{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:16:52Z","timestamp":1790176612384,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1995,6,1]],"date-time":"1995-06-01T00:00:00Z","timestamp":801964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1995,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fat absorption may be compromised by pancreatic or bile insufficiency, resulting in low uptake of essential fatty acid and energy. Using a rat model of malabsorption, we examined the absorption of defined triglycerides with medium\u2010chain fatty acids (MCFA) in the<jats:italic>sn<\/jats:italic>\u20101,3 positions and essential fatty acids in the<jats:italic>sn<\/jats:italic>\u20102 position (MLM) compared to other fats. The thoracic duct was cannulated for collection of lymph, and the common bile and pancreatic duct was cannulated to divert both the pancreatic juice and bile. The rats were given a single bolus of triglyceride as a taurocholate emulsion. Fat absorption was measured from collected lymph samples. The triglycerides administered were a defined triglyceride, MLM [mainly (8\u22360\/10\u22360)\u2010(18\u22362n\u22126)\u2010(8\u22360\/10\u22360)], a similar triglyceride subjected to chemical randomization, a mixture of medium\u2010chain triglycerides and soybean oil, and soybean oil, respectively. The first three triglycerides had approximately 36 wt% linoleic acid (18\u22362n\u22126) content. Administration of defined triglyceride was followed by significantly higher lymphatic level (wt%) of 18\u22362n\u22126 (<jats:italic>P<\/jats:italic>&lt;0.01) as well as a relative enhancement in mol% of 18\u22362n\u22126 (<jats:italic>P<\/jats:italic>&lt;0.05) compared to the other triglycerides. Lymphatic absorption of MCFA was similar in the three first groups but not as efficient as for long\u2010chain fatty acids. Our results indicate that defined triglycerides thus may provide a means to increase absorption of essential fatty acids in fat malabsorption, such as that seen in cystic fibrosis, or for pre\u2010term infants.<\/jats:p>","DOI":"10.1007\/bf02537026","type":"journal-article","created":{"date-parts":[[2006,11,29]],"date-time":"2006-11-29T15:00:56Z","timestamp":1164812456000},"page":"521-526","source":"Crossref","is-referenced-by-count":53,"title":["Absorption of triglycerides with defined or random structure by rats with biliary and pancreatic diversion"],"prefix":"10.1002","volume":"30","author":[{"given":"Michael S\u00f8berg","family":"Christensen","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Nutrition Technical University of Denmark Building 224 Lyngby DK\u20102800 Denmark"},{"name":"Center for Food Research Technical University of Denmark Building 224 Lyngby DK\u20102800 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"M\u00fcllertz","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S Bagsvaerd DK\u20102880 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl\u2010Erik","family":"H\u00f8y","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Nutrition Technical University of Denmark Building 224 Lyngby DK\u20102800 Denmark"},{"name":"Center for Food Research Technical University of Denmark Building 224 Lyngby DK\u20102800 Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1995,6]]},"reference":[{"key":"e_1_2_2_2_1","first-page":"261","volume-title":"Fat Absorption","author":"Parsons H.G.","year":"1986"},{"key":"e_1_2_2_3_1","volume-title":"Lingual and Gastric Lipases: Their Role in Fat Digestion","author":"Hamosh M.","year":"1990"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/36.5.950"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02537271"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02537273"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(69)86739-1"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02535779"},{"key":"e_1_2_2_9_1","first-page":"1349","volume":"33","author":"Bollman J.L.","year":"1948","journal-title":"J. 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