{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:28:35Z","timestamp":1792042115815,"version":"4.4.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1988,12,1]],"date-time":"1988-12-01T00:00:00Z","timestamp":596937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virchows Archiv B Cell Pathol"],"published-print":{"date-parts":[[1988,12]]},"DOI":"10.1007\/bf02890027","type":"journal-article","created":{"date-parts":[[2008,6,26]],"date-time":"2008-06-26T05:16:32Z","timestamp":1214457392000},"page":"277-286","source":"Crossref","is-referenced-by-count":19,"title":["Increase in B-cells in the pancreatic remnant after partial pancreatectomy in pigs"],"prefix":"10.1007","volume":"56","author":[{"given":"M.","family":"L\u00f6hr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Liibbersmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Otremba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Klapdor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Grossner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Kl\u00f6ppel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02890027_CR1","volume-title":"Morphometry","author":"WA Aherne","year":"1982","unstructured":"Aherne WA, Dunnill MS (1982) Morphometry. Edward Arnold, London"},{"key":"BF02890027_CR2","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1172\/JCI110910","volume":"71","author":"S Bonner-Weir","year":"1983","unstructured":"Bonner-Weir S, Trent DF, Weir GC (1983) Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J Clin Invest 71:1544\u20131554","journal-title":"J Clin Invest"},{"key":"BF02890027_CR3","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1210\/jcem-39-2-223","volume":"39","author":"S Cataland","year":"1974","unstructured":"Cataland S, Crockett SE, Brown JC, Mazzaferri EL (1974) Gastric inhibitory peptide (GIP) stimulation by oral glucose in man. J Clin Endocrinol Metab 39:223\u2013228","journal-title":"J Clin Endocrinol Metab"},{"key":"BF02890027_CR4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/BF00339891","volume":"35","author":"W Creutzfeldt","year":"1951","unstructured":"Creutzfeldt W (1951) Experimentelle Untersuchungen \u00fcber die Regenerationsf\u00e4higkeit des Inselapparates (Pankreasresektion am Alloxan-diabetischen Hund). Z Zellforsch 35:47\u201351","journal-title":"Z Zellforsch"},{"key":"BF02890027_CR5","first-page":"43A","volume":"77","author":"R Klapdor","year":"1982","unstructured":"Klapdor R, Grossner D, Berkhoff M, Kl\u00f6ppel G (1982) Pancreatic endocrine function after duct ligation: different behavior of insulin response on bolus injection of glucose, 2 and 60 days after duct ligation in pigs. Digestion 77:43A","journal-title":"Digestion"},{"key":"BF02890027_CR6","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/BF00737292","volume":"403","author":"G Kl\u00f6ppel","year":"1984","unstructured":"Kl\u00f6ppel G, Drenck CR, Oberholzer M, Heitz PU (1984) Morphometric evidence for a striking B-cell reduction at the clinical onset of type 1 diabetes. Virchows Arch [Pathol Anat] 403:441\u2013452","journal-title":"Virchows Arch [Pathol Anat]"},{"key":"BF02890027_CR7","first-page":"110","volume":"4","author":"G Kl\u00f6ppel","year":"1985","unstructured":"Kl\u00f6ppel G, L\u00f6hr M, Habich G, Oberholzer M, Heitz PU (1985) Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited. Surv Synth Pathol Res 4:110\u2013125","journal-title":"Surv Synth Pathol Res"},{"key":"BF02890027_CR8","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2337\/diab.33.7.667","volume":"33","author":"JL Leahy","year":"1984","unstructured":"Leahy JL, Bonner-Weir S, Weir GC (1984) Abnormal glucose regulation of insulin secretion in models of reduced B-cell mass. Diabetes 33:667\u2013673","journal-title":"Diabetes"},{"key":"BF02890027_CR9","first-page":"513","volume":"53","author":"M Lehv","year":"1968","unstructured":"Lehv M, Fitzgerald PJ (1968) Pancreatic acinar cell regeneration. IV. Regeneration after surgical resection. Am J Pathol 53:513\u2013535","journal-title":"Am J Pathol"},{"key":"BF02890027_CR10","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/BF01852074","volume":"157","author":"M Marshall","year":"1972","unstructured":"Marshall M, Lydtin H, Krawietz W, Hagen R (1972) Das Miniaturschwein als Versuchstier in der experimentellen Medizin. Res Exp Med 157:300\u2013325","journal-title":"Res Exp Med"},{"key":"BF02890027_CR11","doi-asserted-by":"crossref","first-page":"238","DOI":"10.2337\/diab.12.3.238","volume":"12","author":"JM Martin","year":"1963","unstructured":"Martin JM, Lacy PE (1963) The prediabetic period in partially pancreatectomized rats. Diabetes 12:238\u2013242","journal-title":"Diabetes"},{"key":"BF02890027_CR12","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1055\/s-0028-1095094","volume":"2","author":"M Marx","year":"1970","unstructured":"Marx M, Schmidt M, Herrmann M, Goberna R (1970) Electron microscopic studies on the existence of the so called \u2018acinarislet cells\u2019 in the regenerating pancreas of the rat. Horm Metab Res 2:204\u2013212","journal-title":"Horm Metab Res"},{"key":"BF02890027_CR13","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0002-9610(82)90077-0","volume":"143","author":"R Mizumoto","year":"1982","unstructured":"Mizumoto R, Kawarda Y, Goshima H, Tamaki H (1982) Carbohydrate metabolism and endocrine function in the pancreas remnant after major pancreatic resection. Am J Surg 