{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:08:39Z","timestamp":1792084119662,"version":"4.4.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["neurotox res"],"published-print":{"date-parts":[[2003,1]]},"DOI":"10.1007\/bf03033153","type":"journal-article","created":{"date-parts":[[2009,7,20]],"date-time":"2009-07-20T17:12:16Z","timestamp":1248109936000},"page":"329-338","source":"Crossref","is-referenced-by-count":28,"title":["Ontogenetic quinpirole treatments fail to prime for D2 agonist-enhancement of locomotor activity in 6-hydroxydopamine-lesioned rats"],"prefix":"10.1007","volume":"5","author":[{"given":"Ryszard","family":"Brus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard M.","family":"Kostrzewa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preemyslaw","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken W.","family":"Perry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Kostrzewa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF03033153_CR1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0022-3565(25)21630-5","volume":"231","author":"GR Breese","year":"1984","unstructured":"Breese GR, AA Baumeister, TJ McCown, SG Emerick, GD Frye, K Crotty and RA Mueller (1984) Behavioural differences between neonatal and adult 6-hydroxydopamine-treated rats to dopamine agonists: relevance to neurological symptoms in clinical syndromes with reduced brain dopamine.J Pharm. Exp. Ther. 231, 343\u2013354.","journal-title":"J Pharm. Exp. Ther."},{"key":"BF03033153_CR2","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0022-3565(25)23963-5","volume":"235","author":"GR Breese","year":"1985","unstructured":"Breese GR, AA Baumeister, TC Napier, GD Frye and RA Mueller (1985a) Evidence that D-1 dopamine receptors contribute to the supersensitive behavioral responses induced by L-dihydroxyphenylalanine in rat treated neonatally with 6-hydroxydopamine.J. Pharm. Exp. Ther. 235, 287\u2013295.","journal-title":"J. Pharm. Exp. Ther."},{"key":"BF03033153_CR3","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0022-3565(25)23467-X","volume":"234","author":"GR Breese","year":"1985","unstructured":"Breese GR, TC Napier and RA Mueller (1985b) Dopamine agonist-induced locomotor activity in rats treated with 6-hydroxydopamine at differing ages: Functional supersensitivity of D-1 dopamine receptors in neonatally-lesioned rats.J. Pharm. Exp. Ther. 234, 447\u2013455.","journal-title":"J. Pharm. Exp. Ther."},{"key":"BF03033153_CR4","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0022-3565(25)22697-0","volume":"240","author":"GR Breese","year":"1987","unstructured":"Breese GR, GE Duncan, TC Napier, SC Bondy, LC Iorio and RA Mueller (1987) 6-Hydroxydopamine treatment enhance behavioral responses to intracerebral microinjection of D(1)- and D(2)-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.J. Pharm. Exp. Ther. 240, 167\u2013176.","journal-title":"J. Pharm. Exp. Ther."},{"key":"BF03033153_CR5","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1111\/j.1476-5381.1991.tb12546.x","volume":"104","author":"CA Briggs","year":"1991","unstructured":"Briggs CA, NJ Pollock, DE Frail, CL Paxson, RF Rakowski, CH Kang and JW Kebabian (1991) Activation of the 5-HT1C receptor expressed inXenopus oocytes by the benzazepines SCH 23390 and SKF 38393.Br. J. Pharmacol. 104, 1038\u20131044.","journal-title":"Br. J. Pharmacol."},{"key":"BF03033153_CR6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.55782\/ane-1996-1098","volume":"56","author":"R Brus","year":"1996","unstructured":"Brus R, R Szkilnik and RM Kostrzewa (1996) Nitric oxide (NO) and central dopamine (DA) D3 receptor reactivity in rats.Acta Neurobiol. Exp. 56, 15\u201319.","journal-title":"Acta Neurobiol. Exp."},{"key":"BF03033153_CR7","first-page":"25","volume":"10","author":"R Brus","year":"1998","unstructured":"Brus R, R Szkilnik, P Nowak, A Kasperska, J O\u015bwi\u0119cimska, RM Kostrzewa and J Shani (1998) Locomotor sensitization of dopamine receptors by their agonists quinpirole and SKF-38393, during maturation and aging in rats.Pharmacol. Rev. Commun. 10, 25\u201330.","journal-title":"Pharmacol. Rev. Commun."},{"key":"BF03033153_CR8","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1523\/JNEUROSCI.09-01-00125.1989","volume":"9","author":"H Criswell","year":"1989","unstructured":"Criswell H, RA Mueller and GR Breese (1989) Priming of D1-dopamine receptor responses: long-lasting behavioral supersensitivity to a D1-dopamine agonist following repeated administration to neonatal 6-OHDA.-lesioned rats.J. Neurosci. 9, 125\u2013133.","journal-title":"J. Neurosci."},{"key":"BF03033153_CR9","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0014-2999(89)90837-6","volume":"161","author":"D Eilam","year":"1993","unstructured":"Eilam D and H Szechtman (1993) Biphasic effect of the D2 agonist quinpirole on locomotion and movements.Eur. J. Pharmacol. 