{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T08:03:31Z","timestamp":1697443411318},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1998,2,1]],"date-time":"1998-02-01T00:00:00Z","timestamp":886291200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. China Ser. C.-Life Sci."],"published-print":{"date-parts":[[1998,2]]},"DOI":"10.1007\/bf02882712","type":"journal-article","created":{"date-parts":[[2008,4,4]],"date-time":"2008-04-04T14:05:37Z","timestamp":1207317937000},"page":"99-106","source":"Crossref","is-referenced-by-count":4,"title":["Construction of antisense RNA expression vectors and correction of splicing defect in human \u03b2-globin gene (IVS-2-654 C\u2192T mutant) in HeLa cells"],"prefix":"10.1007","volume":"41","author":[{"given":"Lan","family":"Gong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofeng","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuzheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yitao","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02882712_CR1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00208926","volume":"84","author":"S. Z. Huang","year":"1990","unstructured":"Huang, S. Z., Zhou, X. D., Zhu, H. et al., Detection of \u03b2-thalassemia mutations in the Chinese using amplifies DNA from dried blood specimens,Hum. Genet., 1990, 84: 129.","journal-title":"Hum. Genet."},{"issue":"9","key":"BF02882712_CR2","first-page":"1188","volume":"21","author":"S. Z. Huang","year":"1991","unstructured":"Huang, S. Z., Ren, Z. R., Zeng, Y. T. et al., Study of the RNA splicing defect in the common Chinese \u03b2-thalassemia gene IVS-II nt. 654 C-T by using mRNA\/PCR,Science in China (in Chinese), Ser. B, 1991, 21(9):1188.","journal-title":"Science in China"},{"issue":"1","key":"BF02882712_CR3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1360\/csb1997-42-1-15","volume":"42","author":"L. Gong","year":"1997","unstructured":"Gong, L., Sun, Q., Ren, Z. R. et al., Reversal of aberrant splicing of \u03b2-thalassemic (IVS-2-654 C-T) pre-mRNA by antisense RNAs,Chinese Science Bulletin, 1997, 42(1): 15.","journal-title":"Chinese Science Bulletin"},{"key":"BF02882712_CR4","volume-title":"Molecular Cloning: A Laboratory Manual","author":"J. Sambrook","year":"1989","unstructured":"Sambrook, J., Fritsch, D. F., Maniatis, T.,Molecular Cloning: A Laboratory Manual, New York: Cold Spring Harbor Laboratory, 1989."},{"key":"BF02882712_CR5","doi-asserted-by":"crossref","first-page":"7413","DOI":"10.1073\/pnas.84.21.7413","volume":"84","author":"P. L. Felgner","year":"1987","unstructured":"Felgner, P. L., Gadek, T. R., Holm, M. et al., Lipofection: A highly efficient lipid-mediated DNA-transfection procedure,Proc. Natl. Acad. Sci. USA, 1987, 84: 7413.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF02882712_CR6","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1182\/blood.V78.9.2433.2433","volume":"78","author":"S. Z. Huang","year":"1991","unstructured":"Huang, S. Z., Rodgers, G. R., Zeng, F. Y. et al., Diagnosis of thalassemia using cDNA amplification of circulating erythroid cell mRNA with the polymerase chain reaction,Blood, 1991, 78:2433.","journal-title":"Blood"},{"key":"BF02882712_CR7","volume-title":"The Thalassemia Syndromes","author":"D. J. Weatherall","year":"1981","unstructured":"Weatherall, D. J., Clegg, B.,The Thalassemia Syndromes, Oxford: Blackwell Scienfic Publication, 1981."},{"key":"BF02882712_CR8","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1365-2141.1990.tb07781.x","volume":"75","author":"T. J. H. Huisman","year":"1990","unstructured":"Huisman, T. J. H., Frequency of common \u03b2-thalassemia alleles among different populations: Variability in clinical severity,Brit. J. Haemat., 1990, 75: 454.","journal-title":"Brit. J. Haemat."},{"key":"BF02882712_CR9","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1126\/science.8493530","volume":"260","author":"R. C. Mulligan","year":"1993","unstructured":"Mulligan, R. C., The basic science of gene therapy,Science, 1993, 260: 926.","journal-title":"Science"},{"key":"BF02882712_CR10","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1089\/hum.1996.7.3-275","volume":"7","author":"P. W. Cheng","year":"1996","unstructured":"Cheng, P. W., Receptor ligand-faciliated gene transfer: enhancement of liposome-mediated gene transfer and expression by transferrin,Hum. Gene Therapy, 1996, 7: 275.","journal-title":"Hum. Gene Therapy"},{"key":"BF02882712_CR11","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0092-8674(85)80025-8","volume":"41","author":"M. Boshart","year":"1985","unstructured":"Boshart, M., Weber, F., Jahn, G. et al., A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus,Cell, 1985, 41: 521.","journal-title":"Cell"},{"issue":"2","key":"BF02882712_CR12","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1182\/blood.V74.2.876.876","volume":"74","author":"R. A. Hock","year":"1989","unstructured":"Hock, R. A., Miller, A. D., Osborne, W. R. A., Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines,Blood, 1989, 74(2): 876.","journal-title":"Blood"},{"key":"BF02882712_CR13","doi-asserted-by":"crossref","first-page":"16330","DOI":"10.1016\/S0021-9258(18)42005-4","volume":"267","author":"E. C. Goodwin","year":"1992","unstructured":"Goodwin, E. C., Rottman, F. M., The 3\u2032-flanking sequence of the bovine growth hormone gene contains novel elements required for efficient and accurate polyadenylation,J. Biol. Chem., 1992, 267: 16330.","journal-title":"J. Biol. Chem."},{"issue":"1","key":"BF02882712_CR14","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1074\/jbc.271.1.574","volume":"271","author":"T. Voisin","year":"1996","unstructured":"Voisin, T., Lorinet, A. M., Maoret, J. J. et al., Gi RNA antisense expression demonstrates the exclusive coupling of peptide YY receptors to Gi2 proteins in renal proximal tubule cells,J. Biol. Chem., 1996, 271(1): 574.","journal-title":"J. Biol. Chem."},{"key":"BF02882712_CR15","first-page":"157","volume-title":"Sickle Cell Disease and Thalassaemias; New Trends in Therapy","author":"R. Kole","year":"1995","unstructured":"Kole, R.,Sickle Cell Disease and Thalassaemias; New Trends in Therapy, Colloque Inserm: John Libbey Eurotext Ldt., 1995, 157\u2013162."}],"container-title":["Science in China Series C: Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02882712.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02882712\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02882712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T06:45:14Z","timestamp":1630997114000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02882712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,2]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,2]]}},"alternative-id":["BF02882712"],"URL":"https:\/\/doi.org\/10.1007\/bf02882712","relation":{},"ISSN":["1006-9305","1862-2798"],"issn-type":[{"value":"1006-9305","type":"print"},{"value":"1862-2798","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,2]]}}}