{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T23:41:14Z","timestamp":1648942874529},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[1998,5,1]],"date-time":"1998-05-01T00:00:00Z","timestamp":893980800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Klin"],"published-print":{"date-parts":[[1998,5]]},"DOI":"10.1007\/bf03044867","type":"journal-article","created":{"date-parts":[[2009,6,9]],"date-time":"2009-06-09T03:37:19Z","timestamp":1244518639000},"page":"311-318","source":"Crossref","is-referenced-by-count":1,"title":["Junge Patientin mit multiplen arteriellen Verschl\u00fcssen"],"prefix":"10.1007","volume":"93","author":[{"given":"Claudia","family":"Panzer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Brieke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burkhard","family":"Br\u00e4uer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz","family":"Eggemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Martin","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Dieterle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF03044867_CR1","first-page":"309","volume":"38","author":"G Amatucci","year":"1997","unstructured":"Amatucci G, del Mastro G, Iandoli R. Horton giant cell arteritis of the legs \u2014 report of a case. J Cardiovasc Surg 1997;38:309\u201312.","journal-title":"J Cardiovasc Surg"},{"key":"BF03044867_CR2","first-page":"177","volume-title":"Inborn metabolic diseases","author":"G Andria","year":"1996","unstructured":"Andria G, Sebastio G. Homocystinuria due to cystathionine-\u03b2-synthase deficiency and related disorders. In: Fernandez, Saudubray, Berghe van den.: Inborn metabolic diseases, 2nd edn. Berlin-Heidelberg-New York: Springer, 1996:177\u201382.","edition":"2nd edn."},{"key":"BF03044867_CR3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/ajcn\/57.1.47","volume":"57","author":"PJ Becker","year":"1993","unstructured":"Becker PJ, Ubbinck JB, Vermaak WJ, van der Merwe A. Vitamin B-12, vitamin B-6 und folate nutritional status in men with hyperhomocystein\u00e4mie. Am J Clin Nutr 1993;57:47\u201353.","journal-title":"Am J Clin Nutr"},{"key":"BF03044867_CR4","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0950-821X(05)80255-5","volume":"7","author":"C Bergmark","year":"1993","unstructured":"Bergmark C, Mansoor MA, Svardal AM, Swedenborg J, Ueland PM, de Faire U. Hyperhomocysteinemia in patients operated for lower extremity ischaemia below the age of 50 \u2014 effect of smoking and extent of disease. Eur J Vasc Surg 1993;7:391\u20136.","journal-title":"Eur J Vasc Surg"},{"key":"BF03044867_CR5","first-page":"667","volume":"78","author":"RL Bick","year":"1994","unstructured":"Bick RL, Baker WF. The antiphospholipid and thrombosis syndromes. Comm Bleed Clott Disorders 1994;78:667\u201381.","journal-title":"Comm Bleed Clott Disorders"},{"key":"BF03044867_CR6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0049-3848(93)90153-F","volume":"70","author":"T Bienvenu","year":"1993","unstructured":"Bienvenu T, Ankri A, Chadefaux B, Montalescot G, Kamoun P. Elevated total plasma homocysteine, a risk factor for thrombosis. Relation to coagulation and fibrinolytic parameters. Thromb Res 1993;70:123\u20139.","journal-title":"Thromb Res"},{"key":"BF03044867_CR7","first-page":"245","volume":"76","author":"L Broeckaert","year":"1993","unstructured":"Broeckaert L, Ectors N, Ponette E, et al. Mesenteric involvement of thromangiitis obliterans (Buerger\u2019s disease) in a woman. J Belge Radiol 1993;76:245\u20136.","journal-title":"J Belge Radiol"},{"key":"BF03044867_CR8","first-page":"106","volume":"22","author":"P Chauveau","year":"1996","unstructured":"Chauveau P, Chadefaux B, Coude M, Aupetit J, Kamoun P, Jungers P. Long term folic acid (but not pyridoxine) supplementation lowers elevated plasma homocysteine level in chronic renal failure. Miner Electrolyte Metab 