161, 151\u2013157.","journal-title":"Eur. J. Pharmacol."},{"key":"BF03033153_CR10","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00008877-199308000-00013","volume":"4","author":"H Einat","year":"1993","unstructured":"Einat H and H Szechtman (1993) Environmental modulation of both locomotor response and locomotor sensitization to the dopamine agonist quinpirole.Behav. Pharmacol. 4, 393\u2013403","journal-title":"Behav. Pharmacol."},{"key":"BF03033153_CR11","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/BF02805980","volume":"127","author":"H Einat","year":"1996","unstructured":"Einat H, D Einat, M Allan, H Talangbayan, T Tsafnat and H Szechtman (1996) Associational and nonassociational mechanisms in locomotor sensitization to the dopamine agonist quinpirole.Psychopharmacology (Berl).127, 95\u2013101.","journal-title":"Psychopharmacology (Berl)"},{"key":"BF03033153_CR12","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0022-3565(25)11111-7","volume":"261","author":"L Gong","year":"1992","unstructured":"Gong L, RM Kostrzewa, RW Fuller and KW Perry (1992) Supersensitization of the oral response to SKF 38393 in neonatal 6-OHDA-lesioned rats is mediated through a serotonin system.J. Pharmacol. Exp. Ther. 261, 1000\u20131007.","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"BF03033153_CR13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0165-3806(93)90122-Q","volume":"76","author":"L Gong","year":"1993","unstructured":"Gong L, RM Kostrzewa, R Brus, RW Fuller and KW Perry (1993) Ontogenetic SKF 38393 treatments sensitize dopamine D1 receptors in neonatal 6-OHDA-lesioned rats.Dev. Brain Res. 76, 59\u201365.","journal-title":"Dev. Brain Res."},{"key":"BF03033153_CR14","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1046\/j.1471-4159.1994.63041282.x","volume":"63","author":"L Gong","year":"1994","unstructured":"Gong L, RM Kostrzewa and C Li (1994) Neonatal 6-OHDA and adult SKF 38393 treatments alter dopamine D1 receptor mRNA levels: absence of other neurochemical associations with the enhanced behavioral responses of lesioned rats.J. Neurochem. 63, 1282\u20131290.","journal-title":"J. Neurochem."},{"key":"BF03033153_CR15","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0014-2999(94)90803-6","volume":"271","author":"NY Huang","year":"1994","unstructured":"Huang NY and RM Kostrzewa (1994) Persistent oral dyskinesias in haloperidol-withdrawn neonatal 6-hydroxydopamine-lesioned rats.Eur. J. Pharmacol. 271, 433\u2013437.","journal-title":"Eur. J. Pharmacol."},{"key":"BF03033153_CR16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0149-7634(94)00019-W","volume":"19","author":"RM Kostrzewa","year":"1995","unstructured":"Kostrzewa RM (1995) Dopamine receptor supersensitivity.Neurosci. Biobehav. Rev. 19, 1\u201317.","journal-title":"Neurosci. Biobehav. Rev."},{"key":"BF03033153_CR17","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/0091-3057(91)90219-R","volume":"39","author":"RM Kostrzewa","year":"1991","unstructured":"Kostrzewa RM and R Brus (1991) Ontogenic homologous super-sensitization of quinpirole-induced yawning in rats.Pharmacol. Biochem. Behav. 39, 517\u2013519.","journal-title":"Pharmacol. Biochem. Behav."},{"key":"BF03033153_CR18","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/0091-3057(91)90146-S","volume":"39","author":"RM Kostrzewa","year":"1991","unstructured":"Kostrzewa RM and L Gong (1991) Supersensitized D1 receptors mediate enhanced oral activity after neonatal 6-OHDA.Pharmacol. Biochem. Behav. 39, 677\u2013682.","journal-title":"Pharmacol. Biochem. Behav."},{"key":"BF03033153_CR19","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/0014-2999(90)94542-6","volume":"183","author":"RM Kostrzewa","year":"1990","unstructured":"Kostrzewa RM, A Hamdi and FP Kostrzewa (1990) Production of prolonged supersensitization of dopamine D2 receptors.Eur. J. Pharmacol. 183, 1411\u20131412.","journal-title":"Eur. J. Pharmacol."},{"key":"BF03033153_CR20","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0014-2999(91)90164-L","volume":"209","author":"RM Kostrzewa","year":"1991","unstructured":"Kostrzewa RM, R Brus and J Kalbfleisch (1991) Ontogenetic homologous sensitization to the antinociceptive action of quinpirole in rats.Eur. J. Pharmacol. 209, 157\u2013161.","journal-title":"Eur. J. Pharmacol."},{"key":"BF03033153_CR21","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0165-3806(93)90126-U","volume":"76","author":"RM Kostrzewa","year":"1993","unstructured":"Kostrzewa RM, R Brus, KW Perry and RW Fuller (1993a) Age-dependence of a 6-hydroxydopamine lesion on SKF 38393- andm-chlorophenylpiperazine-induced oral activity responses of rats.Dev. Brain Res. 76, 87\u201393.","journal-title":"Dev. Brain Res."