{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:22:57Z","timestamp":1779927777067,"version":"3.53.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1997,12,1]],"date-time":"1997-12-01T00:00:00Z","timestamp":880934400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1997,12,1]],"date-time":"1997-12-01T00:00:00Z","timestamp":880934400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Pancreatol"],"published-print":{"date-parts":[[1997,12]]},"DOI":"10.1007\/bf02788387","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T09:54:47Z","timestamp":1628589287000},"page":"215-220","source":"Crossref","is-referenced-by-count":19,"title":["Pure pancreatic juice from patients with chronic pancreatitis has an impaired antibacterial activity"],"prefix":"10.1007","volume":"22","author":[{"given":"Francesco","family":"Marotta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisao","family":"Tajiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeng-lie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Barreto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osvaldo","family":"Bellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluigi","family":"Barbi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02788387_CR1","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/0928-4680(94)90003-5","volume":"1","author":"F Marotta","year":"1994","unstructured":"Marotta F, Kimura H, Hayakawa K, Nakamura T, Barbi G, Ono K. Patients with chronic pancreatitis have an impaired respiratory burst of monocyte.Pathophysiology 1994; 1: 235\u2013239.","journal-title":"Pathophysiology"},{"key":"BF02788387_CR2","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1007\/BF01296423","volume":"37","author":"JY Sung","year":"1992","unstructured":"Sung JY, Costerton JW, Shaffer EA. Defense system in the biliary tract against bacterial infection.Dig Dis Sci 1992; 37: 689\u2013696.","journal-title":"Dig Dis Sci"},{"key":"BF02788387_CR3","first-page":"87","volume":"35","author":"H Saito","year":"1985","unstructured":"Saito H, Kasajima T, Nagura H. An immunocytochemical study on secretory mechanism of IgA in human pancreas.Acta Pathol Jap 1985; 35: 87\u2013101.","journal-title":"Acta Pathol Jap"},{"key":"BF02788387_CR4","first-page":"187","volume":"86","author":"H Aoyama","year":"1985","unstructured":"Aoyama H. Study on the local immune system of the human pancreas and liver\u2014ultrastructural localization of IgA and secretory component (in Japanese).Nippon Geka Gakkai Zasshi 1985; 86: 187\u2013201.","journal-title":"Nippon Geka Gakkai Zasshi"},{"key":"BF02788387_CR5","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/S0016-5085(85)80009-3","volume":"88","author":"E Rubinstein","year":"1985","unstructured":"Rubinstein E, Mark Z, Haspel J, Ben-Ari G, Dreznik Z, Mirelman D, Tadmor A. Antibacterial activity of the pancreatic fluid.Gastroenterology 1985; 88: 927\u2013932.","journal-title":"Gastroenterology"},{"key":"BF02788387_CR6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1128\/AAC.26.1.35","volume":"26","author":"H Mett","year":"1984","unstructured":"Mett H, Gyr K, Zak O, Vosbeck K. Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial rugs.Antimicrob Agents Chemother 1984; 26: 35\u201338.","journal-title":"Antimicrob Agents Chemother"},{"key":"BF02788387_CR7","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1159\/000168431","volume":"12","author":"S Pierzynowski","year":"1992","unstructured":"Pierzynowski S, Sharma P, Sobczyk J, Garwacki S, Barej W. Influence of feeding regimen and postnatal development stages on antibacterial activity of pancreatic juice.Int J Pancreatol 1992; 12: 121\u2013125.","journal-title":"Int J Pancreatol"},{"key":"BF02788387_CR8","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1093\/ajcn\/32.8.1592","volume":"32","author":"K Gyr","year":"1979","unstructured":"Gyr K, Felsenfeld O, Zimmerli-Ning M. The effect of oral pancreatic enzymes on the intestinal flora of protein deficient vervet monkeys challenged with Vibrio Cholerae.Am J Clin Nutr 1979; 32: 1592\u20131596.","journal-title":"Am J Clin Nutr"},{"key":"BF02788387_CR9","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1439-0396.1985.tb00029.x","volume":"53","author":"S Boisen","year":"1985","unstructured":"Boisen S, Agergaard N, Rotenberg S, Kragelund Z. Effects of gut flora on intestinal activities of trypsin, chymotrypsin, elastase and amylase in growing rats fed purified diets with cellulose pectine or sand.Z Tierphysiol Tiererahgr u Futtermittelkde 1985; 53: 245\u2013254.","journal-title":"Z Tierphysiol Tiererahgr u Futtermittelkde"},{"key":"BF02788387_CR10","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/0016-5085(78)90287-1","volume":"74","author":"K Gyr","year":"1978","unstructured":"Gyr K, Felsenfeld O Zimmerli-Ning M. Effect of oral pancreatic enzymes