{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:38:50Z","timestamp":1791081530796,"version":"4.1.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Pharm Res"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1007\/bf02977770","type":"journal-article","created":{"date-parts":[[2008,10,30]],"date-time":"2008-10-30T05:51:17Z","timestamp":1225345877000},"page":"1-7","source":"Crossref","is-referenced-by-count":102,"title":["Antioxidant constituents and a new triterpenoid glycoside fromFlos Lonicerae"],"prefix":"10.1007","volume":"30","author":[{"given":"Chun-Whan","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Ah","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam Sik","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Sue","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF02977770_CR1","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.1016\/0031-9422(92)83678-R","volume":"31","author":"P. K. Agrawal","year":"1992","unstructured":"Agrawal, P. K., NMR spectroscopy in the structural elucidation of oligosaccharides and glycosides.Phytochemistry, 31, 3307\u20133330(1992).","journal-title":"Phytochemistry"},{"key":"BF02977770_CR2","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/1811199a0","volume":"181","author":"M. S. Blois","year":"1958","unstructured":"Blois, M. S., Antioxidant determination by the use of a stable free radical.Nature, 181, 1199\u20131200 (1958).","journal-title":"Nature"},{"key":"BF02977770_CR3","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s003940170020","volume":"40","author":"M. Carbonaro","year":"2001","unstructured":"Carbonaro, M., Grant, G, and Pusztai, A., Evaluation of polyphenol bioavailability in rat small intestine,Eur. J. Nutr., 40, 84\u201390(2001).","journal-title":"Eur. J. Nutr."},{"key":"BF02977770_CR4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.chroma.2005.02.031","volume":"1070","author":"X. Y. Chai","year":"2005","unstructured":"Chai, X. Y., Li, S.-L, and Li, P., Quality evaluation ofFlos Lonicerae through a simultaneous determination of seven saponins by HPLC with ELSD.J. Chromatogr. A, 1070, 43\u201348 (2005).","journal-title":"J. Chromatogr. A"},{"key":"BF02977770_CR5","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0952-3278(92)90088-Z","volume":"45","author":"W.-C. Chang","year":"1992","unstructured":"Chang, W.-C., and Hsu, F.-L., Inhibition of platelet activation and endothelial cell injury by polyphenolic compounds isolated fromLonicera japonicum Thunb.Prost. Leuk. Essen. Fatty Acids, 45, 307\u2013312 (1992).","journal-title":"Prost. Leuk. Essen. Fatty Acids"},{"key":"BF02977770_CR6","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/jssc.200400024","volume":"28","author":"J. Chen","year":"2005","unstructured":"Chen, J., Li, S. L, Li, P., Song, Y, Chai, X.-Y, and Ma, D.-Y., Qualitative and quantitative analysis of active flavonoids inFlos Lonicerae by capillary zone electrophoresis coupled with solid-phase extraction.J. Sep. Sci., 28, 365\u2013372 (2005).","journal-title":"J. Sep. Sci."},{"key":"BF02977770_CR7","first-page":"328","volume":"32","author":"K. C. Chung","year":"1988","unstructured":"Chung, K. C., Kwon, D. Y, Baek, S. H., Kim, S. H., and Chang, H. W., Effects ofLonicerae Flos ethyl acetate fraction on mutagenicity.Yakhak Hoeji, 32, 328\u2013333 (1988).","journal-title":"Yakhak Hoeji"},{"key":"BF02977770_CR8","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1080\/10715760000301341","volume":"33","author":"B. Halliwell","year":"2000","unstructured":"Halliwell, B., Zhao, K. C, and Whiteman, M., The gastrointestinal tract: A major site of antioxidant action?Free Radic. Res., 33, 819\u2013830(2000).","journal-title":"Free Radic. Res."},{"key":"BF02977770_CR9","first-page":"22","volume":"29","author":"D. S. Han","year":"1998","unstructured":"Han, D. S., Baek., K. H., Kim, Y O., Choi, K. E., Kwak, J. S., and Baek, S. H., Development of anticancer agents from Korean medicinal plants, part 6. cytotoxic activity of the ethyl acetate soluble fraction ofLonicerae flos against human oral epitheloid carcinoma cells.Kor. J. Pharmacogn., 29, 22\u201327 (1998).","journal-title":"Kor. J. Pharmacogn."