{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:15:34Z","timestamp":1761488134639},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1999,10,1]],"date-time":"1999-10-01T00:00:00Z","timestamp":938736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1999,10,1]],"date-time":"1999-10-01T00:00:00Z","timestamp":938736000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Pharm Res"],"published-print":{"date-parts":[[1999,10]]},"DOI":"10.1007\/bf02979153","type":"journal-article","created":{"date-parts":[[2008,10,30]],"date-time":"2008-10-30T10:39:11Z","timestamp":1225363151000},"source":"Crossref","is-referenced-by-count":8,"title":["Stability and cytotoxicity of Fab-ricin A immunotoxins prepared with water soluble long chain heterobifunctional crosslinking agents"],"prefix":"10.1007","volume":"22","author":[{"given":"Byung Ho","family":"Woo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung Tae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Ok","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang Ro","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeung Whan","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-Seok","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Dong","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang Choon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02979153_CR1","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1042\/bj1730723","volume":"173","author":"J. Carlsson","year":"1978","unstructured":"Carlsson, J., Drevin, H. and Axen, R., Protein thiolation and reversible protein-protein conjugation: N-succinimidyl 3-(2-pyridyldithio) propionate, a new heterobifunctional reagent.Biochem. J., 173, 723\u2013737 (1978).","journal-title":"Biochem. J."},{"key":"BF02979153_CR2","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1021\/bc00027a010","volume":"5","author":"S. F. Carroll","year":"1994","unstructured":"Carroll, S. F., Bernhard, S. L., Coff, D. A., Bauer, R. J., Leach, W. and Kung A.H., Enhanced stability in vitro and in vivo of immunoconjugates prepared with 5-methyl-2-iminothiolane.Bioconj. Chem., 5, 248\u2013256 (1994).","journal-title":"Bioconj. Chem."},{"key":"BF02979153_CR3","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1007\/BF02977530","volume":"16","author":"C. J. Chun","year":"1993","unstructured":"Chun, C. J. and Lee, K. C., Cytotoxicity of anti-CALLA monoclonal antibody conjugates to methotrexate.Arch. Pharm. Res., 16, 347\u2013348 (1993).","journal-title":"Arch. Pharm. Res."},{"key":"BF02979153_CR4","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.4049\/jimmunol.141.8.2837","volume":"141","author":"J. M. Derocq","year":"1988","unstructured":"Derocq, J. M., Casellans, R., Laurent, C., Ravel, S., Vidal, H. and Jansen, F., Comparison of the cytotoxic potency of T101 Fab, F(ab')2 and whole IgC immunotoxins.J. Immunol., 141, 2837\u20132843 (1988).","journal-title":"J. Immunol."},{"key":"BF02979153_CR5","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.4049\/jimmunol.136.8.3103","volume":"136","author":"R. J. Fulton","year":"1986","unstructured":"Fulton, R. J., Uhr, J. W. and Vitetta, E. S., The effect of antibody valency and lysosomotropic amines on the synergy between ricin A chain- and ricin B chain-containing immunotoxins.J. Immunol., 136, 3103\u20133109 (1986).","journal-title":"J. Immunol."},{"key":"BF02979153_CR6","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/0022-1759(93)90335-5","volume":"166","author":"V. Ghetie","year":"1993","unstructured":"Ghetie, V., Swindell, E., Uhr, T. W. and Vitetta, E. S., Purification and properties of immunotoxins containing one vs. Two deglycosylated ricin A chains.J. Immunol. Methods, 166, 117\u2013122 (1993).","journal-title":"J. Immunol. Methods"},{"key":"BF02979153_CR7","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1021\/bc980029g","volume":"10","author":"D. H. Na","year":"1999","unstructured":"Na, D. H., Woo, B. H. and Lee, K. C., Quantitative analysis of derivatized proteins prepared with pyridyl disulfide-containing cross-linkers by HPLC.Bioconj. Chem., 10, 306\u2013310 (1999).","journal-title":"Bioconj. Chem."