{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T19:09:11Z","timestamp":1775329751761,"version":"3.50.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1997,8,1]],"date-time":"1997-08-01T00:00:00Z","timestamp":870393600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Herz"],"published-print":{"date-parts":[[1997,8]]},"DOI":"10.1007\/bf03044576","type":"journal-article","created":{"date-parts":[[2009,6,6]],"date-time":"2009-06-06T02:13:52Z","timestamp":1244254432000},"page":"183-189","source":"Crossref","is-referenced-by-count":4,"title":["Transmyokardiale Laserrevaskularisation \u2014 Ein innovatives pathophysiologisches Konzept","Transmyocardial laser revascularization: a novel pathophysiological concept"],"prefix":"10.1007","volume":"22","author":[{"given":"C. G.","family":"Brilla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Rybinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Gehrke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Rupp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF03044576_CR1","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1073\/pnas.92.23.10457","volume":"92","author":"LP Aiello","year":"1995","unstructured":"Aiello LP, Pierce EA, Foley ED et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci USA 1995;92:1057\u201361.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF03044576_CR2","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1001\/archopht.1995.01100120068012","volume":"113","author":"LP Aiello","year":"1995","unstructured":"Aiello LP, Northrup JM, Keyt BA, Takagi H, Iwamoto MA. Hypoxic regulation of vascular endothelial growth factor in retinal cells. Arch Ophthalmol 1995;113:1538\u201344.","journal-title":"Arch Ophthalmol"},{"key":"BF03044576_CR3","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1096\/fasebj.11.5.9141503","volume":"11","author":"L Beck","year":"1997","unstructured":"Beck L, dAmore PA. Vascular development: cellular and molecular regulation. FASEB J 1997;11:365\u201373.","journal-title":"FASEB J"},{"key":"BF03044576_CR4","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF00666041","volume":"36","author":"P Bevilacqua","year":"1995","unstructured":"Bevilacqua P, Barbareschi M, Verderio P et al. Prognostic value of intratumoral microvessel density, a measure of tumor angiogenesis, in node-negative breast carcinoma \u2014 results of a multiparametric study. Breast Cancer Res Treat 1995;36:205\u201317.","journal-title":"Breast Cancer Res Treat"},{"key":"BF03044576_CR5","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/0092-8674(94)90007-8","volume":"79","author":"PC Brooks","year":"1994","unstructured":"Brooks PC, Montgomery AM, Rosenfeld M et al. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994;79:1157\u201364.","journal-title":"Cell"},{"key":"BF03044576_CR6","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0092-8674(00)81235-0","volume":"85","author":"PC Brooks","year":"1996","unstructured":"Brooks PC, Stromblad S, Sanders LC et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 1996;85:683\u201393.","journal-title":"Cell"},{"key":"BF03044576_CR7","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1172\/JCI118227","volume":"96","author":"PC Brooks","year":"1995","unstructured":"Brooks PC, Stromblad S, Klemke R, Visscher D, Sarkar FH, Cheresh DA. Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest 1995;96:1815\u201322.","journal-title":"J Clin Invest"},{"key":"BF03044576_CR8","first-page":"1407","volume":"148","author":"RA Clark","year":"1996","unstructured":"Clark RA, Tonnesen MG, Gailit J, Cheresh DA. Transient functional expression of alpha Vbeta 3 on vascular cells during wound repair. Am J Pathol 1996;148:1407\u201321.","journal-title":"Am J Pathol"},{"key":"BF03044576_CR9","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S0022-5223(96)70339-2","volume":"111","author":"DA Cooley","year":"1996","unstructured":"Cooley DA, Frazier OH, Kadipasaoglu KA et al. Transmyocardial laser revascularization: clinical experience with twelvemonth follow-up J Thorac Cardiovasc Surg 1996;111:791\u20137.