{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T21:13:59Z","timestamp":1780694039375,"version":"3.54.1"},"reference-count":70,"publisher":"Springer Science and Business Media LLC","issue":"5-6","license":[{"start":{"date-parts":[[1984,11,1]],"date-time":"1984-11-01T00:00:00Z","timestamp":468115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1984,11,1]],"date-time":"1984-11-01T00:00:00Z","timestamp":468115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antonie van Leeuwenhoek"],"published-print":{"date-parts":[[1984,11]]},"DOI":"10.1007\/bf02386238","type":"journal-article","created":{"date-parts":[[2006,4,9]],"date-time":"2006-04-09T22:37:19Z","timestamp":1144622239000},"page":"745-761","source":"Crossref","is-referenced-by-count":14,"title":["The digestive tract in immunocompromised patients: importance of maintaining its resistance to colonization, especially in hospital in-patients and those taking antibiotics"],"prefix":"10.1007","volume":"50","author":[{"given":"D.","family":"van der Waaij","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02386238_CR1","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1093\/ajcn\/30.11.1880","volume":"30","author":"G. D. Abrams","year":"1977","unstructured":"Abrams, G. D. 1977. Microbial effects on mucosal structure and function. \u2014 Am. J. Clin. Nutr.30: 1880\u20131886.","journal-title":"Am. J. Clin. Nutr."},{"key":"BF02386238_CR2","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1038\/266448a0","volume":"266","author":"B. Allweiss","year":"1977","unstructured":"Allweiss, B., Dostal, J., Carey, K. E., Edwards, T. F. andFreter, R. 1977. The role of chemotaxis in the ecology of bacterial pathogens of mucosal surfaces. \u2014 Nature (London)266: 448\u2013450.","journal-title":"Nature"},{"key":"BF02386238_CR3","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1128\/iai.29.3.1073-1081.1980","volume":"29","author":"R. Berg","year":"1980","unstructured":"Berg, R. 1980. Inhibition of translocation from the gastrointestinal tract by normal cecal flora in gnotobiotic or antibiotic-decontaminated mice. \u2014 Infect. Immun.29: 1073\u20131081.","journal-title":"Infect. Immun."},{"key":"BF02386238_CR4","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1128\/iai.23.3.559-563.1979","volume":"23","author":"B. M. Byrne","year":"1979","unstructured":"Byrne, B. M. andDankert, J. 1979. Volatile fatty acids and anaerobic flora in the gastro-intestinal tract of mice under various conditions. \u2014 Infect. Immun.23: 559\u2013563.","journal-title":"Infect. Immun."},{"key":"BF02386238_CR5","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1093\/infdis\/139.6.621","volume":"139","author":"A. W. Chow","year":"1979","unstructured":"Chow, A. W., Taylor, Ph. R., Yoshikawa, T. T. andGuze, L. B. 1979. A nosocomial outbreak of infections due to multiply resistantProteus mirabilis: role of intestinal colonization as a major reservoir. \u2014 J. Infect. Dis.139:621\u2013627.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR6","doi-asserted-by":"crossref","first-page":"555","DOI":"10.7326\/0003-4819-95-5-555","volume":"95","author":"A. W. Dekker","year":"1982","unstructured":"Dekker, A. W., Rosenberg-Arska, M., Sixma, J. J. andVerhoef, J. 1982. Prevention of infection by co-trimoxazole in patients with acute non-lymphocytic leukemia. \u2014 Ann. Intern. Med.95: 555\u2013559.","journal-title":"Ann. Intern. Med."