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The phospholipid and cholesterol contents relative to protein were similar in both groups, showing a cholesterol\/phospholipid molar ratio of 0.6. The distribution of phospholipid classes was also unaffected by the diet. In contrast, fatty acid profiles of the two phospholipid main classes, phosphatidylcholine and phosphatidylethanolamine were altered by EFA deficiency. Linoleic acid (18\u22362n\u22126) was largely reduced, whereas arachidonic acid (20\u22364n\u22126) only slightly decreased in EFA\u2010deficient pigs. The unsaturation index was essentially maintained by high levels of oleic acid (18\u22361n\u22129) and by conversion of oleic acid to 5,8,11\u2010eicosatrienoic acid (20\u22363n\u22129). Finally, during the period of EFA deficiency, the lipid composition of BPM of the intestinal mucosal cells was little affected, suggesting a preferential uptake of 20\u22364n\u22126 and (or) precursor mobilized from other tissues. However, an effect of dietary treatment on the function of membrane\u2010associated proteins cannot be ruled out.<\/jats:p>","DOI":"10.1007\/bf02543967","type":"journal-article","created":{"date-parts":[[2007,1,4]],"date-time":"2007-01-04T19:33:39Z","timestamp":1167939219000},"page":"175-181","source":"Crossref","is-referenced-by-count":16,"title":["Effect of essential fatty acid deficiency on lipid composition of basolateral plasma membrane of pig intestinal mucosal cells"],"prefix":"10.1002","volume":"26","author":[{"given":"V\u00e9ronique","family":"Duranthon","sequence":"first","affiliation":[{"name":"Laboratoire de Nutrition et Securit\u00e9 Alimentaire CRJ\u2010INRA Domaine de Vilvert Jour\u2010en\u2010Josas Cedex 78352 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Fr\u00e9mont","sequence":"additional","affiliation":[{"name":"Laboratoire de Nutrition et Securit\u00e9 Alimentaire CRJ\u2010INRA Domaine de Vilvert Jour\u2010en\u2010Josas Cedex 78352 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude L.","family":"L\u00e9ger","sequence":"additional","affiliation":[{"name":"Laboratoire de Nutrition et Securit\u00e9 Alimentaire CRJ\u2010INRA Domaine de Vilvert Jour\u2010en\u2010Josas Cedex 78352 France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1991,3]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0300-9629(83)90334-1","volume":"76","author":"Clandinin M.T.","year":"1983","journal-title":"Comp. 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