{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:35:48Z","timestamp":1793172948199,"version":"4.5.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1980,3,1]],"date-time":"1980-03-01T00:00:00Z","timestamp":320716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Autism Dev Disord"],"published-print":{"date-parts":[[1980,3]]},"DOI":"10.1007\/bf02408428","type":"journal-article","created":{"date-parts":[[2006,5,12]],"date-time":"2006-05-12T05:27:33Z","timestamp":1147411653000},"page":"1-14","source":"Crossref","is-referenced-by-count":22,"title":["Serum dopamine-beta-hydroxylase activity: Clinical applications in child psychiatry"],"prefix":"10.1007","volume":"10","author":[{"given":"J. G.","family":"Young","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Kyprie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. T.","family":"Ross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02408428_CR1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF01539632","volume":"8","author":"R. H. Belmaker","year":"1978","unstructured":"Belmaker, R. H., Hattab, J., & Ebstein, R. P. Plasma dopamine-\u03b2-hydroxylase in childhood psychosis.Journal of Autism and Childhood Schizophrenia, 1978,8, 293\u2013298.","journal-title":"Journal of Autism and Childhood Schizophrenia"},{"key":"BF02408428_CR2","first-page":"163","volume":"45","author":"N. J. Christianson","year":"1973","unstructured":"Christianson, N. J. Plasma noradrenaline and adrenaline in patients with thyrotoxicosis and myxodema.Clinical Science and Molecular Medicine, 1973,45, 163\u2013171.","journal-title":"Clinical Science and Molecular Medicine"},{"key":"BF02408428_CR3","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1001\/archpsyc.1974.01760180085011","volume":"31","author":"D. J. Cohen","year":"1974","unstructured":"Cohen, D. J., Shaywitz, B. A., Johnson, W. T., & Bowers, M. B., Jr. Biogenic amines in autistic and atypical children.Archives of General Psychiatry 1974,31, 845\u2013853.","journal-title":"Archives of General Psychiatry"},{"key":"BF02408428_CR4","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0002-7138(09)61596-X","volume":"16","author":"D. J. Cohen","year":"1977","unstructured":"Cohen, D. J., & Young, J. G. Neurochemistry and child psychiatry.Journal of the American Academy of Child Psychiatry, 1977,16, 353\u2013411.","journal-title":"Journal of the American Academy of Child Psychiatry"},{"key":"BF02408428_CR5","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1399-0004.1974.tb01699.x","volume":"5","author":"M. Coleman","year":"1974","unstructured":"Coleman, M., Campbell, M., Freedman, L. S., Roffman, M., Ebstein, R. P., & Goldstein, M. Serum dopamine-beta-hydroxylase levels in Down's syndrome.Clinical Genetics, 1974,5, 312\u2013315.","journal-title":"Clinical Genetics"},{"key":"BF02408428_CR6","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1212\/WNL.24.7.684","volume":"24","author":"R. P. Ebstein","year":"1974","unstructured":"Ebstein, R. P., Freedman, L. S., Lieberman, A., Park, D. H., Pasternack, B., Goldstein, M., & Coleman, M. A familial study of serum dopamine-\u03b2-hydroxylase levels in torsion dystonia.Neurology, 1974,24, 684\u2013687.","journal-title":"Neurology"},{"key":"BF02408428_CR7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/236310a0","volume":"236","author":"L. S. Freedman","year":"1972","unstructured":"Freedman, L. S., Ohuchi, T., Goldstein, M., Axelrod, F., Fish, I., & Dancis, J. Changes in human serum dopamine-\u03b2-hydroxylase activity with age.Nature, 1972,236, 310\u2013311.","journal-title":"Nature"},{"key":"BF02408428_CR8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1471-4159.1976.tb04434.x","volume":"26","author":"D. J. Goldstein","year":"1976","unstructured":"Goldstein, D. J., & Cubeddu, L. Dopamine-beta-hydroxylase activity in human cerebrospinal fluid.Journal of Neurochemistry, 1976,26, 193\u2013195.","journal-title":"Journal of Neurochemistry"},{"key":"BF02408428_CR9","first-page":"57","volume-title":"The autistic syndromes","author":"M. Goldstein","year":"1976","unstructured":"Goldstein, M. Dopamine-beta-hydroxylase and endogenous total 5-hydroxyindole levels in autistic patients and controls. In M. Coleman (Ed.),The autistic syndromes. New York: North-Holland, 1976. Pp. 57\u201358."},{"key":"BF02408428_CR10","volume-title":"Neuropsychopharmacology of monoamines and their regulatory systems","author":"M. Goldstein","year":"1974","unstructured":"Goldstein, M., Freedman, L. S., Ebstein, R. P., Park, D. H., & Kashimoto, T. Human serum dopamine-beta-hydroxylase: Relationship to sympathetic activity and physiological and pathological states. In E. Usdin (Ed.),Neuropsychopharmacology of monoamines and their regulatory systems. New York: Raven Press, 1974."