{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T05:40:02Z","timestamp":1738820402587,"version":"3.37.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1981,11,1]],"date-time":"1981-11-01T00:00:00Z","timestamp":373420800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canad. Anaesth. Soc. J."],"published-print":{"date-parts":[[1981,11]]},"DOI":"10.1007\/bf03007148","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T16:52:37Z","timestamp":1229187157000},"page":"530-536","source":"Crossref","is-referenced-by-count":20,"title":["Regional analgesic effect of epidural morphine in volunteers"],"prefix":"10.1007","volume":"28","author":[{"given":"W. R.","family":"Thompson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. T.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hirst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. P.","family":"Varkey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. L.","family":"Knill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF03007148_CR1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0031-6997(25)07085-1","volume":"2","author":"A. Wikler","year":"1950","unstructured":"Wikler, A. Sites and mechanisms of action of morphine and related drugs in the central nervous system. Pharmacol. Rev.2: 435\u2013506 (1950).","journal-title":"Pharmacol. Rev."},{"key":"BF03007148_CR2","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1126\/science.1273597","volume":"192","author":"T.L. Yaksh","year":"1976","unstructured":"Yaksh, T.L. &Rudy, T.A. Analgesia mediated by a direct spinal action of narcotics. Science192: 1357\u20131358 (1976).","journal-title":"Science"},{"key":"BF03007148_CR3","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0006-8993(76)90296-1","volume":"112","author":"C. Lamotte","year":"1976","unstructured":"Lamotte, C., Pert, C.B. &Snyder. S.H. Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section. Brain Research112: 407\u2013412 (1976).","journal-title":"Brain Research"},{"key":"BF03007148_CR4","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0006-8993(77)90863-0","volume":"124","author":"S.F. Atweh","year":"1977","unstructured":"Atweh, S.F. &Kuhar, M.J. Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla. Brain Research124: 53\u201367 (1977).","journal-title":"Brain Research"},{"issue":"2","key":"BF03007148_CR5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0022-3565(25)29669-0","volume":"187","author":"J.M. Besson","year":"1973","unstructured":"Besson, J.M., Wyon-Maillard, M.C., Benoist, J.M., Conseiller, C. &Hamann, K.F. Effects of phenoperidine on lamina V cells in the cat dorsal horn. J. Pharmacol. Exp. Ther.187: 2, 239\u2013245 (1973).","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1","key":"BF03007148_CR6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/00000542-197407000-00008","volume":"41","author":"L.M. Kitahata","year":"1974","unstructured":"Kitahata, L.M., Kosaka, Y., Taub, A., Bonikos, K. &Hoffert, M. Lamina \u2014 specific suppression of dorsal-horn unit activity by morphine sulfate. Anesthesiology41: 1, 39\u201348 (1974).","journal-title":"Anesthesiology"},{"key":"BF03007148_CR7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1476-5381.1977.tb09740.x","volume":"61","author":"A.W. Duggan","year":"1977","unstructured":"Duggan, A.W., Hall, J.G. &Headley, P.M. Suppression of transmission of nociceptive impulses by morphine: Selective effects of morphine administered in the region of the substantia gelatinosa. Br. J. Pharmacol.61: 65\u201376 (1977).","journal-title":"Br. J. Pharmacol."