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BF03044576_CR10","first-page":"220","volume":"21","author":"DA Cooley","year":"1994","unstructured":"Cooley DA, Frazier OH, Kadipasaoglu KA et al. Transmyocardial laser revascularization. Anatomic evidence of long-term channel patency. Tex Heart Inst J 1994;21:220\u20134.","journal-title":"Tex Heart Inst J"},{"key":"BF03044576_CR11","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1006\/excr.1995.1015","volume":"216","author":"GE Davis","year":"1995","unstructured":"Davis GE, Camarillo CW. Regulation of endothelial cell morphogenesis by integrins, mechanical forces, and matrix guidance pathways. Exp Cell Res 1995;216:113\u201323.","journal-title":"Exp Cell Res"},{"key":"BF03044576_CR12","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/S0092-8674(00)81812-7","volume":"87","author":"S Davis","year":"1996","unstructured":"Davis S, Aldrich TH, Jones PF et al. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 1996;87:1161\u20139.","journal-title":"Cell"},{"key":"BF03044576_CR13","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/1523-1747.ep12286453","volume":"108","author":"M Detmar","year":"1997","unstructured":"Detmar M, Brown LF, Berse B et al. Hypoxia regulates the expression of vascular permeability factor\/vascular endothelial growth factor (VPF\/VEGF) and its receptors in human skin. J Invest Dermatol 1997;108:263\u20138.","journal-title":"J Invest Dermatol"},{"key":"BF03044576_CR14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00666035","volume":"36","author":"N Ferrara","year":"1995","unstructured":"Ferrara N. The role of vascular endothelial growth factor in pathological angiogenesis. Breast Cancer Res Treat 1995;36:127\u201337.","journal-title":"Breast Cancer Res Treat"},{"key":"BF03044576_CR15","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1126\/science.270.5241.1500","volume":"270","author":"M Friedlander","year":"1995","unstructured":"Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA. Definition of two angiogenic pathways by distinct alpha v integrins. Science 1995;270:1500\u20132.","journal-title":"Science"},{"key":"BF03044576_CR16","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1159\/000128688","volume":"19","author":"T Goda","year":"1987","unstructured":"Goda T, Wierzbicki Z, Gaston A, Leandri J, Vouron J, Loisance D. Myocardial revascularization by CO2 laser. Eur Surg Res 1987;19:113\u20137.","journal-title":"Eur Surg Res"},{"key":"BF03044576_CR17","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF01803788","volume":"38","author":"AL Harris","year":"1996","unstructured":"Harris AL, Zhang H, Moghaddam A et al. Breast cancer angiogenesis \u2014 new approaches to therapy via antiangiogenesis, hypoxic activated drugs, and vascular targeting. Breast Cancer Res Treat 1996;38:97\u2013108.","journal-title":"Breast Cancer Res Treat"},{"key":"BF03044576_CR18","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1006\/bbrc.1994.2831","volume":"205","author":"M Iizuka","year":"1994","unstructured":"Iizuka M, Yamauchi M, Ando K et al. Quantitative RT-PCR assay detecting the transcriptional induction of vascular endothelial growth factor under hypoxia. Biochem Biophys Res Commun 1994;205:1474\u201380.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF03044576_CR19","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1172\/JCI117523","volume":"94","author":"RK Khouri","year":"1994","unstructured":"Khouri RK, Hong SP, Deune EG et al. De novo generation of permanent neovascularized soft tissue appendages by plateletderived growth factor. J Clin Invest 1994;94:1757\u201363.","journal-title":"J Clin Invest"},{"key":"BF03044576_CR20","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1083\/jcb.113.6.1439","volume":"113","author":"S Kojima","year":"1991","unstructured":"Kojima S, Harpel PC, Rifkin DB. Lipoprotein (a) inhibits the generation of transforming growth factor beta: an endogenous inhibitor of smooth muscle cell migration. J Cell Biol 1991;113:1439\u201345.","journal-title":"J Cell Biol"},{"key":"BF03044576_CR21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/lsm.1900110109","volume":"11","author":"R Landreneau","year":"1991","unstructured":"Landreneau R, Nawarawong W, Laughlin H et al. Direct CO2 laser \u201crevascularization\u201d of the myocardium. Lasers Surg Med 1991;11:35\u201342.","journal-title":"Lasers Surg Med"},{"key":"BF03044576_CR22","first-page":"I","volume":"94","author":"B