{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:37:32Z","timestamp":1760297852445},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1994,6,1]],"date-time":"1994-06-01T00:00:00Z","timestamp":770428800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1994,6,1]],"date-time":"1994-06-01T00:00:00Z","timestamp":770428800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Mol Neurosci"],"published-print":{"date-parts":[[1994,6]]},"DOI":"10.1007\/bf02736750","type":"journal-article","created":{"date-parts":[[2007,11,6]],"date-time":"2007-11-06T09:57:57Z","timestamp":1194343077000},"page":"83-92","source":"Crossref","is-referenced-by-count":7,"title":["Colorimetric assay for rapid screening of corticotropin releasing factor receptor ligands"],"prefix":"10.1007","volume":"5","author":[{"given":"C. W.","family":"Liaw","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. E.","family":"Grigoriadis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. B.","family":"De Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Oltersdorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02736750_CR1","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1002\/syn.890010610","volume":"1","author":"G. Battaglia","year":"1987","unstructured":"Battaglia G., Webster E. L., and De Souza E. B. (1987) Characterization of corticotropin-releasing factor receptor-mediated adenylate cyclase activity in rat central nervous system.Synapse 1, 572\u2013581.","journal-title":"Synapse"},{"key":"BF02736750_CR2","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1210\/endo-113-2-657","volume":"113","author":"L. M. Bilzikjian","year":"1983","unstructured":"Bilzikjian L. M. and Vale W. W. (1983) Glucocorticoids inhibit corticotropin-releasing factor-induced production of adenosine 3\u2032,5\u2032-monophosphate in cultured anterior pituitary cells.Endocrinology 113, 657\u2013662.","journal-title":"Endocrinology"},{"key":"BF02736750_CR3","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1016\/0896-6273(93)90230-O","volume":"11","author":"C.-P. Chang","year":"1993","unstructured":"Chang C.-P., Pearse R. V. II, O\u2019Connell S., and Rosenfeld M. G. (1993) Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain.Neuron 11, 1187\u20131195.","journal-title":"Neuron"},{"key":"BF02736750_CR4","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/0006-8993(86)90688-8","volume":"381","author":"F. M. Chen","year":"1986","unstructured":"Chen F. M., Bilezikjian L. M., Perrin M. H., Rivier J., and Vale W. (1986) CRF receptor mediated stimulation of adenylate cyclase activity in rat brain.Brain Res. 381, 49\u201357.","journal-title":"Brain Res."},{"key":"BF02736750_CR5","doi-asserted-by":"publisher","first-page":"8967","DOI":"10.1073\/pnas.90.19.8967","volume":"90","author":"R. Chen","year":"1993","unstructured":"Chen R., Lewis K. A., Perrin M. H., and Vale W. W. (1993) Expression cloning of a human corticotropin-releasing factor receptor.Proc. Natl. Acad. Sci. USA 90, 8967\u20138971.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF02736750_CR6","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1210\/endo-119-5-2129","volume":"119","author":"G. V. Childs","year":"1986","unstructured":"Childs G. V., Morell J. L., Niendorf A., and Aguilera G. (1986) Cytochemical studies of corticotropin-releasing factor (CRF) receptors in anterior lobe corticotropes: binding, glucocorticoid regulation, and endocytosis of [biotinyl-ser1] CRF.Endocrinology 119, 2129\u20132142.","journal-title":"Endocrinology"},{"key":"BF02736750_CR7","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.4049\/jimmunol.151.3.1587","volume":"151","author":"L. J. Crofford","year":"1993","unstructured":"Crofford L. J., Sano H., Karalis K., Friedman T. C., Epps H. R., Remmers E. F., Mathern P., Chrousos G. P., and Wilder R. L. (1993) Corticotropin-releasing hormone in synovial fluids and tissues of patients with rheumatoid arthritis and osteoarthritis.J. Immunol. 151, 1587\u20131596.","journal-title":"J. Immunol."},{"key":"BF02736750_CR8","doi-asserted-by":"publisher","first-page":"2555","DOI":"10.1172\/JCI116150","volume":"90","author":"L. J. Crofford","year":"1992","unstructured":"Crofford L. J., Sano H., Karalis K., Webster E. L., Goldmuntz E. A., Chrousos G. P., and Wilder R. L. (1992) Local secretion of corticotropin-releasing hormone in the joints of Lewis rats with inflammatory arthritis.J. Clin. Invest. 