{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T16:12:18Z","timestamp":1770480738409,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1983,4,1]],"date-time":"1983-04-01T00:00:00Z","timestamp":418003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Measurements of pentane and ethane as indices of in vivo lipid peroxidation were made on samples of breath from vitamin C\u2010sufficient and vitamin C\u2010deficient guinea pigs injected with 23 \u03bcl carbon tetrachloride (CCl<jats:sub>4<\/jats:sub>)\/100 g body wt. Vitamin C\u2010deficient animals produced significantly more pentane and ethane after CCl<jats:sub>4<\/jats:sub> treatment than did vitamin C\u2010sufficient guinea pigs. Pretreatment of vitamin C\u2010deficient animals with 75 mg ascorbic acid\/100 g body wt significantly lowered both pentane and ethane evolution. Protection against in vivo lipid peroxidation similar to that provided by ascorbic acid was also found when vitamin C\u2010deficient guinea pigs were pretreated with isoascorbic acid, reduced glutathione, \u03b1\u2010tocopherol or \u03b2\u2010carotene. When animals were pretreated with the radical scavenger mannitol, a protective effect was also observed as measured by pentane evolution.<\/jats:p>","DOI":"10.1007\/bf02534701","type":"journal-article","created":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T02:41:26Z","timestamp":1165286486000},"page":"271-274","source":"Crossref","is-referenced-by-count":91,"title":["The effect of vitamin C on in vivo lipid peroxidation in guinea pigs as measured by pentane and ethane production"],"prefix":"10.1002","volume":"18","author":[{"given":"Karl\u2010Josef","family":"Kunert","sequence":"first","affiliation":[{"name":"Department of Food Science and Technology University of California Davis CA 95616"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Al. 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