{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T14:03:02Z","timestamp":1776434582110,"version":"3.51.2"},"reference-count":118,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[1990,10,1]],"date-time":"1990-10-01T00:00:00Z","timestamp":654739200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can J Anaesth"],"published-print":{"date-parts":[[1990,10]]},"DOI":"10.1007\/bf03006535","type":"journal-article","created":{"date-parts":[[2009,5,2]],"date-time":"2009-05-02T02:03:19Z","timestamp":1241229799000},"page":"762-777","source":"Crossref","is-referenced-by-count":60,"title":["Brain protection: physiological and pharmacological considerations. Part II: the pharmacology of brain protection"],"prefix":"10.1007","volume":"37","author":[{"given":"Richard","family":"Hall","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Murdoch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF03006535_CR1","first-page":"47","volume":"4","author":"JM Messick","year":"1987","unstructured":"Messick JM Jrs,Milde LM. Brain protection. Advances in Anesthesiology 1987; 4: 47\u201388.","journal-title":"Advances in Anesthesiology"},{"key":"BF03006535_CR2","first-page":"290","volume":"35","author":"WA Aitkenhead","year":"1986","unstructured":"Aitkenhead WA. Cerebral protection. Br J Hosp Med 1986; 35: 290\u20137.","journal-title":"Br J Hosp Med"},{"key":"BF03006535_CR3","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/S0196-0644(85)80058-5","volume":"14","author":"NG Bircher","year":"1985","unstructured":"Bircher NG. Ischemic brain protection. Ann Emerg Med 1985; 14: 784\u20138.","journal-title":"Ann Emerg Med"},{"key":"BF03006535_CR4","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/00000542-198602000-00002","volume":"64","author":"JD Michenfelder","year":"1986","unstructured":"Michenfelder JD. A valid demonstration of barbiturateinduced brain protection in man \u2014at last. Anesthesiology 1986; 64: 140\u20132.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR5","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/00000542-197010000-00013","volume":"33","author":"JD Michenfelder","year":"1970","unstructured":"Michenfelder JD, Theye RA. The effects of anesthesia and hypothermia on canine cerebral ATP and lactate during anoxia produced by decapitation. Anesthesiology 1970; 33: 430\u20139.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR6","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1097\/00000542-198009000-00001","volume":"53","author":"PA Steen","year":"1980","unstructured":"Steen PA, Michenfelder JD. Mechanisms of barbiturate protection. Anesthesiology 1980; 53: 183\u20135.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR7","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1161\/01.STR.10.6.647","volume":"10","author":"NM Branston","year":"1979","unstructured":"Branston NM, Hope DT, Symon L. Barbiturates in focal ischemia of primate cortex: effects on blood flow distribution, evoked potential, and extracellular potassium. Stroke 1979; 10: 647\u201353.","journal-title":"Stroke"},{"key":"BF03006535_CR8","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1161\/01.STR.12.6.858","volume":"12","author":"PJ Feustal","year":"1981","unstructured":"Feustal PJ, Ingvar MC, Severinghaus JW. Cerebral oxygen availability and blood flow during middle cerebral artery occlusion: Effects of pentobarbital. Stroke 1981; 12: 858\u201363.","journal-title":"Stroke"},{"key":"BF03006535_CR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00003246-197801000-00001","volume":"6","author":"LF Marshall","year":"1978","unstructured":"Marshall LF, Shapiro HM, Rauscher A et al. Pentobarbital therapy for intracranial hypertension in metabolic coma: Reye\u2019s Syndrome. Crit Care Med 1978; 6: 1\u20135.","journal-title":"Crit Care Med"},{"key":"BF03006535_CR10","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00000542-198208000-00003","volume":"57","author":"MM Todd","year":"1982","unstructured":"Todd MM, Chadwick HS, Shapiro HM et al. The neurologic effects of thiopental therapy following experimental cardiac arrest in cats. Anesthesiology 1982; 57: 76\u201386.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR11","first-page":"91","volume":"492","author":"HB Demopoulos","year":"1980","unstructured":"Demopoulos HB, Flamm ES, Pietronigro DD et al. The free radical pathology and the microcirculation in the major central nervous system disorders. Acta Physiol Scand Suppl 1980; 492: 91\u2013119.","journal-title":"Acta Physiol Scand Suppl"},{"key":"BF03006535_CR12","first-page":"129","volume":"492","author":"DS Smith","year":"1980","unstructured":"Smith DS, Rehncrona S, Siesjo BK. Barbiturates as protective agents in brain ischemia and as free radical scavengers in vitro. Acta Physiol Scand Suppl 1980; 492: 129\u201334.","journal-title":"Acta Physiol Scand Suppl"},{"key":"BF03006535_CR13","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0735-6757(83)90086-4","volume":"2","author":"EM Nemoto","year":"1983","unstructured":"Nemoto EM, Shiu GK, Nemmer JP et al. Free fatty acid accumulation in the pathogenesis and therapy of ischemic-anoxic brain injury. Am J Emerg Med 1983; 2: 175\u20139.","journal-title":"Am J Emerg Med"},{"key":"BF03006535_CR14","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1111\/j.1471-4159.1978.tb06257.x","volume":"31","author":"PA Steen","year":"1978","unstructured":"Steen PA, Milde JH, Michenfelder JD. Cerebral metabolic and vascular effects of barbiturate therapy following complete global ischemia. J Neurochem 1978; 31: 1317\u201324.","journal-title":"J Neurochem"},{"key":"BF03006535_CR15","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/00000542-197409000-00004","volume":"41","author":"JD Michenfelder","year":"1974","unstructured":"Michenfelder JD. The interdependency of cerebral functional and metabolic effects following massive doses of thiopental in the dog. Anesthesiology 1974; 41: 231\u20136.