{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:15:36Z","timestamp":1759331736169},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1991,1,1]],"date-time":"1991-01-01T00:00:00Z","timestamp":662688000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Calcif Tissue Int"],"published-print":{"date-parts":[[1991,1]]},"DOI":"10.1007\/bf02555900","type":"journal-article","created":{"date-parts":[[2007,2,7]],"date-time":"2007-02-07T15:46:51Z","timestamp":1170863211000},"page":"35-42","source":"Crossref","is-referenced-by-count":19,"title":["Modulation by epidermal growth factor of the basal 1,25(OH)2D3 receptor level and the heterologous up-regulation of the 1,25(OH)2D3 receptor in clonal osteoblast-like cells"],"prefix":"10.1007","volume":"49","author":[{"given":"J. P. T. M.","family":"van Leeuwen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. A. P.","family":"Pols","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. P.","family":"Schilte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. J.","family":"Visser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"Birkenh\u00e4ger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02555900_CR1","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1126\/science.887939","volume":"197","author":"BE Kream","year":"1977","unstructured":"Kream BE, Jose M, Yamada S, De Luca HF (1977) A specific high affinity macromolecule for 1,25-dihydroxyvitamin D3 in fetal bone. Science 197:1086\u20131088","journal-title":"Science"},{"key":"BF02555900_CR2","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0014-5793(80)80744-7","volume":"115","author":"NC Partridge","year":"1980","unstructured":"Partridge NC, Frampton RJ, Eisman JA, Michelangeli VP, Elms E, Bradley TR, Martin TJ (1980) Receptors for 1,25(OH)2D3 enriched in cloned osteoblast-like rat osteogenic sarcoma cells. FEBS Lett 115:139\u2013142","journal-title":"FEBS Lett"},{"key":"BF02555900_CR3","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1083\/jcb.94.2.379","volume":"94","author":"CM Silve","year":"1982","unstructured":"Silve CM, Kradek GT, Jones AL, Arnaud CD (1982) Parathyroid hormone receptor in intact embryonic chicken bone: characteriaation and cellular localization. J Cell Biol 94:379\u2013386","journal-title":"J Cell Biol"},{"key":"BF02555900_CR4","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1210\/endo-122-4-1224","volume":"122","author":"TL Clemens","year":"1988","unstructured":"Clemens TL, Garrett KP, Zhou X-Y, Pike JW, Hausler MR, Dempster DW (1988) Immunocytochemical localization of the 1,25-dihydroxyvitamin D3 receptor in target cells. Endocrinol 122:1224\u20131230","journal-title":"Endocrinol"},{"key":"BF02555900_CR5","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1172\/JCI108311","volume":"57","author":"LR Forte","year":"1976","unstructured":"Forte LR, Nickols GA, Anast CS (1976) Renal adenylate cyclase and the interrelationship between parathyroid hormone and vitamin D in the regulation of urinary phosphate and adenosine cyclclic 3\u2032, 5\u2032-monophosphate excretion. J Clin Invest 57:559\u2013568","journal-title":"J Clin Invest"},{"key":"BF02555900_CR6","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/0006-291X(84)90400-5","volume":"123","author":"J Rubin","year":"1984","unstructured":"Rubin J, Catherwood BD (1984) 1,25-dihydroxyvitamin D causes attenuation of cyclic AMP responses in monocyte-like cells. Biochem Biophys Res Commun 123:210\u2013215","journal-title":"Biochem Biophys Res Commun"},{"key":"BF02555900_CR7","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/BF02405370","volume":"36","author":"TL Chen","year":"1984","unstructured":"Chen TL, Feldman D (1984) Modulation of PTH-stimulated cAMP in cultured rodent bone cells. The effect of 1,25(OH)2D3 and its interaction with glucocorticoids. Calcif Tissue Int 