{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T04:56:10Z","timestamp":1754110570717},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1992,11,1]],"date-time":"1992-11-01T00:00:00Z","timestamp":720576000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[1992,11]]},"DOI":"10.1007\/bf02285096","type":"journal-article","created":{"date-parts":[[2006,1,25]],"date-time":"2006-01-25T18:36:58Z","timestamp":1138214218000},"page":"527-531","source":"Crossref","is-referenced-by-count":15,"title":["Intracolonic bioavailability of human calcitonin in man"],"prefix":"10.1007","volume":"43","author":[{"given":"C.","family":"Beglinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Born","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Muff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Drewe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L.","family":"Dreyfuss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mackay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. A.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02285096_CR1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1210\/jcem-35-1-175","volume":"35","author":"M Amoss","year":"1972","unstructured":"Amoss M, Rivier J, Guillemin R (1972) Release of gonadotropins by oral administration of synthetic LRF or a tripeptide fragment of LRF. J Clin Endocrinol Metab 35:175\u2013177","journal-title":"J Clin Endocrinol Metab"},{"key":"BF02285096_CR2","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1056\/NEJM198101293040505","volume":"304","author":"LA Austin","year":"1981","unstructured":"Austin LA, Heath III IH (1981) Calcitonin. Physiology and pathophysiology. N Engl J Med 304:269\u2013278","journal-title":"N Engl J Med"},{"key":"BF02285096_CR3","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1056\/NEJM197104012841301","volume":"284","author":"OLM Bijvoet","year":"1971","unstructured":"Bijvoet OLM, Van der Sluys Veer J, De Vries HR, Van Koppen ATJ (1971) Natriuretic effect of calcitonin in man. N Engl J Med 284:681\u2013688","journal-title":"N Engl J Med"},{"key":"BF02285096_CR4","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/BF02555225","volume":"41","author":"T Buclin","year":"1987","unstructured":"Buclin T, Randin JP, Jacquet AF, Azria M, Attinger M, Gomez F, Burckhardt P (1987) The effect of rectal and nasal administration of salmon calcitonin in normal subjects. Calcif Tissue Int 41:252\u2013258","journal-title":"Calcif Tissue Int"},{"key":"BF02285096_CR5","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1210\/endo-65-1-118","volume":"65","author":"E Danforth","year":"1959","unstructured":"Danforth E, Moore RO (1959) Intestinal absorption of insulin in the rat. Endocrinology 65:118\u2013123","journal-title":"Endocrinology"},{"key":"BF02285096_CR6","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1530\/acta.0.0800465","volume":"80","author":"FM Dietrich","year":"1975","unstructured":"Dietrich FM, Hunziker WH, Fischer JA (1975) Synthetic human calcitonin: analysis of antibodies obtained from various animal species and determination of immunoreactive hormone in human sera. Acta Endocrinol (Copenh) 80: 465\u2013486","journal-title":"Acta Endocrinol (Copenh)"},{"key":"BF02285096_CR7","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/0016-5085(91)90651-Z","volume":"100","author":"G Fricker","year":"1991","unstructured":"Fricker G, Bruns C, Munzer J, Briner U, Albert R, Kissel T, Vonderscher J (1991) Intestinal absorption of the octapeptide SMS 201995 visualized by fluorescence derivatization. Gastroenterology 100:1544\u20131552","journal-title":"Gastroenterology"},{"key":"BF02285096_CR8","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0169-409X(91)90051-D","volume":"7","author":"DR Friend","year":"1991","unstructured":"Friend DR (1991) Colon-specific drug delivery. Adv Drug Deliv Rev 7:149\u2013199","journal-title":"Adv Drug Deliv Rev"},{"key":"BF02285096_CR9","first-page":"E848","volume":"257","author":"MP Gnaedinger","year":"1989","unstructured":"Gnaedinger MP Uehlinger DE, Weidmann P, Sha SG, Muff R, Born W, Rascher W Fischer JA (1989) Distinct hemodynamic and renal effects of calcitonin gene-related peptide and calcitonin in men. Am J Physiol 257: E848-E854","journal-title":"Am J Physiol"},{"key":"BF02285096_CR10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0009-8981(72)90492-5","volume":"41","author":"BC Goverde","year":"1972","unstructured":"Goverde BC, Veenkamp FJN (1972) Routine assay of total urinary hydroxyproline based on resin-catalysed hydrolysis. Clin Chim Acta 41: 29\u201340","journal-title":"Clin Chim Acta"},{"key":"BF02285096_CR11","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1172\/JCI106770","volume":"50","author":"HG Haas","year":"1971","unstructured":"Haas HG, Dambacher MA, Guncaga J, Lauffenburger T (1971) Renal effects of calcitonin and parathyroid extract in man. Studies in hypoparathyroidism. J Clin Invest 50:2689\u20132702","journal-title":"J