},{"key":"BF02408428_CR11","first-page":"303","volume-title":"Advances in neurology","author":"W. Kanter","year":"1976","unstructured":"Kanter, W., Wooten, G. F., & Eldridge, R. Dopamine-\u03b2-hydroxylase and the torsion dysstonias. In R. Eldrige (Ed.),Advances in neurology (Vol. 14). New York: Raven Press, 1976. Pp. 303\u2013305."},{"key":"BF02408428_CR12","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF01244729","volume":"33","author":"H. L. Klawans","year":"1972","unstructured":"Klawans, H. L., & Shenker, D. M. Observations on the dopaminergic nature of hyperthyroid chorea.Journal of Neural Transmission, 1972,33, 73\u201381.","journal-title":"Journal of Neural Transmission"},{"key":"BF02408428_CR13","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/0006-2952(75)90172-0","volume":"24","author":"P. Laduron","year":"1975","unstructured":"Laduron, P. Scope and limitation in dopamine-beta-hydroxylase measurement.Biochemistry and Pharmacology, 1975,24, 557\u2013562.","journal-title":"Biochemistry and Pharmacology"},{"key":"BF02408428_CR14","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1001\/archpsyc.1977.01770170063005","volume":"34","author":"C. R. Lake","year":"1977","unstructured":"Lake, C. R., Ziegler, M. G., & Murphy, D. L. Increased norepinephrine levels and decreased dopamine-\u03b2-hydroxylase activity in primary autism.Archives of General Psychiatry, 1977,34, 553\u2013556.","journal-title":"Archives of General Psychiatry"},{"key":"BF02408428_CR15","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1210\/endo-92-3-953","volume":"92","author":"F. Lamprecht","year":"1973","unstructured":"Lamprecht, F., Williams, R. B., & Kopin, I. J. Serum dopamine-beta-hydroxylase during development of immobilization-induced hypertension.Endocrinology, 1973,92, 953\u2013956.","journal-title":"Endocrinology"},{"key":"BF02408428_CR16","volume-title":"Frontiers in catecholamine research","author":"F. Lamprecht","year":"1973","unstructured":"Lamprecht, F., Wyatt, R. J., Belmaker, R., Murphy, D. L., & Pollin, W. Plasma dopamine-beta-hydroxylase in identical twins discordant for schizophrenia. In E. Usdin & S. H. Snyder (Eds.),Frontiers in catecholamine research. New York: Pergamon Press, 1973."},{"key":"BF02408428_CR17","unstructured":"Leckman, J. F., Cohen, D. J., Shaywitz, B. A., Caparulo, B. K., Heninger, G. R., & Bowers, M. B., Jr. Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) in the cerebrospinal fluid of childhood and adult psychiatric patients: A developmental perspective.Archives of General Psychiatry, 1980, in press."},{"key":"BF02408428_CR18","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1001\/archpsyc.1976.01770050047007","volume":"33","author":"H. Y. Meltzer","year":"1976","unstructured":"Meltzer, H. Y., Cho, H. W., Carroll, B. J., & Russo, P. Serum dopamine-\u03b2-hydroxylase activity in the affective psychoses and schizophrenia.Archives of General Psychiatry, 1976,33, 585\u2013591.","journal-title":"Archives of General Psychiatry"},{"key":"BF02408428_CR19","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/clinchem\/18.9.980","volume":"18","author":"T. Nagatsu","year":"1972","unstructured":"Nagatsu, T., & Udenfriend, S. Photometric assay of dopamine-\u03b2-hydroxylase activity in human blood.Clinical Chemistry, 1972,18, 980\u2013983.","journal-title":"Clinical Chemistry"},{"key":"BF02408428_CR20","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1210\/jcem-39-3-599","volume":"39","author":"Y. Nishizawa","year":"1974","unstructured":"Nishizawa, Y., Hamada, N., Fujii, S., Morii, H., Okuda, K., & Wada, M. Serum dopamine-\u03b2-hydroxylase activity in thyroid disorders.Journal of Clinical Endocrinology and Metabolism, 1974,39, 599\u2013601.","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"BF02408428_CR21","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1161\/01.RES.38.6.2","volume":"38","author":"R. H. Noth","year":"1976","unstructured":"Noth, R. H., & Mulrow, P. J. Serum dopamine-beta-hydroxylase as an index of sympathetic nervous system activity in man.Circulation Research, 1976,38, 2\u20135.","journal-title":"Circulation Research"},{"key":"BF02408428_CR22","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1210\/jcem-39-3-614","volume":"39","author":"R. H. Noth","year":"1974","unstructured":"Noth, R. H., & Spaulding, S. W. Decreased