{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T12:37:50Z","timestamp":1790944670443,"version":"4.1.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1987,6,1]],"date-time":"1987-06-01T00:00:00Z","timestamp":549504000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Appl Biochem Biotechnol"],"published-print":{"date-parts":[[1987,6]]},"DOI":"10.1007\/bf02798503","type":"journal-article","created":{"date-parts":[[2007,12,31]],"date-time":"2007-12-31T00:07:01Z","timestamp":1199059621000},"page":"11-24","source":"Crossref","is-referenced-by-count":45,"title":["Synthesis and properties of vinyl monomer\/enzyme conjugates"],"prefix":"10.1007","volume":"15","author":[{"given":"S. G.","family":"Shoemaker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. S.","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Priest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02798503_CR1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/B978-0-12-110950-9.50014-8","volume-title":"Biotechnological Applications of Proteins and Enzymes","author":"H. H. Weetall","year":"1977","unstructured":"Weetall, H. H. (1977), inBiotechnological Applications of Proteins and Enzymes, Bohak, Z., and Sharon, N., eds., Academic, New York, pp. 103\u2013126."},{"key":"BF02798503_CR2","first-page":"394","volume-title":"Chemical Analysis, v. 56: Immobilized Enzymes in Analytical and Clinical Chemistry","author":"P. W. Carr","year":"1980","unstructured":"Carr, P. W., and Bowers, L. D. (1980),Chemical Analysis, v. 56: Immobilized Enzymes in Analytical and Clinical Chemistry, John Wiley, New York, pp. 394\u2013454."},{"key":"BF02798503_CR3","first-page":"95","volume-title":"Hydrogels in Medicine and Pharmacy","author":"W. R. Gombotz","year":"1986","unstructured":"Gombotz, W. R., and Hoffman, A. S., inHydrogels in Medicine and Pharmacy, Vol. I, Peppas, N. A., ed., CRC., Cleveland, OH, (1986) p. 95."},{"key":"BF02798503_CR4","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0076-6879(76)44017-X","volume":"44","author":"D. Jaworek","year":"1976","unstructured":"Jaworek, D., Botsch, H., and Maier, J. (1976),Methods Enzym. 44, 195.","journal-title":"Methods Enzym."},{"key":"BF02798503_CR5","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0168-3659(86)90006-4","volume":"4","author":"L. C. Dong","year":"1986","unstructured":"Dong, L. C., and Hoffman, A. (1986),J. Controlled Rel. 4, 223.","journal-title":"J. Controlled Rel."},{"key":"BF02798503_CR6","first-page":"177","volume":"28","author":"L. C. Dong","year":"1986","unstructured":"Dong, L. C. and Hoffman, A. (1986),Rad. Phys. Chem. 28, 177.","journal-title":"Rad. Phys. Chem."},{"key":"BF02798503_CR7","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1002\/bit.260221105","volume":"22","author":"L. D\u2019Angiuro","year":"1980","unstructured":"D\u2019Angiuro, L., Cremonesi, P., Mazzola, G., Focher, B., and Vecchio, G. (1980),Biotech. Bioeng. 22, 2251.","journal-title":"Biotech. Bioeng."},{"key":"BF02798503_CR8","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1351\/pac198456101351","volume":"46","author":"N. A. Plate","year":"1984","unstructured":"Plate, N. A., Valuev, L. I., and Chupov, V. (1984),Pure and Appl. Chem. 46, 1351.","journal-title":"Pure and Appl. Chem."},{"key":"BF02798503_CR9","unstructured":"Dong, L. C., Monji, N., and Hoffman, A. S., unpublished results."},{"key":"BF02798503_CR10","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/0003-2697(79)90215-X","volume":"95","author":"R. T. Lee","year":"1979","unstructured":"Lee, R. T., Cascio, S., and Lee, Y. (1979),Anal. Biochem. 95, 260.","journal-title":"Anal. Biochem."},{"key":"BF02798503_CR11","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1002\/anie.197208241","volume":"11","author":"H. Schott","year":"1972","unstructured":"Schott, H. (1972),Angew. Chem. Internat. Edit. 11, 824.","journal-title":"Angew. Chem. Internat. Edit."},{"key":"BF02798503_CR12","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1271\/bbb1961.45.2091","volume":"45","author":"Y. Yamazaki","year":"1981","unstructured":"Yamazaki, Y., and Maeda, H. (1981),Agric. Biol. Chem. 45, 2091.","journal-title":"Agric. Biol. Chem."