{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:34:59Z","timestamp":1760920499111,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1985,4,1]],"date-time":"1985-04-01T00:00:00Z","timestamp":481161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1985,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Plasma lipoproteins in a diabetic patient with severe hypertrigly ceridemia and turbid, milky plasma were studied and compared with those found in three primary type V hyperlipoproteinemic and in three normal subjects after a fatty meal. All subjects had normal post\u2010heparin lipolytic activity. Lipoprotein electrophoresis of the patient's plasma revealed no chylomicron band, and upon short\u2010time ultracentrifugation the patient's supernatant showed most lipid staining in the pre\u2010\u03b2\u2010lipoprotein region. This supernatant, which in type V hyperlipoproteinemia as well as in normal subjects after a fatty meal, contains a large proportion of apolipoprotein B\u201048 (of intestinal origin) was found in our patient to contain mostly apolipoprotein B\u2010100 (of liver origin). Upon incubation of normal washed platelets with chylomicrons derived either from type V hyperlipoproteinemic or from normal subjects after a fatty meal, platelet aggregation was decreased, whereas the chylomicron\u2010like particles from the patient increased platelet activity. It is, thus suggested that the triglyceride\u2010rich cholesterol\u2010poor lipoproteins are of liver and not of intestinal origin.<\/jats:p>","DOI":"10.1007\/bf02534190","type":"journal-article","created":{"date-parts":[[2006,11,27]],"date-time":"2006-11-27T08:44:49Z","timestamp":1164617089000},"page":"211-215","source":"Crossref","is-referenced-by-count":7,"title":["Chylomicron\u2010like particles in severe hypertriglyceridemia"],"prefix":"10.1002","volume":"20","author":[{"given":"Michael","family":"Aviram","sequence":"first","affiliation":[{"name":"Lipid Research Unit, Blood Bank and Department of Medicine D Rambam Medical Center Haifa 31096 Israel"},{"name":"Faculty of Medicine Technion\u2010Israel Institute of Technology Haifa 31096 Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yael","family":"Sechter","sequence":"additional","affiliation":[{"name":"Lipid Research Unit, Blood Bank and Department of Medicine D Rambam Medical Center Haifa 31096 Israel"},{"name":"Faculty of Medicine Technion\u2010Israel Institute of Technology Haifa 31096 Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Gerald","family":"Brook","sequence":"additional","affiliation":[{"name":"Lipid Research Unit, Blood Bank and Department of Medicine D Rambam Medical Center Haifa 31096 Israel"},{"name":"Faculty of Medicine Technion\u2010Israel Institute of Technology Haifa 31096 Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1985,4]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"329","volume-title":"Structural and Functional Aspects of Lipoproteins in Living Systems","author":"Zilversmit D.B.","year":"1967"},{"key":"e_1_2_1_3_1","first-page":"39","volume-title":"The Hyperlipidemias: Clinical and Laboratory Practice","author":"Lewis B.","year":"1976"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.45.030183.003225"},{"key":"e_1_2_1_5_1","first-page":"145","volume":"24","author":"Stelenhoef A.F.H.","year":"1981","journal-title":"Neth. J. 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