{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T07:59:14Z","timestamp":1775203154377,"version":"3.50.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1996,10,1]],"date-time":"1996-10-01T00:00:00Z","timestamp":844128000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Gastroenterol"],"published-print":{"date-parts":[[1996,10]]},"DOI":"10.1007\/bf02347625","type":"journal-article","created":{"date-parts":[[2006,3,15]],"date-time":"2006-03-15T17:57:28Z","timestamp":1142445448000},"page":"728-731","source":"Crossref","is-referenced-by-count":9,"title":["Pancreatic cancer and hypercalcemia associated with von Recklinghausen's disease"],"prefix":"10.1007","volume":"31","author":[{"given":"Mitsuyoshi","family":"Yamamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigekazu","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Mugikura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issei","family":"Tachibana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshimitsu","family":"Ogami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Otsuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02347625_CR1","first-page":"2055","volume-title":"Harnson's principles of internal medicine","author":"S Vernes","year":"1991","unstructured":"Vernes S, Caviness JR. Neurocutaneous syndromes. In: Wilson JD, Braunwald EB, Isselbacher KL, Isselbacher KJ, Petersdorf RG, Martin JB, Fauci AS, Root RK (eds) Harnson's principles of internal medicine. 12th ed. New York: McGraw-Hill, 1991;2055\u20132056.","edition":"12th ed."},{"key":"BF02347625_CR2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.7326\/0003-4819-107-5-785_1","volume":"107","author":"F Paraf","year":"1987","unstructured":"Paraf F, Poynard T, Bedossa P, et al. Adenocarcinoma of Vater's ampulla and von Recklinghausen disease. Ann Int Med 1987; 107:785.","journal-title":"Ann Int Med"},{"key":"BF02347625_CR3","doi-asserted-by":"crossref","first-page":"772","DOI":"10.7326\/0003-4819-106-5-772_2","volume":"106","author":"DP Sprengers","year":"1987","unstructured":"Sprengers DP, Knockaert DC, Steenbergen WV, et al. Primary bile duct cancer and von Recklinghausen disease. Ann Int Med 1987;106:772.","journal-title":"Ann Int Med"},{"key":"BF02347625_CR4","first-page":"2474","volume":"86","author":"T Niiyama","year":"1989","unstructured":"Niiyama T, Toujinbara H, Saeki K, et al. Two cases of von Recklinghausen's disease with malignant tumor (in Japanese). Jpn J Gastroenterol 1989;86:2474\u20132479.","journal-title":"Jpn J Gastroenterol"},{"key":"BF02347625_CR5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.2169\/internalmedicine.33.167","volume":"33","author":"Y Shimizu","year":"1994","unstructured":"Shimizu Y, Tsuchiya S, Watanabe S, et al. von Recklinghausen's disease with lung cancer derived from the wall of emphysematous bullae. Int Med 1994;33:167\u2013171.","journal-title":"Int Med"},{"key":"BF02347625_CR6","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1056\/NEJM198809013190906","volume":"319","author":"AE Broadus","year":"1988","unstructured":"Broadus AE, Mangin M, Ikeda K, et al. Humoral hypercalcemia of cancer. N Engl J Med 1988;319:556\u2013563.","journal-title":"N Engl J Med"},{"key":"BF02347625_CR7","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1093\/clinchem\/37.5.678","volume":"37","author":"WA Ratcliffe","year":"1991","unstructured":"Ratcliffe WA, Norbury S, Heath DA, et al. Development and validation of an immunoradiometric assay for parathyrin-related protein in unextracted plasma. Clin Chem 1991;37:678\u2013685.","journal-title":"Clin Chem"},{"key":"BF02347625_CR8","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0026-0495(86)90010-7","volume":"35","author":"N Nagata","year":"1986","unstructured":"Nagata N, Kugai N, Maemura M, et al. Enhancement of cyclic adenosine monophosphate content in bone cells by the factor extracted from