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR16","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1097\/00000542-197311000-00010","volume":"39","author":"JD Michenfelder","year":"1973","unstructured":"Michenfelder JD, Theye RA. Cerebral protection by thiopental during hypoxia. Anesthesiology 1973; 39: 510\u20137.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR17","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1001\/archneur.1976.00500050031006","volume":"33","author":"JD Michenfelder","year":"1976","unstructured":"Michenfelder JD, Milde JH, Sundt TM Jr. Cerebral protection by barbiturate anesthesia. Use of middle cerebral artery occlusion in Java monkeys. Arch Neurol 1976; 33: 345\u201350.","journal-title":"Arch Neurol"},{"key":"BF03006535_CR18","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1161\/01.STR.6.4.405","volume":"6","author":"JD Michenfelder","year":"1975","unstructured":"Michenfelder JD, Milde JH. Influence of anesthetics on metabolic, functional and pathological responses to regional cerebral ischemia. Stroke 1975; 6: 405\u201310.","journal-title":"Stroke"},{"key":"BF03006535_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/01.STR.5.1.1","volume":"5","author":"AL Smith","year":"1974","unstructured":"Smith AL, Hoff JT, Nielson SL et al. Barbiturate protection in acute focal cerebral ischemia. Stroke 1974; 5: 1\u20137.","journal-title":"Stroke"},{"key":"BF03006535_CR20","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1161\/01.STR.6.1.28","volume":"6","author":"JT Hoff","year":"1975","unstructured":"Hoff JT, Smith AL, Hankinson HL, Nielson SL. Barbiturate protection from cerebral infarction in primates. Stroke 1975; 6: 28\u201333.","journal-title":"Stroke"},{"key":"BF03006535_CR21","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1161\/01.STR.9.1.10","volume":"9","author":"G Corkill","year":"1978","unstructured":"Corkill G, Sivalingam S, Reitan JA et al. Dose dependency of the post-insult protective effect of pentobarbital in the canine experimental stroke model. Stroke 1978; 9: 10\u20132.","journal-title":"Stroke"},{"key":"BF03006535_CR22","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/jcbfm.1982.30","volume":"2","author":"K-A Hossman","year":"1982","unstructured":"Hossman K-A. Treatment of experimental cerebral ischemia. J Cereb Blood Flow Metab 1982; 2: 275\u201397.","journal-title":"J Cereb Blood Flow Metab"},{"key":"BF03006535_CR23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/00000542-198602000-00006","volume":"64","author":"NA Nussmeier","year":"1986","unstructured":"Nussmeier NA, Arlund C, Slogoff S. Neuropsychiatric complications after cardiopulmonary bypass: cerebral protection by a barbiturate. Anesthesiology 1986; 64: 165\u201370.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR24","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1213\/00000539-198211000-00003","volume":"61","author":"S Slogoff","year":"1982","unstructured":"Slogoff S, Girgis KZ, Keats AS. Etiologic factors in neuropsychiatric complications associated with cardiopulmonary bypass. Anesth Analg 1982; 61: 903\u201311.","journal-title":"Anesth Analg"},{"key":"BF03006535_CR25","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0022-5223(19)37448-3","volume":"87","author":"T Aberg","year":"1984","unstructured":"Aberg T, Ronquist G, Tyden H et al. Adverse effects on the brain in cardiac operation as assessed by biochemical, psychometric, and radiologic methods. J Thorac Cardiovasc Surg 1984; 87: 99\u2013105.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BF03006535_CR26","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1097\/00000658-197106010-00020","volume":"173","author":"WH Lee","year":"1971","unstructured":"Lee WH, Brady MP, Rowe JM et al. Effects of extracorporeal circulation upon behavior, personality and brain function. II. Hemodynamic, metabolic and psychometric correlations. Ann Surg 1971; 173: 1013\u201323.","journal-title":"Ann Surg"},{"key":"BF03006535_CR27","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/S0022-5223(19)35442-X","volume":"88","author":"C Aren","year":"1984","unstructured":"Aren C, Blomstrand C, Wikkelso C et al. Hypotension induced by prostacyclin treatment during cardiopulmonary bypass does not increase the risk of cerebral complications. J Thorac Cardiovasc Surg 1984; 88: 748\u201353.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BF03006535_CR28","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0022-5223(19)37952-8","volume":"79","author":"R Kolkka","year":"1980","unstructured":"Kolkka R, Hilberman M. Neurologic dysfunction following cardiac operation with low-flow, low-pressure cardiopulmonary bypass. J Thorac Cardiovasc Surg 1980; 79: 432\u20137.