36:580\u2013585","journal-title":"Calcif Tissue Int"},{"key":"BF02555900_CR8","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0021-9258(20)71159-2","volume":"260","author":"BD Catherwood","year":"1985","unstructured":"Catherwood BD (1985) 1,25-dihydroxycholecalciferol and glucocorticoid regulation of adenylate cyclase in an osteoblast-like cell line. J Biol Chem 260:736\u2013743","journal-title":"J Biol Chem"},{"key":"BF02555900_CR9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1042\/bj2310011","volume":"231","author":"M Kubota","year":"1985","unstructured":"Kubota M, Ng KW, Martin TJ (1985) Effect of 1,25-dihydroxyvitamin D3 on cyclic AMP responses to hormones in clonal osteogenic sarcoma cells. Biochem J 231:11\u201317","journal-title":"Biochem J"},{"key":"BF02555900_CR10","first-page":"397","volume":"1","author":"HAP Pols","year":"1986","unstructured":"Pols HAP, Schilte JP, Herrmann-Erlee MPM, Visser TJ, Birkenh\u00e4ger JC 1986 The effects of 1,25-dihydroxyvitamin D3 on growth, alkaline phosphatase and adenylate cyclase of rat osteoblast-like cells. Bone Miner 1:397\u2013405","journal-title":"Bone Miner"},{"key":"BF02555900_CR11","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0006-291X(88)80883-0","volume":"156","author":"HAP Pols","year":"1988","unstructured":"Pols HAP, van Leeuwen JPTM, Schilte JP, Visser TJ, Birkenh\u00e4ger JC (1988) Heterologous up-regulation of the 1,25-dihydroxyvitamin D3 receptor by parathyroid hormone (PTH) and PTH-like peptide in osteoblast-like cells. Biochem Biophys Res Commun 156:588\u2013594","journal-title":"Biochem Biophys Res Commun"},{"key":"BF02555900_CR12","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/0006-291X(78)90638-1","volume":"85","author":"AH Tashjian Jr","year":"1978","unstructured":"Tashjian AH Jr, Levine L (1978) Epidermal growth factor simulated prostaglandin production and bone resorption in cultured mouse calvaria. Biochem Biophys Res Commun 85:966\u2013975","journal-title":"Biochem Biophys Res Commun"},{"key":"BF02555900_CR13","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1210\/endo-107-1-270","volume":"107","author":"LG Raisz","year":"1980","unstructured":"Raisz LG, Simmons HA, Sandberg AL, Canalis E (1980) Direct stimulation of bone resorption by epidermal growth factor. Endocrinology 107:270\u2013273","journal-title":"Endocrinology"},{"key":"BF02555900_CR14","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/jcp.1041090305","volume":"109","author":"MA Shupnik","year":"1981","unstructured":"Shupnik MA, Tashjian AH Jr (1981) Functional receptors for epidermal growth factor on human osteosarcoma cells. J Cell Physiol 109:403\u2013410","journal-title":"J Cell Physiol"},{"key":"BF02555900_CR15","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/BF02405050","volume":"35","author":"KW Ng","year":"1983","unstructured":"Ng KW, Partridge NC, Niall M, Martin TJ (1983) Epidermal growth factor receptors in clonal lines of a rat osteogenic sarcoma and in osteoblast-rich rat bone cells. Calcif Tissue Int 35:298\u2013303","journal-title":"Calcif Tissue Int"},{"key":"BF02555900_CR16","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/BF02405091","volume":"35","author":"M Kumegawa","year":"1983","unstructured":"Kumegawa M, Hiramatsu M, Hatakeyama K, Yajima T, Kodama H, Osaki T, Kurisu K (1983) Effects of epidermal growth factor on osteoblastic cells in vitro. Calcif Tissue Int 35:542\u2013548","journal-title":"Calcif Tissue Int"},{"key":"BF02555900_CR17","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1007\/BF02405105","volume":"35","author":"KW Ng","year":"1983","unstructured":"Ng KW, Partridge NC, Niall M, Martin TJ (1983) Stimulation of DNA synthesis by epidermal growth factor in osteoblast-like cells. Calcif Tissue Int 35:624\u2013628","journal-title":"Calcif Tissue