a pancreatic cancer associated with hypercalcemia. Metabolism 1986;35:529\u2013534.","journal-title":"Metabolism"},{"key":"BF02347625_CR9","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/00365519209088368","volume":"52","author":"KI Birkeland","year":"1992","unstructured":"Birkeland KI, Gallefoss F, Olsson S, et al. Primary hyperparathyroidism or hypercalcemia of malignancy? Scand J Clin Lab Invest 1992;52:347\u2013349.","journal-title":"Scand J Clin Lab Invest"},{"key":"BF02347625_CR10","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/0046-8177(92)90399-N","volume":"23","author":"BA Miraliakbari","year":"1992","unstructured":"Miraliakbari BA, Asa SL, Boudreau SF. Parathyroid hormone-like peptide in pancreatic endocrine carcinoma and adenocarcinoma associated with hypercalcemia. Hum Pathol 1992;23:884\u2013887.","journal-title":"Hum Pathol"},{"key":"BF02347625_CR11","first-page":"1580","volume":"89","author":"I Tachibana","year":"1994","unstructured":"Tachibana I, Nakano S, Akiyama T, et al. Parathyroid hormone-related protein mediates hypercalcemia in an exocrine pancreatic cancer. Am J Gastroenterol 1994;89:1580\u20131581.","journal-title":"Am J Gastroenterol"},{"key":"BF02347625_CR12","first-page":"437","volume":"78","author":"J Schonebeck","year":"1970","unstructured":"Schonebeck J, Ljungberg O. Recklinghausen's disease: A multifaceted syndrome. Acta Pathol Microbiol Scand 1970;78: 437\u2013442.","journal-title":"Acta Pathol Microbiol Scand"},{"key":"BF02347625_CR13","first-page":"635","volume":"60","author":"T Horita","year":"1988","unstructured":"Horita T, Katou T, Tanaka R, Otsuka N. The neuronotropic factor (NTF) in neurofibroma (von-Recklinghausen's disease) (in Japanese). Seikagaku 1988;60:635.","journal-title":"Seikagaku"},{"key":"BF02347625_CR14","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1056\/NEJM198604173141603","volume":"314","author":"SA Sorensen","year":"1986","unstructured":"Sorensen SA, Mulvihill JJ, Nielsen A. Long-term follow-up of von Recklinghausen neurofibromatosis: Survival and malignant nenoplasms. J Engl J Med 1986;314:1010\u20131015.","journal-title":"J Engl J Med"},{"key":"BF02347625_CR15","first-page":"19","volume":"15","author":"DA Kossak","year":"1969","unstructured":"Kossak DA, Gonzales CL, Doria OS. (in Portuguese with English abstract). Arquiv hospitals da Santa Casa del S\u00e3o Paulo 1969;15:19\u201320.","journal-title":"Arquiv hospitals da Santa Casa del S\u00e3o Paulo"},{"key":"BF02347625_CR16","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1001\/archderm.1973.01620200061017","volume":"107","author":"WA Knight","year":"1973","unstructured":"Knight WA, Murphy WK, Gottlieb JA. Neurofibromatosis associated with malignant neurofibromas. Arch Dermatol 1973;107:747\u2013750.","journal-title":"Arch Dermatol"},{"key":"BF02347625_CR17","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1002\/1097-0142(197703)39:3<1264::AID-CNCR2820390337>3.0.CO;2-C","volume":"39","author":"RT Keller","year":"1977","unstructured":"Keller RT, Logan GM. Adenocarcinoma of the pancrease associated with neurofibromatosis. Cancer 1977;39:1246\u20131264.","journal-title":"Cancer"},{"key":"BF02347625_CR18","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/0002-9343(87)90096-9","volume":"82","author":"Y Niv","year":"1987","unstructured":"Niv Y, Abuavid S, Oren M. Adenocarcinoma of pancreas and duodenum associated with cutaneous neurofibromatosis. Am J Med 1987;82:384\u2013385.","journal-title":"Am J Med"},{"key":"BF02347625_CR19","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/00000658-198709000-00015","volume":"206","author":"MM Connolly","year":"1987","unstructured":"Connolly MM, Dawson PJ, Michelassi F, et al. Survival in 1001 patients with carcinoma of the pancreas Ann Surg 1987;206:366\u2013373.","journal-title":"Ann