{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:36:09Z","timestamp":1791081369155,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Pharm Res"],"published-print":{"date-parts":[[2006,7]]},"DOI":"10.1007\/bf02969262","type":"journal-article","created":{"date-parts":[[2008,10,30]],"date-time":"2008-10-30T03:59:31Z","timestamp":1225339171000},"page":"541-547","source":"Crossref","is-referenced-by-count":36,"title":["Cytotoxicity and DNA topoisomerase inhibitory activity of constituents isolated from the fruits ofEvodia officinalis"],"prefix":"10.1007","volume":"29","author":[{"given":"Ming-Lu","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Cheol","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong-Soon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi-Hee","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eung Seok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurngdong","family":"Jahng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeun-Wook","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Keun","family":"Son","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02969262_CR1","first-page":"1092","volume":"54","author":"A. Ahmed","year":"1991","unstructured":"Ahmed, A., Ishak, M. S., Micheal, H. N., El-ansari, M. A., and El-Sissi, H. I., Flavonoids ofAsteriscus fraveolens, 54, 1092\u20131093 (1991).","journal-title":"Flavonoids of Asteriscus fraveolens"},{"key":"BF02969262_CR2","first-page":"1012","volume":"61","author":"I. Akira","year":"1988","unstructured":"Akira, I., Hisaom, U., and Takayuki, N., A new indolopyridoquinazoline-type alkaloid fromPhellodendron amurense Callus Tissues.J. Nat. Prod., 61, 1012\u20131014 (1988).","journal-title":"J. Nat. Prod."},{"issue":"3","key":"BF02969262_CR3","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0031-9422(96)00034-9","volume":"42","author":"N. Asano","year":"1996","unstructured":"Asano, N., Kato, A., Kizu, H., and Matsui, K., 1\u03b2-amino-2\u03b1,3\u03b2,5\u03b2-trihydroxycy-cloheptane fromPhysalis alkekengi var.francheti.Phytochemistry, 42(3), 719\u2013721 (1996).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR4","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/0031-9422(80)85136-3","volume":"19","author":"A. Ulubelen","year":"1980","unstructured":"Ulubelen, A., Timmermann, N., and Mabry, T. J., Flavonoids fromBrickellia chlorolepis andB. Dentata., Phytochemistry, 19, 905\u2013908 (1980).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR5","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1021\/jo00208a018","volume":"50","author":"J. Bergman","year":"1985","unstructured":"Bergman, J. and Bergamn S., Strudies of rutaecarpine and related quinazolinocar-boline alkaloids.J. Org. Chem., 50, 1246\u20131255 (1985).","journal-title":"J. Org. Chem."},{"key":"BF02969262_CR6","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1021\/np50023a007","volume":"45","author":"C. A. Buschi","year":"1982","unstructured":"Buschi, C. A. and Pomilio, A. B., Isorhamentin 3-O-robinobioside fromGomphrena Martiana.J. Nat. Prod., 45, 557\u2013559 (1982).","journal-title":"J. Nat. Prod."},{"key":"BF02969262_CR7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1146\/annurev.pa.34.040194.001203","volume":"34","author":"A. Y. Chen","year":"1994","unstructured":"Chen, A. Y. and Liu, L. F., DNA topoisomerase: essential enzymes and lethal targets.Annu. Rev. Pharmacol. Toxicol., 34, 191\u2013218 (1994).","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"BF02969262_CR8","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0305-1978(78)90006-6","volume":"6","author":"D. Crawford","year":"1978","unstructured":"Crawford, D., Flavonoid chemistry ofChenopodium fremontii. Infraspecific variation and systematic implications at the interspecific level.J. Biochem. Syst. Ecol., 6, 189. (1978).","journal-title":"J. Biochem. Syst. Ecol."},{"key":"BF02969262_CR9","first-page":"163","volume":"989","author":"P. D'Arpa","year":"1998","unstructured":"D'Arpa, P. and Liu, L. F., Topoisomerase-targeting antirumor drugs.Biochim. Biophys. Acta., 989, 163\u2013177 (1998).","journal-title":"Biochim. Biophys. Acta."},{"key":"BF02969262_CR10","first-page":"789","volume":"56","author":"M. Fukuda","year":"1996","unstructured":"Fukuda, M., Nishio, K., Kanzawa, F., Ogasawara, H., Ishida, T., Arioka, H., Bojamowski, K., Oka, M., and Saijo, N., Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cells.Cancer Res., 56, 789\u2013793 (1996).","journal-title":"Cancer Res."},{"key":"BF02969262_CR11","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/0031-9422(81)83038-5","volume":"20","author":"J. B. Harborne","year":"1981","unstructured":"Harborne, J. B., Two Gossypetin methyl ethers as ultraviolet patterning guides in the Flowers ofCoronilla valentine.Phytochemistry, 20, 1117\u20131119 (1981).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR12","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0031-9422(97)01130-8","volume":"48","author":"A. Ikuta","year":"1998","unstructured":"Ikuta, A., Nakamura, T., and Urabe, H., Indolopyridoquinazoline, furoquinoline and canthinone type alkaloids fromPhellodendron amurense Callus Tissues.Phytochemistry, 48, 285\u2013291 (1998).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR13","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1021\/np970406y","volume":"61","author":"A. Ikuta","year":"1988","unstructured":"Ikuta, A., Urabe, H., and Nakamura, T., A new indolopyridoquinazoline-type alkaloid fromPhellodendron amurense Callus Tissues.J. Nat. Prod., 61, 1012\u20131014 (1988).","journal-title":"J. Nat. Prod."