Int"},{"key":"BF02555900_CR18","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/0090-6980(84)90034-0","volume":"28","author":"JHM Feyen","year":"1984","unstructured":"Feyen JHM, van der Wilt G, Moonen P, DiBon A, Nijweide PJ (1984) Stimulation of arachidonic acid metabolism in primary cultures of osteoblast-like cells. Prostaglandins 28:769\u2013781","journal-title":"Prostaglandins"},{"key":"BF02555900_CR19","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1210\/endo-111-6-1810","volume":"111","author":"M Hiramatsu","year":"1982","unstructured":"Hiramatsu M, Kumegawa M, Hatakeyama K, Yajima T, Minami N, Kodama H (1982) Effect of epidermal growth factor on collagen synthesis in osteoblastic cells derived from newborne mouse calvaria. Endocrinology 111:1810\u20131816","journal-title":"Endocrinology"},{"key":"BF02555900_CR20","doi-asserted-by":"crossref","first-page":"15845","DOI":"10.1016\/S0021-9258(18)47665-X","volume":"262","author":"GE Guttierrez","year":"1987","unstructured":"Guttierrez GE, Mundy GR, Derynck R, Hewlett EL, Katz MS (1987) Inhibition of parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by transforming growth factor \u03b1 and epidermal growth factor. J Biol Chem 262:15845\u201315850","journal-title":"J Biol Chem"},{"key":"BF02555900_CR21","doi-asserted-by":"crossref","first-page":"9761","DOI":"10.1016\/S0021-9258(19)81583-1","volume":"263","author":"ME Pereira","year":"1988","unstructured":"Pereira ME, Segaloff DL, Ascoli M. (1988) Inhibition of goandotropin-responsive adenylate cyclase in MA-10 Leyding tumor cells by epidermal growth factor. J Biol Chem 263:9761\u20139766","journal-title":"J Biol Chem"},{"key":"BF02555900_CR22","doi-asserted-by":"crossref","first-page":"2789","DOI":"10.1016\/S0021-9258(18)32787-X","volume":"258","author":"M Knecht","year":"1983","unstructured":"Knecht M, Catt KJ (1983) Modulation of cAMP-mediated differentiation in ovarian granulosa cells by epidermal growth factor and platelet-derived growth factor. J Biol Chem 258:2789\u20132794","journal-title":"J Biol Chem"},{"key":"BF02555900_CR23","doi-asserted-by":"crossref","first-page":"9196","DOI":"10.1016\/S0021-9258(18)48067-2","volume":"262","author":"M Ascoli","year":"1987","unstructured":"Ascoli M, Euffa J, Segaloff DL (1987) Epidermal growth factor activates steroid biosynthesis in cultured Leydig tumor cells without affecting the levels of cAMP and potentiates the activation of steroid biosynthesis by choriogonadotropin and cAMP. J Biol Chem 262:9196\u20139203","journal-title":"J Biol Chem"},{"key":"BF02555900_CR24","first-page":"5888","volume":"47","author":"KVS Rao","year":"1987","unstructured":"Rao KVS, Williams RE, Fox CF (1987) Altered glucocorticoid binding and action in response to epidermal growth factor in HBL 100 cells. Cancer Res 47:5888\u20135893","journal-title":"Cancer Res"},{"key":"BF02555900_CR25","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0021-9258(19)70116-1","volume":"256","author":"M Ascoli","year":"1981","unstructured":"Ascoli M (1981) Regulation of gonadotropin receptors and gonadotropin responses in a clonal strain of Leydig tumor cells by epidermal growth factor. J Biol Chem 256:179\u2013183","journal-title":"J Biol Chem"},{"key":"BF02555900_CR26","first-page":"4308","volume":"43","author":"NC Partridge","year":"1983","unstructured":"Partridge NC, Alcorn D, Michelangeli VP, Ryan G, Martin TJ (1983) Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin. Cancer Res 43:4308\u20134314","journal-title":"Cancer Res"},{"key":"BF02555900_CR27","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/0167-4889(88)90170-X","volume":"970","author":"HAP Pols","year":"1988","unstructured":"Pols HAP, Birkenh\u00e4ger JC, Schilte JP, Visser TJ (1988) Evidence that self-induced metabolism of 1,25-dihydroxyvitamin D3 limits the homologous up-regulation of its receptor in rat osteosarcoma cells. Biochim