},{"key":"BF03007148_CR8","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0304-3959(77)90145-2","volume":"4","author":"T.L. Yaksh","year":"1978","unstructured":"Yaksh, T.L. &Rudy, T.A. Narcotic Analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques. Pain4: 299\u2013359 (1978).","journal-title":"Pain"},{"key":"BF03007148_CR9","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/00000542-197902000-00013","volume":"50","author":"J.K. Wang","year":"1979","unstructured":"Wang, J.K., Nauss, L.A. &Thomas. J.E. Pain relief by intrathecally applied morphine in man. Anesthesiology50: 149\u2013151 (1979).","journal-title":"Anesthesiology"},{"key":"BF03007148_CR10","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/BF03007147","volume":"28","author":"I. Anderson","year":"1981","unstructured":"Anderson, I., Thompson, W.R., Varkey, G.P. &Knill, R.L. Lumbar epidural morphine is an effective analgesic following cholecystectomy. Can. Anaesth. Soc. J.28:101, (1981).","journal-title":"Can. Anaesth. Soc. J."},{"key":"BF03007148_CR11","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0140-6736(79)91817-8","volume":"1","author":"M.J. Cousins","year":"1979","unstructured":"Cousins, M.J., Mather, L.E., Glynn, C.J., Wilson, P.R. &Graham, J.R. Selective spinal analgesia. Lancet1: 1141\u20131142 (1979).","journal-title":"Lancet"},{"key":"BF03007148_CR12","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/bja\/52.3.247","volume":"52","author":"F. Magora","year":"1980","unstructured":"Magora, F., Olshwang, D., Eimerl. D., Shorr, J., Katzenelson, R., Cotev, S. &Davidson, J.T. Observations on extradural morphine analgesia in various pain conditions. Br. J. Anaesth.52: 247\u2013252 (1980).","journal-title":"Br. J. Anaesth."},{"key":"BF03007148_CR13","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1093\/bja\/52.9.939","volume":"52","author":"T.A. Torda","year":"1980","unstructured":"Torda, T.A., Pybus, D.A., Liberman. H., Clark, M. &Crawford, M. Experimental comparison of extradural and I.M. morphine. Br. J. Anaesth.52: 939\u2013942 (1980).","journal-title":"Br. J. Anaesth."},{"key":"BF03007148_CR14","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0304-3959(80)90003-2","volume":"9","author":"P.R. Bromage","year":"1980","unstructured":"Bromage, P.R., Camporesi, E. &Leslie, J. Epidural narcotics in volunteers: Sensitivity to pain and to carbon dioxide. Pain9: 145\u2013160 (1980).","journal-title":"Pain"},{"issue":"1","key":"BF03007148_CR15","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/00000542-198101000-00015","volume":"54","author":"H. Asari","year":"1981","unstructured":"Asari H., Inoue, K., Shibata, T. &Soga, T. Segmental effect of morphine injected into the epidural space in man. Anesthesiology54: 1, 75\u201377 (1981).","journal-title":"Anesthesiology"},{"key":"BF03007148_CR16","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1177\/0310057X7900700411","volume":"7","author":"T.A. Torda","year":"1979","unstructured":"Torda, T.A. Epidural analgesia with morphine. A preliminary communication. Anaesth. Intens. Care7: 367\u2013370 (1979).","journal-title":"Anaesth. Intens. Care"},{"key":"BF03007148_CR17","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1213\/00000539-198007000-00003","volume":"59","author":"P.R. Bromage","year":"1980","unstructured":"Bromage, P.R., Camporesi, E. &Chestnut, D. Epidural narcotics for postoperative analgesia. Anesth. Analg.59: 473\u2013480 (1980).","journal-title":"Anesth. Analg."},{"key":"BF03007148_CR18","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/BF03007149","volume":"28","author":"R.L. Knill","year":"1981","unstructured":"Knill, R.L., Clement, J.L. &Thompson, W.R. Epidural morphine causes delayed and prolonged ventilatory depression. Can. Anaesth. Soc. J.28: 537\u2013543 (1981).","journal-title":"Can. Anaesth. Soc. J."},{"key":"BF03007148_CR19","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0022-3565(25)28095-8","volume":"163","author":"G.M. Smith","year":"1968","unstructured":"Smith, G.M., Lowenstein, E., Hubbard, J.H. &Beecher, H.K. Experimental pain produced by the submaximum effort tourniquet technique: further evidence of validity. J. Pharmacol Exp. Ther.163: 468\u2013474 (1968).","journal-title":"J. Pharmacol Exp. Ther."