{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T02:45:04Z","timestamp":1771641904598,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1995,4,1]],"date-time":"1995-04-01T00:00:00Z","timestamp":796694400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Gastroenterol"],"published-print":{"date-parts":[[1995,4]]},"DOI":"10.1007\/bf02348662","type":"journal-article","created":{"date-parts":[[2006,3,16]],"date-time":"2006-03-16T01:34:23Z","timestamp":1142472863000},"page":"177-182","source":"Crossref","is-referenced-by-count":36,"title":["Significance of superoxide dismutase (SOD) in human colorectal cancer tissue: Correlation with malignant intensity"],"prefix":"10.1007","volume":"30","author":[{"given":"Akira","family":"Satomi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saburou","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiju","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moriyuki","family":"Matsuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02348662_CR1","doi-asserted-by":"crossref","first-page":"6049","DOI":"10.1016\/S0021-9258(18)63504-5","volume":"244","author":"JM McCord","year":"1969","unstructured":"McCord JM, Fridovich I. Superoxide dismutase: An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244:6049\u20136055.","journal-title":"J Biol Chem"},{"key":"BF02348662_CR2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/carcin\/9.2.203","volume":"9","author":"Y Nakamura","year":"1988","unstructured":"Nakamura Y, Gindhart TD, Winterstein D, et al. Early superoxide dismutase-sensitive event promotes neoplastic transformation in mucose epidermal JB6 cells. Carcinogenesis 1988;9: 203\u2013207.","journal-title":"Carcinogenesis"},{"key":"BF02348662_CR3","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/bjc.1985.18","volume":"51","author":"CEJ Hoffman","year":"1985","unstructured":"Hoffman CEJ, Webster NR, Wiggins PA, et al. Free radical detoxifying systems in human colorectal cancer. Br J Cancer 1985;51:127\u2013129.","journal-title":"Br J Cancer"},{"key":"BF02348662_CR4","first-page":"2759","volume":"38","author":"JA Sykes","year":"1978","unstructured":"Sykes JA, McCormack FX Jr, O'Brien TJ. A preliminary study of the superoxide dismutase content of some human tumors. Cancer Res 1978;38:2759\u20132762.","journal-title":"Cancer Res"},{"key":"BF02348662_CR5","first-page":"3844","volume":"49","author":"BK Sinha","year":"1989","unstructured":"Sinha BK, Mimnaugh EG, Rajagopalan S, et al. Adriamycine activation and oxygen free radical formation in human breast tumor cells: Protective role of glutathione peroxidase in adriamycine resistance. Cancer Res 1989;49:3844\u20133848.","journal-title":"Cancer Res"},{"key":"BF02348662_CR6","volume-title":"General rules for clinical and pathological studies on cancer of colon, rectum and anus","author":"Japanese Research Society for Cancer of Colon and Rectum","year":"1985","unstructured":"Japanese Research Society for Cancer of Colon and Rectum. General rules for clinical and pathological studies on cancer of colon, rectum and anus. 4th ed. Tokyo: Kanehara, 1985.","edition":"4th ed."},{"key":"BF02348662_CR7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3109\/10715769309056s185","volume":"19","author":"M Sonoda","year":"1993","unstructured":"Sonoda M, Asakuno G, Matsuki M, et al. Radical trapping by PBN during reperfusion in rabbit gastric mucosa. Free Rad Res Commun 1993;19:185\u2013191.","journal-title":"Free Rad Res Commun"},{"key":"BF02348662_CR8","volume-title":"Macintosh medical statistical manual","author":"O Nagata","year":"1994","unstructured":"Nagata O. Macintosh medical statistical manual. Tokyo: Shinko-koueki, 1994."