{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:23:44Z","timestamp":1762100624318},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1988,10,1]],"date-time":"1988-10-01T00:00:00Z","timestamp":591667200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Calcif Tissue Int"],"published-print":{"date-parts":[[1988,10]]},"DOI":"10.1007\/bf02555140","type":"journal-article","created":{"date-parts":[[2007,2,7]],"date-time":"2007-02-07T15:21:40Z","timestamp":1170861700000},"page":"235-243","source":"Crossref","is-referenced-by-count":39,"title":["Increase of bone volume in vitamin D-repleted rats by massive administration of 24R,25(OH)2D3"],"prefix":"10.1007","volume":"43","author":[{"given":"Toshitaka","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahide","family":"Kurokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Orimo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02555140_CR1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/0165-6147(81)90257-1","volume":"2","author":"MR Walters","year":"1981","unstructured":"Walters MR, Hunziker W, Norman AW (1981) Ubiquitous effects of the vitamin D endocrine system. Trends In Pharmacolog Sci 2:42\u201344","journal-title":"Trends In Pharmacolog Sci"},{"key":"BF02555140_CR2","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/ki.1983.163","volume":"24","author":"YL Chan","year":"1983","unstructured":"Chan YL, Mason RS, Parmentier M, Savdie E, Lissner D, Posen D (1983) Vitamin D metabolism in nephrotic rats. Kidney Int 24:336\u2013341","journal-title":"Kidney Int"},{"key":"BF02555140_CR3","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1172\/JCI111246","volume":"73","author":"AM Parfitt","year":"1984","unstructured":"Parfitt AM, Mathew CHE, Brommage R, Jarnagin K, DeLuca HF (1984) Calcitriol but no other metabolite of vitamin D is essential for normal bone growth and development in the rat. J Clin Invest 73:576\u2013586","journal-title":"J Clin Invest"},{"key":"BF02555140_CR4","doi-asserted-by":"crossref","first-page":"7163","DOI":"10.1016\/S0021-9258(18)50299-4","volume":"254","author":"Y Tanaka","year":"1979","unstructured":"Tanaka Y, DeLuca HF, Kobayashi Y, Taguchi T, Ikekawa N, Morisaki M (1979) Biological activity of 24,24-difluoro-25-hydroxyvitamin D3. Effect of blocking of 24-hydroxylation on the functions of vitamin D. J Biol Chem 254:7163\u20137167","journal-title":"J Biol Chem"},{"key":"BF02555140_CR5","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1210\/endo-102-4-1269","volume":"102","author":"MT Corvol","year":"1978","unstructured":"Corvol MT, Dumontier MF, Garabedian B, Rapport R (1978) Vitamin D and cartilage. II. Biological activity of 25-hydroxycholecalciferol and 24,25- and 1,25-dihydroxycholecalciferols on cultured growth plate chondrocytes. Endocrinology 102:1209\u20131274","journal-title":"Endocrinology"},{"key":"BF02555140_CR6","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/286262a0","volume":"286","author":"H Endo","year":"1980","unstructured":"Endo H, Kiyoki M, Kawashima K, Naruchi T (1980) Vitamin D3 metabolites and PTH synergistically stimulate bone formation of chick embryonic femur in vitro. Nature 286:262\u2013264","journal-title":"Nature"},{"key":"BF02555140_CR7","first-page":"899","volume":"217","author":"JE Gordeladze","year":"1986","unstructured":"Gordeladze JE, Gautvik KM (1986) Hydroxycholecalciferols modulate parathyroid hormone and calcitonin-sensitive adenylyl cyclase in bone and kidney of rats, a possible physiological role for 24,25-dihydroxyvitamin D3. Biochem J 217:899\u2013902","journal-title":"Biochem J"},{"key":"BF02555140_CR8","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1126\/science.684411","volume":"210","author":"HL Henry","year":"1978","unstructured":"Henry HL, Norman AW (1978) Vitamin D: two dihydroxylated metabolites are required for normal chicken egg hatchability. Science 210:835\u2013837","journal-title":"Science"},{"key":"BF02555140_CR9","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/BF02409505","volume":"33","author":"A Mahgoub","year":"1981","unstructured":"Mahgoub A (1981) Interaction between 24R,25-dihydroxycholecalciferol and 1,25-dihydroxycholecalciferol on45Ca release from bone in vitro. Calcif Tissue Int 33:663\u2013666","journal-title":"Calcif Tissue Int"},{"key":"BF02555140_CR10","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/276517a0","volume":"276","author":"A Ornoy","year":"1978","unstructured":"Ornoy