{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T18:12:40Z","timestamp":1772907160080,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin. Drug Investig."],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1007\/bf03256939","type":"journal-article","created":{"date-parts":[[2013,3,3]],"date-time":"2013-03-03T01:34:28Z","timestamp":1362274468000},"page":"135-141","source":"Crossref","is-referenced-by-count":12,"title":["Safety of Recombinant Human Thrombopoietin in Adults after Related Donor Haploidentical Haematopoietic Stem Cell Transplantation"],"prefix":"10.1007","volume":"31","author":[{"given":"Dai-Hong","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Jun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan-Ping","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,8,24]]},"reference":[{"key":"BF03256939_CR1","doi-asserted-by":"crossref","first-page":"4054","DOI":"10.1182\/blood.V86.11.4054.bloodjournal86114054","volume":"86","author":"J. Chen","year":"1995","unstructured":"Chen J, Herceg-Harjacek L, Groopman JE, et al. Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. Blood 1995; 86: 4054\u201362","journal-title":"Blood"},{"key":"BF03256939_CR2","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/S0140-6736(96)04471-6","volume":"348","author":"R.L. Basser","year":"1996","unstructured":"Basser RL, Rasko JE, Clarke K, et al. Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer. Lancet 1996; 348: 1279\u201381","journal-title":"Lancet"},{"issue":"Suppl.1","key":"BF03256939_CR3","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/stem.5530140734","volume":"14","author":"R.A. Nash","year":"1996","unstructured":"Nash RA, Gooley T, Davis C, et al. The problem of thrombocytopenia after hematopoietic stem cell transplantation. Stem Cells 1996; 14Suppl. 1: 261\u201373","journal-title":"Stem Cells"},{"key":"BF03256939_CR4","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.bbmt.2009.02.001","volume":"15","author":"Y.J. Chang","year":"2009","unstructured":"Chang YJ, Xu LP, Liu DH, et al. Platelet engraftment in patients with hematologic malignancies following unmanipulated haploidentical blood and marrow transplantation: effects of CD34+ cell dose and disease status. Biol Blood Marrow Transplant 2009; 15: 632\u20138","journal-title":"Biol Blood Marrow Transplant"},{"key":"BF03256939_CR5","first-page":"3118","volume":"89","author":"R.L. Basser","year":"1997","unstructured":"Basser RL, Rasko JE, Clarke K, et al. Randomized, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor with filgrastim after dose-intensive chemotherapy in patients with advanced cancer. Blood 1997; 89: 3118\u201328","journal-title":"Blood"},{"key":"BF03256939_CR6","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/sj.bmt.1702772","volume":"27","author":"S.N. Wolff","year":"2001","unstructured":"Wolff SN, Herzig R, Lynch J, et al. Recombinant human thrombopoietin (rhTPO) after autologous bone marrow transplantation: a phase I pharmacokinetic and pharmacodynamic study. Bone Marrow Transplant 2001; 27: 261\u20138","journal-title":"Bone Marrow Transplant"},{"key":"BF03256939_CR7","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1083-8791(00)70049-8","volume":"6","author":"R.A. Nash","year":"2000","unstructured":"Nash RA, Kurzrock R, Dipersio J, et al. A phase I trial of recombinant human thrombopoietin in patients with delayed platelets recovery after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2000; 6: 25\u201334","journal-title":"Biol Blood Marrow Transplant"},{"key":"BF03256939_CR8","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/sj.bmt.1705445","volume":"38","author":"X.J. Huang","year":"2006","unstructured":"Huang XJ, Liu DH, Liu KY, et al. Haploidentical hematopoietic stem cell transplantation without in vitro T-cell depletion for the treatment of hematologic malignancies. Bone Marrow Transplant 2006; 38: 291\u20137","journal-title":"Bone Marrow Transplant"},{"issue":"Suppl.1","key":"BF03256939_CR9","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bbmt.2008.10.019","volume":"15","author":"X.J. Huang","year":"2009","unstructured":"Huang XJ, Liu DH, Liu KY, et al. Treatment of acute leukaemia with unmanipulated HLA-mismatched\/haploidentical blood and bone marrow transplantation. Biol Blood and Marrow Transplant 2009; 15Suppl. 1: 91\u20134","journal-title":"Biol Blood and Marrow Transplant"},{"key":"BF03256939_CR10","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1182\/blood.V73.4.1054.1054","volume":"73","author":"C. Anasetti","year":"1989","unstructured":"Anasetti C, Rybka W, Sullivan KM, et al. Graft-v-host disease is associated with autoimmune-like thrombocytopenia. Blood 1989; 73: 1054\u20138","journal-title":"Blood"},{"key":"BF03256939_CR11","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1182\/blood.V77.8.1837.1837","volume":"77","author":"S.N. Rabinowe","year":"1991","unstructured":"Rabinowe SN, Soiffer RJ, Tarbell NJ, et al. Hemolyticuremic syndrome following bone marrow transplantation in adults for hematologic malignancies. Blood 1991; 77: 1837\u201344","journal-title":"Blood"},{"key":"BF03256939_CR12","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/00005792-199203000-00002","volume":"71","author":"T.R. Klumpp","year":"1992","unstructured":"Klumpp TR, Block CC, Caligiuri MA, et al. Immunemediated cytopenia following bone marrow transplantation: case reports and review of the literature. Medicine 1992; 71: 73\u201383","journal-title":"Medicine"},{"key":"BF03256939_CR13","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1182\/blood.V86.3.971.971","volume":"86","author":"T.R. Ulich","year":"1995","unstructured":"Ulich TR, del Castillo J, Yin S, et al. Megakaryocyte growth and development factor ameliorates carboplatin-induced thrombocytopenia in mice. Blood 1995; 86: 971\u20136","journal-title":"Blood"},{"key":"BF03256939_CR14","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1182\/blood.V88.1.366.366","volume":"88","author":"G. Molineux","year":"1996","unstructured":"Molineux G, Hartley CA, McElroy P, et al. Megakaryocyte growth and development factor stimulates enhanced platelets recovery in mice after bone marrow transplantation. Blood 1996 15; 88: 509\u201314","journal-title":"Blood"},{"key":"BF03256939_CR15","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1182\/blood.V90.7.2565","volume":"90","author":"K.J. Neelis","year":"1997","unstructured":"Neelis KJ, Hartong SC, Egeland T, et al. The efficacy of single-dose administration of thrombopoietin with coad-ministration of either granulocyte\/macrophage or granulocyte colony-stimulating factor in myelosuppressed rhesus monkeys. Blood 1997; 90: 2565\u201373","journal-title":"Blood"},{"key":"BF03256939_CR16","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1056\/NEJM199702063360603","volume":"336","author":"M. Fanucchi","year":"1997","unstructured":"Fanucchi M, Glaspy J, Crawford J, et al. Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelets counts after chemotherapy for lung cancer. N Engl J Med 1997; 336: 404\u20139","journal-title":"N Engl J Med"}],"container-title":["Clinical Drug Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03256939.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03256939\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03256939","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T03:55:28Z","timestamp":1595476528000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03256939"}},"subtitle":["A Pilot Study"],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["BF03256939"],"URL":"https:\/\/doi.org\/10.1007\/bf03256939","relation":{},"ISSN":["1173-2563","1179-1918"],"issn-type":[{"value":"1173-2563","type":"print"},{"value":"1179-1918","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}