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BF03006535_CR29","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/bja\/52.5.527","volume":"52","author":"JL Seltzer","year":"1980","unstructured":"Seltzer JL, Gerson JI, Allen FB. Comparison of the cardiovascular effects of bolus vs incremental administration of thiopentone. Br J Anaesth 1980; 52: 527\u201330.","journal-title":"Br J Anaesth"},{"key":"BF03006535_CR30","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3171\/jns.1985.62.3.0383","volume":"62","author":"JD Ward","year":"1985","unstructured":"Ward JD, Becker DP, Miller JD et al. Failure of prophylactic barbiturate coma in the treatment of severe head trauma. J Neurosurg 1985; 62: 383\u20138.","journal-title":"J Neurosurg"},{"key":"BF03006535_CR31","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0888-6296(88)90322-5","volume":"2","author":"NA Nussmeier","year":"1988","unstructured":"Nussmeier NA. Barbiturates should be used for brain protection during open heart surgery. J Cardiothorac Anesth 1988; 2: 385\u20139.","journal-title":"J Cardiothorac Anesth"},{"key":"BF03006535_CR32","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0022-5223(19)36089-1","volume":"91","author":"NC Cavarocchi","year":"1986","unstructured":"Cavarocchi NC, Pluth JR, Schaff HV et al. Complement activation during cardiopulmonary bypass: comparison of bubble and membrane oxygenators. J Thorac Cardiovasc Surg 1986: 91: 252\u20138.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BF03006535_CR33","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S0022-5223(19)36021-0","volume":"91","author":"A Aris","year":"1986","unstructured":"Aris A, Solanes H, Camara HL et al. Arterial line filtration during cardiopulmonary bypass. Neurologic, neuropsychologic, and hematologic studies. J Thorac Cardiovasc Surg 1986; 91: 526\u201333.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BF03006535_CR34","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/00000542-198109000-00012","volume":"55","author":"J Astrup","year":"1981","unstructured":"Astrup J, Skovsted P, Gjerris F et al. Increase in extracellular potassium in the brain during circulatory arrest: effects of hypothermia, lidocaine and thiopental. Anesthesiology 1981; 55: 256\u201362.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR35","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/0888-6296(88)90323-7","volume":"2","author":"RL Stevenson","year":"1988","unstructured":"Stevenson RL, Rogers MC. Barbiturates for brain protection during cardiopulmonary bypass: fact or fantasy? J Cardiothorac Anesth 1988; 2: 390\u20132.","journal-title":"J Cardiothorac Anesth"},{"key":"BF03006535_CR36","doi-asserted-by":"crossref","first-page":"H421","DOI":"10.1152\/ajpcell.1985.249.5.C421","volume":"249","author":"JH Donegan","year":"1985","unstructured":"Donegan JH, Traystman RJ, Koehler RC et al. Cerebrovascular hypoxic and autoregulatory responses during reduced brain metabolism. Am J Physiol 1985; 249: H421\u20139.","journal-title":"Am J Physiol"},{"key":"BF03006535_CR37","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1056\/NEJM198602133140701","volume":"314","author":"Brain Resuscitation Clinical Trial I Study Group","year":"1986","unstructured":"Brain Resuscitation Clinical Trial I Study Group: Randomized clinical study of thiopental loading in comatose survivors of cardiac arrest. N Engl J Med 1986; 314: 397\u2013403.","journal-title":"N Engl J Med"},{"key":"BF03006535_CR38","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/00000542-198608000-00027","volume":"65","author":"CA Shanks","year":"1986","unstructured":"Shanks CA, Harter DH, Brunner EA. Barbiturateinduced cerebral protection. An assessment of statistics. Anesthesiology 1986; 65: 232.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR39","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/ana.410060303","volume":"6","author":"MA Rockoff","year":"1979","unstructured":"Rockoff MA, Marshall LF, Shapiro HM. High-dose barbiturate therapy in humans: a clinical review of 60 patients. Ann Neurol 1979; 6: 194\u20139.","journal-title":"Ann Neurol"},{"key":"BF03006535_CR40","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/ana.410060302","volume":"6","author":"JD Miller","year":"1979","unstructured":"Miller JD. Barbiturates and raised intracranial pressure. Ann Neurol 1979; 6: 189\u201393.","journal-title":"Ann Neurol"},{"key":"BF03006535_CR41","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1097\/00000542-198709000-00010","volume":"67","author":"JD Michenfelder","year":"1987","unstructured":"Michenfelder JD, Sundt TM Jr, Fode N et al. Isoflurane when compared to enflurane and halothane decreases the frequency of cerebral ischemia during carotid endarterectomy. Anesthesiology 1987; 67: 336\u201340.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR42","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1097\/00000542-198704000-00002","volume":"66","author":"DG Nehls","year":"1987","unstructured":"Nehls DG, Todd MM, Spetzler RF et al. A comparison of the cerebral protective effects of isoflurane and barbiturates during temporary focal ischemia in primates. Anesthesiology 1987; 66: 453\u201364.