90, 2555\u20132564.","journal-title":"J. Clin. Invest."},{"key":"BF02736750_CR9","volume-title":"Corticotropin-Releasing Factor: Basic and Clinical Studies of a Neuropeptide","author":"E. B. De Souza","year":"1990","unstructured":"De Souza E. B. and Nemeroff C. B. (1990)Corticotropin-Releasing Factor: Basic and Clinical Studies of a Neuropeptide. CRC, Boca Raton, FL."},{"key":"BF02736750_CR10","first-page":"145","volume-title":"Handbook of Chemical Neuroanatomy\u2014Neuropeptide Receptors in the CNS, part III","author":"E. B De Souza","year":"1992","unstructured":"De Souza E. B (1992) Corticotropin-releasing hormone receptors, inHandbook of Chemical Neuroanatomy\u2014Neuropeptide Receptors in the CNS, part III (Bjorklund A., Hokfelt T., and Kuhar M. J., eds.) Elsevier, Amsterdam, pp. 145\u2013185."},{"key":"BF02736750_CR11","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/0165-0173(90)90012-D","volume":"15","author":"A. J. Dunn","year":"1990","unstructured":"Dunn A. J. and Berridge C. W. (1990) Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety of stress responses?Brain Res. Rev. 15, 71\u2013100.","journal-title":"Brain Res. Rev."},{"key":"BF02736750_CR12","doi-asserted-by":"publisher","first-page":"3466","DOI":"10.1073\/pnas.79.11.3466","volume":"79","author":"V. Giguere","year":"1982","unstructured":"Giguere V., Labrie F., Cote J., Coy D. H., Sueriras-Diaz J., and Schally A. V. (1982) Stimulation of cAMP accumulation and corticotropin release by synthetic ovine corticotropin-releasing factor in rat anterior pituitary cells: site of glucocorticoid action.Proc. Natl. Acad. Sci. USA 79, 3466\u20133469.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF02736750_CR13","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0196-9781(89)90095-8","volume":"110","author":"D. E. Grigoriadis","year":"1989","unstructured":"Grigoriadis D. E. and De Souza E. B. (1989) Corticotropin-releasing factor (CRF) receptors in intermediate lobe of the pituitary: biochemical characterization and autoradiographic localization.Peptides 110, 179\u2013188.","journal-title":"Peptides"},{"key":"BF02736750_CR14","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1126\/science.1925600","volume":"254","author":"K. Karalis","year":"1991","unstructured":"Karalis K., Sano H., Redwine J., Listwak S., Wilder R. L., and Chrousos G. P. (1991) Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo.Science 254, 421\u2013423.","journal-title":"Science"},{"key":"BF02736750_CR15","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.4049\/jimmunol.142.7.2338","volume":"142","author":"A. Kavelaars","year":"1989","unstructured":"Kavelaars A., Ballieux R. E., and Heijnen C. J. (1989) The role of IL-1 in the corticotropin-releasing factor and arginine-vasopressin-induced secretion of beta-endorphin by human peripheral blood mononuclear cells.J. Immunol. 142, 2338\u20132342.","journal-title":"J. Immunol."},{"key":"BF02736750_CR16","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/1044-7431(91)90063-T","volume":"2","author":"M. K\u00f6nig","year":"1991","unstructured":"K\u00f6nig M., Mahan L. C., Marsh J. W., Fink J. S., and Brownstein M. J. (1991) Method for identifying ligands that bind to cloned Gs-or Gi-coupled receptors.Mol. Cell. Neurosci. 2, 331\u2013337.","journal-title":"Mol. Cell. Neurosci."},{"key":"BF02736750_CR17","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1016\/0024-3205(82)90085-6","volume":"31","author":"F. Labrie","year":"1982","unstructured":"Labrie F., Gagne B., and Lefevre G. (1982) Corticotropin-releasing factor stimulates adenylate cyclase activity in the anterior pituitary gland.Life Sci. 31, 1117\u20131121.","journal-title":"Life Sci."},{"key":"BF02736750_CR18","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/0303-7207(83)90069-2","volume":"30","author":"F. Labrie","year":"1983","unstructured":"Labrie F., Gagne B., Lefevre G., and Meunier H. (1983) CRF stimulates adenylate cyclase activity in the intermediate lobe of the pituitary gland.Mol. Cell. Endocrinol. 30, 347\u2013351.","journal-title":"Mol. Cell. Endocrinol."