{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:21:05Z","timestamp":1760919665452,"version":"build-2065373602"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1975,1,1]],"date-time":"1975-01-01T00:00:00Z","timestamp":157766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1975,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Recovery of \u03b2\u2010sitosterol, glycerol triether (1\u2010hexadecyl\u20102,3,\u2010didodecyl glycerol triether), and chromic oxide was studied in African green monkeys and stumptail macaques consuming diets containing 0.75 mg\/Cal cholesterol and 38% of calories as safflower oil or butter. Following oral administration of these compounds, feces were collected daily for 9 days. For all animals, excretion of \u03b2\u2010sitosterol and glycerol triether paralleled one another almost exactly. Except for two animlas, this was also true for chromic acid. Essentially 100% of the administered \u03b2\u2010sitosterol and 90\u201395% of the glycerol triether were recovered; excretion of these markers virtually was complete by day 3. Ninety\u2010two percent of the \u03b2\u2010sitosterol was isolated in the nonsaponifiable lipid extract of the feces with less than 6% in the remaining aqueous phase. A maximum of 3.1% of the \u03b2\u2010sitosterol and 1.8% of the glycerol triether were found in the blood. For stumptail macaques, the major excretory form of \u03b2\u2010sitosterol was the 5\u03b2\u2010derivative. African green monkeys were more variable; one animal excreted the bulk of the \u03b2\u2010sitosterol unchanged while others excreted greater than 80% as the ring\u2010saturated 5\u03b2\u2010derivative. Animals consuming the safflower oil containing diet consistently excreted a greater percentage of the \u03b2\u2010sitosterol unchanged, compared with those animals eating the butter containing diet. There was no evidence for steroid ring degradation in any of the animals used in this study.<\/jats:p>","DOI":"10.1007\/bf02532190","type":"journal-article","created":{"date-parts":[[2006,11,21]],"date-time":"2006-11-21T06:40:04Z","timestamp":1164091204000},"page":"25-32","source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of chromic oxide, glycerol triether, and \u03b2\u2010sitosterol as fecal flow markers in two species of nonhuman primates"],"prefix":"10.1002","volume":"10","author":[{"given":"Richard W. St.","family":"Clair","sequence":"first","affiliation":[{"name":"The Arteriosclerosis Center (Departments of Pathology and Comparative Medicine) The Bowman Gray School of Medicine Winston\u2010Salem North Carolina 27103"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noel D. M.","family":"Lehner","sequence":"additional","affiliation":[{"name":"The Arteriosclerosis Center (Departments of Pathology and Comparative Medicine) The Bowman Gray School of Medicine Winston\u2010Salem North Carolina 27103"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas E.","family":"Hamm","sequence":"additional","affiliation":[{"name":"The Arteriosclerosis Center (Departments of Pathology and Comparative Medicine) The Bowman Gray School of Medicine Winston\u2010Salem North Carolina 27103"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1975,1]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)42653-7"},{"key":"e_1_2_1_3_1","first-page":"374","volume":"9","author":"Grundy S.M.","year":"1968","journal-title":"Ibid."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106102"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)43092-5"},{"key":"e_1_2_1_6_1","first-page":"192","volume":"12","author":"Rosenfeld R.S.","year":"1971","journal-title":"Ibid."},{"key":"e_1_2_1_7_1","first-page":"39","volume":"13","author":"Lofland H.B.","year":"1972","journal-title":"Ibid."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105703"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)42988-8"},{"key":"e_1_2_1_10_1","first-page":"411","volume":"6","author":"Miettinen T.A.","year":"1965","journal-title":"Ibid."},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.116.3023.634"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/12.10.681"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(59)90346-8"},{"key":"e_1_2_1_14_1","first-page":"248","volume-title":"Atherosclerosis. Proceedings of the Second International Symposium","author":"Ahrens E.H.","year":"1970"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)39366-4"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107424"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)42970-0"}],"container-title":["Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aocs.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/BF02532190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T09:03:55Z","timestamp":1760864635000},"score":1,"resource":{"primary":{"URL":"https:\/\/aocs.onlinelibrary.wiley.com\/doi\/10.1007\/BF02532190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1975,1]]}},"alternative-id":["10.1007\/BF02532190"],"URL":"https:\/\/doi.org\/10.1007\/bf02532190","archive":["Portico"],"relation":{},"ISSN":["0024-4201","1558-9307"],"issn-type":[{"type":"print","value":"0024-4201"},{"type":"electronic","value":"1558-9307"}],"subject":[],"published":{"date-parts":[[1975,1]]}}}