{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:51:17Z","timestamp":1792119077976,"version":"4.4.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1990,5,1]],"date-time":"1990-05-01T00:00:00Z","timestamp":641520000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Gen Intern Med"],"published-print":{"date-parts":[[1990,5]]},"DOI":"10.1007\/bf02600531","type":"journal-article","created":{"date-parts":[[2007,4,4]],"date-time":"2007-04-04T05:12:19Z","timestamp":1175663539000},"page":"192-197","source":"Crossref","is-referenced-by-count":28,"title":["Recognition and evaluation of red blood cell macrocytosis in the primary care setting"],"prefix":"10.1007","volume":"5","author":[{"given":"Antonette","family":"Wymer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel M.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02600531_CR1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.0954-6820.1981.tb11599.x","volume":"209","author":"FC Breeveld","year":"1981","unstructured":"Breeveld FC, Breger R, van Wermerkerken RK. The clinical significance of macrocytosis. Acta Med Scand. 1981;209:319\u201322.","journal-title":"Acta Med Scand"},{"key":"BF02600531_CR2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1001\/archinte.1979.03630380031013","volume":"139","author":"R Carmel","year":"1979","unstructured":"Carmel R. Macrocytosis, mild anemia and delay in the diagnosis of pernicious anemia. Arch Intern Med. 1979;139:47\u201350.","journal-title":"Arch Intern Med"},{"key":"BF02600531_CR3","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1136\/jcp.31.5.493","volume":"31","author":"RJL Davidson","year":"1978","unstructured":"Davidson RJL, Hamilton PJ. High mean red cell volume: its incidence and significance in routine haematology. J Clin Pathol. 1978;31:493\u20138.","journal-title":"J Clin Pathol"},{"key":"BF02600531_CR4","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1001\/jama.1964.03070130017004","volume":"189","author":"PG Hattersly","year":"1964","unstructured":"Hattersly PG. Macrocytosis of the erythrocytes. JAMA. 1964;189:997\u20139.","journal-title":"JAMA"},{"key":"BF02600531_CR5","doi-asserted-by":"crossref","first-page":"677","DOI":"10.7326\/0003-4819-78-5-677","volume":"78","author":"P McPhedran","year":"1973","unstructured":"McPhedran P, Barnes MG, Weinstein JS, Robertson JS. Interpretation of electronically determined macrocytosis. Ann Intern Med. 1973;78:677\u201383.","journal-title":"Ann Intern Med"},{"key":"BF02600531_CR6","first-page":"908","volume":"117","author":"KL Thong","year":"1977","unstructured":"Thong KL, Hanley SA, Bao BCH, McBride JA. Clinical significance of a high mean corpuscular volume in nonanemic patients. Can Med Assoc J. 1977;117:908\u201310.","journal-title":"Can Med Assoc J"},{"key":"BF02600531_CR7","first-page":"999","volume":"122","author":"AM Shojania","year":"1980","unstructured":"Shojania AM. Problems in the diagnosis and investigation of megaloblastic anemia. Can Med Assoc J. 1980;122:999\u20131003.","journal-title":"Can Med Assoc J"},{"issue":"2","key":"BF02600531_CR8","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1080\/00325481.1979.11715063","volume":"65","author":"P Ward","year":"1979","unstructured":"Ward P. Investigation of macrocytic anemia. Postgrad Med. 1979;65(2):203\u201311.","journal-title":"Postgrad Med"},{"key":"BF02600531_CR9","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1365-2141.1973.tb01746.x","volume":"25","author":"I Charnarin","year":"1973","unstructured":"Charnarin I, England JM, Hoffbrand AV. Significance of large red blood cells. Br J Haematol. 1973;25:351\u20138.","journal-title":"Br J Haematol"},{"key":"BF02600531_CR10","first-page":"1498","volume-title":"Harrison\u2019s textbook of internal medicine","author":"BN Babior","year":"1987","unstructured":"Babior BN, Bunn HF. Megaloblastic anemias. In: Braunwald et al., eds. Harrison\u2019s textbook of internal medicine. 