Biophys Acta 970:122\u2013129","journal-title":"Biochim Biophys Acta"},{"key":"BF02555900_CR28","doi-asserted-by":"crossref","first-page":"10378","DOI":"10.1016\/S0021-9258(19)86719-4","volume":"200","author":"D Feldman","year":"1979","unstructured":"Feldman D, McCain TA, Hirst MA, Chen TL, Colston KW (1979) Characterization of a cytoplasmic receptor-like binder for 1\u03b1, 25-dihydroxycholecalciferol in rat intestinal mucosa. J Biol Chem 200:10378\u201310382","journal-title":"J Biol Chem"},{"key":"BF02555900_CR29","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye staining. Anal Biochem 72:248\u2013254","journal-title":"Anal Biochem"},{"key":"BF02555900_CR30","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/0003-2697(82)90292-5","volume":"122","author":"B Johnson-Wint","year":"1982","unstructured":"Johnson-Wint B, Hollis S (1982) A rapid in situ deoxyribonucleic acid assay for determining cell number in culture and tissue Anal Biochem 122:338\u2013344","journal-title":"Anal Biochem"},{"key":"BF02555900_CR31","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1042\/bj1210561","volume":"121","author":"BL Brown","year":"1971","unstructured":"Brown BL, Albano JDM, Ekins RP, Sgherzi AM (1971) A simple and sensitive saturation assay method for the measurement of adenosine 3\u2032\u22365\u2032-cyclic monophosphate. Biochem J 121:561\u2013562","journal-title":"Biochem J"},{"key":"BF02555900_CR32","first-page":"244","volume-title":"Bone and mineral research, vol 2","author":"GA Rodan","year":"1983","unstructured":"Rodan GA, Rodan SB (1983) Expression of the osteoblastic phenotype. In: Peck WA (ed) Bone and mineral research, vol 2. Elsevier, Amsterdam, pp 244\u2013285"},{"key":"BF02555900_CR33","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0006-291X(87)80539-9","volume":"144","author":"KVS Rao","year":"1987","unstructured":"Rao KVS, Fox CF (1987) Epidermal growth factor stimualtes tyrosine phosphorylation of human glucocorticoid receptor in cultured cells. Biochem Biophys Res Commun 144:512\u2013519","journal-title":"Biochem Biophys Res Commun"},{"key":"BF02555900_CR34","doi-asserted-by":"crossref","first-page":"13469","DOI":"10.1016\/S0021-9258(18)67042-5","volume":"261","author":"CA Nelson","year":"1986","unstructured":"Nelson CA, Seamon KB (1986) Binding of [3H]forskolin to human platelet membranes. J Biol Chem 261:13469\u201313473","journal-title":"J Biol Chem"},{"key":"BF02555900_CR35","doi-asserted-by":"crossref","first-page":"13168","DOI":"10.1016\/S0021-9258(18)45183-6","volume":"262","author":"M Lieberherr","year":"1987","unstructured":"Lieberherr M (1987) Effects of vitamin D3 metabolites on cytosolic-free calcium in confluent mouse osteoblasts. J Biol Chem 262:13168\u201313173","journal-title":"J Biol Chem"},{"key":"BF02555900_CR36","first-page":"177","volume":"4","author":"JPTM Leeuwen van","year":"1989","unstructured":"van Leeuwen JPTM, Bos MP, L\u00f6wik CWGM, Herrmann-Erlee MPM (1989) Effect of parathyroid hormone and parathyroid hormone fragments on the intracellular ionized calcium concentration in an osteoblast cell line. Bone Miner 4:177\u2013188","journal-title":"Bone Miner"},{"key":"BF02555900_CR37","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0143-4160(88)90022-X","volume":"9","author":"JPTM Leeuwen van","year":"1988","unstructured":"van Leeuwen JPTM, Bos MP, Herrmann-Erlee MPM (1988) Independent and interrelated regulation of ornithine decarboxylase by calcium and cAMP in fetal rat osteoblasts. Cell Calcium 9:181\u2013191","journal-title":"Cell Calcium"},{"key":"BF02555900_CR38","doi-asserted-by":"crossref","first-page":"7711","DOI":"10.1016\/S0021-9258(18)47626-0","volume":"262","author":"DT Yamaguchi","year":"1987","unstructured":"Yamaguchi DT, Hahn TJ, Iida-Klein A, Kleeman CR, Muallem S (1987) Parathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. J