},{"key":"BF02386238_CR7","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/BF01816727","volume":"10","author":"H. G. De Vries-Hospers","year":"1982","unstructured":"De Vries-Hospers, H. G., Mulder, N. H., Sleijfer, D. T. andVan Saene, H. K. F. 1982. The effect of amphotericin B lozenges on the presence and the number ofCandida cells in the oropharynx of neutropenic patients. \u2014 Infection10: 71\u201375.","journal-title":"Infection"},{"key":"BF02386238_CR8","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1128\/AAC.19.5.813","volume":"19","author":"H. G. De Vries-Hospers","year":"1981","unstructured":"De Vries-Hospers, H. G., Sleijfer, D. T., Mulder, N. H., Van der Waaij, D., Nieweg, H. O. andVan Saene, H. K. F. 1981. Bacteriological aspects of selective decontamination of the digestive tract as a method of infection prevention in granulocytopenic patients. \u2014 Antimicrob. Agents Chemother.19: 813\u2013820.","journal-title":"Antimicrob. Agents Chemother."},{"key":"BF02386238_CR9","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/infdis\/142.2.273","volume":"142","author":"P. Echeverria","year":"1980","unstructured":"Echeverria, P. andMurphy, J. R. 1980. EnterotoxigenicEscherichia coli carrying plasmids coding for antibiotic resistance and enterotoxin production. \u2014 J. Infect. Dis.142: 273\u2013278.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR10","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1017\/S0022172400026851","volume":"84","author":"C. H. Emmelot","year":"1980","unstructured":"Emmelot, C. H. andVan der Waaij, D. 1980. The dose at which neomycin and polymyxin B can be applied for selective decontamination of the digestive tract in mice. \u2014 J. Hyg.84: 331\u2013340.","journal-title":"J. Hyg."},{"key":"BF02386238_CR11","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1128\/iai.12.3.656-667.1975","volume":"12","author":"D. G. Evans","year":"1975","unstructured":"Evans, D. G., Silver, R. P., Evans, D. J., Chase, D. G. andGorbach, S. L. 1975. Plasmid-controlled colonization factor associated with virulence inEscherichia coli enterotoxin for humans. \u2014 Infect. Immun.12: 656\u2013667.","journal-title":"Infect. Immun."},{"key":"BF02386238_CR12","first-page":"659","volume":"1965","author":"S. M. Finegold","year":"1965","unstructured":"Finegold, S. M., Harada, N. E. andMiller, L. G. 1965. Lincomycin: activity against anaerobes and effect on normal human fecal flora. \u2014 Antimicrob. Agents Chemother.1965: 659\u2013667.","journal-title":"Antimicrob. Agents Chemother."},{"key":"BF02386238_CR13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/infdis\/110.1.38","volume":"110","author":"R. Freter","year":"1962","unstructured":"Freter, R. 1962. In vivo and in vitro antagonism of intestinal bacteria againstShigella flexneri. II. The inhibitory mechanism. \u2014 J. Infect. Dis.110: 38\u201346.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR14","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1128\/AAC.9.3.474","volume":"9","author":"W. Gaman","year":"1976","unstructured":"Gaman, W., Cates, C., Snelling, C. F. T., Lank, B. andRonald, A. R. 1976. Emergence of gentamicin- and carbenicillin-resistantPseudomonas aeruginosa in a hospital environment. \u2014 Antimicrob. Agents Chemother.9: 474\u2013480.","journal-title":"Antimicrob. Agents Chemother."},{"key":"BF02386238_CR15","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1093\/infdis\/120.3.298","volume":"120","author":"S. L. Gorbach","year":"1969","unstructured":"Gorbach, S. L., Spanknebel, G., Weinstein, L., Plant, A. G., Nahas, L. andLevitan, R. 1969. Studies of intestinal microflora. VIII. Effect of Lincomycin on the microbial population of the human intestine. \u2014 J. Infect. Dis.120: 298\u2013304.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR16","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1093\/infdis\/143.5.644","volume":"143","author":"H. F. L. Guiot","year":"1981","unstructured":"Guiot, H. F. L., Van der Meer, J. W. M. andVan Furth, R. 1981. Selective antimicrobial modulation of human microbial flora: infection prevention in patients with decreased host defense mechanisms by selective elimination of potentially pathogenic bacteria. \u2014 J. Infect. Dis.143: 644\u2013654.