Clin Invest"},{"key":"BF02285096_CR12","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1042\/cs0820589","volume":"82","author":"J Hastewell","year":"1992","unstructured":"Hastewell J, Lynch S, Williamson I, Fox R, Mackay M (1992) Absorption of human calcitonin across the rat colon in vivo. Clin Sci: 82:589\u2013594","journal-title":"Clin Sci"},{"key":"BF02285096_CR13","doi-asserted-by":"crossref","first-page":"E15","DOI":"10.1152\/ajpcell.1979.236.1.C15","volume":"236","author":"R Huwyler","year":"1979","unstructured":"Huwyler R, Born W, Ohnhaus EE, Fischer JA (1979) Plasma kinetics and urinary excretion of exogenous human and salmon calcitonin in man. Am J Physiol 236: E15-E19","journal-title":"Am J Physiol"},{"key":"BF02285096_CR14","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1016\/0024-3205(82)90673-7","volume":"31","author":"M Kidron","year":"1982","unstructured":"Kidron M, Bar-On H, Berry EM, Ziv E (1982) The absorption of insulin from various regions of the rat intestine. Life Sci 31: 2837\u20132841","journal-title":"Life Sci"},{"key":"BF02285096_CR15","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/BF00544562","volume":"33","author":"E K\u00f6hler","year":"1987","unstructured":"K\u00f6hler E, Duberow-Drewe M, Drewe J, Ribes G, Loubati\u00e9res-Mariani MM, Mazer N, Gyr K, Beglinger C (1987) Absorption of an aqueous solution of a new synthetic somatostatin analogue administered to man by gavage. Eur J Clin Pharmacol 33: 167\u2013171","journal-title":"Eur J Clin Pharmacol"},{"key":"BF02285096_CR16","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1530\/acta.0.1120457","volume":"112","author":"S Lundin","year":"1986","unstructured":"Lundin S, Vilhardt H (1986) Absorption of 1-deamino-8-D-arginine vasopressin from different regions of the gastrointestinal tract in rabbits. Acta Endocrinol (Copenh) 112: 457\u2013460","journal-title":"Acta Endocrinol (Copenh)"},{"key":"BF02285096_CR17","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/02648725.1990.10647871","volume":"8","author":"M Mackay","year":"1990","unstructured":"Mackay M (1990) Delivery of recombinant peptide and protein drugs. Biotechnology Genetic Engineering Rev 8:251\u2013278","journal-title":"Biotechnology Genetic Engineering Rev"},{"key":"BF02285096_CR18","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0378-5173(86)90007-4","volume":"34","author":"JA Moore","year":"1986","unstructured":"Moore JA, Pletcher SA, Ross MJ (1986) Absorption enhancement of growth hormone from the gastrointestinal tract of rats. Int J Pharm 34:35\u201343","journal-title":"Int J Pharm"},{"key":"BF02285096_CR19","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0002-9343(90)90297-Q","volume":"89","author":"R Muff","year":"1990","unstructured":"Muff R, Dambacher MA, Perrenoud A, Simon C, Fischer JA (1990) Efficacy of intranasal human calcitonin in patients with Paget's disease refractory to salmon calcitonin. Am J Med 89:181\u2013184","journal-title":"Am J Med"},{"key":"BF02285096_CR20","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/S0021-9258(19)75816-5","volume":"262","author":"JB Petermann","year":"1987","unstructured":"Petermann JB, Born W Chang J-Y, Fischer JA (1987) Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord. J Biol Chem 262: 542\u2013545","journal-title":"J Biol Chem"},{"key":"BF02285096_CR21","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1126\/science.3526553","volume":"233","author":"M Saffran","year":"1986","unstructured":"Saffran M, Kumar GS, Savariar C, Burnham JC, Williams F, Neckers DC (1986) A new approach to the oral administration of insulin and other peptide drugs. Science (Wash) 233: 1081\u20131084","journal-title":"Science (Wash)"},{"key":"BF02285096_CR22","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0378-5173(86)90069-4","volume":"30","author":"E Touitou","year":"1986","unstructured":"Touitou E, Rubinstein A (1986) Targeted enteral delivery of insulin to rats. Int J Pharm 30: 95\u201399","journal-title":"Int J Pharm"},{"key":"BF02285096_CR23","first-page":"293","volume-title":"Molecular Endocrinology","author":"R Ziegler","year":"1979","unstructured":"Ziegler R, Holz G, Raue F, Streibl W (1979) Nasal application of human calcitonin in Paget's disease of bone. In: MacIntyre I, Szelke M (eds) Molecular Endocrinology. Elsevier, Amsterdam, pp 293\u2013300"}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02285096.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02285096\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02285096","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T05:30:20Z","timestamp":1627018220000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02285096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,11]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1992,11]]}},"alternative-id":["BF02285096"],"URL":"https:\/\/doi.org\/10.1007\/bf02285096","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,11]]}}}