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR43","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1213\/00000539-197205000-00025","volume":"51","author":"J Homi","year":"1972","unstructured":"Homi J, Konchigeri HN, Eckenhoff JE et al. A new anesthetic agent \u2014Forane\u00ae: Preliminary observations in man. Anesth Analg 1972; 51: 439\u201347.","journal-title":"Anesth Analg"},{"key":"BF03006535_CR44","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00000542-197107000-00005","volume":"35","author":"WC Stevens","year":"1971","unstructured":"Stevens WC, Cromwell TH, Halsey MJ et al. The cardiovascular effects of a new inhalation anesthetic, Forane, in human volunteers at constant arterial carbon dioxide tension. Anesthesiology 1971; 35: 8\u201316.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR45","first-page":"666","volume":"60","author":"JG Wade","year":"1981","unstructured":"Wade JG, Stevens WC. Isoflurane: an anesthetic for the eighties? Anesth Analg 1981; 60: 666\u201382.","journal-title":"Anesth Analg"},{"key":"BF03006535_CR46","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1213\/00000539-197609000-00021","volume":"55","author":"RR Johnston","year":"1976","unstructured":"Johnston RR, Eger IIEI, Wilson C. A comparative interaction of epinephrine with enflurane, isoflurane, and halothane in man. Anesth Analg 1976; 55: 709\u201312.","journal-title":"Anesth Analg"},{"key":"BF03006535_CR47","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00000542-198307000-00006","volume":"59","author":"LA Newberg","year":"1983","unstructured":"Newberg LA, Michenfelder JD. Cerebral protection by isoflurane during hypoxemia or ischemia. Anesthesiology 1983; 59: 29\u201335","journal-title":"Anesthesiology"},{"key":"BF03006535_CR48","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00000542-198608000-00003","volume":"65","author":"T Maekawa","year":"1986","unstructured":"Maekawa T, Tommasino C, Shapiro HM et al. Local cerebral blood flow and glucose utilization during isoflurane anesthesia in the rat. Anesthesiology 1986; 65: 144\u201351.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR49","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000123897","volume":"38","author":"JK McQueen","year":"1984","unstructured":"McQueen JK, Martin MJ, Fink G. Comparison of the effects of althesin and sodium pentobarbitone on the regional uptake of 2-deoxyglucose by the brain and pituitary gland of the rat: selective effects on pars intermedia. Neuroendocrinology 1984; 38: 237\u201342.","journal-title":"Neuroendocrinology"},{"key":"BF03006535_CR50","first-page":"302","volume-title":"Goodman and Gilman\u2019s: The Pharmacological Basis of Therapeutics","author":"JM Ritchie","year":"1985","unstructured":"Ritchie JM, Greene NM. Local anesthetics. In: Goodman and Gilman\u2019s: The Pharmacological Basis of Therapeutics. Gilman AG, Goodman LS, Rall TW, Murad F. (Eds.). New York. MacMillan Publishing Company 1985; 302\u20134."},{"key":"BF03006535_CR51","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/00000542-198109000-00013","volume":"55","author":"J Astrup","year":"1981","unstructured":"Astrup J, Sorensen PM, Sorensen HR. Inhibition of cerebral oxygen and glucose consumption in the dog by hypothermia, pentobarbital, and lidocaine. Anesthesiology 1981; 55: 263\u20138.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR52","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1227\/00006123-198704000-00006","volume":"20","author":"DE Evans","year":"1987","unstructured":"Evans DE, Kobrine AI. Reduction of experimental intracranial hypertension by lidocaine. Neurosurgery 1987; 20: 542\u20137.","journal-title":"Neurosurgery"},{"key":"BF03006535_CR53","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/00000542-198109000-00014","volume":"55","author":"ML Lescanic","year":"1981","unstructured":"Lescanic ML, Miller ED, DiFazio CA. The effects of lidocaine on the whole body distribution of radioactively labeled microspheres in the conscious rat. Anesthesiology 1981; 55: 269\u201372.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR54","first-page":"339","volume-title":"Goodman and Gilman\u2019s: The Pharmacological Basis of Therapeutics","author":"SL Harvey","year":"1985","unstructured":"Harvey SL. \u201cHypnotics and Sedatives\u201d. In: Goodman and Gilman\u2019s: The Pharmacological Basis of Therapeutics. Gilman AG, Goodman LS, Rail TW, Murad F. (Eds.). 7th ed. New York: MacMillan Publishing Company 1985; 339\u201351.","edition":"7th ed."},{"key":"BF03006535_CR55","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0300-9572(82)90016-8","volume":"10","author":"E Marana","year":"1982","unstructured":"Marana E, Cavaliere F, Beccia F et al. Cerebral protection during extracorporeal circulation. Resuscitation 1982; 10: 89\u2013100.","journal-title":"Resuscitation"},{"key":"BF03006535_CR56","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/00000542-197507000-00029","volume":"43","author":"S Cotev","year":"1975","unstructured":"Cotev S, Shalit MN. Effects of diazepam on cerebral blood flow and oxygen uptake after head injury. Anesthesiology 1975; 43: 117\u201322.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR57","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/0002-9149(85)90623-X","volume":"55","author":"HJ Gelmers","year":"1985","unstructured":"Gelmers HJ. Calcium-channel blockers: effects on cerebral blood flow and potential uses for acute stroke. Am J Cardiol 1985; 55: 144\u20138B.","journal-title":"Am J Cardiol"},{"key":"BF03006535_CR58","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/00000542-198602000-00015","volume":"64","author":"JK Desphande","year":"1986","unstructured":"Desphande JK, Wieloch T. Flunarizine, a calcium entry blocker, ameliorates ischemic brain damage in the rat. Anesthesiology 1986; 64: 215\u201324.