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR17","first-page":"249","volume-title":"Recent Advances in Germfree Research","author":"B. E. Gustafson","year":"1981","unstructured":"Gustafson, B. E., Carlstedt-Duke, B. andNord, C. E. 1981. Mucosa related intestinal bacteria and host metabolism. p. 249\u2013254.In S. Sasaki, A. Ozawa and K. Hashimoto (eds), Recent Advances in Germfree Research. \u2014 Tokai University Press, Tokyo."},{"key":"BF02386238_CR18","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1099\/00222615-11-2-125","volume":"11","author":"Ch. L. Hartley","year":"1977","unstructured":"Hartley, Ch. L., Clements, H. M. andLinton, K. B. 1977. Effects of cephalexin erythromycin and clindamycin on the aerobic gram-negative faecal flora in man. \u2014 J. Med. Microbiol.11: 125\u2013135.","journal-title":"J. Med. Microbiol."},{"key":"BF02386238_CR19","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1007\/BF01816741","volume":"10","author":"A. Heimdahl","year":"1982","unstructured":"Heimdahl, A., Kager, L., Malmborg, A. S. andNord, C. E. 1982. Impact of different betalactam antibiotics on the normal human flora, and colonization of the oral cavity, throat and colon. \u2014 Infection10: 120\u2013124.","journal-title":"Infection"},{"key":"BF02386238_CR20","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/BF02014139","volume":"1","author":"A. Heimdahl","year":"1982","unstructured":"Heimdahl, A. andNord, C. E. (1982). Effect of erythromycin and clindamycin on the indigenous human anaerobic flora and new colonization of the gastrointestinal tract. \u2014 Eur. J. Clin. Microbiol.1: 38\u201348.","journal-title":"Eur. J. Clin. Microbiol."},{"key":"BF02386238_CR21","first-page":"341","volume":"12","author":"N. A. Hinton","year":"1970","unstructured":"Hinton, N. A. 1970. The effect of oral tetracycline-HCl and doxycycline on the intestinal flora. \u2014 Curr. Ther. Res. Clin. Exp.12: 341\u2013352.","journal-title":"Curr. Ther. Res. Clin. Exp."},{"key":"BF02386238_CR22","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1365-2672.1974.tb00447.x","volume":"37","author":"D. C. Hirsh","year":"1974","unstructured":"Hirsh, D. C., Burton, G. C. andBlenden, D. C. 1974. The effect of tetracycline upon establishment ofEscherichia coli of bovine origin in the enteric tract of man. \u2014 J. Appl. Bacteriol.37: 327\u2013333.","journal-title":"J. Appl. Bacteriol."},{"key":"BF02386238_CR23","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1172\/JCI108270","volume":"57","author":"L. C. Hoskins","year":"1976","unstructured":"Hoskins, L. C. andBoulding, E. T. 1976a. Degradation of blood group antigens in human colon ecosystems. I. In vitro production of ABH blood group-degrading enzymes by enteric bacteria. \u2014 J. Clin. Invest.57: 63\u201373.","journal-title":"J. Clin. Invest."},{"key":"BF02386238_CR24","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1172\/JCI108271","volume":"57","author":"L. C. Hoskins","year":"1976","unstructured":"Hoskins, L. C. andBoulding, E. T. 1976b. Degradation of blood group antigens in human colon ecosystems. II. A gene interaction in man that affects the fecal population density of certain enteric bacteria. \u2014 J. Clin. Invest.57: 74\u201382.","journal-title":"J. Clin. Invest."},{"key":"BF02386238_CR25","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0016-5085(68)80005-8","volume":"54","author":"L. C. Hoskins","year":"1968","unstructured":"Hoskins, L. C. andZamchek, N. 1968. Bacterial degradation of gastrointestinal mucins. I. Comparison of mucus constituents in the stools of germ-free and conventional rats. \u2014 Gastroenterology54: 210\u2013217.","journal-title":"Gastroenterology"},{"key":"BF02386238_CR26","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1007\/BF01746196","volume":"59","author":"U. Jehn","year":"1981","unstructured":"Jehn, U., Ruckdeschell, G., Saner, H., Clemm, Ch. andWilmans, W. 1981. Vergleichende Studie zum Wert der selektiven Darmdekontamination (SDD) bei der Behandlung akuter Leuk\u00e4mien. \u2014 Klin. Wochenschr.59: 1093\u20131099.","journal-title":"Klin. Wochenschr."