1996;22:106\u20139.","journal-title":"Miner Electrolyte Metab"},{"key":"BF03044867_CR9","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1056\/NEJM199104253241701","volume":"324","author":"R Clarke","year":"1991","unstructured":"Clarke R, Daly L, Robinson K, et al. Hyperhomocysteinemia: An independent risk factor for vascular disease. N Engl J Med 1991;324:1149\u201355.","journal-title":"N Engl J Med"},{"key":"BF03044867_CR10","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1093\/ajcn\/63.2.220","volume":"63","author":"ML Cravo","year":"1996","unstructured":"Cravo ML, Gloria LM, Selhub J, et al. Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B12, and vitamin B6 status. Am J Clin Nutr 1996;63:220\u20134.","journal-title":"Am J Clin Nutr"},{"key":"BF03044867_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0049-3848(94)00138-4","volume":"77","author":"B Dahlb\u00e4ck","year":"1995","unstructured":"Dahlb\u00e4ck B. The protein C anticoagulant system: Inherited defects as basis for venous thrombosis. Thromb Res 1995;77:1\u201343.","journal-title":"Thromb Res"},{"key":"BF03044867_CR12","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1073\/pnas.91.4.1396","volume":"91","author":"B Dahlb\u00e4ck","year":"1991","unstructured":"Dahlb\u00e4ck B, Hildebrand B. Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V. Proc Natl Acad Sci USA 1991;91:1396\u20131400.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF03044867_CR13","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1055\/s-2008-1043180","volume":"121","author":"C Diehm","year":"1996","unstructured":"Diehm C, Stammler F. Thrombangiitis obliterans (Buerger-Syndrom). Dtsch Med Wochenschr 1996;121:1543\u20138.","journal-title":"Dtsch Med Wochenschr"},{"key":"BF03044867_CR14","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1093\/jn\/126.suppl_4.1276S","volume":"126","author":"NPB Dudman","year":"1996","unstructured":"Dudman NPB, Wilcken DEL, Wang J, Lynch JF, Macey D, Lundberg P. Disordered methionine\/homocysteine metabolism in premature vascular disease. Its occurence, cofactor therapy and enzymology. J Nutr 1996;126:1276S.","journal-title":"J Nutr"},{"key":"BF03044867_CR15","doi-asserted-by":"crossref","first-page":"747","DOI":"10.7326\/0003-4819-123-10-199511150-00002","volume":"123","author":"I Fermo","year":"1995","unstructured":"Fermo I, D\u2019Angelo SV, Paroni R, Mazzola G, Calori G, D\u2019Angelo A. Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease. Ann Intern Med 1995;123:747\u201353.","journal-title":"Ann Intern Med"},{"key":"BF03044867_CR16","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1161\/01.ATV.14.3.465","volume":"14","author":"DG Franken","year":"1994","unstructured":"Franken DG, Boers GHJ, Blom HJ, Trijbels FJM, Kloppenborg PWC. Treatment of mild hyperhomocysteineania in vascular disease patients. Arterioscler Thromb. 1994;14:465\u201370.","journal-title":"Arterioscler Thromb"},{"key":"BF03044867_CR17","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1001\/jama.1997.03540460039030","volume":"277","author":"IM Graham","year":"1997","unstructured":"Graham IM, Daly LE, Refsum HM, et al. Plasma homocysteine as a risk factor for vascular disease. JAMA 1997;277:1775\u201381.","journal-title":"JAMA"},{"key":"BF03044867_CR18","doi-asserted-by":"crossref","first-page":"1285S","DOI":"10.1093\/jn\/126.suppl_4.1285S","volume":"126","author":"P Harpel","year":"1996","unstructured":"Harpel P, Zhang X, Borth W. Homocysteine and hemostasis: pathogenetic mechanisms predisposing to thrombosis. J Nutr 1996;126:1285S-9S.","journal-title":"J Nutr"},{"issue":"Suppl 2A","key":"BF03044867_CR19","doi-asserted-by":"crossref","first-page":"37S","DOI":"10.1016\/S0002-9343(97)89545-9","volume":"100","author":"G Hunder","year":"1996","unstructured":"Hunder G. Vaskulitis: Diagnosis and therapy. Am J Med 1996;100:Suppl 2A:37S-45S.","journal-title":"Am J