{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:03:16Z","timestamp":1770822196499,"version":"3.50.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1990,1,1]],"date-time":"1990-01-01T00:00:00Z","timestamp":631152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1990,1,1]],"date-time":"1990-01-01T00:00:00Z","timestamp":631152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["La Ricerca Clin. Lab."],"published-print":{"date-parts":[[1990,1]]},"DOI":"10.1007\/bf02910143","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T12:58:53Z","timestamp":1639486733000},"page":"1-10","source":"Crossref","is-referenced-by-count":5,"title":["Immunohistopathogenesis of persistent generalized lymphadenopathy in HIV-positive patients"],"prefix":"10.1007","volume":"20","author":[{"given":"Carlo D.","family":"Baroni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Vitolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Uccini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02910143_CR1","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/S0140-6736(84)90540-3","volume":"ii","author":"J. A. Armstrong","year":"1984","unstructured":"Armstrong J. A., Horne R.: Follicular dendritic cells and virus-like particles in AIDS-related lymphadenopathy \u2014 Lancetii, 370, 1984.","journal-title":"Lancet"},{"key":"BF02910143_CR2","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/j.1365-2559.1986.tb02456.x","volume":"10","author":"C. D. Baroni","year":"1983","unstructured":"Baroni C. D., Pezzella F., Mirolo M., Ruco L. P., Rossi G. B.: Immunohistochemical demonstration of p24 HTLVIII major core protein in different cell types within lymph nodes from patients with lymphadenopathy syndrome (LAS) \u2014 Histopathology10, 5, 1983.","journal-title":"Histopathology"},{"key":"BF02910143_CR3","first-page":"498","volume":"133","author":"C. D. Baroni","year":"1988","unstructured":"Baroni C. D., Pezzella F., Pezzella M., Macchi B., Vitolo D., Uccini S., Ruco L. P.: Expression of HIV in lymph node cells of LAS patients. Immunohistology,in situ hybridization and identification of target cells \u2014 Amer. J. Pathol.133, 498, 1988.","journal-title":"Amer. J. Pathol."},{"key":"BF02910143_CR4","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1111\/j.1365-2559.1985.tb02810.x","volume":"9","author":"C. D. Baroni","year":"1985","unstructured":"Baroni C. D., Pezzella F., Stoppacciaro A., Mirolo M., Pescarmona E., Vitolo D., Cassano A. M., Barsotti P., Nicoletti L., Ruco L. P., Uccini S.: Systemic lymphadenopathy syndrome (LAS) in intravenous drug abusers. Histology, immunochemistry and electron microscopy: pathogenic correlations \u2014 Histopathology9, 1275, 1985.","journal-title":"Histopathology"},{"key":"BF02910143_CR5","unstructured":"Baroni C. D., Uccini S.: Lymph nodes in HIV positive drug abusers with persistent generalized lymphadenopathy: histology, immunohistochemistry and pathogenetic correlations. In:Rotterdam H., Mayer P. R., Sommers S. C., Racz P. (Eds): Progress in AIDS Pathology. Field and Wood, Inc., Philadelphia, PA. (In press)."},{"key":"BF02910143_CR6","unstructured":"Biberfeld P., Porwit-Ksiazek A., Bottiger B., Morfeldt-Masson L., Biberfeld G.: Immunohistopathology of lymph nodes in HTLV-III infected homosexuals with persistent adenopathy or AIDS \u2014 Cancer Res.45 (Suppl.), 4665s, 1985."},{"key":"BF02910143_CR7","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1001\/jama.250.10.1313","volume":"250","author":"R. Brynes","year":"1983","unstructured":"Brynes R., Chan W. C., Spira T. J.: Value of lymph node biopsy in unexplained lymphadenopathy in homosexual men \u2014 J. Amer. med. Ass.250, 1313, 1983.","journal-title":"J. Amer. med. Ass."},{"key":"BF02910143_CR8","first-page":"22","volume":"21","author":"J. Diebold","year":"1988","unstructured":"Diebold J., Audovin J., Le Tourneau A.: Lymphoid tissue changes in HIV infected patients \u2014 Lymphology21, 22, 1988.","journal-title":"Lymphology"},{"key":"BF02910143_CR9","doi-asserted-by":"publisher","first-page":"5199","DOI":"10.1073\/pnas.82.15.5199","volume":"82","author":"F. Di Marzo Veronese","year":"1985","unstructured":"Di Marzo Veronese F., Sarngadharan M. G., Raman R., Markham P. D., Popovic M., Booner A. J., Gallo R. C.: Monoclonal antibody specific for p24, the major core protein for HTLVIII \u2014 Proc. nat. Acad. Sci. (Wash.)82, 5199, 1985.","journal-title":"Proc. nat. Acad. Sci. (Wash.)"