},{"key":"BF02386238_CR27","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1056\/NEJM196911202812101","volume":"281","author":"W. G. Johanson","year":"1969","unstructured":"Johanson, W. G., Pierce, A. K. andSanford, J. P. 1969. Changing pharyngeal bacterial flora of hospitalized patients: emergence of gram-negative bacilli. \u2014 N. Engl. J. Med.281: 1137\u20131140.","journal-title":"N. Engl. J. Med."},{"key":"BF02386238_CR28","doi-asserted-by":"crossref","first-page":"10","DOI":"10.7326\/0003-4819-22-1-10","volume":"22","author":"L. A. Julianelle","year":"1945","unstructured":"Julianelle, L. A. andSiegel, M. 1945. The epidemiology of acute respiratory infections conditioned by sulfonamides. II. Gross alterations in the nasopharyngeal flora associated with treatment. \u2014 Ann. Intern. Med.22: 10\u201320.","journal-title":"Ann. Intern. Med."},{"key":"BF02386238_CR29","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1007\/BF01746194","volume":"59","author":"E. Kurrle","year":"1981","unstructured":"Kurrle, E. 1981. Infektprophylaxe bei der Induktionstherapie akuter Leuk\u00e4mien. \u2014 Klin. Wochenschr.59: 1075\u20131079.","journal-title":"Klin. Wochenschr."},{"key":"BF02386238_CR30","first-page":"926","volume":"114","author":"F. M. LaForce","year":"1976","unstructured":"LaForce, F. M., Hopkins, J., Trow, R. andWang, W. L. L. 1976. Human oral defense against gram-negative rods. \u2014 Am. Rev. Respir. Dis.114: 926\u2013935.","journal-title":"Am. Rev. Respir. Dis."},{"key":"BF02386238_CR31","first-page":"74","volume-title":"New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance","author":"R. Laufs","year":"1979","unstructured":"Laufs, R., Fock, R., Von H\u00fclst, F. B. andRitter, R. 1979. Transfer of R-factors during antibiotic treatment in the hospital. p. 74\u201388.In D. van der Waaij and J. Verhoef (eds), New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance. \u2014 Excerpta Medica, Amsterdam."},{"key":"BF02386238_CR32","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/00000441-197905000-00005","volume":"227","author":"J. L. LeFrock","year":"1979","unstructured":"LeFrock, J. L., Ellis, Ch. A. andWeinstein, L. 1979. The relation between aerobic fecal and oropharyngeal microflora in hospital patients. \u2014 Am. J. Med. Sci.227: 275\u2013280.","journal-title":"Am. J. Med. Sci."},{"key":"BF02386238_CR33","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1084\/jem.121.2.201","volume":"121","author":"G. Lindstedt","year":"1965","unstructured":"Lindstedt, G., Lindstedt, S. andGustafson, B. E. 1965. Mucus intestinal contents of germfree rats. \u2014 J. Exp. Med.121: 201\u2013213.","journal-title":"J. Exp. Med."},{"key":"BF02386238_CR34","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1001\/jama.1963.03710110039008","volume":"186","author":"D. B. Louria","year":"1963","unstructured":"Louria, D. B. andBrayton, R. G. 1963. The efficacy of penicillin regimens: with observations on the frequency of superinfections. \u2014 J. Am. Med. Assoc.186: 937\u2013990.","journal-title":"J. Am. Med. Assoc."},{"key":"BF02386238_CR35","first-page":"649","volume":"85","author":"D. B. Louria","year":"1962","unstructured":"Louria, D. B. andKaminski, Th. 1962. The effects of four antimicrobial drug regimens on sputum superinfection in hospitalized patients. \u2014 Am. Rev. Respir. Dis.85: 649\u2013665.","journal-title":"Am. Rev. Respir. Dis."