{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:39:51Z","timestamp":1761007191017,"version":"build-2065373602"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1993,5,1]],"date-time":"1993-05-01T00:00:00Z","timestamp":736214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1993,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We have studied the activities of \u03949, \u03946 and \u03945 desaturases in rat liver and jejunum when the entero\u2010hepatic circulation was interrupted by either 50 or 75% intestinal resection. Desaturase activities in caecal mucosa were also determined in control and operated rats. Distal small bowel resection significantly altered the activities of desaturase enzymes in liver, jejunum and caecum. Thus, the \u03949 desaturase activity was lower in hepatic microsomes from operated animals, and this decrease was not related to the extent by which the intestine was removed. However, a significant increase in both \u03946 and \u03945 desaturases was found in these animals compared to shamoperated rats, the increase in both desaturases being higher after 75% than after 50% intestinal resection. The activities of \u03949 and \u03945 desaturases were significantly increased in jejunal mucosa of resected rats. The activity of \u03946 desaturase was increased only in 50% resected\u2010animals. An increase in \u03946 desaturase activity was observed in caecal mucosa after resection, together with a decrease in \u03949 desaturase and no change in \u03945 desaturase activities. Enzyme activities were highest in the liver relative to the activity in jejunal and caecal homogenates. In sham rats, the caecal mucosa showed higher \u03949 and \u03946 but lower \u03945 desaturase activities than in jejunal mucosa.<\/jats:p>","DOI":"10.1007\/bf02535948","type":"journal-article","created":{"date-parts":[[2006,11,29]],"date-time":"2006-11-29T12:38:12Z","timestamp":1164803892000},"page":"471-473","source":"Crossref","is-referenced-by-count":8,"title":["Changes in fatty acid desaturation in hepatic and intestinal tissues induced by intestinal resection"],"prefix":"10.1002","volume":"28","author":[{"given":"C. M.","family":"V\u00e1zquez","sequence":"first","affiliation":[{"name":"Departmento de Fisiologia y Biologia Animal Facultad de Farmacia Sevilla 41012 Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. J. G.","family":"Muriana","sequence":"additional","affiliation":[{"name":"Instituto de la Grasa y sus Derivados (C.S.I.C.) Sevilla 41012 Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Ruiz\u2010Gutierrez","sequence":"additional","affiliation":[{"name":"Instituto de la Grasa y sus Derivados (C.S.I.C.) Sevilla 41012 Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1993,5]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0955-2863(90)90064-R"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-711X(90)90114-I"},{"key":"e_1_2_2_4_1","first-page":"901","volume":"14","author":"Molina M.T.","year":"1986","journal-title":"IRCS Med. 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