serum dopamine-\u03b2-hydroxylase in hyperthyroidism.Journal of Clinical Endocrinology and Metabolism, 1974,39, 614\u2013617.","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"BF02408428_CR23","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF00567014","volume":"5","author":"G. Planz","year":"1973","unstructured":"Planz, G., & Palm, D. Acute enchancement of dopamine-\u03b2-hydroxylase activity in human plasma after maximum work load.European Journal of Clinical Pharmacology, 1973,5, 255\u2013258.","journal-title":"European Journal of Clinical Pharmacology"},{"key":"BF02408428_CR24","doi-asserted-by":"crossref","first-page":"4392","DOI":"10.1073\/pnas.71.11.4392","volume":"71","author":"J. L. Reid","year":"1974","unstructured":"Reid, J. L., & Kopin, I. J. Significance of plasma dopamine-beta-hydroxylase activity as an index of sympathetic neuronal function.Proceedings of the National Academy of Sciences, USA, 1974,71, 4392\u20134394.","journal-title":"Proceedings of the National Academy of Sciences, USA"},{"key":"BF02408428_CR25","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0024-3205(73)90056-8","volume":"12","author":"S. B. Ross","year":"1973","unstructured":"Ross, S. B., Wetterberg, L., & Myrhed, M. Genetic control of plasma dopamine-\u03b2-hydroxylase.Life Sciences, 1973,12, 529\u2013532.","journal-title":"Life Sciences"},{"key":"BF02408428_CR26","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1161\/01.RES.31.3.444","volume":"31","author":"R. A. Rush","year":"1972","unstructured":"Rush, R. A., & Geffen, L. B. Radioimmunoassay and clearance of circulatory dopamine-\u03b2-hydroxylase.Circulation Research, 1972,31, 444\u2013447.","journal-title":"Circulation Research"},{"key":"BF02408428_CR27","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/0006-2952(76)90233-1","volume":"25","author":"S. M. Schanberg","year":"1976","unstructured":"Schanberg, S. M., & Kirshner, N. Serum dopamine-\u03b2-hydroxylase as an indicator of sympathetic activity and primary hypertension.Biochemical Pharmacology, 1976,25, 617\u2013621.","journal-title":"Biochemical Pharmacology"},{"key":"BF02408428_CR28","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0009-8981(72)90226-4","volume":"38","author":"H. Seligson","year":"1972","unstructured":"Seligson, H., & Seligson, D. Measurement of thyroxine by competitive protein binding.Clinica Chimica Acta, 1972,38, 199\u2013204.","journal-title":"Clinica Chimica Acta"},{"key":"BF02408428_CR29","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1210\/jcem-36-3-587","volume":"36","author":"S. S. Stoffer","year":"1973","unstructured":"Stoffer, S. S., Jiang, N. S., Gorman, C. A., & Pikler, G. M. Plasma catecholamines in hypothyroidism and hyperthyroidism.Journal of Clinical Endocrinology and Metabolism, 1973,36, 587\u2013589.","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"BF02408428_CR30","unstructured":"The Task Force on Nomenclature and Statistics of the American Psychiatric Association.Diagnostic and statistical manual of mental disorders (3rd ed.). New York, authors, 1978."},{"key":"BF02408428_CR31","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1161\/01.RES.28.3.307","volume":"28","author":"R. Weinshilboum","year":"1971","unstructured":"Weinshilboum, R., & Axelrod, J. Serum dopamine-beta-hydroxylase activity.Circulation-Research, 1971,28, 307\u2013315. (a)","journal-title":"Circulation-Research"},{"key":"BF02408428_CR32","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1126\/science.173.4000.931","volume":"197","author":"R. Weinshilboum","year":"1971","unstructured":"Weinshilboum, R., & Axelrod, J. Serum dopamine-beta-hydroxylase: Decrease after chemical sympathectomy.Science, 1971,197, 931\u2013934. (b)","journal-title":"Science"},{"key":"BF02408428_CR33","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/B978-0-08-020588-5.50044-8","volume-title":"Catecholamines and stress","author":"R. M. Weinshilboum","year":"1976","unstructured":"Weinshilboum, R. M., Dunnette, J. H., Raymond, F. A., & Schrott, H. G. Genetic control of human serum dopamine-\u03b2-hydroxylase. In E. Usdin, R. Kvetnansky, & I. J. Kopin (Eds.),Catecholamines and stress. New York: Pergamon Press, 1976. Pp. 293\u2013303."