},{"key":"BF02386238_CR36","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1093\/ajcn\/25.12.1433","volume":"25","author":"B. R. Maier","year":"1972","unstructured":"Maier, B. R., Onderdonk, A. B., Baskett, R. C. andHentges, D. J. 1972.Shigella, indigenous flora interactions in mice. \u2014 Am. J. Clin. Nutr.25: 1433\u20131440.","journal-title":"Am. J. Clin. Nutr."},{"key":"BF02386238_CR37","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1080\/00039896.1961.10662870","volume":"2","author":"C. E. Meyers","year":"1961","unstructured":"Meyers, C. E., James, H. A. andZippin, C. 1961. The recovery of aerosolized bacteria from humans. I. Effects of varying exposure, sampling times, and subject variability. \u2014 Arch. Environ. Health2: 384\u2013388.","journal-title":"Arch. Environ. Health"},{"key":"BF02386238_CR38","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1056\/NEJM198201213060302","volume":"306","author":"B. E. Murray","year":"1982","unstructured":"Murray, B. E., Rensimer, E. R. andDuPont, H. L. 1982. Emergence of high-level trimethoprim resistance in fecalEscherichia coli during oral administration of trimethoprim or trimethoprimsulfamethoxazole. \u2014 N. Engl. J. Med.306: 130\u2013135.","journal-title":"N. Engl. J. Med."},{"key":"BF02386238_CR39","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1093\/infdis\/143.2.286","volume":"143","author":"H. G. Nandadasa","year":"1981","unstructured":"Nandadasa, H. G., Sargent, G. F., Brown, M. G. M., McNeish, A. S. andWilliams, P. H. 1981. The role of plasmids in adherence of adhesiveEscherichia coli to mammalian cells. \u2014 J. Infect. Dis.143: 286\u2013290.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR40","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/infdis\/114.3.235","volume":"114","author":"A. Ozawa","year":"1964","unstructured":"Ozawa, A. andFreter, R. 1964. Ecological mechanism controlling growth ofEscherichia coli in continuous flow cultures and in the mouse intestine. \u2014 J. Infect. Dis.114: 235\u2013242.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR41","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1128\/AAC.13.2.214","volume":"13","author":"N. J. Roberts Jr","year":"1978","unstructured":"Roberts, N. J. Jr andDouglas, R. G. Jr 1978. Gentamicin use andPseudomonas andSerratia resistance: effect of a surgical prophylaxis regimen. \u2014 Antimicrob. Agents Chemother.13: 214\u2013220.","journal-title":"Antimicrob. Agents Chemother."},{"key":"BF02386238_CR42","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1097\/00000441-196804000-00003","volume":"255","author":"H. D. Rose","year":"1968","unstructured":"Rose, H. D. andSchreier, J. 1968. The effect of hospitalization and antibiotic therapy on the gram-negative fecal flora. \u2014 Am. J. Med. Sci.255: 228\u2013236.","journal-title":"Am. J. Med. Sci."},{"key":"BF02386238_CR43","doi-asserted-by":"crossref","first-page":"355","DOI":"10.7326\/0003-4819-83-3-355","volume":"83","author":"S. Rosenthal","year":"1975","unstructured":"Rosenthal, S. andTager, I. B. 1975. Prevalence of gram-negative rods in the normal pharyngeal flora. \u2014 Ann. Intern. Med.83: 355\u2013357.","journal-title":"Ann. Intern. Med."},{"key":"BF02386238_CR44","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1146\/annurev.mi.31.100177.000543","volume":"31","author":"D. C. Savage","year":"1977","unstructured":"Savage, D. C. 1977. Microbial ecology of the gastrointestinal tract. \u2014 Annu. Rev. Microbiol.31: 107\u2013133.","journal-title":"Annu. Rev. Microbiol."},{"key":"BF02386238_CR45","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/ajcn\/32.1.113","volume":"32","author":"D. C. Savage","year":"1979","unstructured":"Savage, D. C. 1979. Introduction to mechanisms of association of indigenous microbes. \u2014 Am. J. Clin. Nutr.32: 113\u2013118.","journal-title":"Am. J. Clin. Nutr."