","journal-title":"J Affect Dis"},{"key":"BF02244898_CR31","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0005-7967(79)90041-X","volume":"17","author":"IM Marks","year":"1979","unstructured":"Marks IM, Matthews AM (1979) Brief standard self-rating for phobic patients. Behav Res Ther 17:263\u2013267","journal-title":"Behav Res Ther"},{"key":"BF02244898_CR32","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0005-7967(86)90154-3","volume":"24","author":"M Mavissakalian","year":"1986","unstructured":"Mavissakalian M (1986) The fear questionaire: a validity study. Behav Res Ther 24:83\u201385","journal-title":"Behav Res Ther"},{"issue":"suppl 335","key":"BF02244898_CR33","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-0447.1987.tb07749.x","volume":"76","author":"K Modigh","year":"1987","unstructured":"Modigh K (1987) Antidepressant drugs in anxiety disorders. Acta Psychiatr Scand 76[suppl 335]:57\u201371","journal-title":"Acta Psychiatr Scand"},{"key":"BF02244898_CR34","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","volume":"134","author":"SA Montgomery","year":"1979","unstructured":"Montgomery SA, \u00c5sberg M (1979) A new depression scale designed to be sensitive to change. Br J Psychiatry 134:382\u2013389","journal-title":"Br J Psychiatry"},{"key":"BF02244898_CR35","first-page":"211","volume":"22","author":"A Ozdaglar","year":"1989","unstructured":"Ozdaglar A, Lauwer CJ (1989) Brofaromine (CGP 11305A) in the treatment of panic disorders. Pharmacopsychiatry 22:211\u2013222","journal-title":"Pharmacopsychiatry"},{"key":"BF02244898_CR36","doi-asserted-by":"crossref","unstructured":"Sargant W (1961) Drugs in the treatment of depression. BMJ 225\u2013227","DOI":"10.1136\/bmj.1.5221.225"},{"key":"BF02244898_CR37","doi-asserted-by":"crossref","unstructured":"Sargant W, Dally PJ (1962) Treatment of anxiety states by antidepressant drugs. BMJ 6\u20139","DOI":"10.1136\/bmj.1.5270.6"},{"key":"BF02244898_CR38","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1001\/archpsyc.1980.01780140053006","volume":"37","author":"DV Sheehan","year":"1980","unstructured":"Sheehan DV, Ballenger JC, Jacobson G (1980) Treatment of endogenous anxiety with phobic, hysterical and hypochondric symptoms. Arch Gen Psychiatry 37:51\u201359","journal-title":"Arch Gen Psychiatry"},{"key":"BF02244898_CR39","unstructured":"Sheehan DV, Claycomb JB, Surman OS (1984) Comparison of phenelzine, imipramine, alprazolam and placebo in the treatment of panic attacks and agoraphobia. Presented at the American Psychiatric Association Meeting, Los Angeles"},{"key":"BF02244898_CR40","first-page":"25","volume":"18","author":"L Solyom","year":"1973","unstructured":"Solyom L, Heseltine, GFD, McClure DJ, Solyom C, Ledwidge B, Steinberg G (1973) Behavioural therapy versus drug therapy in the treatment of phobic neurosis. Can Psychiatr Ass J 18:25\u201332","journal-title":"Can Psychiatr Ass J"},{"key":"BF02244898_CR41","first-page":"239","volume":"16","author":"C Solyom","year":"1981","unstructured":"Solyom C, Solyom L, LaPierre Y, Pecknold J, Morton L (1981) Phenelzine and exposure in the treatment of phobias. Biol Psychiatry 16:239\u2013247","journal-title":"Biol Psychiatry"},{"key":"BF02244898_CR42","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/BF00422146","volume":"32","author":"P Tyrer","year":"1973","unstructured":"Tyrer P, Candy J, Kelly D (1973a) A study of the clinical effects of phenelzine and placebo in the treatment of phobic anxiety. Psychopharmacology 32:237\u2013254","journal-title":"Psychopharmacology"},{"key":"BF02244898_CR43","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1017\/S0033291700046419","volume":"3","author":"P Tyrer","year":"1973","unstructured":"Tyrer P, Candy J, Kelly D (1973b) Phenelzine in phobic anxiety: a controlled trial. Psychol Med 3:120\u2013124","journal-title":"Psychol Med"},{"key":"BF02244898_CR44","volume-title":"Handleiding bij de zelf-beoordelingsvragenlijst","author":"HM Ploeg Van der","year":"1981","unstructured":"Van der Ploeg HM, Defares PB, Spielberger CD (1981) \u2018Handleiding bij de zelf-beoordelingsvragenlijst\u2019. Sweets and Zeitlinger, Lisse"},{"key":"BF02244898_CR45","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1093\/oxfordjournals.aje.a114201","volume":"122","author":"MR Korff Von","year":"1985","unstructured":"Von Korff MR, Eaton WW. Keyl PM (1985) The epidemiology of panic attacks and panic disorder: results of three community surveys. Am J Epidemiol 122:970\u2013980","journal-title":"Am J Epidemiol"},{"key":"BF02244898_CR46","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/BF00647833","volume":"324","author":"PC Waldmeier","year":"1983","unstructured":"Waldmeier PC, Baumann PA (1983) A new reversible and selective inhibitor of MAO-A, on biogenic amine levels and metabolism in rat brain. Naunyn-Schiedeberg's Arch Pharmacol 324:20\u201326","journal-title":"Naunyn-Schiedeberg's Arch Pharmacol"},{"key":"BF02244898_CR47","unstructured":"Waldmeier PC, Snaith J (1992) Brofaromine, a selective and reversible mao-A inhibitor that concomitantly inhibits serotonin uptake. Proceedings ACNP Meeting, Puerto Rico, p 15"},{"key":"BF02244898_CR48","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0014-2999(89)90016-2","volume":"169","author":"PC Waldmeier","year":"1989","unstructured":"Waldmeier PC, Stocklin K (1989) The reversible MAO-A inhibitor, brofaromine, inhibits serotonin uptake in vivo. Eur J Pharmacol 169:197\u2013204","journal-title":"Eur J Pharmacol"},{"key":"BF02244898_CR49","doi-asserted-by":"crossref","unstructured":"West ED, Dally PJ (1959) Effect of iproniazid in depressive syndrome. BMJ:1491\u20131494","DOI":"10.1136\/bmj.1.5136.1491"}],"container-title":["Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02244898.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02244898\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02244898","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T23:32:10Z","timestamp":1557876730000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02244898"}},"subtitle":["A double blind placebo controlled study"],"short-title":[],"issued":{"date-parts":[[1993,10]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1993,10]]}},"alternative-id":["BF02244898"],"URL":"https:\/\/doi.org\/10.1007\/bf02244898","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,10]]}}}