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR59","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1161\/01.STR.15.4.666","volume":"15","author":"LA Newberg","year":"1984","unstructured":"Newberg LA, Steen PA, Milde JH, et al. Failure of flunarizine to improve cerebral blood flow or neurologic recovery in a canine model of complete cerebral ischemia. Stroke 1984; 15: 666\u201371.","journal-title":"Stroke"},{"key":"BF03006535_CR60","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0196-0644(83)80640-4","volume":"12","author":"CP Winegar","year":"1983","unstructured":"Winegar CP, Henderson O, White BC et al. Early amelioration of neurologic deficit by lidoflazine after fifteen minutes of cardiopulmonary arrest in dogs. Ann Emerg Med 1983; 12: 471\u20137.","journal-title":"Ann Emerg Med"},{"key":"BF03006535_CR61","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1161\/01.STR.15.3.531","volume":"15","author":"JM Dean","year":"1984","unstructured":"Dean JM, Hoehner PJ, Rogers MC et al. Effect of lidaflazine on cerebral blood flow following twelve minutes total cerebral ischemia. Stroke 1984; 15: 531\u20135.","journal-title":"Stroke"},{"key":"BF03006535_CR62","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0165-6147(85)90052-5","volume":"6","author":"M Spedding","year":"1985","unstructured":"Spedding M. Calcium antagonist subgroups. Trends in Pharmacological Science 1985; 6: 109\u201314.","journal-title":"Trends in Pharmacological Science"},{"key":"BF03006535_CR63","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/jcbfm.1986.56","volume":"6","author":"LN Milde","year":"1986","unstructured":"Milde LN, Milde JH, Michenfelder JD. Delayed treatment with nimodipine improves cerebral blood flow after complete cerebral ischemia in the dog. J Cereb Blood Flow Metab 1986; 6: 332\u20137.","journal-title":"J Cereb Blood Flow Metab"},{"key":"BF03006535_CR64","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/jcbfm.1981.38","volume":"1","author":"AM Harper","year":"1981","unstructured":"Harper AM, Craigen L, Kazda S. Effect of the calcium antagonist, nimodipine, on cerebral blood flow and metabolism in the primate. J Cereb Blood Flow Metab 1981; 1: 349\u201356.","journal-title":"J Cereb Blood Flow Metab"},{"key":"BF03006535_CR65","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1097\/00000542-198811000-00012","volume":"69","author":"IS Kass","year":"1988","unstructured":"Kass IS, Cottrell JE, Chambers G. Magnesium and cobalt, not nimodipine, protect neurons against anoxic damage in the rat hippocampal slice. Anesthesiology 1988; 69: 710\u20135.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR66","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1113\/jphysiol.1982.sp014424","volume":"332","author":"IS Kass","year":"1982","unstructured":"Kass IS, Lipton P. Mechanisms involved in irreversible anoxic damage to the in vitro rat hippocampal slice. J Physiol (Lond) 1982; 332: 459\u201372.","journal-title":"J Physiol (Lond)"},{"key":"BF03006535_CR67","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1126\/science.2432656","volume":"235","author":"RJ Miller","year":"1987","unstructured":"Miller RJ. Multiple calcium channels and neuronal function. Science 1987; 235: 46\u201352.","journal-title":"Science"},{"issue":"72","key":"BF03006535_CR68","first-page":"302","volume":"60","author":"S Kazda","year":"1979","unstructured":"Kazda S, Hoffmeister F, Garthoff B et al. Prevention of the postischemic impaired reperfusion of the brain by nimodipine (BAYe9736). Acta Neurol Scand 60 (Suppl. 1979; 72): 302\u20133.","journal-title":"Acta Neurol Scand"},{"key":"BF03006535_CR69","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1056\/NEJM198801283180402","volume":"318","author":"HJ Gelmers","year":"1988","unstructured":"Gelmers HJ, Goner K, DeWeerdt CJ et al. A controlled trial of nimodipine in acute ischemic stroke. N Engl J Med 1988; 318: 203\u20137.","journal-title":"N Engl J Med"},{"key":"BF03006535_CR70","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/jcbfm.1984.10","volume":"4","author":"PA Steen","year":"1984","unstructured":"Steen PA, Newberg LA, Milde JH et al. Cerebral blood flow and neurologic outcome when nimodipine is given after complete cerebral ischemia in the dog. J Cereb Blood Flow Metab 1984; 4: 82\u20137.","journal-title":"J Cereb Blood Flow Metab"},{"key":"BF03006535_CR71","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/jcbfm.1983.83","volume":"3","author":"M-L Smith","year":"1983","unstructured":"Smith M-L, Kagstrom E, Rosen I et al. Effect of the calcium antagonist nimodipine on the delayed hypoperfusion following incomplete ischemia in the rat. J Cereb Blood Flow Metab 1983; 3: 543\u20136.","journal-title":"J Cereb Blood Flow Metab"},{"key":"BF03006535_CR72","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/BF01728881","volume":"63","author":"L Symon","year":"1982","unstructured":"Symon L, Harris RJ, Branston NM. Calcium ions and calcium antagonists in ischemia. Acta Neurochir 1982; 63: 267\u201375.","journal-title":"Acta Neurochir"},{"key":"BF03006535_CR73","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1213\/00000539-198904000-00003","volume":"68","author":"M