A, Goodwin D, Noff D, Edelstein S (1978) 24,25-Dihydroxyvitamin D is a metabolite of vitamin D essential for bone formation. Nature 276:517\u2013519","journal-title":"Nature"},{"key":"BF02555140_CR11","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1042\/bj2140293","volume":"214","author":"D S\u00f6mjen","year":"1983","unstructured":"S\u00f6mjen D, Binderman I, Weisman Y (1983) The effects of 24R,25-dihydroxycholecalciferol and 1 alpha, 25-dihydroxycholecalciferol on ornithine decarboxylase activity and DNA synthesis in the epiphysis and diaphysis of rat bone in the duodenum. Biochem J 214:293\u2013298","journal-title":"Biochem J"},{"key":"BF02555140_CR12","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1210\/endo-118-6-2217","volume":"118","author":"CS Tam","year":"1986","unstructured":"Tam CS, Heershe J, Jones G, Murray TM, Rasmussen H (1986) The effect of vitamin D on bone in vivo. Endocrinology 118:2217\u20132224","journal-title":"Endocrinology"},{"key":"BF02555140_CR13","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/BF02555702","volume":"40","author":"S Wientroub","year":"1987","unstructured":"Wientroub S, Price PA, Reddi AH (1987) The dichotomy in the effects of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 on bone gamma-carbocyglutamic acid-containing protein in serum and bone in vitamin D-deficient rats. Calcif Tissue Int 40:166\u2013172","journal-title":"Calcif Tissue Int"},{"key":"BF02555140_CR14","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0003-9861(86)90563-1","volume":"249","author":"F Wilhelm","year":"1986","unstructured":"Wilhelm F, Ross FP, Norman AW (1986) Specific binding of 24R,25-dihydroxyvitamin D3 to chick intestinal mucosa: 24R,25-dihydroxyvitamin D3 is an allosteric effector of 1,25-dihydroxyvitamin D3 binding. Arch Biochem Biophy 249:88\u201394","journal-title":"Arch Biochem Biophy"},{"key":"BF02555140_CR15","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/BF02409504","volume":"33","author":"SC Manolagas","year":"1981","unstructured":"Manolagas SC, Deftos LJ (1981) Comparison of 1,25-,25-, and 24,25-hydroxylated vitamin D3 binding in fetal rat calvariae and osteogenic sarcoma cells. Calcif Tissue Int 33:655\u2013661","journal-title":"Calcif Tissue Int"},{"key":"BF02555140_CR16","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1093\/ajcp\/45.3.290","volume":"45","author":"HV Connerty","year":"1966","unstructured":"Connerty HV, Briggs AR (1966) Determination of serum calcium by means of orthocresolphthalein complexone. Am J Clin Pathol 45:290\u2013296","journal-title":"Am J Clin Pathol"},{"key":"BF02555140_CR17","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/8756-3282(85)90319-9","volume":"6","author":"JR Hagaman","year":"1985","unstructured":"Hagaman JR, Sanchez TV, Myers RC (1985) The effect of lactation on the mineral distribution profile of the rat femur by single photon absorptiometry. Bone 6:301\u2013305","journal-title":"Bone"},{"key":"BF02555140_CR18","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/0009-8981(64)90067-1","volume":"10","author":"E Rice","year":"1963","unstructured":"Rice E, Lapara CZ (1963) Rapid ultramicrospectrophotometric determination of magnesium. Clin Chim Acta 10:360\u2013364","journal-title":"Clin Chim Acta"},{"key":"BF02555140_CR19","first-page":"395","volume":"34","author":"GM Hass","year":"1958","unstructured":"Hass GM, Trueheart RE, Taylor CB, Stumpe M (1958) An experimental histologic study of hypervitaminosis D. Am J Pathol 34:395\u2013431","journal-title":"Am J Pathol"},{"key":"BF02555140_CR20","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0021-9258(18)73738-1","volume":"128","author":"H Schneider","year":"1939","unstructured":"Schneider H, Steenbock H (1939) A low phosphorus diet and the response of rats of vitamin D2. J Biol Chem 128:159\u2013171","journal-title":"J Biol Chem"},{"key":"BF02555140_CR21","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/BF02407184","volume":"31","author":"JA Gallagher","year":"1980","unstructured":"Gallagher JA, Lawson DEM (1980) Histological observations on the failure of rachitic rat bones to respond to 1,25(OH)2D3. Calcif Tissue Int 31:215\u2013223","journal-title":"Calcif Tissue Int"},{"key":"BF02555140_CR22","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1515\/9783112327203-102","volume-title":"Vitamin D: biochemical, chemical and clinical aspects related to calcium