},{"key":"BF02736750_CR19","first-page":"425","volume":"43","author":"M. J. Owens","year":"1991","unstructured":"Owens M. J. and Nemeroff C. B. (1991) Physiology and pharmacology of corticotropin-releasing factor.Pharmacol. Rev. 43, 425\u2013473.","journal-title":"Pharmacol. Rev."},{"key":"BF02736750_CR20","doi-asserted-by":"publisher","first-page":"3058","DOI":"10.1210\/en.133.6.3058","volume":"133","author":"M. H. Perrin","year":"1993","unstructured":"Perrin M. H., Donaldson C. J., Chen R., Lewis K. A., and Vale W. W. (1993) Cloning and functional expression of a rat brain corticotropin-1 releasing factor (CRF) receptor.Endocrinology 133, 3058\u20133061.","journal-title":"Endocrinology"},{"key":"BF02736750_CR21","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/0304-3940(90)90025-5","volume":"120","author":"V. K. Singh","year":"1990","unstructured":"Singh V. K. and Leu C. S. J. (1990) Enhancing effect of corticotropin-releasing neurohormone on production of interleukin-1 and interleukin-2.Neurosci. Lett. 120, 151\u2013154.","journal-title":"Neurosci. Lett."},{"key":"BF02736750_CR22","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1038\/321881a0","volume":"321","author":"E. M. Smith","year":"1986","unstructured":"Smith E. M., Morill A. C., Meyer W. J., and Blalock J. E. (1986) Corticotropin-releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins.Nature (Lond.) 321, 881,882.","journal-title":"Nature (Lond.)"},{"key":"BF02736750_CR23","first-page":"245","volume":"39","author":"W. Vale","year":"1983","unstructured":"Vale W., Rivier C., Brown M. R., Spiess J., Koob G., Swanson L., Bilezikjian L., Bloom F., and Rivier J. (1983) Chemical and biological characterization of corticotropin-releasing factor.Recent Prog. Horm. Res. 39, 245\u2013270.","journal-title":"Recent Prog. Horm. Res."},{"key":"BF02736750_CR24","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1126\/science.6267699","volume":"213","author":"W. Vale","year":"1981","unstructured":"Vale W., Spiess J., Rivier C., and Rivier J. (1981) Characterization of a 41 residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin.Science 213, 1394\u20131397.","journal-title":"Science"},{"key":"BF02736750_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0014-5793(93)80427-V","volume":"335","author":"N. Vita","year":"1993","unstructured":"Vita N., Laurent P., Lefort S., Chalon P., Lelias J. M., Kaghad M., Le Fur G., Caput D., and Ferrara P. (1993) Primary structure and functional expression of mouse pituitary and human brain corticotropin releasing factor receptor.FEBS Lett. 335, 1\u20135.","journal-title":"FEBS Lett."},{"key":"BF02736750_CR26","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/0196-9781(89)90049-1","volume":"10","author":"E. L. Webster","year":"1989","unstructured":"Webster E. L., Battaglia G., and De Souza E. B. (1989) Functional corticotropin-releasing factor (CRF) receptors in mouse spleen: evidence from adenylate cyclase studies.Peptides 10, 395\u2013401.","journal-title":"Peptides"},{"key":"BF02736750_CR27","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/B978-0-12-482490-4.50016-X","volume-title":"Stress, Neuropeptides and Systemic Disease","author":"E. L. Webster","year":"1991","unstructured":"Webster E. L., Grigoriadis D. E., and De Souza E. B. (1991) Corticotropin-releasing factor receptors in the brain-pituitary-immune axis, inStress, Neuropeptides and Systemic Disease (McCubbin J. A., Kaufmann P. G., and Nemeroff C. B., eds.), Academic, San Diego, pp. 233\u2013260."}],"container-title":["Journal of Molecular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02736750.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF02736750\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02736750","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02736750.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T16:37:57Z","timestamp":1684082277000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF02736750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,6]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1994,6]]}},"alternative-id":["BF02736750"],"URL":"https:\/\/doi.org\/10.1007\/bf02736750","relation":{},"ISSN":["0895-8696","1559-1166"],"issn-type":[{"value":"0895-8696","type":"print"},{"value":"1559-1166","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,6]]}}}