Forsman","year":"1989","unstructured":"Forsman M, Aarseth HP, Nordby HK et al. Effects of nimodipine on cerebral blood flow and cerebrospinal fluid pressure after cardiac arrest: correlation with neurologic outcome. Anesth Analg 1989; 68: 436\u201343.","journal-title":"Anesth Analg"},{"key":"BF03006535_CR74","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1056\/NEJM198303173081103","volume":"308","author":"GS Allen","year":"1983","unstructured":"Allen GS, Ahn HS, Preziosi TJ et al. Cerebral arterial spasm \u2014a controlled trial of nimodipine in patients with subarachnoid hemorrhage. N Engl J Med 1983; 308: 619\u201324.","journal-title":"N Engl J Med"},{"key":"BF03006535_CR75","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/01616412.1984.11739660","volume":"6","author":"H Kostron","year":"1984","unstructured":"Kostron H, Twerdy K, Stampfl G et al. Treatment of the traumatic cerebral vasospasm with the calcium channel blocker nimodipine: a preliminary report. Neurol Res 1984; 6: 29\u201332.","journal-title":"Neurol Res"},{"key":"BF03006535_CR76","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3171\/jns.1986.64.4.0617","volume":"64","author":"FB Meyer","year":"1986","unstructured":"Meyer FB, Anderson RE, Yaksh TL et al. Effect of nimodipine on intracellular brain pH, cortical blood flow and EEG in experimental focal cerebral ischemia. J Neurosurg 1986; 64: 617\u201326.","journal-title":"J Neurosurg"},{"key":"BF03006535_CR77","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/S0140-6736(72)92775-4","volume":"2","author":"NT Mathew","year":"1972","unstructured":"Mathew NT, Meyer JS, Rivera VM et al. Double-blind evaluation of glycerol therapy in acute cerebral infarction. Lancet 1972; 2: 1327\u20139.","journal-title":"Lancet"},{"key":"BF03006535_CR78","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1161\/01.STR.13.6.759","volume":"13","author":"RJ Harris","year":"1982","unstructured":"Harris RJ, Branston NM, Symon L et al. The effects of a calcium antagonist, nimodipine, upon physiological responses of the cerebral vasculature and its possible influence upon focal cerebral ischemia. Stroke 1982; 13: 759\u201366.","journal-title":"Stroke"},{"key":"BF03006535_CR79","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/jcbfm.1981.21","volume":"1","author":"RJ Harris","year":"1981","unstructured":"Harris RJ, Symon L, Branston NM et al. Changes in extracellular calcium activity in cerebral ischemia. J. Cereb Blood Flow Metab 1981; 1: 203\u201310.","journal-title":"J. Cereb Blood Flow Metab"},{"key":"BF03006535_CR80","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1097\/00000542-198811000-00011","volume":"69","author":"J Church","year":"1988","unstructured":"Church J, Zeman S, Lodge D. The neuroprotective action of ketamine and MK-801 after transient cerebral ischemia in rats. Anesthesiology 1988; 69: 702\u20139.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR81","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1476-5381.1983.tb11031.x","volume":"79","author":"NA Anis","year":"1983","unstructured":"Anis NA, Berry SC, Burton NR et al. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. Br J Pharmacol 1983; 79: 565\u201375.","journal-title":"Br J Pharmacol"},{"key":"BF03006535_CR82","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1093\/bja\/44.11.1200","volume":"44","author":"HM Shapiro","year":"1972","unstructured":"Shapiro HM, Wyte SR, Harris AB. Ketamine anaesthesia in patients with intracranial pathology. Br J Anaesth 1972; 44: 1200\u20134.","journal-title":"Br J Anaesth"},{"key":"BF03006535_CR83","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1093\/bja\/44.12.1298","volume":"44","author":"JM Gibbs","year":"1972","unstructured":"Gibbs JM. The effect of intravenous ketamine on cerebrospinal fluid pressure. Br J Anesth 1972; 44: 1298\u2013301.","journal-title":"Br J Anesth"},{"key":"BF03006535_CR84","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1097\/00000542-198004000-00009","volume":"52","author":"SR Nelson","year":"1980","unstructured":"Nelson SR, Howard RB, Cross RS et al. Ketamineinduced changes in regional glucose utilization in the rat brain. Anesthesiology 1980; 52: 330\u20134.","journal-title":"Anesthesiology"},{"key":"BF03006535_CR85","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1097\/00003246-197910000-00005","volume":"7","author":"JA Aldrete","year":"1979","unstructured":"Aldrete JA, Romo-Salas F, Jankovsky L et al. Effect of pretreatment with thiopental and phenytoin on postischemic brain damage in rabbits. Crit Care Med 1979; 7: 466\u201371.","journal-title":"Crit Care Med"},{"key":"BF03006535_CR86","first-page":"165","volume":"58","author":"JP Cullen","year":"1979","unstructured":"Cullen JP, Aldrete JA, Jankovsky L et al. Protective action of phenytoin in cerebral ischemia. Anesth Analg 1979; 58: 165\u20139.","journal-title":"Anesth Analg"},{"key":"BF03006535_CR87","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1097\/00003246-198106000-00008","volume":"9","author":"JA Aldrete","year":"1981","unstructured":"Aldrete JA, Romo-Salas F, Mazzia VDB et al. Phenytoin for brain resuscitation after cardiac arrest. An uncontrolled clinical trial. Crit Care Med 1981; 9: 474\u20137.","journal-title":"Crit Care Med"},{"key":"BF03006535_CR88","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1161\/01.STR.11.4.377","volume":"11","author":"AA Artru","year":"1980","unstructured":"Artru AA, Michenfelder JD. Cerebral protective metabolic, and vascular effects of phenytoin. Stroke 1980; 11: 377\u201382.","journal-title":"Stroke"},{"key":"BF03006535_CR89","first-page":"41","volume":"60","author":"AA Artru","year":"1981","unstructured":"Artru AA, Michenfelder JD. Anoxic cerebral potassium accumulation reduced by phenytoin: mechanism of cerebral protection? Anesth Analg 1981; 60: 41\u20135.","journal-title":"Anesth Analg"},{"key":"BF03006535_CR90","first-page":"1459","volume-title":"Goodman and Gilman\u2019s \u201cThe Pharmacological Basis of Therapeutics.