{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T06:06:01Z","timestamp":1778306761005,"version":"3.51.4"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1996,3,1]],"date-time":"1996-03-01T00:00:00Z","timestamp":825638400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Gastroenterol"],"published-print":{"date-parts":[[1996,3]]},"DOI":"10.1007\/bf02389520","type":"journal-article","created":{"date-parts":[[2006,4,10]],"date-time":"2006-04-10T10:26:31Z","timestamp":1144664791000},"page":"214-223","source":"Crossref","is-referenced-by-count":4,"title":["Distribution of nitric oxide synthase-containing nerves in the aganglionic intestine of mutant rats: A histochemical study"],"prefix":"10.1007","volume":"31","author":[{"given":"Makoto","family":"Teramoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokio","family":"Domoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichiro","family":"Tanigawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiko","family":"Yasui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiro","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02389520_CR1","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1399-0004.1985.tb00417.x","volume":"28","author":"KL Garver","year":"1985","unstructured":"Garver KL, Law CJ, Garver B. Hirschsprung's disease: A genetic study. Clin Genet 1985;28:503\u2013508.","journal-title":"Clin Genet"},{"key":"BF02389520_CR2","first-page":"615","volume":"9","author":"LT Larsson","year":"1994","unstructured":"Larsson LT. Hirschsprung's disease\u2014immunohistochemical findings. Histol Histopathol 1994;9:615\u2013629.","journal-title":"Histol Histopathol"},{"key":"BF02389520_CR3","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1111\/j.1365-2559.1981.tb01834.x","volume":"5","author":"AE Bishop","year":"1981","unstructured":"Bishop AE, Polak JM, Lake BD, et al. Abnormalities of the colonic regulatory peptides in Hirschspring's disease. Histopathology 1981;5:679\u2013699.","journal-title":"Histopathology"},{"key":"BF02389520_CR4","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF00692647","volume":"401","author":"T Taguchi","year":"1983","unstructured":"Taguchi T, Tanaka K, Ikeda K, et al. Peptidergic innervation irregularities in Hirschsprung's disease. Virchows Arch [A] 1983;401:223\u2013235.","journal-title":"Virchows Arch [A]"},{"key":"BF02389520_CR5","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/0022-3468(91)90336-R","volume":"26","author":"LT Larsson","year":"1991","unstructured":"Larsson LT, Malmfors G, Ekblad E, et al. NPY hyperinnervation in Hirschsprung's disease: Both adrenergic and nonadrenergic fibers contribute. Pediatr Surg 1991;26:1207\u20131214.","journal-title":"Pediatr Surg"},{"key":"BF02389520_CR6","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/0306-4522(84)90022-8","volume":"12","author":"TP Rothman","year":"1984","unstructured":"Rothman TP, Gershon MD. Regionally defective colonization of the terminal bowel by the precursors of enteric neurons in lethal spotted mutant mice. Neuroscience 1984;12:1293\u20131311.","journal-title":"Neuroscience"},{"key":"BF02389520_CR7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0016-5085(82)90018-X","volume":"82","author":"C Vaillant","year":"1982","unstructured":"Vaillant C, Bu'lock A, Dimaline R, et al. Distribution and development of peptidergic nerves and gut endocrine cells in mice with congenital aganglionic colon, and their normal littermates. Gastroenterology 1982;82:291\u2013300.","journal-title":"Gastroenterology"},{"key":"BF02389520_CR8","first-page":"573","volume":"30","author":"W Webster","year":"1973","unstructured":"Webster W. Embryogenesis of the enteric ganglia in normal mice and in mice that develop congenital aganglionic megacolon. J Embryol Exp Morphol 1973;30:573\u2013585.","journal-title":"J Embryol Exp Morphol"},{"key":"BF02389520_CR9","first-page":"549","volume":"16","author":"H Horie","year":"1980","unstructured":"Horie H, Ikadai H, Iwasaki I, et al. Pathologic studies on newly established congenital aganglionosis rat in Japan (in Japanese with English abstract). J Jpn Soc Ped Surg 1980;16:549\u2013560.","journal-title":"J Jpn Soc Ped Surg"},{"key":"BF02389520_CR10","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0168-0102(87)90047-2","volume":"4","author":"T Domoto","year":"1987","unstructured":"Domoto T, Oki M, Gonda T, et al. Distribution of neves containing vasoactive intestinal polypeptide-like immunoreactivity in rats with congenital aganglionosis of the colon. Neurosci Res 1987;4:309\u2013315.","journal-title":"Neurosci Res"},{"key":"BF02389520_CR11","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1538\/expanim1978.40.4_471","volume":"40","author":"T Gonda","year":"1991","unstructured":"Gonda T, Oki M. Distribution of cholinergic and catecholaminergic nerves in the colon of the rat with aganglionosis. Exp Anim 1991;40:471\u2013484.","journal-title":"Exp Anim"},{"key":"BF02389520_CR12","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/0168-0102(92)90018-8","volume":"15","author":"T Domoto","year":"1992","unstructured":"Domoto T, Yang H, Bishop AE, et al. Distribution and origin of extrinsic nerve fibers containing