{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T14:59:43Z","timestamp":1772204383849,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Toxicol."],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1007\/bf03161197","type":"journal-article","created":{"date-parts":[[2009,8,28]],"date-time":"2009-08-28T12:20:52Z","timestamp":1251462052000},"page":"173-179","source":"Crossref","is-referenced-by-count":35,"title":["Cardiotoxicity after massive amantadine overdose"],"prefix":"10.1007","volume":"4","author":[{"given":"Michael D.","family":"Schwartz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish M.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad N.","family":"Kazzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent W.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF03161197_CR1","first-page":"1175","volume":"25","author":"DK Strong","year":"1991","unstructured":"Strong DK, Eisenstat DD, Bryson SM, Sitar DS, Arbus GS. Amantadine neurotoxicity in a pediatric patient with renal insufficiency.Ann Pharmacother 1991; 25: 1175\u20131177.","journal-title":"Ann Pharmacother"},{"issue":"6","key":"BF03161197_CR2","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S0196-0644(05)82473-4","volume":"19","author":"ER Snoey","year":"1989","unstructured":"Snoey ER, Bessen HA. Acute psychosis after amantadine overdose.Ann Emerg Med 1989; 19(6): 668\u2013670.","journal-title":"Ann Emerg Med"},{"key":"BF03161197_CR3","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/0003-9993(93)90072-I","volume":"74","author":"GJ Macchio","year":"1993","unstructured":"Macchio GJ, Ito V, Sahgal V. Amantadine-induced coma.Arch Phys Med Rehabil 1993; 74: 1119\u20131120.","journal-title":"Arch Phys Med Rehabil"},{"issue":"1","key":"BF03161197_CR4","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0022-3476(79)80111-0","volume":"95","author":"CD Berkowitz","year":"1979","unstructured":"Berkowitz CD. Treatment of acute amantadine toxicity with physostigmine.J Pediatr 1979; 95(1): 144\u2013145.","journal-title":"J Pediatr"},{"issue":"2","key":"BF03161197_CR5","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/0002-9343(84)90728-9","volume":"77","author":"M Sartori","year":"1984","unstructured":"Sartori M, Pratt CM, Young JB. Torsade de pointe: malignant cardiac arrhythmia induced by amantadine poisoning.Am J Med 1984; 77(2): 388\u2013391.","journal-title":"Am J Med"},{"issue":"8","key":"BF03161197_CR6","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1177\/070674378603100814","volume":"31","author":"PE Cook","year":"1986","unstructured":"Cook PE, Dermer SW, McGurk T. Fatal overdose with amantadine.Can J Psychiatry 1986; 31(8): 757\u2013758.","journal-title":"Can J Psychiatry"},{"issue":"2","key":"BF03161197_CR7","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1176\/ajp.145.2.267","volume":"145","author":"DM Simpson","year":"1988","unstructured":"Simpson DM, Ramos F, Ramirez LF. Death of a psychiatric patient from amantadine poisoning.Am J Psych 1988; 145(2): 267\u2013268.","journal-title":"Am J Psych"},{"issue":"6","key":"BF03161197_CR8","first-page":"463","volume":"29","author":"CR Brown","year":"1987","unstructured":"Brown CR, Hernandez S, Kelly MT. Hyperthermia and death from amantadine overdose.Vet Hum Toxicol 1987; 29(6): 463.","journal-title":"Vet Hum Toxicol"},{"issue":"2","key":"BF03161197_CR9","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/00006565-199104000-00007","volume":"7","author":"L Pimentel","year":"1991","unstructured":"Pimentel L, Hughes B. Amantadine toxicity presenting with complex ventricular ectopy and hallucinations.Pediatr Emerg Care 1991; 7(2): 89\u201392.","journal-title":"Pediatr Emerg Care"},{"issue":"3","key":"BF03161197_CR10","first-page":"355","volume":"23","author":"CC Yang","year":"1997","unstructured":"Yang CC, Deng JF. Anticholinergic syndrome with severe rhabdomyolysis: an unusual feature of amantadine toxicity.Intensive Care Med 1997; 23(3): 355\u2013356.","journal-title":"Intensive Care Med"},{"key":"BF03161197_CR11","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1001\/archneur.1971.00490010055008","volume":"25","author":"S Fahn","year":"1971","unstructured":"Fahn S, Craddock G, Kumin G. Acute toxic psychosis from suicidal overdosage of amantadine.Arch Neurol 1971; 25: 45\u201348.","journal-title":"Arch Neurol"},{"issue":"25","key":"BF03161197_CR12","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1016\/0024-3205(94)00387-4","volume":"55","author":"KW Lange","year":"1994","unstructured":"Lange KW, Riederer P. Glutaminergic drugs in Parkinson\u2019s disease.Life Sci 1994; 55(25\u20136): 2067\u20132075.","journal-title":"Life Sci"},{"key":"BF03161197_CR13","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1161\/01.RES.51.6.722","volume":"51","author":"JJ Salata","year":"1982","unstructured":"Salata JJ, Jalife J, Megna JL, Alperovich G. Amantadine-induced diastolic depolarization and automaticity in ventricular muscle.Circ Res 1982; 51: 722\u2013732.","journal-title":"Circ Res"},{"key":"BF03161197_CR14","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1161\/01.RES.65.4.880","volume":"65","author":"M Hiraoka","year":"1989","unstructured":"Hiraoka M, Hirano Y, Kawano S, Fan Z, Sawanobori T. Amantadine-induced afterpotentials and automaticity in guinea pig ventricular myocytes.Circ Res 1989; 65: 880\u2013893.","journal-title":"Circ Res"},{"key":"BF03161197_CR15","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2165\/00003088-198814010-00003","volume":"14","author":"FY Aoki","year":"1988","unstructured":"Aoki FY, Sitar DS. Clinical pharmacokinetics of amantadine hydrochloride.Clin Pharmacokinetic 1988; 14: 35\u201351.","journal-title":"Clin Pharmacokinetic"},{"key":"BF03161197_CR16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/00002826-198406000-00005","volume":"7","author":"P Liu","year":"1984","unstructured":"Liu P, Cheng PJ, Ing TS, Daugirdas JT, Jeevanandhan R. In vitro binding of amantadine to plasma proteins.Clin Neuropharmacol 1984; 7: 149\u2013151.","journal-title":"Clin Neuropharmacol"}],"container-title":["Journal of Medical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03161197.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03161197\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03161197","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T02:36:29Z","timestamp":1558492589000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03161197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["BF03161197"],"URL":"https:\/\/doi.org\/10.1007\/bf03161197","relation":{},"ISSN":["1556-9039","1937-6995"],"issn-type":[{"value":"1556-9039","type":"print"},{"value":"1937-6995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}