Biol Chem 262:7711\u20137718","journal-title":"J Biol Chem"},{"key":"BF02555900_CR39","first-page":"E660","volume":"255","author":"R Civitelli","year":"1987","unstructured":"Civitelli R, Reid IR, Westbrook S, Avioli LV, Hruska KA (1987) PTH elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line. Am J Physiol 255:E660-E667","journal-title":"Am J Physiol"},{"key":"BF02555900_CR40","doi-asserted-by":"crossref","first-page":"10745","DOI":"10.1016\/S0021-9258(18)38034-7","volume":"263","author":"DT Yamaguchi","year":"1988","unstructured":"Yamaguchi DT, Hahn TJ, Beeker TG, Kleeman CR, Muallem S (1988) Relationship of cAMP and calcium messenger systems in prostaglandin-stimulated UMR 106 cells. J Biol Chem 263:10745\u201310753","journal-title":"J Biol Chem"},{"key":"BF02555900_CR41","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1042\/bj2520263","volume":"252","author":"RW Farndale","year":"1988","unstructured":"Farndale RW, Sandy JR, Atkinson SJ, Pennington SR, Meghji S, Meikle MC (1988) Parathyroid hormone and prostaglandin E2 stimulate both inositol phosphates and cAMP accumulation in mouse osteoblast cultures. Biochem J 252:263\u2013268","journal-title":"Biochem J"},{"key":"BF02555900_CR42","first-page":"2031","volume":"83","author":"RM Johnson","year":"1986","unstructured":"Johnson RM, Connelly PA, Sisk RB, Pobiner BF, Hewlett EL, Garrison JC (1986) Pertussis toxin or phorbol 12-myristate 13-acetate can distinguish between epidermal growth factor- and angiotensin-stimulated signals in hepatocytes. Proc Natl Acad Sci USA 83:2031\u20132036","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF02555900_CR43","doi-asserted-by":"crossref","first-page":"17285","DOI":"10.1016\/S0021-9258(18)45375-6","volume":"262","author":"RM Johnson","year":"1987","unstructured":"Johnson RM, Garrison JC (1987) Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5- and inositol 1,3,4-trisphosphate in hepatocytes. J Biol Chem 262: 17285\u201317293","journal-title":"J Biol Chem"},{"key":"BF02555900_CR44","doi-asserted-by":"crossref","first-page":"13424","DOI":"10.1016\/S0021-9258(19)76443-6","volume":"262","author":"PM Petkovich","year":"1987","unstructured":"Petkovich PM, Wrana JL, Grigoriadis AE, Heersche JNM, Sodek J (1987) 1,25-dihydroxyvitamin D3 increases epidermal growth factor receptors and transforming growth factor \u03b2-like activity in a bone-derived cell line. J Biol Chem 262:13424\u201313428","journal-title":"J Biol Chem"},{"key":"BF02555900_CR45","first-page":"1015","volume":"46","author":"AS Goustin","year":"1986","unstructured":"Goustin AS, Leof EB, Shipley GD, Moses HL (1986) Growth factors and cancer. Cancer Res 46:1015\u20131029","journal-title":"Cancer Res"},{"key":"BF02555900_CR46","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1126\/science.3859011","volume":"228","author":"KJ Ibbotson","year":"1985","unstructured":"Ibbotson KJ, Twardzik DR, D'Souza SM, Hargreaves TR, Todaro GJ, Mundy GR (1985) Stimulation of bone resorption in vitro by synthetic transforming growth factor-alpha. Science 228:1007\u20131009","journal-title":"Science"}],"container-title":["Calcified Tissue International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02555900.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02555900\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02555900","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,8]],"date-time":"2021-08-08T13:31:59Z","timestamp":1628429519000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02555900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1991,1]]}},"alternative-id":["BF02555900"],"URL":"https:\/\/doi.org\/10.1007\/bf02555900","relation":{},"ISSN":["0171-967X","1432-0827"],"issn-type":[{"value":"0171-967X","type":"print"},{"value":"1432-0827","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,1]]}}}