Maisch","year":"1996","unstructured":"Maisch B, Funck R, Herzum M et al. Does transmyocardial laser revascularization influence prognosis in endstage coronary artery disease? Circulation 1996;94:I-1716 (abstract).","journal-title":"Circulation"},{"issue":"Suppl 6","key":"BF03044576_CR23","first-page":"269","volume":"85","author":"B Maisch","year":"1996","unstructured":"Maisch B, Funck R, Sch\u00f6nian U, Moosdorf R. Indikationen zur transmyokardialen Lasertherapie. Z Kardiol 1996;85:Suppl 6:269\u201379.","journal-title":"Z Kardiol"},{"key":"BF03044576_CR24","first-page":"1615","volume":"56","author":"B Millauer","year":"1996","unstructured":"Millauer B, Longhi MP, Plate KH et al. Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo. Cancer Res. 1996;56:1615\u201320.","journal-title":"Cancer Res."},{"key":"BF03044576_CR25","first-page":"73","volume":"9","author":"M Mirhoseini","year":"1990","unstructured":"Mirhoseini M, Shelgikar S, Cayton M. Clinical and histologic evaluation of laser myocardial revascularization J Clin Laser Med Surg 1990;9:73\u20138.","journal-title":"J Clin Laser Med Surg"},{"key":"BF03044576_CR26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1089\/clm.1993.11.15","volume":"11","author":"M Mirhoseini","year":"1993","unstructured":"Mirhoseini M, Shelgikar S, Cayton MM. Transmyocardial laser revascularization: a review. J Clin Laser Med Surg 1993:11; 15\u20139.","journal-title":"J Clin Laser Med Surg"},{"key":"BF03044576_CR27","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s003920050045","volume":"86","author":"R Moosdorf","year":"1997","unstructured":"Moosdorf R, Schoebel F-C, Hort W: Transmyokardiale Laserrevaskularisation \u2014 Morphologische, pathophysiologische und historische Grundlagen der indirekten. Revaskularisation des Herzmuskels. Z Kardiol 1997;86:149\u201364.","journal-title":"Z Kardiol"},{"key":"BF03044576_CR28","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/375577a0","volume":"375","author":"D Mukhopadhyay","year":"1995","unstructured":"Mukhopadhyay D, Tsiokas L, Zhou XM et al. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 1995;375:577\u201381.","journal-title":"Nature"},{"key":"BF03044576_CR29","doi-asserted-by":"crossref","first-page":"31189","DOI":"10.1074\/jbc.270.52.31189","volume":"270","author":"A Namiki","year":"1995","unstructured":"Namiki A, Brogi E, Kearney M et al. Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells. J Biol Chem 1995;270:31189\u201395.","journal-title":"J Biol Chem"},{"key":"BF03044576_CR30","first-page":"638","volume":"72","author":"J Pe\u2019er","year":"1995","unstructured":"Pe\u2019er J, Shweiki D, Itin A et al. Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases. Lab Invest 1995;72:638\u201345.","journal-title":"Lab Invest"},{"key":"BF03044576_CR31","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/0006-291X(91)91276-I","volume":"181","author":"MS Repper","year":"1991","unstructured":"Repper MS, Ferrara N, Orci L, Montesano R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 1991;181:902\u20136.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF03044576_CR32","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1002\/(SICI)1097-0142(19960415)77:8<1419::AID-CNCR1>3.0.CO;2-7","volume":"77","author":"DF Roychowdhury","year":"1996","unstructured":"Roychowdhury DF, Tseng A Jr, Fu KK et al. New prognostic factors in nasopharyngeal carcinoma. Tumor angiogenesis and C-erbB2 expression. Cancer 1996;77:1419\u201326.","journal-title":"Cancer"},{"key":"BF03044576_CR33","first-page":"I","volume":"94","author":"L Rybinski","year":"1996","unstructured":"Rybinski L, Moosdorf R, Brittinger A, Gehrke D, Brilla CG. Transmyocardial laser revascularization: lack of channel patency in an experimental pig model. Circulation 1996;94:I-476 (abstract).","journal-title":"Circulation"},{"key":"BF03044576_CR34","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/376070a0","volume":"376","author":"TN Sato","year":"1995","unstructured":"Sato TN, Tozawa Y, Deutsch U et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995;376:70\u20134.","journal-title":"Nature"},{"key":"BF03044576_CR35","doi-asserted-by":"crossref","first-page":"9355","DOI":"10.1073\/pnas.90.20.9355","volume":"90","author":"TN Sato","year":"1993","unstructured":"Sato TN, Qin Y, Kozak CA, Audus KL. Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system [published erratum appears in Proc Natl Acad Sci USA 1993;90:12056]. Proc Natl Acad Sci USA 1993;90:9355\u20138.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF03044576_CR36","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/376062a0","volume":"376","author":"F Shalaby","year":"1995","unstructured":"Shalaby F, Rossant J, Yamaguchi TP et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 1995;376:62\u20136.","journal-title":"Nature"},{"key":"BF03044576_CR37","first-page":"3540","volume":"56","author":"LM Strawn","year":"1996","unstructured":"Strawn LM, McMahon G, App H et al. Flk-1 as a target for tumor growth inhibition. Cancer Res 1996;56:3540\u20135.","journal-title":"Cancer Res"},{"key":"BF03044576_CR38","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/S0092-8674(00)81813-9","volume":"87","author":"C Suri","year":"1996","unstructured":"Suri C, Jones PF, Patan S et al. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 1996;87:1171\u201380.","journal-title":"Cell"},{"key":"BF03044576_CR39","first-page":"1311","volume":"37","author":"H Takagi","year":"1996","unstructured":"Takagi H, King GL, Ferrara N, Aiello LP. Hypoxia regulates vascular endothelial growth factor receptor KDR\/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells. Invest Ophthalmol Vis Sci 1996;37:1311\u201321.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"BF03044576_CR40","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/hed.2880170212","volume":"17","author":"C Waes van","year":"1995","unstructured":"van Waes C. Cell adhesion and regulatory molecules involved in tumor formation. hemostasis, and wound healing. Head Neck 1995;17:140\u20137.","journal-title":"Head Neck"},{"key":"BF03044576_CR41","first-page":"6222","volume":"55","author":"NS Waleh","year":"1995","unstructured":"Waleh NS, Brody MD, Knapp MA et al. Mapping of the vascular endothelial growth factor-producing hypoxic cells in multicellular tumor spheroids using a hypoxia-specific marker. Cancer Res 1995;55:6222\u20136.","journal-title":"Cancer Res"},{"key":"BF03044576_CR42","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/BF00666038","volume":"36","author":"N Weidner","year":"1995","unstructured":"Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat 1995;36:169\u201380.","journal-title":"Breast Cancer Res Treat"},{"issue":"Suppl 5","key":"BF03044576_CR43","first-page":"13","volume":"13","author":"G Weng","year":"1993","unstructured":"Weng G, Williamson WA, Aretz HT et al. The effect of holmium: YAG laser mediated transmyocardial channels on left ventricular contractility in an acute ischemic model. Lasers Surg Med 1993;13:Suppl 5:13. abstract.","journal-title":"Lasers Surg Med"},{"key":"BF03044576_CR44","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/0735-1097(93)90848-U","volume":"22","author":"P Whittaker","year":"1993","unstructured":"Whittaker P, Kloner RA, Przyklenk K. Laser-mediated transmural myocardial channels do not salvage acutely ischemic myocardium. JACC 1993;22:302\u20139.","journal-title":"JACC"},{"key":"BF03044576_CR45","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1161\/01.CIR.93.1.143","volume":"93","author":"P Whittaker","year":"1996","unstructured":"Whittaker P, Rakusan K, Kloner, RA. Transmural channels can protect ischemic tissue. Assessment of long-term myocardial response to laser-and needle-made channels. Circulation 1996:93:143\u201352.","journal-title":"Circulation"}],"container-title":["Herz"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03044576.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03044576\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03044576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T23:44:35Z","timestamp":1558482275000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03044576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,8]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,8]]}},"alternative-id":["BF03044576"],"URL":"https:\/\/doi.org\/10.1007\/bf03044576","relation":{},"ISSN":["0340-9937","1615-6692"],"issn-type":[{"value":"0340-9937","type":"print"},{"value":"1615-6692","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,8]]}}}