calcitonin gene-related peptide, substance P and galanin in the rat upper rectum. Neurosci Res 1992;15:64\u201373.","journal-title":"Neurosci Res"},{"issue":"1","key":"BF02389520_CR13","first-page":"65","volume":"3","author":"T Domoto","year":"1992","unstructured":"Domoto T, Gonda T, Oki M. Distribution of extrinsic nerves containing vasoactive intestinal polypeptide-like immunoreactivity in the aganglionic bowel of the congenital aganglionosis rats. Biomed Res (India) 1992;3(1):65\u201377.","journal-title":"Biomed Res (India)"},{"key":"BF02389520_CR14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF00208195","volume":"187","author":"R Hirose","year":"1993","unstructured":"Hirose R, Nada O, Kawana T, et al. The intramural pelvic nerves immunoreactive for calcitonin gene-related peptide in the rectum of normal and aganglionosis rat. Anat Embryol 1993;187:37\u201344.","journal-title":"Anat Embryol"},{"key":"BF02389520_CR15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0165-1838(94)90133-3","volume":"49","author":"T Domoto","year":"1994","unstructured":"Domoto T, Zhang WB, Tsumori T, et al. Distribution of extrinsic enkephalin-containing nerve fibers in the rat rectum and their origin in the major pelvic ganglion. J Auton Nerv Syst 1994;49:135\u2013146.","journal-title":"J Auton Nerv Syst"},{"key":"BF02389520_CR16","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/0016-5085(93)90938-9","volume":"105","author":"JM Vanderwinden","year":"1993","unstructured":"Vanderwinden JM, De Laet MH, Schiffmann SN, et al. Nitric oxide synthase distribution in the enteric nervous system of Hirschpsprung's disease. Gastroenterology 1993;105:969\u2013973.","journal-title":"Gastroenterology"},{"key":"BF02389520_CR17","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/0022-3468(93)90166-I","volume":"28","author":"C Cuffari","year":"1993","unstructured":"Cuffari C, Rubin SZ, Krantis A. Routine use of the nitric oxide stain in the differential diagnosis of Hirschsprung's disease. J Pediatr Surg 1993;28:1202\u20131204.","journal-title":"J Pediatr Surg"},{"key":"BF02389520_CR18","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/333664a0","volume":"333","author":"RMJ Palmer","year":"1988","unstructured":"Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide froml-arginine. Nature 1988;333:664\u2013666.","journal-title":"Nature"},{"key":"BF02389520_CR19","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0166-2236(92)90029-8","volume":"15","author":"JB Furness","year":"1992","unstructured":"Furness JB, Bornstein JC, Murphy R, et al. Roles of peptides in transmission in the enteric nervous system. Trends Neurosci 1992;15:66\u201371.","journal-title":"Trends Neurosci"},{"key":"BF02389520_CR20","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1016\/0016-5085(92)91454-C","volume":"103","author":"ME Stark","year":"1992","unstructured":"Stark ME, Szurszewski JH. Role of nitric oxide in gastrointestinal and hepatic function and disease. Gastroenterology 1992;103:1928\u20131949.","journal-title":"Gastroenterology"},{"key":"BF02389520_CR21","first-page":"31","volume":"19","author":"H Ikadai","year":"1979","unstructured":"Ikadai H, Fujita H, Agematsu Y, et al. Observation of congenital aganglionosis rat (Hirschsprung's disease rat) and its genetical analysis (in Japanese with English abstract). Cong Anom 1979; 19:31\u201336.","journal-title":"Cong Anom"},{"key":"BF02389520_CR22","doi-asserted-by":"crossref","first-page":"7797","DOI":"10.1073\/pnas.88.17.7797","volume":"88","author":"TM Dawson","year":"1991","unstructured":"Dawson TM, Bredt DS, Fotuhi M, et al. Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci USA 1991;88:7797\u20137801.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF02389520_CR23","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/0304-3940(92)90233-W","volume":"143","author":"A Belai","year":"1992","unstructured":"Belai A, Schmidt HHHW, Hoyle CHV, et al. Colocalization of nitric oxide synthase and NADPH-diaphorase in the myenteric plexus of the rat gut. Neurosci Lett 1992;143:60\u201364.","journal-title":"Neurosci Lett"},{"key":"BF02389520_CR24","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/BF02913739","volume":"271","author":"K McConalogue","year":"1993","unstructured":"McConalogue K, Furness JB. Projections of nitric oxide synthesizing neurons in the guinea-pig colon. Cell Tissue Res 1993;271:545\u2013553.","journal-title":"Cell Tissue Res"},{"key":"BF02389520_CR25","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0306-4522(93)90220-A","volume":"53","author":"Y Aimi","year":"1993","unstructured":"Aimi Y, Kimura H, Kinoshita T, et al. Histochemical localization of nitric oxide synthase in rat enteric nervous system. Neuroscience 1993;53:553\u2013560.","journal-title":"Neuroscience"},{"key":"BF02389520_CR26","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/0016-5085(93)91060-U","volume":"105","author":"K Nichols","year":"1993","unstructured":"Nichols K, Staines W, Krantis A. Nitric oxide synthase distribution in the rat intestine: A histochemical analysis. Gastroenterology 1993;105:1651\u20131661.","journal-title":"Gastroenterology"},{"key":"BF02389520_CR27","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/ar.1092150310","volume":"215","author":"VM