},{"key":"BF02977770_CR10","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/BF02977006","volume":"25","author":"H. A. Jung","year":"2002","unstructured":"Jung, H. A., Kim, A. R., Chung, H. Y, and Choi, J. S.,In vitro antioxidant activity of some selectedPrunus species in Korea.Arch. Pharm. Res., 25, 865\u2013872 (2002).","journal-title":"Arch. Pharm. Res."},{"key":"BF02977770_CR11","first-page":"72","volume":"7","author":"M. J. Jung","year":"2001","unstructured":"Jung, M. J., Chung, H. Y, and Choi, J. S., Antioxidant activity of roasted defatted Perilla seed.Nat. Prod. Sci., 7, 72\u201375 (2001).","journal-title":"Nat. Prod. Sci."},{"key":"BF02977770_CR12","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1007\/BF02980143","volume":"27","author":"H. S. Kang","year":"2004","unstructured":"Kang, H. S., Choi, J. H., Cho, W. K., Park, J. C, and Choi, J. S., A sphingolipid and tyrosinase inhibitors from the fruiting body ofPhellinus linteus.Arch. Pharm. Res., 27, 742\u2013750 (2004).","journal-title":"Arch. Pharm. Res."},{"key":"BF02977770_CR13","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/0040-4020(79)85038-3","volume":"35","author":"R. Kasai","year":"1979","unstructured":"Kasai, R., Okihara, M., Asakawa, J., Mizutani, K., and Tanaka, O.,13C-NMR study of \u03b1- and \u03b2-anomeric pairs of D-manno- pyranosides and L-rhamnopyranosides.Tetradedron, 35, 1427\u20131432(1979).","journal-title":"Tetradedron"},{"key":"BF02977770_CR14","first-page":"37","volume-title":"Illustrated Natural Drugs Encyclopedia","author":"J. G. Kim","year":"1997","unstructured":"Kim, J. G.,Illustrated Natural Drugs Encyclopedia (color edition). Namsandang, Korea, Vol. 1, pp. 37, (1997)."},{"key":"BF02977770_CR15","first-page":"261","volume":"30","author":"J. W. Kim","year":"1999","unstructured":"Kim, J. W., Choi, H. K., Shon, Y H., Lim, J. K., Lee, H. W., and Nam, K. S., Chemopreventive potential ofLonicerae Flos aqua-acupuncture solution.Kor. J. Pharmacol. 30, 261\u2013268 (1999).","journal-title":"Kor. J. Pharmacol."},{"key":"BF02977770_CR16","first-page":"41","volume":"12","author":"Y O. Kim","year":"1996","unstructured":"Kim, Y O., Lee, J. S., Park, K. O., Han, D. S., You, I. S., Kwak, J. S., and Baek, S. H., Development of antitoxic agents from Korean medicinal plants. Part 8: effects of methanol fraction ofLonicerae Flos on the accumulation of cadmium and metallothionein in rats.J. Toxicol. Publ. Health, 12, 41\u201346 (1996).","journal-title":"J. Toxicol. Publ. Health"},{"key":"BF02977770_CR17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0891-5849(94)90138-4","volume":"16","author":"N. W. Kooy","year":"1994","unstructured":"Kooy, N. W., Royall, J. A., Ischiropoulos, H., and Beckman, J. S., Peroxynitrite mediated oxidation of dihydrorhodamine 123.Free Radic. Biol. Med., 16, 149\u2013156 (1994).","journal-title":"Free Radic. Biol. Med."},{"key":"BF02977770_CR18","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0197-0186(90)90025-O","volume":"17","author":"C. P. LeBel","year":"1990","unstructured":"LeBel, C. P. and Bondy, S. C., Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosome.Neurochem. Int., 17, 435\u2013440 (1990).","journal-title":"Neurochem. Int."},{"key":"BF02977770_CR19","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1007\/BF02977002","volume":"25","author":"M. H. Lee","year":"2002","unstructured":"Lee, M. H., Son, Y K., and Han, Y N., Tissue factor inhibitory flavonoids from the fruits ofChaenomeles sinensis.Arch. Pharm. Res., 25, 842\u2013850 (2002).","journal-title":"Arch. Pharm. Res."},{"key":"BF02977770_CR20","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF02979147","volume":"18","author":"S. J. Lee","year":"1995","unstructured":"Lee S. J., Shin E. J., Son K. H., Chang H. W., Kang S. S., and Kim, H. P. 1995. Anti-inflammatory activity of the major constituents ofLonicera japonica.Arch. Pharm. Res., 18, 133\u2013135.","journal-title":"Arch. Pharm. Res."