metabolism","author":"DL Hartenbower","year":"1977","unstructured":"Hartenbower DL, Stanley TM, Coburn JW, Norman AW (1977) Serum and renal histologic changes in the rat following administration of toxic amounts of 1,25(OH)2D3. In: Norman AW, Schaefer K, Coburn JW, DeLuca HF, Fraser D, Grigoleit HG, Herrath DV (eds) Vitamin D: biochemical, chemical and clinical aspects related to calcium metabolism. Walter de Gruyter, Berlin, pp 587\u2013589"},{"key":"BF02555140_CR23","first-page":"237","volume":"28","author":"ML Queille","year":"1978","unstructured":"Queille ML, Miravet LM, Bordier P, Redel J (1978) The action of vitamin D metabolites (25(OH)D3, 1,25(OH)2D3, 24,25(OH)2D3, 25,26(OH)2D3) on vitamin D-deficient rats. Biomedicine 28:237\u2013242","journal-title":"Biomedicine"},{"key":"BF02555140_CR24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1210\/endo-28-1-83","volume":"28","author":"GG Day","year":"1941","unstructured":"Day GG, Follis RH (1941) Skeletal changes in rats receiving estradiol benzoate as indicated by histological studies and determinations of bone ash, serum calcium and phosphatase. Endocrinology 28:83\u201393","journal-title":"Endocrinology"},{"key":"BF02555140_CR25","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/0002-9343(67)90111-8","volume":"43","author":"GV Foster","year":"1967","unstructured":"Foster GV, Doyle FH, Bordier PB, Matrajt H, Tun-Chot S (1967) Roentgenologic and histologic changes in bone produced by thyrocalcitonin. Am J Med 43:691\u2013695","journal-title":"Am J Med"},{"key":"BF02555140_CR26","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/214388a0","volume":"214","author":"AW Wase","year":"1967","unstructured":"Wase AW, Solewski J, Rickes E, Seidenberg J (1967) Action of thyrocalcitonin on bone. Nature 214:388\u2013389","journal-title":"Nature"},{"key":"BF02555140_CR27","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/S0140-6736(70)91271-7","volume":"i","author":"DN Kalu","year":"1970","unstructured":"Kalu DN, Pennock J, Doyle FH, Foster GV (1970) Parathyroid hormone and experimental osteosclerosis. Lancet (i):1363\u20131366","journal-title":"Lancet"},{"key":"BF02555140_CR28","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/BF02547219","volume":"11","author":"R Schenk","year":"1973","unstructured":"Schenk R, Merz WZ, Muhlbauer R, Russell RGG, Fleisch H (1973) Effect of ethane-1-hydroxy-1,1-diphosphonate(EHDP) and dichloromethylene diphosphonate(Cl2MDP) on the calcification and resorption of cartilage metaphysis of rats. Calcif Tissue Int 11:196\u2013214","journal-title":"Calcif Tissue Int"},{"key":"BF02555140_CR29","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2106\/00004623-195032010-00014","volume":"32A","author":"MR Urist","year":"1950","unstructured":"Urist MR, Budy AM, McLean FC (1950) Endosteal-bone formation in estrogen-treated mice. J Bone Joint Surg 32A:143\u2013162","journal-title":"J Bone Joint Surg"},{"key":"BF02555140_CR30","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/BF02556620","volume":"40","author":"J Aceitero","year":"1987","unstructured":"Aceitero J, Gaytan F, Ranz FB (1987) Effects of neonatal estrogenization on rat bone development: a histomorphometric study. Calcif Tissue Int 40:189\u2013193","journal-title":"Calcif Tissue Int"},{"key":"BF02555140_CR31","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0021-9258(17)33892-9","volume":"251","author":"MF Holick","year":"1976","unstructured":"Holick MF, Baxter LA, Scraufrogel PK, Tavela TE, DeLuca HF (1976) Metabolism and biological activity of 24,25-dihydroxyvitamin D3 in the chick. J Biol Chem 251:397\u2013402","journal-title":"J Biol Chem"}],"container-title":["Calcified Tissue International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02555140.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02555140\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02555140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,8]],"date-time":"2021-08-08T13:29:51Z","timestamp":1628429391000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02555140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,10]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1988,10]]}},"alternative-id":["BF02555140"],"URL":"https:\/\/doi.org\/10.1007\/bf02555140","relation":{},"ISSN":["0171-967X","1432-0827"],"issn-type":[{"value":"0171-967X","type":"print"},{"value":"1432-0827","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,10]]}}}