},{"key":"BF02386238_CR46","doi-asserted-by":"crossref","first-page":"351","DOI":"10.7326\/0003-4819-82-3-351","volume":"82","author":"S. C. Schimpff","year":"1975","unstructured":"Schimpff, S. C., Greene, W. H., Young, V. M., Fortner, C. L., Jepsen, L., Cusack, N., Block, J. B. andWiernik, P. H. 1975. Infection prevention in acute non-lymphocytic leukemia. Laminar air flow rooms reverse isolation with oral, nonabsorbable antibiotic prophylaxis. \u2014 Ann. Intern. Med.82: 351\u2013358.","journal-title":"Ann. Intern. Med."},{"key":"BF02386238_CR47","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1017\/S0022172400046519","volume":"71","author":"E. J. Shaw","year":"1973","unstructured":"Shaw, E. J., Datta, N., Jones, G., Marr, F. M. andFroud, W. J. B. 1973. Effect of stay in hospital and oral chemotherapy on the antibiotic sensitivity of bowel coliforms. \u2014 J. Hyg.71: 529\u2013534.","journal-title":"J. Hyg."},{"key":"BF02386238_CR48","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0014-2964(80)90140-1","volume":"16","author":"D. T. Sleijfer","year":"1980","unstructured":"Sleijfer, D. T., Mulder, N. H., De Vries-Hospers, H. G., Fidler, V., Nieweg, H. O., Van der Waaij, D. andVan Saene, H. K. F. 1980. Infection prevention in granulocytopenic patients by selective decontamination of the digestive tract. \u2014 Eur. J. Cancer16: 859\u2013869.","journal-title":"Eur. J. Cancer"},{"key":"BF02386238_CR49","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.7326\/0003-4819-37-6-1135","volume":"37","author":"D. T. Smith","year":"1952","unstructured":"Smith, D. T. 1952. The disturbance of the normal bacterial ecology by the administration of antibiotics with the development of new clinical syndromes. \u2014 Ann. Intern. Med.37: 1135\u20131143.","journal-title":"Ann. Intern. Med."},{"key":"BF02386238_CR50","first-page":"471","volume":"18","author":"D. Sompolinski","year":"1967","unstructured":"Sompolinski, D., Yaron, V. andAlkan, W. J. 1967. Microbiological changes in the human fecal flora following the administration of tetracyclines and chloramphenicol. \u2014 Am. J. Proctol.18: 471\u2013478.","journal-title":"Am. J. Proctol."},{"key":"BF02386238_CR51","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0140-6736(73)93192-9","volume":"ii","author":"R. C. Spencer","year":"1973","unstructured":"Spencer, R. C. andPhilp, J. R. 1973. Effect of previous antimicrobial therapy on bacteriological findings in patients with primary pneumonia. \u2014 Lancetii: 349\u2013351.","journal-title":"Lancet"},{"key":"BF02386238_CR52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/infdis\/123.1.1","volume":"123","author":"K. Sprunt","year":"1971","unstructured":"Sprunt, K., Leidy, G. A. andRedman, W. 1971. Prevention of bacterial overgrowth. \u2014 J. Infect. Dis.123: 1\u201310.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR53","doi-asserted-by":"crossref","first-page":"579","DOI":"10.7326\/0003-4819-68-3-579","volume":"68","author":"K. Sprunt","year":"1968","unstructured":"Sprunt, K. andRedman, W. 1968. Evidence suggesting importance of role of interbacterial inhibition in maintaining balance of normal flora. \u2014 Ann. Intern. Med.68: 579\u2013590.","journal-title":"Ann. Intern. Med."},{"key":"BF02386238_CR54","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0140-6736(68)90068-8","volume":"i","author":"B. Stratford","year":"1968","unstructured":"Stratford, B., Gallus, A. S., Matthiesson, A. M. andDixson, S. 1968. Alteration of superficial bacterial flora in severely ill patients. \u2014 Lanceti: 68.","journal-title":"Lancet"},{"key":"BF02386238_CR55","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1017\/S0022172400053924","volume":"82","author":"H. A. Thijm","year":"1979","unstructured":"Thijm, H. A. andVan der Waaij, D. 1979. The effect of three frequently applied antibiotics on the colonization resistance of the digestive tract of mice. \u2014 J. Hyg.82: 397\u2013405.","journal-title":"J. Hyg."