{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:01:17Z","timestamp":1782298877011,"version":"3.54.5"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1986,12]]},"DOI":"10.1007\/bf02555345","type":"journal-article","created":{"date-parts":[[2007,2,7]],"date-time":"2007-02-07T19:19:49Z","timestamp":1170875989000},"page":"789-792","source":"Crossref","is-referenced-by-count":60,"title":["Toxic megacolon"],"prefix":"10.1097","volume":"29","author":[{"given":"J.","family":"Heppell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Farkouh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Dub\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"P\u00e9loquin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Bernard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"BF02555345_CR1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1097\/00004836-198504000-00007","volume":"7","author":"AJ Greenstein","year":"1985","unstructured":"Greenstein AJ, Sachar DB, Gibas A, Heimann T, Janowitz HD, Aufses AH Jr. Outcome of toxic dilatation in ulcerative and Crohn's colitis. J Clin Gastroenterol 1985;7:137\u201344.","journal-title":"J Clin Gastroenterol"},{"key":"BF02555345_CR2","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/0016-5085(85)90230-6","volume":"89","author":"JP McManus","year":"1985","unstructured":"McManus JP. The therapeutic dilemma of toxic megacolon. Gastroenterology 1985;89:1201\u20132.","journal-title":"Gastroenterology"},{"key":"BF02555345_CR3","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1136\/gut.3.4.306","volume":"3","author":"ND Gallagher","year":"1962","unstructured":"Gallagher ND, Goulston SJ, Wyndham N, Morrow W. The management of fulminant ulcerative colitis. Gut 1962;3:306\u201311.","journal-title":"Gut"},{"key":"BF02555345_CR4","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1136\/bmj.4.5737.703","volume":"4","author":"JC Goligher","year":"1970","unstructured":"Goligher JC, Hoffman DC, DeDombal FT. Surgical treatment of severe attacks of ulcerative colitis, with special reference to the advantages of early operation. Br Med J 1970;4:703\u20136.","journal-title":"Br Med J"},{"issue":"suppl","key":"BF02555345_CR5","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.0954-6820.1977.tb19359.x","volume":"603","author":"H Schjonsby","year":"1977","unstructured":"Schjonsby H, Heimann P, Kremer D, et al. Intensive treatment in severe acute attacks of ulcerative colitis. Acta Med Scand [suppl] 1977;603:43\u20136.","journal-title":"Acta Med Scand"},{"key":"BF02555345_CR6","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0016-5085(19)33962-9","volume":"57","author":"KN Jalan","year":"1969","unstructured":"Jalan KN, Sircus W, Card WL, et al. An experience of ulcerative colitis: I. Toxic dilation in 55 cases. Gastroenterology 1969;57:68\u201382.","journal-title":"Gastroenterology"},{"key":"BF02555345_CR7","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S0016-5085(19)36490-X","volume":"16","author":"RH Marshak","year":"1950","unstructured":"Marshak RH, Lester LJ, Friedman AI. Megacolon, a complication of ulcerative colitis. Gastroenterology 1950;16:768\u201372.","journal-title":"Gastroenterology"},{"key":"BF02555345_CR8","first-page":"318","volume":"64","author":"PF Schofield","year":"1982","unstructured":"Schofield PF. Toxic dilatation and perforation in inflammatory bowel disease. Ann R Coll Surg Engl 1982;64:318\u201320.","journal-title":"Ann R Coll Surg Engl"},{"key":"BF02555345_CR9","first-page":"21","volume":"26","author":"MS Madison","year":"1951","unstructured":"Madison MS, Bargen JA. Fulminating ulcerative colitis with unusual segmental dilatation of the colon: report of a case. Mayo Clin Proc 1951;26:21\u20134.","journal-title":"Mayo Clin Proc"},{"key":"BF02555345_CR10","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1016\/S0140-6736(81)91350-7","volume":"2","author":"PJ Whorwell","year":"1981","unstructured":"Whorwell PJ, Isaacson P. Toxic dilatation of colon in Crohn's