},{"key":"BF02348662_CR9","first-page":"1955","volume":"42","author":"SL Marklund","year":"1982","unstructured":"Marklund SL, Westman NG, Lundgren E, et al. Copper and zinc containing superoxide dismutase, manganese containing superoxide dismutase, catalase, and glutathione peroxidase in normal and neoplastic human cell lines and normal human tissues. Cancer Res 1982;42:1955\u20131961.","journal-title":"Cancer Res"},{"key":"BF02348662_CR10","first-page":"3686","volume":"40","author":"IB Bize","year":"1980","unstructured":"Bize IB, Oberley LW, Morris HP. Superoxide radical in Morris hepatoma. Cancer Res 1980;40:3686\u20133693.","journal-title":"Cancer Res"},{"key":"BF02348662_CR11","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/0005-2744(75)90059-5","volume":"403","author":"O Dionisi","year":"1975","unstructured":"Dionisi O, Galeotti T, Terranova T, et al. Superoxide radicals and hydrogen peroxide formation in mitochondria from normal and neoplastic tissues. Biochem Biophys Acta 1975;403:292\u2013300.","journal-title":"Biochem Biophys Acta"},{"key":"BF02348662_CR12","first-page":"377","volume":"65","author":"DP Loven","year":"1980","unstructured":"Loven DP, Oberley LW, Rousseau FM, et al. Superoxide dismutase activity in 1,2-dimethylhydrazine-induced rat colon adenocarcinoma. JNCI 1980;65:377\u2013381","journal-title":"JNCI"},{"key":"BF02348662_CR13","first-page":"2167","volume":"47","author":"M Mukai","year":"1987","unstructured":"Mukai M, Shinkai K, Tateish R, et al. Macrophage potentiation of invasive capacity of ascites hepatoma cells. Cancer Res 1987; 47:2167\u20132171.","journal-title":"Cancer Res"},{"key":"BF02348662_CR14","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1126\/science.3975611","volume":"227","author":"SA Weitzman","year":"1985","unstructured":"Weitzman SA. Phagocytes as carcinogens: Malignant transformation produced by human neurtrophils. Science 1985,227:1231\u20131233.","journal-title":"Science"},{"key":"BF02348662_CR15","first-page":"330","volume":"2","author":"K Sinkai","year":"1991","unstructured":"Sinkai K, Mukai M, Imamura F, et al. Potentiation of invasive capacity of rat ascites hepatoma cells by free radicals. J Act Oxyg Free Rad 1991;2:330\u2013336.","journal-title":"J Act Oxyg Free Rad"},{"key":"BF02348662_CR16","first-page":"794","volume":"51","author":"TP Szatrowski","year":"1991","unstructured":"Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 1991;51:794\u2013798.","journal-title":"Cancer Res"},{"key":"BF02348662_CR17","first-page":"313","volume":"3","author":"H Iizuka","year":"1992","unstructured":"Iizuka H, Hashimoto Y, Kobayashi T. Oxygen and superoxide dismutase in epidermis: Its relation to keratinocyte proliferation. J Act Oxyg Free Rad 1992;3:313\u2013321.","journal-title":"J Act Oxyg Free Rad"},{"key":"BF02348662_CR18","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/0003-9861(85)90056-6","volume":"240","author":"J Blum","year":"1985","unstructured":"Blum J, Fridovich I. Inactivation of glutathione peroxidase by superoxide radical. Arch Biochem Biophys 1985;240:500\u2013508.","journal-title":"Arch Biochem Biophys"},{"key":"BF02348662_CR19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1146\/annurev.bi.44.070175.001051","volume":"44","author":"I Fridovich","year":"1975","unstructured":"Fridovich I, Superoxide dismutase. Ann Rev Biochem 1975;44:147\u2013159.","journal-title":"Ann Rev Biochem"},{"key":"BF02348662_CR20","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1093\/carcin\/5.12.1547","volume":"5","author":"U Armato","year":"1984","unstructured":"Armato U, Andreis PG, Romano F. Exogenous Cu, Zn-superoxide dismutase suppresses the stimulation of neonatal rat hepatocyte growth by tumor promoters. Carcinogenesis 1984;5:1547\u20131554.","journal-title":"Carcinogenesis"},{"key":"BF02348662_CR21","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1152\/physrev.1990.70.1.115","volume":"70","author":"RS Rana","year":"1990","unstructured":"Rana RS, Hokin LE. Role of phosphoinositides in transmembrane signaling. Physiol Rev 1990;70:115\u2013124.","journal-title":"Physiol