{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:44:07Z","timestamp":1760921047149,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[1986,7,1]],"date-time":"1986-07-01T00:00:00Z","timestamp":520560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1986,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Young Sprague\u2010Dawley male rats (n=150) were fed a semipurified diet, either without vitamin A (VA), without vitamin E (VE) or supplemented with both vitamins A and E (control). At the end of weeks 0, 1, 3, 5, 6, 7, 8 and 9, groups of rats were anesthetized with methoxyflurane, and blood was collected by cardiac puncture until the rat was exsanguinated. The liver was excised. Whole blood (WB_ from each rat was fractionated into plasma (PLA), leukocytes (LEU), platelets (PLT) and erythrocytes (RBC). Each blood components was extracted with hepatane and livers were extracted with CHCl<jats:sub>3<\/jats:sub>\/CH<jats:sub>3<\/jats:sub>OH (2\u22361, v\/v). The extracts were analyzed for VA and VE by high performance liquid chromatography. The relationship among blood components in the loss of VA was PLT=LEU&gt;WB&gt;PLA. The relationship among blood components in the loss of VE was PLA&gt;RBC&gt;WB&gt;LEU\u2010PLT. VA and VE levels in other blood components decreased precipitously between weeks 0 and 4 in the animals placed on deficient diets. These results and correlation analyses between vitamin contents of blood components and of livers indicate inadequacies for the use of certain blood components as monitors of lipid\u2010soluble vitamin status in the rat.<\/jats:p>","DOI":"10.1007\/bf02536405","type":"journal-article","created":{"date-parts":[[2006,11,29]],"date-time":"2006-11-29T00:38:51Z","timestamp":1164760731000},"page":"465-469","source":"Crossref","is-referenced-by-count":7,"title":["Distribution of vitamins A and E in blood and liver of rats depleted of vitamin A or vitamin E"],"prefix":"10.1002","volume":"21","author":[{"given":"Stanley T.","family":"Omaye","sequence":"first","affiliation":[{"name":"Biochemistry Research Unit Western Human Nutrition Research Center Presidio of San Francisco CA 94129"},{"name":"Nutrients Research Unit Western Regional Research Center Berkeley CA 94710"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faye I.","family":"Chow","sequence":"additional","affiliation":[{"name":"Agricultural Research Service, Western Human Nutrition Research Center United States Department of Agriculture P.O. Box 29997 Presidio of San Francisco CA 94129"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1986,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.1983.tb07456.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408368409165771"},{"key":"e_1_2_1_4_1","first-page":"161","volume":"3","author":"Russell R.M.","year":"1984","journal-title":"Clin. Nutr."},{"key":"e_1_2_1_5_1","first-page":"47","volume":"51","author":"Turnbull J.D.","year":"1981","journal-title":"Int. J. Vitam. Nutr. 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Int."},{"key":"e_1_2_1_16_1","first-page":"685","volume":"20","author":"Lehmann J.","year":"1979","journal-title":"Nutr. Rept. Int."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-99-24485"},{"key":"e_1_2_1_18_1","first-page":"727","volume":"38","author":"Tanaka J.","year":"1979","journal-title":"Immunology"},{"key":"e_1_2_1_19_1","first-page":"99","volume-title":"Handbook of Vitamins","author":"Machlin L.J.","year":"1984"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V55.2.338.338"},{"key":"e_1_2_1_21_1","first-page":"1","volume-title":"Handbook of Vitamins","author":"Olson J.A.","year":"1984"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/105.12.1600"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/107.8.1418"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01923121"},{"key":"e_1_2_1_25_1","first-page":"125","volume":"54","author":"Frigg M.","year":"1983","journal-title":"Int. J. Vitam. Nutr. 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