{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:08:22Z","timestamp":1773288502629,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1983,5,1]],"date-time":"1983-05-01T00:00:00Z","timestamp":420595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lipids"],"published-print":{"date-parts":[[1983,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Seventy\u2010two surgically obtained Dupuytren's disease palmar\u2010fat (DDPF) specimens and 18 location\u2010matched speciments from patients not suffering from this disease (controls) were studied for their total lipid composition and de novo lipogenic activity. Incubation of \u201cDDPF\u201d with 1\u2010[<jats:sup>14<\/jats:sup>C]acetate in oxygen produced [<jats:sup>14<\/jats:sup>C]palmitate and [<jats:sup>14<\/jats:sup>C]stearate in approximately equal yields as those obtained from \u201ccontrols\u201d. No [<jats:sup>14<\/jats:sup>C]octanate was formed in any of the palmar\u2010fat preparations. The lipids and fatty acid analysis revealed differences; (a) DDPF specimens were richer in free fatty acids, methyl esters of fatty acids and freecholesterol than specimens of controls (b) DDPF specimens contained less phospholipids. (c) DDPF specimens showed a significantly higher content of octanoate and other short\u2010chain fatty acids than specimens of controls. The above findings are not incompatible with the results expected if some mild hypoxia occurred in DDPF; this has been suggested in the statistical correlations observed for this disease and alcoholism with liver involvement.<\/jats:p>","DOI":"10.1007\/bf02537234","type":"journal-article","created":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T03:03:35Z","timestamp":1165287815000},"page":"371-374","source":"Crossref","is-referenced-by-count":32,"title":["Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease"],"prefix":"10.1002","volume":"18","author":[{"given":"Joseph L.","family":"Rabinowitz","sequence":"first","affiliation":[{"name":"Veterans Administration Medical Center University and Woodland Avenues Philadelphia PA 19104"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Lee","family":"Ostermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. W.","family":"Bora","sequence":"additional","affiliation":[{"name":"Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia PA 19104"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Staeffen","sequence":"additional","affiliation":[{"name":"Hospital Saint Andr\u00e9 1, Rue Jean\u2010Burguet Bordeaux 33075 France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1983,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.129.4.561"},{"key":"e_1_2_1_3_1","first-page":"352","volume":"5","author":"Dupuytren G.","year":"1831","journal-title":"J. Univ. Med. 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