},{"key":"BF02910143_CR10","first-page":"185","volume":"309","author":"R. Fernandez","year":"1983","unstructured":"Fernandez R., Mouradian J., Metroka C., Davis J.: Prognostic value of histopathology in persistent generalized lymphadenopathy in homosexual men \u2014 New Engl. J. Med.309, 185, 1983.","journal-title":"New Engl. J. Med."},{"key":"BF02910143_CR11","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1093\/ajcp\/86.6.706","volume":"86","author":"C. F. Garcia","year":"1986","unstructured":"Garcia C. F., Lifson J. D., Engleman E. G., Schmidt D. M., Warnke R. A., Woods G. S.: The immunohistology of the persistent generalized lymphadenopathy syndrome (PGL) \u2014 Amer. J. clin. Pathol.86, 706, 1986.","journal-title":"Amer. J. clin. Pathol."},{"key":"BF02910143_CR12","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1002\/ijc.2910310104","volume":"31","author":"J. Gerdes","year":"1983","unstructured":"Gerdes J., Schwab U., Lemke H., Stein H.: Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation \u2014 Int. J. Cancer31, 13, 1983.","journal-title":"Int. J. Cancer"},{"key":"BF02910143_CR13","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1084\/jem.167.3.914","volume":"167","author":"H. Golding","year":"1988","unstructured":"Golding H., Robey F. A., Gates F. T. III,Linder W., Beining P. R., Hoffman T., Golding B.: Identification of homologous regions in human immunodeficiency virus I gp41 and human MHC class II B1 domain. I. Monoclonal antibodies against the gp41-derived peptide and patients\u2019 sera react with native HLA class II antigens, suggesting a role for autoimmunity in the pathogenesis of acquired immune deficiency syndrome \u2014 J. exp. Med.167, 914, 1988.","journal-title":"J. exp. Med."},{"key":"BF02910143_CR14","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1600-065X.1980.tb01038.x","volume":"53","author":"G. G. B. Klaus","year":"1980","unstructured":"Klaus G. G. B., Humphrey J. H., Kunkl A., Dong-Woth D. W.: The follicular dendritic cell: its role in antigen presentation in the generation of immunological memory \u2014 Immunol. Rev.53, 3, 1980.","journal-title":"Immunol. Rev."},{"key":"BF02910143_CR15","first-page":"353","volume":"43","author":"T. E. Mandell","year":"1981","unstructured":"Mandell T. E., Phipps R. P., Abbot A.: Long-term antigen retention by dendritic cells in the popliteal lymph node of immunized mice \u2014 Immunology43, 353, 1981.","journal-title":"Immunology"},{"key":"BF02910143_CR16","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/j.1600-065X.1980.tb01039.x","volume":"53","author":"T. E. Mandell","year":"1980","unstructured":"Mandell T. E., Phipps R. P., Abbot A., Tew J. G.: The follicular dendritic cell. Long-term antigen retention during immunity \u2014 Immunol. Rev.53, 29, 1980.","journal-title":"Immunol. Rev."},{"issue":"Suppl.","key":"BF02910143_CR17","first-page":"7","volume":"8","author":"A. Ost","year":"1989","unstructured":"Ost A., Baroni C. D., Biberfeld P., Diebold J., Moragas A., Noel H., Pallesen G., Racz P., Schipper M., Tenner-Racz K., van den Tweel J. G.: Lymphadenopathy in HIV infection: histological classification and staging \u2014 Acta pathol. microbiol. immunol. scand.8 (Suppl.), 7, 1989.","journal-title":"Acta pathol. microbiol. immunol. scand."},{"key":"BF02910143_CR18","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1365-3083.1987.tb01049.x","volume":"25","author":"G. Pallesen","year":"1987","unstructured":"Pallesen G., Gerstoft J., Mathiesen L.: Stages in LAV\/HTLVIII lymphadenitis. I. Histological and immunohistological classification \u2014 Scand. J. Immunol.25, 83, 1987.","journal-title":"Scand. J. Immunol."},{"key":"BF02910143_CR19","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1126\/science.6200935","volume":"224","author":"M. Popovic","year":"1984","unstructured":"Popovic M., Sarngadharan M. G., Read E., Gallo R. C.: Detection, isolation and continuous production of cytopathic retroviruses (HTLV3) from patients with AIDS and pre-AIDS \u2014 Science224, 497, 1984.","journal-title":"Science"},{"key":"BF02910143_CR20","first-page":"81","volume":"37","author":"P. Racz","year":"1986","unstructured":"Racz P., Tenner-Racz K., Kahl C., Feller A. C., Kern P., Dietrich M.: Spectrum of morphologic changes of lymph nodes from patients with AIDS or AIDS-related complexes \u2014 Progr. Allergy37, 81, 1986.","journal-title":"Progr. Allergy"},{"key":"BF02910143_CR21","first-page":"17","volume":"66","author":"G. Ragona","year":"1986","unstructured":"Ragona G., Sirianni M. C., Soddu S., Vercelli B., Sebastiani G., Piccoli M., Aiuti F.: Evidence for disregulation in the control of Epstein-Barr virus latency in patients with AIDS-related complex \u2014 Clin. exp. Immunol.66, 17, 1986.","journal-title":"Clin. exp. Immunol."