Surg"},{"key":"BF02347625_CR20","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1001\/jama.1975.03260130039021","volume":"233","author":"MJ Sands","year":"1975","unstructured":"Sands MJ, McDonough MT, Cohen AM, et al. Fatal malignant degeneration in multiple neurofibromatosis. J Am Med Assoc 1975;233:1381\u20131382.","journal-title":"J Am Med Assoc"},{"key":"BF02347625_CR21","first-page":"411","volume":"68","author":"HH Storm","year":"1985","unstructured":"Storm HH, Jensen OM, Ewertz M, et al. Multiple primary cancers in Denmark, 1943\u201380. Natl Canc Inst Monoger 1985;68:411\u2013430.","journal-title":"Natl Canc Inst Monoger"},{"key":"BF02347625_CR22","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0092-8674(90)90253-B","volume":"62","author":"RM Cawthon","year":"1990","unstructured":"Cawthon RM, Weiss R, Xu G, et al. A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations. Cell 1990;62:193\u2013201.","journal-title":"Cell"},{"key":"BF02347625_CR23","first-page":"559","volume":"62","author":"G Xu","year":"1990","unstructured":"Xu G, O'Connell P, Viskochil D, et al. The neurofibrosis type 1 gene encodes a protein related to GAP. Cell 1990;62:559\u2013608.","journal-title":"Cell"},{"key":"BF02347625_CR24","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1126\/science.2833817","volume":"240","author":"H Adrai","year":"1988","unstructured":"Adrai H, Lowy DR, Wilumsen BM, Der CJ. Guanosine triphosphate activating protein (GAP) interacts with the p21 ras effector binding domain. Science 1988;240:518\u2013521.","journal-title":"Science"},{"key":"BF02347625_CR25","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1002\/1097-0142(19930215)71:4<1309::AID-CNCR2820710423>3.0.CO;2-M","volume":"71","author":"R Vassilopoulou-Sellin","year":"1993","unstructured":"Vassilopoulou-Sellin R, Newman BM, Taylor SH, et al. Incidence of hypercalcemia in patients with malignancy referred to a comprehensive cancer center. Cancer 1993;71:1309\u20131312.","journal-title":"Cancer"},{"key":"BF02347625_CR26","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1210\/endo-124-5-2172","volume":"124","author":"K Sato","year":"1989","unstructured":"Sato K, Fujii K, Kasono K, et al. Parathyroid hormone related protein and interleukin-1 \u03b1 synergistically stimulate bone resorption in vitro and increase the serum calcium concentration in vivo. Endocrinology 1989;124:2172\u20132178.","journal-title":"Endocrinology"},{"key":"BF02347625_CR27","first-page":"737","volume":"53","author":"T Yoneda","year":"1993","unstructured":"Yoneda T, Nakai M, Moriyama K, et al. Neutralizing antibodies to human interleukin 6 reverse hypercalcemia associated with a human squamous carcinoma. Cancer Res 1993;53:737\u2013740.","journal-title":"Cancer Res"},{"key":"BF02347625_CR28","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1172\/JCI115106","volume":"87","author":"T Yoneda","year":"1991","unstructured":"Yoneda T, Alsina MA, Chavez JB, et al. Evidence that tumor necrosis factor play a pathogenetic role in the paraneoplastic syndromes of cachexia, hypercalcemia and leukocytosis in a human tumor in nude mice. J Clin Invest 1991;87:977\u2013985.","journal-title":"J Clin Invest"}],"container-title":["Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02347625.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02347625\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02347625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T06:24:14Z","timestamp":1586759054000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02347625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,10]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1996,10]]}},"alternative-id":["BF02347625"],"URL":"https:\/\/doi.org\/10.1007\/bf02347625","relation":{},"ISSN":["0944-1174","1435-5922"],"issn-type":[{"value":"0944-1174","type":"print"},{"value":"1435-5922","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,10]]}}}