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There was a significant difference in the mean aqueous taurine concentration in each of the three groups. The Bu rabbits had only 29% of the MCV rabbits' level while the JAX rabbits were intermediate with 56% of the MCV level. It is suggested that some of the JAX rabbits may be heterozygous and the Bu rabbits homozygous for a semi\u2010dominant allele of a gene that is less efficient in taurine transport in the ciliary epithelium than the normal allele represented by the MCV animals.<\/jats:p>","DOI":"10.1007\/bf02310874","type":"journal-article","created":{"date-parts":[[2006,2,15]],"date-time":"2006-02-15T15:54:22Z","timestamp":1140018862000},"page":"163-166","source":"Crossref","is-referenced-by-count":0,"title":["Evidence for an hereditary defect in taurine transport in the ciliary epithelium of an inbred strain of rabbits"],"prefix":"10.1002","volume":"6","author":[{"given":"T. M.","family":"Harris","sequence":"first","affiliation":[{"name":"Departments of Anatomy, Human Genetics and Pediatrics and Ophthalmology Medical College of Virginia  Box 709 Richmond VA 23298 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. S.","family":"Nance","sequence":"additional","affiliation":[{"name":"Departments of Anatomy, Human Genetics and Pediatrics and Ophthalmology Medical College of Virginia  Box 709 Richmond VA 23298 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. B.","family":"Sheppard","sequence":"additional","affiliation":[{"name":"Departments of Anatomy, Human Genetics and Pediatrics and Ophthalmology Medical College of Virginia  Box 709 Richmond VA 23298 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. R.","family":"Fox","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory  Bar Harbor ME USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1983,1,24]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108258"},{"key":"e_1_2_1_3_1","first-page":"686","article-title":"Absolute levels of some free amino acids in normal and biologically fractionated retinas","volume":"12","author":"Cohen A. I.","year":"1973","journal-title":"Invest. Ophthal."},{"key":"e_1_2_1_4_1","volume-title":"Physiology of the Eye","author":"Davson H.","year":"1980"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1978.tb06642.x"},{"key":"e_1_2_1_6_1","volume-title":"Handbook on Genetically Standardized JAX Rabbits","author":"Fox R. 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