\u201d","author":"RC Haynes","year":"1985","unstructured":"Haynes RC Jr, Murad F. Adrenocorticotropic hormone; adrenocortical steroids and their synthetic analogs; inhibitors of adrenocortical steroid biosynthesis. In: Goodman and Gilman\u2019s \u201cThe Pharmacological Basis of Therapeutics.\u201d Goodman Gilman A, Goodman LS, Rall TW, Murad F (Eds.). 7th Ed. New York: MacMillan Publishing Company: 1985; 1459\u201389.","edition":"7th Ed"},{"key":"BF03006535_CR91","first-page":"271","volume":"102","author":"JL Farber","year":"1981","unstructured":"Farber JL, Chien KR, Mittnacht S Jr. The pathogenesis of irreversible cell injury in ischemia. Am J Pathol 1981; 102: 271\u201381.","journal-title":"Am J Pathol"},{"key":"BF03006535_CR92","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/287147a0","volume":"287","author":"GJ Blackwell","year":"1980","unstructured":"Blackwell GJ, Carnuccio R, Di Rosa M et al. Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids. Nature 1980; 287: 147\u20139.","journal-title":"Nature"},{"key":"BF03006535_CR93","first-page":"185","volume":"86","author":"GB Ryan","year":"1977","unstructured":"Ryan GB, Majno G. Acute inflammation: a review. Am J Pathol 1977; 86: 185\u2013276.","journal-title":"Am J Pathol"},{"key":"BF03006535_CR94","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1038\/273552a0","volume":"273","author":"A Danon","year":"1978","unstructured":"Danon A, Assouline G. Inhibition of prostaglandin biosynthesis by corticosteroids requires RNA and protein synthesis. Nature 1978; 273: 552\u20134.","journal-title":"Nature"},{"key":"BF03006535_CR95","unstructured":"Coote PR, DiRosa M, Flower RJ et al. Detection and isolation of a steroid-induced antiphospholipase protein of high molecular weight. Br J Pharmacol 1983; 80: 597P."},{"key":"BF03006535_CR96","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0006-291X(82)91588-1","volume":"109","author":"F Hirata","year":"1982","unstructured":"Hirata F, Notsu Y, Iwata M et al. Identification of several species of phospholipase inhibitory protein(s) by radioimmunoassay for lipomodulin. Biochem Biophys Res Commun 1982; 109: 223\u201330.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF03006535_CR97","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1161\/01.STR.10.1.68","volume":"10","author":"DC Anderson","year":"1979","unstructured":"Anderson DC, Cranford RE. Corticosteroids in ischemic stroke. Stroke 1979; 10: 68\u201371.","journal-title":"Stroke"},{"key":"BF03006535_CR98","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1001\/archneur.1969.00480080107013","volume":"20","author":"HM Pappius","year":"1969","unstructured":"Pappius HM, McCann WP. Effects of steroids on cerebral edema in cats. Arch Neurol 1969; 20: 207\u201316.","journal-title":"Arch Neurol"},{"key":"BF03006535_CR99","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1001\/archneur.1963.00460120021002","volume":"9","author":"F Plum","year":"1963","unstructured":"Plum F, Alvord EC Jr, Posner JB. Effect of steroids on experimental cerebral infarction. Arch Neurol 1963; 9: 571\u20133.","journal-title":"Arch Neurol"},{"key":"BF03006535_CR100","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/978-3-642-65448-0","volume-title":"Steroids and Brain Edema","author":"HJ Reulen","year":"1972","unstructured":"Reulen HJ. Steroids and Brain Edema. New York. Springer Verlag Co. 1972: 33\u20139"},{"key":"BF03006535_CR101","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/00005072-196804000-00007","volume":"27","author":"RL Rovit","year":"1968","unstructured":"Rovit RL, Hagen R. Steroids and cerebral edema: the effect of glucocorticords on abnormal capillary permeability following cerebral injury in cats. J Neuropathol Exp Neurol 1968; 27: 277\u201398.","journal-title":"J Neuropathol Exp Neurol"},{"key":"BF03006535_CR102","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/BF01982620","volume":"17","author":"M Koltai","year":"1985","unstructured":"Koltai M, Tosaki A, Lepran I et al. Glucocorticoids in myocardial and cerebral infarction. Agents Actions 1985; 17: 278\u201383.","journal-title":"Agents Actions"},{"key":"BF03006535_CR103","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1212\/WNL.22.4.377","volume":"22","author":"BM Patten","year":"1972","unstructured":"Patten BM, Mendell J, Bruun B et al. Double-blind study of the effect of dexamethasone on acute stroke. Neurology 1972; 22: 377\u201383.","journal-title":"Neurology"},{"key":"BF03006535_CR104","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1172\/JCI109433","volume":"64","author":"WM Pardridge","year":"1979","unstructured":"Pardridge WM, Mietus LJ. Transport of steroid hormones through the rat blood-brain barrier. Primary role of albumin-bound hormone. J Clin Invest 