},{"key":"BF02386238_CR56","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1007\/BF00393669","volume":"49","author":"J. P. Van de Merwe","year":"1983","unstructured":"Van de Merwe, J. P., Stegeman, J. H. andHazenberg, M. P. 1983. The resident faecal flora is determined by genetic characteristics of the host. Implications for Crohn\u2019s disease? \u2014 Antonie van Leeuwenhoek49: 119\u2013124.","journal-title":"Antonie van Leeuwenhoek"},{"key":"BF02386238_CR57","first-page":"271","volume-title":"New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance","author":"D. Van der Waaij","year":"1979","unstructured":"Van der Waaij, D. 1979a. Colonization resistance of the digestive tract as a major lead in the selection of antibiotics for therapy. p. 271\u2013280.In D. van der Waaij and J. Verhoef (eds), New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance. \u2014 Excerpta Medica, Amsterdam."},{"key":"BF02386238_CR58","first-page":"43","volume-title":"New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance","author":"D. Van der Waaij","year":"1979","unstructured":"Van der Waaij, D. 1979b. The colonization resistance of the digestive tract in experimental animals and its consequences for infection prevention, acquisition of new bacteria and the prevention of spread of bacteria between cage mates. p. 43\u201352.In D. van der Waaij and J. Verhoef (eds), New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance. \u2014 Excerpta Medica, Amsterdam."},{"key":"BF02386238_CR59","first-page":"155","volume":"7","author":"D. Van der Waaij","year":"1979","unstructured":"Van der Waaij, D. 1979c. The colonization resistance of the digestive tract in man and animals. \u2014 Zentralbl. Bacteriol. Parasitenkd. Infektionskr. Hyg. Abt. 1 Suppl.7: 155\u2013161.","journal-title":"Zentralbl. Bacteriol. Parasitenkd. Infektionskr. Hyg. Abt. 1 Suppl."},{"key":"BF02386238_CR60","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/BF01640836","volume":"10","author":"D. Van der Waaij","year":"1982","unstructured":"Van der Waaij, D., Aberson, J., Thijm, H. A. andWelling, G. W. 1982. The screening of four aminoglycosides in the selective decontamination of the digestive tract in mice. \u2014 Infection10: 35\u201340.","journal-title":"Infection"},{"key":"BF02386238_CR61","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1017\/S002217240002341X","volume":"72","author":"D. Van der Waaij","year":"1974","unstructured":"Van der Waaij, D. andBerghuis-De Vries, J. M. 1974. Selective elimination of Enterobacteriaceae species from the digestive tract in mice and monkeys. \u2014 J. Hyg.72: 205\u2013211.","journal-title":"J. Hyg."},{"key":"BF02386238_CR62","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1017\/S0022172400022385","volume":"70","author":"D. Van der Waaij","year":"1972","unstructured":"Van der Waaij, D., Berghuis-De Vries, J. M. and Lekkerkerk-Van der Wees,J. E. C. 1972. Colonization resistance of the digestive tract and spread of bacteria to the lymphatic organs. \u2014 J. Hyg.70: 335\u2013342.","journal-title":"J. Hyg."},{"key":"BF02386238_CR63","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1017\/S0022172400021653","volume":"69","author":"D. Van der Waaij","year":"1971","unstructured":"Van der Waaij, D., De Vries, J. M. andLekkerkerk, J. E. C. 1971. Colonization resistance of the digestive tract in conventional and antibiotic-treated mice. \u2014 J. Hyg.69: 405\u2013411.","journal-title":"J. Hyg."},{"key":"BF02386238_CR64","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/infdis\/146.3.417","volume":"146","author":"D. Van der Waaij","year":"1982","unstructured":"Van der Waaij, D., Hofstra, W. andWiegersma, N. 1982. The effect of two cephalosporins and two broad-spectrum penicillins on the colonization resistance of the digestive tract. \u2014 J. Infect. Dis.146: 417\u2013422.","journal-title":"J. Infect. Dis."