disease. Lancet 1981;2:1334\u20137.","journal-title":"Lancet"},{"key":"BF02555345_CR11","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/S0039-6109(16)39254-4","volume":"50","author":"RB Turnbull Jr","year":"1970","unstructured":"Turnbull RB Jr, Weakley FL, Hawk WA, Schofield P. Choice of operation for the toxic megacolon phase of nonspecific ulcerative colitis. Surg Clin North Am 1970;50:1151\u201369.","journal-title":"Surg Clin North Am"},{"key":"BF02555345_CR12","first-page":"117","volume":"63","author":"AJ Greenstein","year":"1975","unstructured":"Greenstein AJ, Kark AE, Dreiling DA. Crohn's disease of the colon: III. Toxic dilatation of the colon in Crohn's colitis. Am J Gastroenterol 1975;63:117\u201328.","journal-title":"Am J Gastroenterol"},{"key":"BF02555345_CR13","first-page":"1014","volume":"112","author":"E Farkouh","year":"1983","unstructured":"Farkouh E, Wassef R, Allard M, Atlas H. Le megacolon toxique dans les maladies inflammatoires du c\u00f4lon. L'union M\u00e9dicale du Canada (Montr\u00e9al) 1983;112:1014\u20136.","journal-title":"L'union M\u00e9dicale du Canada (Montr\u00e9al)"},{"key":"BF02555345_CR14","first-page":"644","volume-title":"Clinical gastroenterology","author":"HM Spiro","year":"1970","unstructured":"Spiro HM. Clinical gastroenterology. London: MacMillan, 1970: 644\u201366."},{"key":"BF02555345_CR15","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/BF02553662","volume":"25","author":"JB Cone","year":"1982","unstructured":"Cone JB, Wetzel W. Toxic megacolon secondary to pseudomembranous colitis. Dis Colon Rectum 1982;25:478\u201382.","journal-title":"Dis Colon Rectum"},{"key":"BF02555345_CR16","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1001\/archsurg.1973.01350170046011","volume":"106","author":"JT Adams","year":"1973","unstructured":"Adams JT. Toxic dilatation of the colon: A surgical disease. Arch Surg 1973;106:678\u201382.","journal-title":"Arch Surg"},{"key":"BF02555345_CR17","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0016-5085(62)80021-3","volume":"42","author":"FW Smith","year":"1962","unstructured":"Smith FW, Law DH, Nickel WF Jr, Sleisenger MH. Fulminant ulcerative colitis with toxic dilation of the colon: medical and surgical management of eleven cases with observations regarding etiology. Gastroenterology 1962;42:233\u201343.","journal-title":"Gastroenterology"},{"key":"BF02555345_CR18","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1136\/bmj.285.6340.475-a","volume":"285","author":"RP Bolton","year":"1982","unstructured":"Bolton RP, Read AE. Clostridium difficile in toxic megacolon complicating acute inflammatory bowel disease. Br Med J 1982;285:475\u20136.","journal-title":"Br Med J"},{"key":"BF02555345_CR19","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/S0016-5085(74)80165-4","volume":"66","author":"SC Binder","year":"1974","unstructured":"Binder SC, Patterson JF, Glotzer DJ. Toxic megacolon in ulcerative colitis. Gastroenterology 1974;66:909\u201315.","journal-title":"Gastroenterology"},{"key":"BF02555345_CR20","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/0002-9610(84)90042-4","volume":"147","author":"CS Grant","year":"1984","unstructured":"Grant CS, Dozois RR. Toxic megacolon: ultimate fate of patients after successful medical management. Am J Surg 1984;147:106\u201310.","journal-title":"Am J Surg"}],"container-title":["Diseases of the Colon &amp; Rectum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1007\/BF02555345","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T20:38:18Z","timestamp":1707597498000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003453-198629120-00001"}},"subtitle":["An analysis of 70 cases"],"short-title":[],"issued":{"date-parts":[[1986,12]]},"references-count":20,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1986]]}},"URL":"https:\/\/doi.org\/10.1007\/bf02555345","relation":{},"ISSN":["0012-3706"],"issn-type":[{"value":"0012-3706","type":"print"}],"subject":[],"published":{"date-parts":[[1986,12]]}}}