{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:12:13Z","timestamp":1791137533066,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1981,12,1]],"date-time":"1981-12-01T00:00:00Z","timestamp":376012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Inher Metab Disea"],"published-print":{"date-parts":[[1981,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The adult presenting Fanconi syndrome is a rare familial disorder. A 30\u2010year follow\u2010up of one of the original families in the literature is reported here. Two important points have emerged. Firstly, the inheritance in this family is dominant, not recessive as originally suggested, and there remains no good example in the literature of a recessive inheritance of this disorder. Second, in this family lactic aciduria and tubular proteinuria are probably the earliest manifestations of the disorder in childhood, with glycosuria and aminoaciduria developing in the second decade and osteomalacia from the start of the fourth decade. Glomerular function deteriorates slowly but is compatible with a normal lifespan.<\/jats:p>","DOI":"10.1007\/bf02263654","type":"journal-article","created":{"date-parts":[[2005,12,8]],"date-time":"2005-12-08T17:09:31Z","timestamp":1134061771000},"page":"211-215","source":"Crossref","is-referenced-by-count":28,"title":["The adult presenting idiopathic fanconi syndrome"],"prefix":"10.1002","volume":"4","author":[{"given":"D. P.","family":"Brenton","sequence":"first","affiliation":[{"name":"University College Medical School  London WC1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. A.","family":"Isenberg","sequence":"additional","affiliation":[{"name":"University College Medical School  London WC1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. C.","family":"Cusworth","sequence":"additional","affiliation":[{"name":"University College Medical School  London WC1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Garrod","sequence":"additional","affiliation":[{"name":"University College Medical School  London WC1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Krywawych","sequence":"additional","affiliation":[{"name":"University College Medical School  London WC1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. C. B.","family":"Stamp","sequence":"additional","affiliation":[{"name":"The Rayal National Orthopaedic Hospital  Great Portland Street London WC1"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1981,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(61)90163-2"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/an9729700958"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1951.tb02459.x"},{"key":"e_1_2_1_5_1","volume-title":"Advances in Pediatrics, 4","author":"Freudenberg F.","year":"1949"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(66)90114-8"},{"key":"e_1_2_1_7_1","first-page":"622","article-title":"Primary tubulopathies. II. A case of idiopathic glucoamino phosphate diabetes","volume":"16","author":"Illig R.","year":"1961","journal-title":"Helv. Paediatr. Acta"},{"key":"e_1_2_1_8_1","first-page":"1","article-title":"Hypophosphataemic glycosuric rickets (Fanconi syndrome)","volume":"8","author":"Linder G. C.","year":"1949","journal-title":"Clin. Proc."},{"key":"e_1_2_1_9_1","first-page":"780","volume-title":"Quantitative Clinical Chemistry, part 1","author":"Peters J. P.","year":"1946"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.36.185.90"},{"issue":"179","key":"e_1_2_1_11_1","first-page":"387","article-title":"Hypophosphataemic osteomalacia and Fanconi's syndrome of adult\u2010onset with dominant inheritance","volume":"45","author":"Smith R.","year":"1976","journal-title":"Q. J. 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