},{"key":"BF02408428_CR34","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1126\/science.174.4016.1349","volume":"174","author":"R. M. Weinshilboum","year":"1971","unstructured":"Weinshilboum, R. M., Nguyen, B. T., Johnson, D. G., Kopin, I. J., & Axelrod, J. Proportional release of norepinephrine and dopamine-\u03b2-hydroxylase from sympathetic nerves.Science, 1971,174, 1349\u20131351.","journal-title":"Science"},{"key":"BF02408428_CR35","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1126\/science.181.4103.943","volume":"181","author":"R. M. Weinshilboum","year":"1973","unstructured":"Weinshilboum, R. M., Raymond, F. A., Elveback, L. R., & Weidman, W. H. Serum dopamine-beta-hydroxylase activity: Sibling-sibling correlation.Science, 1973,181, 943\u2013945.","journal-title":"Science"},{"key":"BF02408428_CR36","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1001\/archneur.1973.00490200051006","volume":"28","author":"F. G. Wooten","year":"1973","unstructured":"Wooten, F. G., & Cardon, P. V. Plasma dopamine-beta-hydroxylase activity: Elevation in man during cold pressor test and exercise.Archives of Neurology, 1973,28, 103\u2013106.","journal-title":"Archives of Neurology"},{"key":"BF02408428_CR37","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1056\/NEJM197302082880604","volume":"28","author":"G. F. Wooten","year":"1973","unstructured":"Wooten, G. F., Eidridge, R., Axelrod, J., & Stern, R. S. Elevated plasma dopamine-\u03b2-hydroxylase activity in autosomal dominant torsion dystonia.New England Journal of Medicine, 1973,28, 284\u2013287.","journal-title":"New England Journal of Medicine"},{"key":"BF02408428_CR38","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1176\/ajp.1979.136.4a.377","volume":"136","author":"R. J. Wyatt","year":"1979","unstructured":"Wyatt, R. J., Potkin, S. G., & Murphy, D. L. Platelet monoamine oxidase activity in schizophrenia: A review of the data.American Journal of Psychiatry, 1979,136, 377\u2013385.","journal-title":"American Journal of Psychiatry"},{"key":"BF02408428_CR39","first-page":"22","volume-title":"Basic handbook of child psychiatry","author":"J. G. Young","year":"1979","unstructured":"Young, J. G., & Cohen, D. J. The molecular biology of development. In J. Nospitz (Ed.),Basic handbook of child psychiatry (Vol. 1). New York: Basic Books, 1979. Pp. 22\u201362."},{"key":"BF02408428_CR40","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0002-7138(09)61019-0","volume":"17","author":"J. G. Young","year":"1978","unstructured":"Young, J. G., Cohen, D. J., Brown, S.-L., & Caparulo, B. K. Decreased urinary free catecholamines in childhood autism.Journal of the American Academy of Child Psychiatry, 1978,17, 671\u2013678.","journal-title":"Journal of the American Academy of Child Psychiatry"},{"key":"BF02408428_CR41","first-page":"1055","volume":"236","author":"J. G. Young","year":"1979","unstructured":"Young, J. G., Cohen, D. J., Caparulo, B. K., Brown, S.-L., & Maas, J. W. Decreased 24-hour urinary MHPG in childhood autism.American Journal of Psychiatry, 1979,236, 1055\u20131057.","journal-title":"American Journal of Psychiatry"},{"key":"BF02408428_CR42","doi-asserted-by":"crossref","unstructured":"Young, J. G., Cohen, D. J., Waldo, M. C., Feiz, R., & Roth, J. A. Platelet monoamine oxidase activity in children and adolescents with psychiatric disorders.Schizophrenia Bulletin, 1980, in press.","DOI":"10.1093\/schbul\/6.2.324"},{"key":"BF02408428_CR43","unstructured":"Young, J. G., Kyprie, R. M., & Cohen, D. J. Studies of catecholamine-thyroid hormone interactions. III. Lack of association between serum dopamine-beta-hydroxylase activity and thyroxine in euthyroid subjects.Schizophrenia Bulletin, 1980, in press."},{"key":"BF02408428_CR44","first-page":"307","volume-title":"Advances in neurology","author":"M. G. Ziegler","year":"1976","unstructured":"Ziegler, M. G., Lake, C. R., Eldridge, R., & Kopin, I. J. Plasma norepinephrine and dopamine-\u03b2-hydroxylase in dystonia. In R. Eldridge (Ed.),Advances in neurology (Vol. 14). New York: Raven Press, 1976. Pp. 307\u2013315."}],"container-title":["Journal of Autism and Developmental Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02408428.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02408428\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02408428","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T04:03:52Z","timestamp":1627358632000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02408428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,3]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1980,3]]}},"alternative-id":["BF02408428"],"URL":"https:\/\/doi.org\/10.1007\/bf02408428","relation":{},"ISSN":["0162-3257","1573-3432"],"issn-type":[{"value":"0162-3257","type":"print"},{"value":"1573-3432","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,3]]}}}