},{"key":"BF03007148_CR20","volume-title":"Biom\u00e9dical computer program \u2014 P-series","author":"W.J. Dixon","year":"1979","unstructured":"Dixon, W.J. &Brown, M.B. Biom\u00e9dical computer program \u2014 P-series, Berkeley: University of California Press (1979)."},{"key":"BF03007148_CR21","volume-title":"Measurement of subjective responses","author":"H.K. Beecher","year":"1959","unstructured":"Beecher, H.K. Measurement of subjective responses, Chapter 2, New York: Oxford University Press (1959)."},{"key":"BF03007148_CR22","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1111\/j.1365-2044.1979.tb06326.x","volume":"34","author":"J.W.L. Parry","year":"1979","unstructured":"Parry, J.W.L. The evaluation of analgesic drugs. Anaesthesia34: 468\u2013475 (1979).","journal-title":"Anaesthesia"},{"key":"BF03007148_CR23","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0304-3959(79)90055-1","volume":"6","author":"P.A. Moore","year":"1979","unstructured":"Moore, P.A., Duncan, G.H., Scott, D.S., Gregg, J.M. &Ghia, J.N. The submaximal effort tourniquet test: Its use in evaluating experimental and chronic pain. Pain6: 375\u2013382 (1979).","journal-title":"Pain"},{"key":"BF03007148_CR24","volume-title":"Measurement of subjective responses","author":"H.K. Beecher","year":"1959","unstructured":"Beecher, H.K. Measurement of subjective responses. Chapter 6, New York: Oxford University Press (1959)."},{"key":"BF03007148_CR25","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/cpt1975176629","volume":"17","author":"B.A. Berkowitz","year":"1975","unstructured":"Berkowitz, B.A., Ngai, S.H., Yang, J.C., Hempstead, J. &Spector, S. The disposition of morphine in surgical patients. Clin. Pharmacol. Ther.17: 629\u2013635 (1975).","journal-title":"Clin. Pharmacol. Ther."},{"key":"BF03007148_CR26","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/00000542-198010000-00010","volume":"53","author":"M.S. Chayen","year":"1980","unstructured":"Chayen, M.S., Rudick, V. &Borvine, A. Pain control with epidural injection of morphine. Anesthesiology53: 338\u2013339 (1980).","journal-title":"Anesthesiology"},{"key":"BF03007148_CR27","first-page":"79","volume":"6","author":"A. Herz","year":"1971","unstructured":"Herz, A. &Teschemacher, H.J. Activities and antinociceplive action of morphine-like analgesics. Advances in Drug Research6: 79\u2013119 (1971).","journal-title":"Advances in Drug Research"},{"key":"BF03007148_CR28","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0022-3565(25)30972-9","volume":"202","author":"T.L. Yaksh","year":"1977","unstructured":"Yaksh, T.L. &Rudy, T.A. Studies on the direct spinal action of narcotics in the production of analgesia in the rat. J. Pharmacol. Exp. Ther.202: 411\u2013428 (1977).","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"BF03007148_CR29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0140-6736(80)90089-6","volume":"2","author":"S. Reiz","year":"1980","unstructured":"Reiz, S. &Westberg, M. Side-effects of epidural morphine. Lancet2: 203\u2013204 (1980).","journal-title":"Lancet"}],"container-title":["Canadian Anaesthetists\u2019 Society Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03007148.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03007148\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03007148","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T05:06:57Z","timestamp":1738818417000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03007148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,11]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1981,11]]}},"alternative-id":["BF03007148"],"URL":"https:\/\/doi.org\/10.1007\/bf03007148","relation":{},"ISSN":["0008-2856","1496-8975"],"issn-type":[{"type":"print","value":"0008-2856"},{"type":"electronic","value":"1496-8975"}],"subject":[],"published":{"date-parts":[[1981,11]]}}}