},{"key":"BF02979153_CR8","first-page":"5924","volume":"47","author":"R E. Thorpe","year":"1987","unstructured":"Thorpe, R E., Wallac, R M., Knowles, R R., Reif, M. G., Brown, A.N.F., Watson, G. J., Knyba, R. E., Wawrzynczak, E. J. and Blakey, D. C., New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.Cancer Res., 47, 5924\u20135931 (1987).","journal-title":"Cancer Res."},{"key":"BF02979153_CR9","first-page":"6396","volume":"48","author":"R E. Thorpe","year":"1988","unstructured":"Thorpe, R E., Wallac, R.M., Knowles, P.P., Relf, M. G., Brown, A.N.F., Watson, G. J., Blakey, D. C. and Newell, D. R., Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A chain and hindered disulfide linkages.Cancer Res., 48, 6396\u20136403 (1988).","journal-title":"Cancer Res."},{"key":"BF02979153_CR10","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1146\/annurev.immunol.14.1.49","volume":"14","author":"G. R. Thrush","year":"1996","unstructured":"Thrush, G. R., Lark, L. R., Clinchy, B. C. and Vitetta, E. S., Immunotoxins: An update.Ann. Rev. Immunol., 14, 49\u201371 (1996).","journal-title":"Ann. Rev. Immunol."},{"key":"BF02979153_CR11","doi-asserted-by":"publisher","first-page":"459","DOI":"10.3109\/10428199309145753","volume":"9","author":"F. M. Uckun","year":"1993","unstructured":"Uckun, F. M., Myers, D. E., Irvin, J. D., Kuebelbeck, V. M., Finnegan, D., Chelstrom, L. M. and Houston, L. L., Effects of the intermolecular toxin-monoclonal antibody linkage on the in vivo stability, immunogenicity and antileukemic activity of B43 (anti-CD19) pokeweed antiviral protein immunotoxin.Leukemia and Lymphoma, 9, 459\u2013476 (1993).","journal-title":"Leukemia and Lymphoma"},{"key":"BF02979153_CR12","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/0022-1759(96)00127-5","volume":"197","author":"D. A. Vallera","year":"1996","unstructured":"Vallera, D. A., Burns, L. J., Frankel, A. E., Sicheneder, A. R., Gunther, R., Fajl-Peczalska, K., Pennell, C. A. and Kersey, J. H., Laboratory preparation of a deglycosylated ricin toxin A chain containing immunotoxin directed against a CD7 T lineage differentiation antigen for phase I human clinical studies involving T cell malignancies.J. Immunol. Methods, 197, 69\u201383 (1996).","journal-title":"J. Immunol. Methods"},{"key":"BF02979153_CR13","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1002\/ijc.2910470123","volume":"47","author":"E. J. Wawarzynczac","year":"1991","unstructured":"Wawarzynczac, E. J., Cumber, A. J., Henry, R. V. and Parnell, G. D., Comparative biochemical, cytotoxic and pharmacokinetic properties of immunotoxins made with native ricin A1 chain, ricin A-, chain and recombinant A chain.Int. J. Cancer., 47, 130\u2013135 (1991).","journal-title":"Int. J. Cancer."},{"key":"BF02979153_CR14","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1007\/BF02979124","volume":"17","author":"B. H. Woo","year":"1994","unstructured":"Woo, B. H., Lee, J. T. and Lee, K. C., Ricin A immunotoxins of IgG and Fab of anti-CALLA monoclonal antibody: Effect of water soluble long-chain SPDP on conjugate yield, immunoselectivity and cytotoxicity.Arch. Pharm. Res., 17, 452\u2013457 (1994).","journal-title":"Arch. Pharm. Res."},{"key":"BF02979153_CR15","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1006\/prep.1998.0880","volume":"13","author":"B. H. Woo","year":"1998","unstructured":"Woo, B. H., Lee, J. T. and Lee, K. C., Purification of Sepharose-unbinding ricin from castor beans (Ricinus communis) by hydroxyapatite chromatography.Protein Expression and Purification, 13, 150\u2013153 (1998).","journal-title":"Protein Expression and Purification"}],"container-title":["Archives of Pharmacal Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02979153.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF02979153\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02979153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02979153.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T20:48:47Z","timestamp":1684615727000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF02979153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,10]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1999,10]]}},"alternative-id":["BF02979153"],"URL":"https:\/\/doi.org\/10.1007\/bf02979153","relation":{},"ISSN":["0253-6269","1976-3786"],"issn-type":[{"value":"0253-6269","type":"print"},{"value":"1976-3786","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,10]]},"article-number":"459"}}