143:237\u2013243","journal-title":"Am J Surg"},{"key":"BF02890027_CR14","first-page":"123","volume":"9","author":"M Oberholzer","year":"1987","unstructured":"Oberholzer M, Ettlin RA, Kl\u00f6ppel G, L\u00f6hr M, Heitz PU, Buser M, Mihatsch MJ, Christen H, Marti U (1987) Morphometry and immunocytochemistry. Analyt Quant Histol 9:123\u2013132","journal-title":"Analyt Quant Histol"},{"key":"BF02890027_CR15","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0002-9343(81)90422-8","volume":"70","author":"JM Olefsky","year":"1981","unstructured":"Olefsky JM, Kolterman OG (1981) Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes. Am J Med 70:151\u2013168","journal-title":"Am J Med"},{"key":"BF02890027_CR16","unstructured":"Orland MJ, Chen R, Permutt MA (1984) Response of proinsulin mRNA to pancreatectomy: relationship to glucose tolerance. American Diabetes Association Research Symposium, Mayo Clinic: 24A. Cited from: Weir et al. 1986"},{"key":"BF02890027_CR17","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1159\/000145759","volume":"116","author":"ML Prado","year":"1983","unstructured":"Prado ML, Cruz AR (1983) Adaption of the endocrine tissue of rat pancreas after partial pancreatectomy a morphometric study. Acta Anat 116:346\u2013352","journal-title":"Acta Anat"},{"key":"BF02890027_CR18","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0016-5085(77)80258-8","volume":"72","author":"KW Pearson","year":"1977","unstructured":"Pearson KW, Scott D, Torrance B (1977) Effects of partial pancreatectomy in rats. Gastroenterology 72:469\u2013473","journal-title":"Gastroenterology"},{"key":"BF02890027_CR19","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/BF00251826","volume":"24","author":"J Rahier","year":"1983","unstructured":"Rahier J, Goebbels RM, Henquin JC (1983) Cellular composition of the human diabetic pancreas. Diabetologia 24:366\u2013371","journal-title":"Diabetologia"},{"key":"BF02890027_CR20","volume-title":"Statistische Methoden und ihre Anwendungen","author":"L Sachs","year":"1984","unstructured":"Sachs L (1984) Statistische Methoden und ihre Anwendungen. Springer, Berlin Heidelberg New York Tokyo"},{"key":"BF02890027_CR21","first-page":"75","volume":"9","author":"J Simon","year":"1983","unstructured":"Simon J, Dubois MP (1983) Subtotal pancreatectomy in the chicken: evidence of a diabetic state and effect on the somatostatin cells of the digestive tract. Diab Metab 9:75\u201382","journal-title":"Diab Metab"},{"key":"BF02890027_CR22","doi-asserted-by":"crossref","first-page":"424","DOI":"10.2337\/diab.23.5.424","volume":"23","author":"AM Sun","year":"1974","unstructured":"Sun AM, Coddling JA, Haist RE (1974) A study of glucose tolerance and insulin response in partially depancreatized dogs. Diabetes 23:424\u2013432","journal-title":"Diabetes"},{"key":"BF02890027_CR23","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1172\/JCI111542","volume":"74","author":"WK Ward","year":"1984","unstructured":"Ward WK, Bolgiano DC, McKnight B, Halter JB, Porte D jr (1984) Diminished B-cell secretory capacity in patients with noninsulin-dependent diabetes. J Clin Invest 74:1318\u20131328","journal-title":"J Clin Invest"},{"key":"BF02890027_CR24","volume-title":"Stereological methods. Vol 1 : Practical methods for biological morphometry","author":"ER Weibel","year":"1979","unstructured":"Weibel ER (1979) Stereological methods. Vol 1: Practical methods for biological morphometry. Academic Press, London"},{"key":"BF02890027_CR25","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/dmr.5610020108","volume":"2","author":"GC Weir","year":"1986","unstructured":"Weir GC, Leahy JL, Bonner-Weir S (1986) Experimental reduction of B-cell mass: Implications for the pathogenesis of diabetes. Diab Metab Rev 2:125\u2013161","journal-title":"Diab Metab Rev"},{"key":"BF02890027_CR26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/0002-9610(76)90346-9","volume":"132","author":"H Yasugi","year":"1976","unstructured":"Yasugi H, Mizumoto R, Sakurai H, Honjo I (1976) Changes in carbohydrate metabolism and endocrine function of remnant pancreas after major pancreatic resection. Am J Surg 132:577\u2013581","journal-title":"Am J Surg"},{"key":"BF02890027_CR27","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2337\/diab.33.4.401","volume":"33","author":"Y Yonemura","year":"1984","unstructured":"Yonemura Y, Takashima T, Miwa K, Miyazaki I, Yanamoto H (1984) Amelioration of diabetes mellitus in partially depancreatized rats by poly(ADP-ribose) synthetase inhibitors. Evidence of islet B-cell regeneration. Diabetes 33:401\u2013404","journal-title":"Diabetes"}],"container-title":["Virchows Archiv B Cell Pathology Including Molecular Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02890027.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02890027\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02890027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T16:39:04Z","timestamp":1588783144000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02890027"}},"subtitle":["An immunocytochemical and functional study"],"short-title":[],"issued":{"date-parts":[[1988,12]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1988,12]]}},"alternative-id":["BF02890027"],"URL":"https:\/\/doi.org\/10.1007\/bf02890027","relation":{},"ISSN":["0042-6431"],"issn-type":[{"value":"0042-6431","type":"print"}],"subject":[],"published":{"date-parts":[[1988,12]]}}}