{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:44:15Z","timestamp":1760921055452,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[1986,9,1]],"date-time":"1986-09-01T00:00:00Z","timestamp":525916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1986,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To test whether vitamin E deficiency might influence the course of essential fatty acid (EFA) deficiency, Long Evans rats were fed diets containing a marginal amount (1.5% of calories) of 18\u22362\u03c96 or 18\u22363\u03c93 fatty acid with complete absence of the other and with or without vitamin E. Vitamin E contents decreased continuously in serum and liver in all rats fed the E\u2010free diets but in the brains of only the rats fed the marginal 18\u22363\u03c93, E\u2010free diet. It is considered that the vitamin E is cooxidized in the liver with 22\u22366\u03c93, since this fatty acid is very low in livers of the rats fed the marginal 18\u22362\u03c96 diet but much higher in livers of the rats fed the marginal 18\u22363\u03c93 diet. Brain 22\u22366\u03c93 values are comparable for both groups. The source of 22\u22366\u03c93 is evidently in the mother's milk, since following weaning there is a precipitous drop in 22\u22366\u03c93 in serum, liver and carcass of rats on the 18\u22362\u03c96\u2010containing diet. No significant signs of EFA deficiency were seen in the E\u2010deficient rats.<\/jats:p>","DOI":"10.1007\/bf02534059","type":"journal-article","created":{"date-parts":[[2006,11,27]],"date-time":"2006-11-27T08:23:55Z","timestamp":1164615835000},"source":"Crossref","is-referenced-by-count":8,"title":["A relationship between essential fatty acid and vitamin E deficiency"],"prefix":"10.1002","volume":"21","author":[{"given":"Carole S.","family":"Subramanian","sequence":"first","affiliation":[{"name":"Laboratory of Biomedical and Environmental Sciences University of California 900 Veteran Ave. Los Angeles California 90024"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James F.","family":"Mead","sequence":"additional","affiliation":[{"name":"Laboratory of Biomedical and Environmental Sciences University of California 900 Veteran Ave. Los Angeles California 90024"},{"name":"Department of Biological Chemistry, UCLA Medical School and School of Public Health University of California Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1986,9]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"449","volume-title":"The Red Cell: Fifth Ann Arbor Conference","author":"Hochstein P.","year":"1981"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)32911-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/107.7.1200"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/15287398209530292"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/27.9.952"},{"key":"e_1_2_1_7_1","unstructured":"Dhopeshwarkar G. 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