Tennyson","year":"1986","unstructured":"Tennyson VM, Pham TD, Rothman TP, et al. Abnormalities of smooth muscle, basal laminae, and nerves in the aganglionic segments of the bowel of lethal spotted mutant mice. Anat Rec 1986;215:267\u2013281.","journal-title":"Anat Rec"},{"key":"BF02389520_CR28","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1002\/cne.902570209","volume":"257","author":"RF Payette","year":"1987","unstructured":"Payette RF, Tennyson VM, Pham TD, et al. Origin and morphology of nerve fibers in the aganglionic colon of the lethal spotted (Is\/Is) mutant mouse. J Comp Neurol 1987;257:237\u2013252.","journal-title":"J Comp Neurol"},{"key":"BF02389520_CR29","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/0016-5085(92)90761-M","volume":"102","author":"DH Parikh","year":"1992","unstructured":"Parikh DH, Tam PKH, Velzen DV, et al. Abnormalities in the distribution of laminin and collagen type IV in Hirschsprung's disease. Gastroenterology 1992;102:1236\u20131241.","journal-title":"Gastroenterology"},{"key":"BF02389520_CR30","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/0006-291X(90)91605-R","volume":"172","author":"F Hata","year":"1990","unstructured":"Hata F, Ishii T, Kanada A, et al. Essential role of nitric oxide in descending inhibition in the rat proximal colon. Biochem Biophys Res Commun 1990;172:1400\u20131406.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF02389520_CR31","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0304-3940(92)90819-S","volume":"148","author":"M Costa","year":"1992","unstructured":"Costa M, Furness JB, Pompolo S, et al. Projections and chemical conding of neurons with immunoreactivity for nitric oxide synthase in the guinea pig small intestine. Neurosci Lett 1992;148:121\u2013125.","journal-title":"Neurosci Lett"},{"key":"BF02389520_CR32","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/cne.903060303","volume":"306","author":"Y Aimi","year":"1991","unstructured":"Aimi Y, Fujimura M, Vincent SR, et al. Localization of NADPH-diaphorase-containing neurons in sensory ganglia of the rat. J Comp Neurol 1991;306:382\u2013392.","journal-title":"J Comp Neurol"},{"key":"BF02389520_CR33","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0022-3468(67)80085-X","volume":"2","author":"E Okamoto","year":"1967","unstructured":"Okamoto E, Ueda T. Embryogenesis of intramural ganglia of the gut and its relation to Hirschsprung's disease. J Pediat Surg 1967;2:437\u2013443.","journal-title":"J Pediat Surg"},{"key":"BF02389520_CR34","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/0006-8993(78)91088-0","volume":"151","author":"H Satomi","year":"1978","unstructured":"Satomi H, Yamamoto T, Ise H, et al. Origin of the parasympathetic preganglionic fibers to the cat intestine as demonstrated by the horseradish peroxidase method. Brain Res 1978;151:571\u2013578.","journal-title":"Brain Res"},{"key":"BF02389520_CR35","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/S0016-5085(84)80120-1","volume":"86","author":"J Christensen","year":"1984","unstructured":"Christensen J, Stiles MJ, Rick GA, et al. Comparative anatomy of the myenteric plexus of the distal colon in eight mammals. Gastroenterology 1984;86:706\u2013713.","journal-title":"Gastroenterology"},{"key":"BF02389520_CR36","first-page":"65","volume":"84","author":"W Stach","year":"1971","unstructured":"Stach W. Uber die in der Dickdarmwand aszendiereden Nerven des Plexus pelvinus und die Grenze der vagalen und sakralparasympathischem Innervation. Z Mikrosk Anat Forsch 1971;84:65\u201390.","journal-title":"Z Mikrosk Anat Forsch"},{"key":"BF02389520_CR37","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF00297549","volume":"271","author":"RM Santer","year":"1993","unstructured":"Santer RM, Symons D. Distribution of NADPH-diaphorase activity in rat paravertebral, prevertebral and pelvic sympathetic ganglia. Cell Tissue Res 1993;271:115\u2013121.","journal-title":"Cell Tissue Res"},{"key":"BF02389520_CR38","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/BF00414170","volume":"278","author":"T Domoto","year":"1994","unstructured":"Domoto T, Tsumori T. Co-localization of nitric oxide synthase and vasoactive intestinal peptide immunoreactivity in neurons of the major pelvic ganglion projecting to the rat rectum and penis. Cell Tissue Res 1994;278:273\u2013278.","journal-title":"Cell Tissue Res"}],"container-title":["Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02389520.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02389520\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02389520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T18:37:06Z","timestamp":1586803026000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02389520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,3]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,3]]}},"alternative-id":["BF02389520"],"URL":"https:\/\/doi.org\/10.1007\/bf02389520","relation":{},"ISSN":["0944-1174","1435-5922"],"issn-type":[{"value":"0944-1174","type":"print"},{"value":"1435-5922","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,3]]}}}