},{"key":"BF02910143_CR22","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/S0046-8177(84)80171-9","volume":"15","author":"J. W. Said","year":"1984","unstructured":"Said J. W., Shintaku I. P., Teitelbaum A., Chien K., Sassoon F.: Distribution of T-cell phenotypic subsets and surface immunoglobulin-bearing lymphocytes in lymph nodes from male homosexuals with persistent generalized adenopathy. An immunohistochemical and ultrastructural study \u2014 Hum. Pathol.15, 785, 1984.","journal-title":"Hum. Pathol."},{"key":"BF02910143_CR23","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1038\/327710a0","volume":"327","author":"R. B. Stricker","year":"1987","unstructured":"Stricker R. B., McHugh T. M., Moody D. J., Morrow W. J. W., Stites D. P., Shuman M. A., Levy J. A.: An AIDS-related cytotoxic autoantibody reacts with a specific antigen on stimulated CD4+ T cells \u2014 Nature (Lond.)327, 710, 1987.","journal-title":"Nature (Lond.)"},{"key":"BF02910143_CR24","first-page":"9","volume":"123","author":"K. Tenner-Racz","year":"1986","unstructured":"Tenner-Racz K., Racz P., Boffil M., Schultz-Meyer A., Dietrich M., Kern P., Weber J., Pinching A. J., Di Marzo Veronese F., Popovic M., Klatzmann D., Gluckman J. C., Janossy G.: HTLVIII\/LAV viral antigens in lymph nodes of homosexual men with persistent generalized lymphadenopathy and AIDS \u2014 Amer. J. Pathol.123, 9, 1986.","journal-title":"Amer. J. Pathol."},{"key":"BF02910143_CR25","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1111\/j.1600-065X.1980.tb01044.x","volume":"53","author":"J. G. Tew","year":"1980","unstructured":"Tew J. G., Phipps R. P., Mandell T. E.: The maintenance and regulation of the humoral immune response. Persisting antigen and the role of follicular antigen-binding dendritic cells as accessory cells \u2014 Immunol. Rev.53, 175, 1980.","journal-title":"Immunol. Rev."},{"key":"BF02910143_CR26","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/BF00737082","volume":"406","author":"M. F. Toccanier","year":"1985","unstructured":"Toccanier M. F., Kapanci Y.: Lymphadenopathy in drug addicts. A study of the distribution of T lymphocyte subsets in the lymph nodes \u2014 Virchows Arch. Abt. A406, 149, 1985.","journal-title":"Virchows Arch. Abt. A"},{"key":"BF02910143_CR27","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1093\/ajcp\/92.6.729","volume":"92","author":"S. Uccini","year":"1989","unstructured":"Uccini S., Monardo F., Vitolo D., Faggioni A., Gradilone A., Aglian\u00f2 A. M., Manzari V., Ruco L. P., Baroni C. D.: HIV and Epstein-Barr virus (EBV) antigens and genome in lymph nodes of HIV positive patients affected by persistent generalized lymphadenopathy \u2014 Amer. J. clin. Pathol.92, 729, 1989.","journal-title":"Amer. J. clin. Pathol."},{"issue":"Suppl.","key":"BF02910143_CR28","first-page":"28","volume":"8","author":"S. Uccini","year":"1989","unstructured":"Uccini S., Vitolo D., Monardo F., Faggioni A., Monarca B., Vitale A., Ruco L. P., Baroni C. D.: Interaction of HIV and EBV at lymphoid tissue level: immunohistochemistry andin situ hybridization \u2014 Acta pathol. microbiol. immunol. scand.8 (Suppl.), 28, 1989.","journal-title":"Acta pathol. microbiol. immunol. scand."}],"container-title":["La Ricerca in Clinica e in Laboratorio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02910143.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF02910143\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02910143.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T12:59:10Z","timestamp":1639486750000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF02910143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["BF02910143"],"URL":"https:\/\/doi.org\/10.1007\/bf02910143","relation":{},"ISSN":["0390-5748"],"issn-type":[{"value":"0390-5748","type":"print"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}