},{"key":"BF02977770_CR21","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1007\/BF02975427","volume":"27","author":"Y S. Lee","year":"2004","unstructured":"Lee, Y S., Lee, H. S., Shin, K. H., Kim, B. K., and Lee, S. H., Constituents of the halophyteSalicornia herbacea.Arch. Pharm. Res., 27, 1034\u20131036 (2004).","journal-title":"Arch. Pharm. Res."},{"key":"BF02977770_CR22","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0021-9673(03)00978-6","volume":"1008","author":"H. J. Li","year":"2003","unstructured":"Li, H. J., Li, P., and Ye, W. C., Determination of five major iridoid glucosides inFlos Lonicerae by high-performance liquid chromatography coupled with evaporative light scattering detection.J. Chromatogr. A, 1008, 167\u2013172 (2003).","journal-title":"J. Chromatogr. A"},{"key":"BF02977770_CR23","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.chroma.2003.11.004","volume":"1026","author":"H. T Lu","year":"2004","unstructured":"Lu, H. T, Jiang, Y, and Chen, R, Application of preparative high-speed counter-current chromatography for separation of chlorogenic acid fromFlos Lonicerae.J. Chromatogr. A, 1026,185\u2013190(2004).","journal-title":"J. Chromatogr. A"},{"key":"BF02977770_CR24","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0006-2952(93)90371-3","volume":"45","author":"I. Morel","year":"1993","unstructured":"Morel, I., Lescoat, G, Cognel, P., Sergent, O., Pasdelop, N., Brissot, P., Cillard, P., and Cillard, J., Antioxidant and iron- chelating activities of the flavonoids catechins, quercetin and diosmetin on iron-loaded rat hepatocyte cultures.Biochem. Pharmacol., 45, 13\u201319 (1993).","journal-title":"Biochem. Pharmacol."},{"key":"BF02977770_CR25","first-page":"61","volume":"7","author":"E. H. Park","year":"1991","unstructured":"Park, E. H. and Han, W. Y, Studies on anti-inflammatory activity of Lonicerae Flos.J. Pharm. Sci., 7, 61\u201369 (1991).","journal-title":"J. Pharm. Sci."},{"key":"BF02977770_CR26","doi-asserted-by":"crossref","first-page":"797","DOI":"10.2174\/0929867013373011","volume":"8","author":"C. A. Rice-Evans","year":"2001","unstructured":"Rice-Evans, C. A., Plavonoid antioxidants.Curr. Med. Chem., 8, 797\u2013807 (2001).","journal-title":"Curr. Med. Chem."},{"key":"BF02977770_CR27","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/0891-5849(95)02227-9","volume":"20","author":"C A. Rice-Evans","year":"1996","unstructured":"Rice-Evans, C A., Miller, N., and Paganga, G, Structure- antioxidant activity relationships of flavonoids and phenolic acids.Free Radic. Biol. Med., 20, 933\u2013956 (1996).","journal-title":"Free Radic. Biol. Med."},{"key":"BF02977770_CR28","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1006\/abbi.1995.1473","volume":"322","author":"N. Salah","year":"1995","unstructured":"Salah, N., Miller, N. J., Paganga, G, Tijburg, L, Bolwell, G P., and Rice-Evans, C. A., Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants.Arch. Biochem. Biophys., 322, 339\u2013346 (1995).","journal-title":"Arch. Biochem. Biophys."},{"key":"BF02977770_CR29","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0031-9422(00)90656-3","volume":"35","author":"K. H. Son","year":"1994","unstructured":"Son, K. H., Jung, K. Y, Chang, H. W., Kim, H. P., and Kang, S. S., Triterpenoid saponins from the aerial parts ofLonicera japonica.Phytochemistry, 35, 1005\u20131008 (1994).","journal-title":"Phytochemistry"}],"container-title":["Archives of Pharmacal Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02977770.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02977770\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02977770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T17:35:47Z","timestamp":1558460147000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02977770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["BF02977770"],"URL":"https:\/\/doi.org\/10.1007\/bf02977770","relation":{},"ISSN":["0253-6269","1976-3786"],"issn-type":[{"value":"0253-6269","type":"print"},{"value":"1976-3786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}