},{"key":"BF03033153_CR22","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0091-3057(93)90496-G","volume":"44","author":"RM Kostrzewa","year":"1993","unstructured":"Kostrzewa RM, R Brus, M Rykaczewska and A Plech (1993b) Low dose quinpirole ontogenically sensitizes to quinpirole-induced yawning in rats.Pharmacol. Biochem. Behav. 44, 487\u2013489.","journal-title":"Pharmacol. Biochem. Behav."},{"key":"BF03033153_CR23","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0014-2999(93)90992-Q","volume":"239","author":"RM Kostrzewa","year":"1993","unstructured":"Kostrzewa RM, J Guo and FP Kostrzewa (1993c) Ontogenetic quinpirole treatments induce vertical jumping activity in rats.Eur. J. Pharmacol. 239, 183\u2013187.","journal-title":"Eur. J. Pharmacol."},{"key":"BF03033153_CR24","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1046\/j.1471-4159.1998.70030889.x","volume":"70","author":"RM Kostrzewa","year":"1998","unstructured":"Kostrzewa RM, TA Reader and L Descarries (1998) Serotonin neural adaptations to ontogenetic loss of dopamine neurons in rat brain.J. Neurochem. 70, 889\u2013898.","journal-title":"J. Neurochem."},{"key":"BF03033153_CR25","first-page":"319","volume":"53","author":"P Nowak","year":"2001","unstructured":"Nowak P, R Brus and RM Kostrzewa (2001) Amphetamine-induced enhancement of neostriatal in vivo microdialysate dopamine content in rats, quinpirole-primed as neonates.Pol. J. Pharmacol. 53, 319\u2013329.","journal-title":"Pol. J. Pharmacol."},{"key":"BF03033153_CR26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0091-3057(00)00296-3","volume":"67","author":"J O\u015bwi\u0119cimska","year":"2000","unstructured":"O\u015bwi\u0119cimska J, R Brus, R Szkilnik, P Nowak and RM Kostrzewa (2000) 7-OH-DPAT, unlike quinpirole, does not prime a yawning response in rats.Pharmacol. Biochem. Behav. 67, 11\u201315.","journal-title":"Pharmacol. Biochem. Behav."},{"key":"BF03033153_CR27","first-page":"203","volume":"11","author":"J O\u015bwi\u0119cimska","year":"2001","unstructured":"O\u015bwi\u0119cimska J, R Brus, R Szkilnik, A Sokola, RM Kostrzewa and J Shani (2001) Sexual differentiation in behavioral patterns of rats, pretreated with two central dopamine agonists: quinpirole and 7-OH-DPAT.Pharmacol. Rev. Commun. 11, 203\u2013213.","journal-title":"Pharmacol. Rev. Commun."},{"key":"BF03033153_CR28","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0014-2999(78)90148-6","volume":"50","author":"PE Setler","year":"1978","unstructured":"Setler PE, HM Sarau, CL Zirkle and HL Saunders (1978) The central effects of a novel dopamine agonist.Eur. J. Pharmacol. 50, 419\u2013430.","journal-title":"Eur. J. Pharmacol."},{"key":"BF03033153_CR29","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/0091-3057(94)90201-1","volume":"48","author":"H Szechtman","year":"1994","unstructured":"Szechtman H, H Dai, H Einat and R Sullivan (1994) Effects of dose and inter-dose interval on locomotion sensitization to the dopamine agonist quinpirole.Pharmacol. Biochem. Behav. 48, 921\u2013928.","journal-title":"Pharmacol. Biochem. Behav."},{"key":"BF03033153_CR30","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s002130050442","volume":"134","author":"KK Szumlinski","year":"1997","unstructured":"Szumlinski KK, M Allan, H Talangbayan, A Tracey and H Szechtman (1997) Locomotor sensitization to quinpirole: environment-modulated increase in efficacy and context-dependent increase in potency.Psychopharmacology (Berl.) 134, 193\u2013200.","journal-title":"Psychopharmacology (Berl.)"},{"key":"BF03033153_CR31","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s002130051078","volume":"145","author":"Y Tizabi","year":"1999","unstructured":"Tizabi Y, RL Copeland Jr, R Brus and RM Kostrzewa (1999) Nicotine blocks quinpirole-induced behavior in rats: psychiatric implications.Psychopharmacology (Berl.) 145, 433\u2013441.","journal-title":"Psychopharmacology (Berl.)"},{"key":"BF03033153_CR32","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/S0022-3565(25)13248-5","volume":"253","author":"AS Undie","year":"1990","unstructured":"Undie AS and E Friedman (1990) Stimulation of a dopamine D1 receptor enhances inositol phosphates formation in rat brain.J. Pharmacol. Exp. Ther. 253, 987\u2013992.","journal-title":"J. Pharmacol. Exp. Ther."}],"container-title":["Neurotoxicity Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03033153.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03033153\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03033153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T05:28:22Z","timestamp":1739251702000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03033153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["BF03033153"],"URL":"https:\/\/doi.org\/10.1007\/bf03033153","relation":{},"ISSN":["1029-8428","1476-3524"],"issn-type":[{"value":"1029-8428","type":"print"},{"value":"1476-3524","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1]]}}}