on the course of cholera in protein-deficient vervet monkeys.Gastroenterology 1978; 74: 511\u2013513.","journal-title":"Gastroenterology"},{"key":"BF02788387_CR11","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1007\/BF02126709","volume":"163","author":"O Felsenfeld","year":"1977","unstructured":"Felsenfeld O, Gyr K. Action of some pancreatic enzymes on Vibrio Cholerae.Med Microbiol Immunol 1977; 163: 53\u201360.","journal-title":"Med Microbiol Immunol"},{"key":"BF02788387_CR12","doi-asserted-by":"publisher","first-page":"313","DOI":"10.3109\/00365527109181126","volume":"6","author":"A Benn","year":"1971","unstructured":"Benn A, Cook WT. Intraluminal pH of duodenum and jejunum in fasting subjects with normal and abnormal gastric and pancreatic functionScand J Gastroenterol 1971; 6: 313\u2013317.","journal-title":"Scand J Gastroenterol"},{"key":"BF02788387_CR13","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1007\/BF01489321","volume":"24","author":"SK Dutta","year":"1979","unstructured":"Dutta SK, Russel RN, Iber FL. Influence of exocrine pancreatic insufficiency on the intraluminal pH of the proximal small intestine.Am J Dig Dis 1979; 24: 529\u2013534.","journal-title":"Am J Dig Dis"},{"key":"BF02788387_CR14","first-page":"99","volume":"82","author":"JHC Ranson","year":"1977","unstructured":"Ranson JHC, Spencer FC. Prevention, diagnosis and treatment of pancreatic abscess.Surgery 1977; 82: 99\u2013106.","journal-title":"Surgery"},{"key":"BF02788387_CR15","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0016-5085(86)90579-2","volume":"91","author":"HG Beger","year":"1986","unstructured":"Beger HG, Bittner R, Block S. Bacterial contamination of pancreatic necrosis.Gastroenterology 1986; 91: 433\u2013438","journal-title":"Gastroenterology"},{"key":"BF02788387_CR16","first-page":"950","volume":"29","author":"SG Gerzof","year":"1984","unstructured":"Gerzof SG, Banks PA, Spechler SJ, Johnson WC, Snider JM, Wetzner SM, Langevin R, Robbins AH. Role of guided percutaneous aspiration in early diagnosis of pancreatic sepsis.Dig Dis Sci 1984; 29: 950\u2013955.","journal-title":"Dig Dis Sci"},{"key":"BF02788387_CR17","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0016-5085(19)31848-7","volume":"73","author":"JA Gregg","year":"1977","unstructured":"Gregg JA. Detection of bacterial infection of the pancreatic ducts in patients with pancreatitis and pancreatic cancer during endoscopic cannulation of the pancreatic duct.Gastroenterology 1977; 73: 1005\u20131007.","journal-title":"Gastroenterology"},{"key":"BF02788387_CR18","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1097\/00006676-199309000-00011","volume":"5","author":"J Iovanna","year":"1993","unstructured":"Iovanna J, Frigerio JM, Dusetti N, Ramare F, Raibaud P, Dagorn JC. Lithostatine, an inhibitor of CaCO3 crystal growth in pancreatic juice, induces bacterial aggregation.Pancreas 1993; 5: 597\u2013601.","journal-title":"Pancreas"},{"key":"BF02788387_CR19","first-page":"G485","volume":"261","author":"J Iovanna","year":"1991","unstructured":"Iovanna J, Michel R, Keim V, Dagorn JC. Pancreatic gene expression is altered during acute experimental pancreatitis in the rat.Am J Physiol 1991; 261: G485-G489.","journal-title":"Am J Physiol"},{"key":"BF02788387_CR20","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/0024-3205(95)02313-5","volume":"58","author":"MV Apte","year":"1996","unstructured":"Apte MV, Norton ID Haber PS, McCaughan GW, Korsten MA, Pirola RC, Wilson JS. Both ethanol and protein deficiency increase messenger RNA levels for pancreatic lithostatine.Life Sci 1996; 58: 485\u2013492.","journal-title":"Life Sci"},{"key":"BF02788387_CR21","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1172\/JCI114128","volume":"84","author":"D Giorgi","year":"1989","unstructured":"Giorgi D, Bernard JP, Rouquier S, Iovanna J, Sarles H, Dagorn JC. Secretory pancreatic stone protein messenger RNA. Nucleotide sequence and expression in chronic calcifying pancreatitis.J Clin Invest 1989; 84: 100\u2013106.","journal-title":"J Clin Invest"}],"container-title":["International journal of pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02788387.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF02788387\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02788387.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T11:36:36Z","timestamp":1657193796000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF02788387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,12]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,12]]}},"alternative-id":["BF02788387"],"URL":"https:\/\/doi.org\/10.1007\/bf02788387","relation":{},"ISSN":["0169-4197","2363-5134"],"issn-type":[{"value":"0169-4197","type":"print"},{"value":"2363-5134","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,12]]}}}