11th ed. New York: McGraw Hill, 1987:1498\u2013504.","edition":"11th ed"},{"key":"BF02600531_CR11","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1182\/blood.V61.4.624.624","volume":"61","author":"J Lindebaum","year":"1983","unstructured":"Lindebaum J. Status of laboratory testing in the diagnosis of megaloblastic anemia. Blood. 1983;61:624\u20137.","journal-title":"Blood"},{"key":"BF02600531_CR12","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1001\/archinte.1982.00340250071012","volume":"142","author":"JL Spivak","year":"1982","unstructured":"Spivak JL. Marked megaloblastic anemia. Arch Intern Med. 1982;142:2111\u20134.","journal-title":"Arch Intern Med"},{"key":"BF02600531_CR13","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1111\/j.1471-0528.1982.tb04657.x","volume":"89","author":"FB Bolton","year":"1982","unstructured":"Bolton FB, Street MJ. Changes in erythrocyte volume and shape in pregnancy. Br J Obstet Gynaecol. 1982;89:1018\u201320.","journal-title":"Br J Obstet Gynaecol"},{"key":"BF02600531_CR14","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/j.1471-0528.1977.tb12634.x","volume":"84","author":"I Chanarin","year":"1977","unstructured":"Chanarin I, McFadyen IR, Kyle R. The physiological macrocytosis of pregnancy. Br J Obstet Gynaecol. 1977;84:504\u20138.","journal-title":"Br J Obstet Gynaecol"},{"key":"BF02600531_CR15","first-page":"3","volume":"52","author":"V Herbert","year":"1985","unstructured":"Herbert V. Megaloblastic anemias, biology of disease. Lab Invest. 1985;52:3\u201319.","journal-title":"Lab Invest"},{"key":"BF02600531_CR16","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0308-2261(21)00498-7","volume":"14","author":"I Chanarin","year":"1985","unstructured":"Chanarin I. Folate and cobalamin. Clin Hematol. 1985;14:629\u201341.","journal-title":"Clin Hematol"},{"key":"BF02600531_CR17","first-page":"65","volume-title":"Medical complications during pregnancy","author":"JG Kelton","year":"1988","unstructured":"Kelton JG, Cruickshank M. Hematologic disorders of pregnancy. In: Burrow GN and Ferris TF, eds. Medical complications during pregnancy. 3rd ed. Philadelphia: W. B. Saunders, 1988;65\u201394.","edition":"3rd ed"},{"key":"BF02600531_CR18","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1136\/bmj.1.5687.16","volume":"1","author":"N Baumslog","year":"1970","unstructured":"Baumslog N, Edelstein T, Metz J. Reduction of incidence of prematurity by folic acid supplementation in pregnancy. Br Med J. 1970;1:16\u20137.","journal-title":"Br Med J"},{"key":"BF02600531_CR19","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/0002-9378(75)90179-9","volume":"122","author":"L Iyengar","year":"1975","unstructured":"Iyengar L, Rajalakshmi K. Effects of folic acid supplement on birth weights of infants. Am J Obstet Gynecol. 1975;122:332\u20136.","journal-title":"Am J Obstet Gynecol"},{"key":"BF02600531_CR20","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1399-0004.1987.tb02809.x","volume":"31","author":"JRW Yates","year":"1987","unstructured":"Yates JRW, Ferguson-Smith MA, Shenken R., et al. Is disordered folate metabolism the basis for the genetic predisposition to neural tube defects? Clin Genet. 1987;31:279\u201387.","journal-title":"Clin Genet"}],"container-title":["Journal of General Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02600531.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02600531\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02600531","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T06:13:52Z","timestamp":1628748832000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02600531"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,5]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1990,5]]}},"alternative-id":["BF02600531"],"URL":"https:\/\/doi.org\/10.1007\/bf02600531","relation":{},"ISSN":["0884-8734","1525-1497"],"issn-type":[{"value":"0884-8734","type":"print"},{"value":"1525-1497","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,5]]}}}