1979; 64: 145\u201354.","journal-title":"J Clin Invest"},{"key":"BF03006535_CR105","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1073\/pnas.81.4.1140","volume":"81","author":"C Gupta","year":"1984","unstructured":"Gupta C, Katsumata M, Goldman AS et al. Glucocorticoid-induced phospholipase A2-inhibitory proteins mediate glucocorticoid teratogenicity in vitro. Proc Natn Acad Sci USA 1984; 81: 1140\u20133.","journal-title":"Proc Natn Acad Sci USA"},{"key":"BF03006535_CR106","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1161\/01.STR.4.2.148","volume":"4","author":"RF Donley","year":"1973","unstructured":"Donley RF, Sundt TM Jr. The effect of dexamethasone on the edema of focal cerebral ischemia. Stroke 1973; 4: 148\u201355.","journal-title":"Stroke"},{"key":"BF03006535_CR107","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1001\/jama.1956.02970340021007","volume":"162","author":"M Dyken","year":"1956","unstructured":"Dyken M, White PT. Evaluation of cortisone in the treatment of cerebral infarction. JAMA 1956; 162: 1531\u20134.","journal-title":"JAMA"},{"key":"BF03006535_CR108","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1126\/science.4035356","volume":"229","author":"RM Sapolsky","year":"1985","unstructured":"Sapolsky RM, Pulsinelli WA. Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications. Science 1985; 229: 1397\u2013400.","journal-title":"Science"},{"key":"BF03006535_CR109","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/257680a0","volume":"257","author":"SR Turner","year":"1975","unstructured":"Turner SR, Tainer JA, Lynn WS. Biogenesis of chemotactic molecules by the arachidonate lipoxygenase system of platelets. Nature 1975; 257: 680\u20131.","journal-title":"Nature"},{"key":"BF03006535_CR110","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1126\/science.210504","volume":"201","author":"I Fridovich","year":"1978","unstructured":"Fridovich I. The biology of oxygen radicals. Science 1978; 201: 875\u201380.","journal-title":"Science"},{"key":"BF03006535_CR111","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1084\/jem.146.6.1693","volume":"146","author":"A Granelli-Piperano","year":"1977","unstructured":"Granelli-Piperano A, Vassalli JD, Reich E. Secretion of plasminogen activator by human polymorphonuclear leukocytes. Modulation by glucocorticoids and other effectors. J Exp Med 1977; 146: 1693\u2013706.","journal-title":"J Exp Med"},{"key":"BF03006535_CR112","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.1982.tb10847.x","volume":"38","author":"LS Wolfe","year":"1982","unstructured":"Wolfe LS. Eicosanoids prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 unsaturated fatty acids. J Necurochem 1982; 38: 1\u201314.","journal-title":"J Necurochem"},{"key":"BF03006535_CR113","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1056\/NEJM197905173002006","volume":"300","author":"S Moncada","year":"1979","unstructured":"Moncada S, Vane JR. Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. N Engl J Med 1979; 300: 1142\u20137.","journal-title":"N Engl J Med"},{"key":"BF03006535_CR114","first-page":"153","volume":"492","author":"RF Maestro Del","year":"1980","unstructured":"Del Maestro RF. An approach to free radicals in medicine and biology. Acta Physiol Scand Suppl 1980; 492: 153\u201368.","journal-title":"Acta Physiol Scand Suppl"},{"key":"BF03006535_CR115","first-page":"250","volume":"523","author":"JA Salmon","year":"1978","unstructured":"Salmon JA, Smith DR, Flower RJ et al. Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacylin by porcine aorta microsomes. Biochem Biophys Acta 1978; 523: 250\u201362.","journal-title":"Biochem Biophys Acta"},{"key":"BF03006535_CR116","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0031-6997(25)06634-7","volume":"26","author":"RJ Flower","year":"1974","unstructured":"Flower RJ. Drugs which inhibit prostaglandin biosynthesis. Pharmacol Rev 1974; 26: 33\u201363.","journal-title":"Pharmacol Rev"},{"key":"BF03006535_CR117","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1161\/01.STR.10.6.629","volume":"10","author":"JM Hallenbeck","year":"1979","unstructured":"Hallenbeck JM, Furlow TW Jr. Prostaglandin I2 and indomethacin prevent impairment of post-ischemic brain reperfusion in the dog. Stroke 1979; 10: 629\u201337.","journal-title":"Stroke"},{"key":"BF03006535_CR118","first-page":"135","volume":"14","author":"BC White","year":"1985","unstructured":"White BC, Krause GS, Aust SD et al. Postischemic tissue injury by ion-mediated free radical lipid peroxidation. Ann Emerg Med 1985; 14: 135\u201340.","journal-title":"Ann Emerg Med"}],"container-title":["Canadian Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03006535.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03006535\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03006535","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T07:20:16Z","timestamp":1739085616000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03006535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,10]]},"references-count":118,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1990,10]]}},"alternative-id":["BF03006535"],"URL":"https:\/\/doi.org\/10.1007\/bf03006535","relation":{},"ISSN":["0832-610X","1496-8975"],"issn-type":[{"value":"0832-610X","type":"print"},{"value":"1496-8975","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,10]]}}}