Med"},{"key":"BF03044867_CR20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1161\/01.CIR.93.1.7","volume":"93","author":"PF Jacques","year":"1996","unstructured":"Jacques PF, Bostom AG, Williams RR, et al. Relation between folate status, a common mutation in methylenetetrahydrofolat reductase, and plasma homocysteine concentrations. Circulation 1996;93:7\u20139.","journal-title":"Circulation"},{"key":"BF03044867_CR21","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1093\/ajcn\/58.4.468","volume":"58","author":"E Joosten","year":"1993","unstructured":"Joosten E, van den Berg A, Riezler R, et al. Metabolic evidence that deficiencies of vitamin B12, folate and vitamin B6 occur commonly in elderly people. Am J Clin Nutr 1993;58:468\u201376.","journal-title":"Am J Clin Nutr"},{"key":"BF03044867_CR22","doi-asserted-by":"crossref","first-page":"1273S","DOI":"10.1093\/jn\/126.suppl_4.1273S","volume":"126","author":"SS Kang","year":"1996","unstructured":"Kang SS. Treatment of hyperhomocysteinemia. J Nutr 1996;126:1273S-5S.","journal-title":"J Nutr"},{"key":"BF03044867_CR23","first-page":"546","volume":"48","author":"SS Kang","year":"1991","unstructured":"Kang SS, Wong PW, Bock HG, Horwitz A, Grix A. Intermediate hyperhomocysteinemia resulting from compound heterozygosity of methylenetetrahydrofolate reductase mutations. Am J Hum Gen 1991;48:546\u201351.","journal-title":"Am J Hum Gen"},{"key":"BF03044867_CR24","first-page":"536","volume":"48","author":"SS Kang","year":"1991","unstructured":"Kang SS, Wong PW, Susmano A, Sora J, Norusis M, Ruggie N. Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease. Am J Hum Gen 1991;48:536\u201345.","journal-title":"Am J Hum Gen"},{"key":"BF03044867_CR25","doi-asserted-by":"crossref","first-page":"1238S","DOI":"10.1093\/jn\/126.suppl_4.1238S","volume":"126","author":"MR Malinow","year":"1996","unstructured":"Malinow MR. Plasma homocyst(e)ine: A risk factor for arterial occlusive diseases. J Nutr 1996;126:1238S-43S.","journal-title":"J Nutr"},{"key":"BF03044867_CR26","first-page":"111","volume":"56","author":"KS Cully Mc","year":"1969","unstructured":"Mc Cully KS. Vascular pathology of homocysteinemia: implications for pathogenesis of arteriosclerosis. Am J Pathol 1969;56:111\u201328.","journal-title":"Am J Pathol"},{"key":"BF03044867_CR27","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/S0140-6736(96)12049-3","volume":"349","author":"AM Molloy","year":"1997","unstructured":"Molloy AM, Daly SD, Mills JL, et al. Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations. Lancet 1997;349:1591\u20133.","journal-title":"Lancet"},{"key":"BF03044867_CR28","first-page":"1","volume":"37","author":"SH Mudd","year":"1985","unstructured":"Mudd SH, Skovby F, Levy HL, et al. The natural history of homocystinuria due to cystathionine-\u03b2-synthase deficiency. Am J Hum Genet 1985;37:1\u201331.","journal-title":"Am J Hum Genet"},{"key":"BF03044867_CR29","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0140-6736(95)92113-3","volume":"346","author":"HJ Naurath","year":"1995","unstructured":"Naurath HJ, Joosten E, Riezler R, Stabler SP, Allen RH, Lindenbaum J. Effects of vitamin B12, folate and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet 1995;346:85\u20139.","journal-title":"Lancet"},{"key":"BF03044867_CR30","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1001\/jama.1995.03530190040032","volume":"274","author":"O Nygard","year":"1973","unstructured":"Nygard O, Vollset SE, Refsum H, Total plasma homocysteine and cardiovascular risk profile. The Hoordaland Homocysteine study. JAMA 1973;274:1526\u201333.","journal-title":"JAMA"},{"key":"BF03044867_CR31","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/S0741-5214(05)80034-5","volume":"23","author":"K Ouriel","year":"1996","unstructured":"Ouriel K, Green RM, DeWeese JA, Cimino C. Activated protein C resistance: prevalence and implications