},{"key":"BF02798503_CR13","unstructured":"Cole, C. A., Schreiner, S. M., Monji, N., Priest, J. H., and Hoffman, A. (1986), inReversible Gelation of Polymers, Rupos, P., ed., ACS Symposium Series, in press."},{"key":"BF02798503_CR14","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1021\/bi00678a030","volume":"14","author":"R. L. Schnaar","year":"1975","unstructured":"Schnaar, R. L., and Lee, Y. (1975),Biochemistry 14, 1535.","journal-title":"Biochemistry"},{"key":"BF02798503_CR15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0304-5102(79)85003-8","volume":"6","author":"O. Adalsteinsson","year":"1979","unstructured":"Adalsteinsson, O., Lamotte, A., Baddour, R. F., Colton, C. K., Pollak, A., and Whitesides, G. (1979),J. Mol. Cata. 6, 199.","journal-title":"J. Mol. Cata."},{"key":"BF02798503_CR16","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1002\/anie.197211031","volume":"11","author":"H. G. Batz","year":"1972","unstructured":"Batz, H. G., Franzmann, G., and Ringsdorf, H. (1972),Angew. Chem. internat. Edit. 11, 1103.","journal-title":"Angew. Chem. internat. Edit."},{"key":"BF02798503_CR17","first-page":"435","volume-title":"Pharmacologic Principles of Cancer Treatment","author":"Y. Liu","year":"1982","unstructured":"Liu, Y., and Chabner, B. A. (1982), inPharmacologic Principles of Cancer Treatment, Chabner, B., ed., W. B. Saunders, Philadelphia, PA, pp. 435\u201343."},{"key":"BF02798503_CR18","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1021\/bi00762a013","volume":"11","author":"P. Cuatrecasas","year":"1972","unstructured":"Cuatrecasas, P., and Parikh, I. (1972),Biochemistry 11, 2291.","journal-title":"Biochemistry"},{"key":"BF02798503_CR19","unstructured":"Worthington Biochemical Corporation (1978),Enzymes and Related Biochemicals, Worthington Biochemical, Freehold, NJ, p. 21."},{"key":"BF02798503_CR20","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1093\/oxfordjournals.jbchem.a130690","volume":"76","author":"T. Maita","year":"1974","unstructured":"Maita, T., Moroduma, K., and Matsuda, G. (1974),J. Biochem. 76, 1351.","journal-title":"J. Biochem."},{"key":"BF02798503_CR21","first-page":"49","volume-title":"Immobilized Enzymes, Antigens, Antibodies, and Peptides: Preparation and Characterization","author":"G. P. Royer","year":"1975","unstructured":"Royer, G. P. (1975), inImmobilized Enzymes, Antigens, Antibodies, and Peptides: Preparation and Characterization, Weetall, H. H., ed., Marcel Dekker, New York, pp. 49\u201391."},{"key":"BF02798503_CR22","unstructured":"Milman, I. A., Geiman, I. I., Slavinskaya, V. A., Vina, I. A., and Zhagat, R. (1979),Khim. Prir. Soedin. 707."},{"key":"BF02798503_CR23","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1002\/anie.197105481","volume":"10","author":"G. Talsky","year":"1971","unstructured":"Talsky, G. (1971),Angew. Chem. internat. Edit. 10, 548.","journal-title":"Angew. Chem. internat. Edit."},{"key":"BF02798503_CR24","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0020-1693(00)87438-1","volume":"28","author":"A. J. Charlson","year":"1978","unstructured":"Charlson, A. J., Coman, A. J., Karossi, T. A., Stephens, F. S., Vagg, R. S., and Watton, E. (1978),Inorg. Chim. Acta 28, 217.","journal-title":"Inorg. Chim. Acta"}],"container-title":["Applied Biochemistry and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02798503.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02798503\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02798503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,19]],"date-time":"2019-05-19T03:09:38Z","timestamp":1558235378000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02798503"}},"subtitle":["Conjugation of L-asparaginase with N-succinimidyl acrylate"],"short-title":[],"issued":{"date-parts":[[1987,6]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,6]]}},"alternative-id":["BF02798503"],"URL":"https:\/\/doi.org\/10.1007\/bf02798503","relation":{},"ISSN":["0273-2289","1559-0291"],"issn-type":[{"value":"0273-2289","type":"print"},{"value":"1559-0291","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,6]]}}}