Rev"},{"key":"BF02348662_CR22","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0309-1651(81)80005-7","volume":"5","author":"S Honda","year":"1981","unstructured":"Honda S, Senshu T, Matsuno M. The oxygen susceptibility of cultured Hela cells and the cell cycle. Cell Biol Internal Rep 1981;5:553\u2013558.","journal-title":"Cell Biol Internal Rep"},{"key":"BF02348662_CR23","first-page":"71","volume":"4","author":"H Iwagaki","year":"1993","unstructured":"Iwagaki H, Kashino H, Matsubara N, et al. Free radicals and lipid peroxidation in gastrointestinal tumors. Magn Reson Med 1993;4:71\u201374.","journal-title":"Magn Reson Med"},{"key":"BF02348662_CR24","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1042\/bj2500247","volume":"250","author":"KH Cheeseman","year":"1988","unstructured":"Cheeseman KH, Emery S, Maddix SP, et al. Studies on lipid peroxidation in normal and tumour tissues. Biochem J 1988; 250:247\u2013252.","journal-title":"Biochem J"},{"key":"BF02348662_CR25","first-page":"15","volume":"69","author":"RC Wolley","year":"1982","unstructured":"Wolley RC, Schreiber K, Koss LG, et al. DNA distribution in human colon carcinomas and its relationship to clinical behavior. JNCI 1982;69:15\u201322.","journal-title":"JNCI"},{"key":"BF02348662_CR26","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/bjc.1990.393","volume":"62","author":"NC Armitage","year":"1990","unstructured":"Armitage NC, Ballantyne KG, Evans DF, et al The influence of tumour cell DNA content on survival in colorectal cancer: A detailed analysis. Br J Cancer 1990;62:852\u2013856.","journal-title":"Br J Cancer"},{"key":"BF02348662_CR27","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/bjc.1990.420","volume":"62","author":"M Kouri","year":"1990","unstructured":"Kouri M, Pyrhonen S, Mecklin JP, et al. The prognostic value of DNA ploidy in colorectal carcinoma: A prospective study. Br J Cancer 1990;62:976\u2013981.","journal-title":"Br J Cancer"},{"key":"BF02348662_CR28","first-page":"595","volume":"99","author":"K Hatsuda","year":"1990","unstructured":"Hatsuda K. SOD and peroxidase activities in endometrial cancer and their effects on sensitivity to ADM. J Kyoto Pref Univ Med 1990;99:595\u2013605.","journal-title":"J Kyoto Pref Univ Med"},{"key":"BF02348662_CR29","doi-asserted-by":"crossref","first-page":"4515","DOI":"10.1073\/pnas.83.12.4514","volume":"83","author":"JH Doroshow","year":"1986","unstructured":"Doroshow JH. Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones. Proc Natl Acad Sci USA 1986;83:4515\u20134518.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF02348662_CR30","first-page":"75","volume":"4","author":"H Iwagaki","year":"1993","unstructured":"Iwagaki H, Matsubara N, Mizukawa K, et al. The possible involvement of free radical scavenging properties in interferon-\u03b3. Magn Reson Med 1993;4:75\u201378.","journal-title":"Magn Reson Med"},{"key":"BF02348662_CR31","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1126\/science.2981433","volume":"227","author":"PA Cerutti","year":"1981","unstructured":"Cerutti PA. Prooxidant states and tumor promotion. Science 1981;227:375\u2013381.","journal-title":"Science"}],"container-title":["Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02348662.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02348662\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02348662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T23:29:44Z","timestamp":1627169384000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02348662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,4]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1995,4]]}},"alternative-id":["BF02348662"],"URL":"https:\/\/doi.org\/10.1007\/bf02348662","relation":{},"ISSN":["0944-1174","1435-5922"],"issn-type":[{"value":"0944-1174","type":"print"},{"value":"1435-5922","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,4]]}}}