},{"key":"BF02386238_CR65","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1007\/BF01639756","volume":"5","author":"D. Van der Waaij","year":"1977","unstructured":"Van der Waaij, D., Tielemans-Speltie, T. M. andDe Roeck-Houben, A. M. J. 1977. Infection by and distribution of biotypes of Enterobacteriaceae species in leukaemic patients treated under ward conditions and in units for protective isolation in seven hospitals in Europe. \u2014 Infection5: 188\u2013194.","journal-title":"Infection"},{"key":"BF02386238_CR66","first-page":"197","volume-title":"New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance","author":"H. K. F. Van Saene","year":"1979","unstructured":"Van Saene, H. K. F. andDriessen, L. H. M. N. 1979. Importance of the treatment ofStaphylococcus aureus carriership in the prevention and therapy ofStaphylococcus aureus infections. p. 197\u2013205.In D. van der Waaij and J. Verhoef (eds), New Criteria for Antimicrobial Therapy: Maintenance of Digestive Tract Colonization Resistance. \u2014 Excerptia Medica, Amsterdam."},{"key":"BF02386238_CR67","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0140-6736(82)92554-5","volume":"i","author":"J. G. Watson","year":"1982","unstructured":"Watson, J. G., Powles, R. L., Lawson, D. N., Morgenstern, G. R., Jameson, B., McElwain, T. J., Judson, I., Lumley, H. andKay, H. E. M. 1982. Co-trimoxazole versus non-absorbable antibiotics in acute leukaemia. \u2014 Lanceti: 6\u20139.","journal-title":"Lancet"},{"key":"BF02386238_CR68","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/00000441-194707000-00008","volume":"214","author":"L. Weinstein","year":"1947","unstructured":"Weinstein, L. 1947. The spontaneous occurrence of new bacterial infections during the course of treatment with streptomycin or penicillin. \u2014 Am. J. Med. Sci.214: 56\u201363.","journal-title":"Am. J. Med. Sci."},{"key":"BF02386238_CR69","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1017\/S0022172400070091","volume":"88","author":"N. Wiegersma","year":"1982","unstructured":"Wiegersma, N., Jansen, G. andVan der Waaij, D. 1982. Effect of twelve antimicrobial drugs on the colonization resistance of the digestive tract of mice and on endogenous potentially pathogenic bacteria. \u2014 J. Hyg.88: 221\u2013230.","journal-title":"J. Hyg."},{"key":"BF02386238_CR70","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1056\/NEJM198201073060105","volume":"306","author":"J. M. Wilson","year":"1982","unstructured":"Wilson, J. M. andGuiney, D. G. 1982. Failure of oral trimethoprim-sulfamethoxazole prophylaxis in acute leukemia. Isolation of resistant plasmids from strains of Enterobacteriaceae causing bacteremia. \u2014 N. Engl. J. Med.306: 16\u201320.","journal-title":"N. Engl. J. Med."}],"container-title":["Antonie van Leeuwenhoek"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02386238.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF02386238\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02386238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02386238.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,14]],"date-time":"2022-05-14T18:01:09Z","timestamp":1652551269000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF02386238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,11]]},"references-count":70,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[1984,11]]}},"alternative-id":["BF02386238"],"URL":"https:\/\/doi.org\/10.1007\/bf02386238","relation":{},"ISSN":["0003-6072","1572-9699"],"issn-type":[{"value":"0003-6072","type":"print"},{"value":"1572-9699","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,11]]}}}