in peripheral vascular disease. J Vasc Surg 1996;23:46\u201351.","journal-title":"J Vasc Surg"},{"key":"BF03044867_CR32","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/S0140-6736(95)92407-8","volume":"346","author":"IJ Perry","year":"1995","unstructured":"Perry IJ, Refsum H, Morris R, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995;346:1395\u20138.","journal-title":"Lancet"},{"key":"BF03044867_CR33","doi-asserted-by":"crossref","first-page":"2825","DOI":"10.1161\/01.CIR.92.10.2825","volume":"92","author":"K Robinson","year":"1995","unstructured":"Robinson K, Mayer EL, Miller DP, et al. Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factor for coronary artery disease. Circulation 1995;92:2825\u201330.","journal-title":"Circulation"},{"key":"BF03044867_CR34","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1172\/JCI112519","volume":"77","author":"GM Rodgers","year":"1986","unstructured":"Rodgers GM, Kane WH. Activation of endogenous factor V by a homocystein-induced vascular endothelial cell activator. J Clin Invest 1986;77:1909\u201316.","journal-title":"J Clin Invest"},{"key":"BF03044867_CR35","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1056\/NEJM199502023320502","volume":"332","author":"J Selhub","year":"1995","unstructured":"Selhub J, Jacques PF, Bostom AG, et al. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med 1995;332:286\u201391.","journal-title":"N Engl J Med"},{"key":"BF03044867_CR36","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1055\/s-2008-1043162","volume":"121","author":"F Stammler","year":"1996","unstructured":"Stammler F, Diehm C, Hsu E, Stockinger K, Amendt K. Pr\u00e4valenz der Hyperhomocystein\u00e4mie bei der Thrombangiitis obliterans. Dtsch Med Wochenschr 1996;121:1417\u201323.","journal-title":"Dtsch Med Wochenschr"},{"key":"BF03044867_CR37","first-page":"531","volume":"25","author":"Z Tazi","year":"1996","unstructured":"Tazi Z, Cacoub P, Koskas F, et al. Value of an extensive biological study in venous or arterial thromboses. Presse Med 1996;25:531\u20136.","journal-title":"Presse Med"},{"issue":"Suppl","key":"BF03044867_CR38","first-page":"IV-1","volume":"84","author":"The European working group on critical limb ischaemia","year":"1991","unstructured":"The European working group on critical limb ischaemia: Second European consensus document on chronic critical leg ischemia. Circulation 1991;84:Suppl:IV-1\u2013IV-22.","journal-title":"Circulation"},{"key":"BF03044867_CR39","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1007\/BF00180030","volume":"71","author":"JB Ubbink","year":"1993","unstructured":"Ubbink JB, van der Merwe A, Vermmak WJ, Delport R. Hyperhomocysteinemia and the response to vitamin supplementation. Clin Invest 1993;71:993\u20138.","journal-title":"Clin Invest"},{"key":"BF03044867_CR40","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/0741-5214(94)90230-5","volume":"20","author":"M Berg van den","year":"1994","unstructured":"van den Berg M, Franken DG, Boers GHJ, et al. Combined vitamin B6 plus folic acid therapy in young patients with arteriosclerosis and hyperhomocysteinemia. J Vasc Surg 1994;20:933\u20134.","journal-title":"J Vasc Surg"}],"container-title":["Medizinische Klinik"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03044867.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03044867\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03044867","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T23:49:35Z","timestamp":1558482575000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03044867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1998,5]]}},"alternative-id":["BF03044867"],"URL":"https:\/\/doi.org\/10.1007\/bf03044867","relation":{},"ISSN":["0723-5003","1615-6722"],"issn-type":[{"value":"0723-5003","type":"print"},{"value":"1615-6722","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,5]]}}}