},{"key":"BF02969262_CR14","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0031-9422(00)00192-8","volume":"54","author":"Y. Ito","year":"2000","unstructured":"Ito, Y., Nishitani, E., Konoshima, T., Takasaki, M., Kozuka, M., and Yoshida, T., Flavonoid and benzophenone glycosides fromColeogyne ramosissima.Phytochemistry, 54, 695\u2013700 (2000).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR15","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1146\/annurev.bi.58.070189.002031","volume":"58","author":"L. F. Liu","year":"1989","unstructured":"Liu, L. F., DNA topoisomerase poisons as antitumor drugs.Annu. Rev. Biochem., 58, 351\u2013375 (1989).","journal-title":"Annu. Rev. Biochem."},{"key":"BF02969262_CR16","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF00685611","volume":"32","author":"Y. Pommier","year":"1993","unstructured":"Pommier, Y., DNA topoisomerase I and II in cancer chemotherapy: update and perspectives.Cancer Chemother. Pharmacol., 32, 103\u2013108 (1993).","journal-title":"Cancer Chemother. Pharmacol."},{"key":"BF02969262_CR17","first-page":"1431","volume":"54","author":"M. Potmesil","year":"1994","unstructured":"Potmesil, M., Camptothecins: from bench research to hospital wards.Cancer Res., 54, 1431\u20131439 (1994).","journal-title":"Cancer Res."},{"key":"BF02969262_CR18","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1093\/jnci\/82.13.1113","volume":"82","author":"L. V. Rubinstein","year":"1990","unstructured":"Rubinstein, L. V., Shoemaker, R. H., Paul, K. D., Simon, R. M., Tosini, S., Skehan, P., Scudiero, D. A., Monks, A., and Boyd, M. R., Comparison ofin vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines.J. Nat. Cancer Inst., 82, 1113\u20131118 (1990).","journal-title":"J. Nat. Cancer Inst."},{"key":"BF02969262_CR19","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1093\/jnci\/85.4.271","volume":"85","author":"W. J. Slichenmyer","year":"1993","unstructured":"Slichenmyer, W. J., Rowinsky, E. K., Donehower, R. C., and Kaufmann, S. H., The current status of camptothecin analogues as antitumor agents.J. Natl. Cancer Inst., 85, 271\u2013291 (1993).","journal-title":"J. Natl. Cancer Inst."},{"key":"BF02969262_CR20","doi-asserted-by":"crossref","first-page":"4453","DOI":"10.1248\/cpb.36.4453","volume":"36","author":"T. Sugimoto","year":"1988","unstructured":"Sugimoto, T., Miyase, T., Kuroyanagi, M., and Ueno, A., Limonoids and quinolone alkaloids from Evodia rutaecarpa Bentham.Chem. Pharm. Bull., 36, 4453\u20134461 (1988).","journal-title":"Chem. Pharm. Bull."},{"key":"BF02969262_CR21","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1016\/0031-9422(84)83046-0","volume":"23","author":"A. Ulubelen","year":"1984","unstructured":"Ulubelen, A., \u00d6ks\u00fcz, S., Halfon, B., Aynehchi, Y., Mabry, T. J., and Matlin, S. A., Flavonoids fromHaplophyllum pedicellatum, H. robustum andH. glabrinum.Phytochemistry, 23, 2941\u20132943 (1984).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR22","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/0031-9422(80)85136-3","volume":"19","author":"A. Ulubelen","year":"1980","unstructured":"Ulubelen, A., Barbara, N., and Tom, J. M., Flavonoids frombrickellia chlorolepis andB. Dentata.Phytochemistry, 19, 905\u2013908 (1980).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR23","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1146\/annurev.bi.65.070196.003223","volume":"65","author":"J. C. Wang","year":"1996","unstructured":"Wang, J. C., DNA topoisomerases.Annu. Rev. Biochem., 65, 635\u2013692 (1996).","journal-title":"Annu. Rev. Biochem."},{"key":"BF02969262_CR24","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1016\/S0031-9422(00)97976-7","volume":"28","author":"Y. Wang","year":"1989","unstructured":"Wang, Y., Hamburger, M., Gueho, J., and Hostettmann, K., Antimicrobial. Flavonoids fromPsiadia trinervia and their methylated and acetylated derivatives.Phytochemistry, 28, 2323\u20132327 (1989).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR25","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0031-9422(03)00205-X","volume":"64","author":"C. Wattanapiromsakul","year":"2003","unstructured":"Wattanapiromsakul, C., Forster, P. I., and Waterman, P. G., Alkaloids and limonoids fromBouchardatia neurococca: systematic significance.Phytochemistry, 64, 609\u2013615 (2003).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR26","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0031-9422(96)00304-4","volume":"43","author":"Y. Q. Tang","year":"1996","unstructured":"Tang, Y. Q., Feng, X. Z., and Huang, L., Quinolone alkaloids fromEvodia futaecarpa.Phytochemistry, 43, 719\u2013722 (1996).","journal-title":"Phytochemistry"},{"key":"BF02969262_CR27","first-page":"127","volume":"11","author":"G. Y. Zuo","year":"2000","unstructured":"Zuo, G. Y., Yang, X. S., and Hao, X. J., Two new indole alkaloids fromEvodia rutaecarpa.Chinese Chem. Lett. 11, 127\u2013128 (2000).","journal-title":"Chinese Chem. Lett."}],"container-title":["Archives of Pharmacal Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02969262.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02969262\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02969262","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T23:29:28Z","timestamp":1558567768000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02969262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["BF02969262"],"URL":"https:\/\/doi.org\/10.1007\/bf02969262","relation":{},"ISSN":["0253-6269","1976-3786"],"issn-type":[{"value":"0253-6269","type":"print"},{"value":"1976-3786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7]]}}}