{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T23:11:55Z","timestamp":1774566715607,"version":"3.50.1"},"reference-count":184,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1989,12,1]],"date-time":"1989-12-01T00:00:00Z","timestamp":628473600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Toxicol Adverse Drug Exp"],"published-print":{"date-parts":[[1989,12]]},"DOI":"10.1007\/bf03259926","type":"journal-article","created":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T11:37:39Z","timestamp":1354189059000},"page":"452-467","source":"Crossref","is-referenced-by-count":29,"title":["Drug-Induced Ototoxicity"],"prefix":"10.1007","volume":"4","author":[{"given":"May Y.","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Schacht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,11,27]]},"reference":[{"key":"BF03259926_CR1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1177\/31.2.6300219","volume":"31","author":"SK Aggarwal","year":"1983","unstructured":"Aggarwal SK, Niroomand-Rad I. Effect of cisplatin on the plasma membrane phosphatase activities in ascites sarcoma-180 cells: a cytochemical study. Journal of Histochemistry and Cytochemistry 31: 307\u2013317, 1983","journal-title":"Journal of Histochemistry and Cytochemistry"},{"key":"BF03259926_CR2","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S0196-0709(86)80050-3","volume":"7","author":"M Anniko","year":"1986","unstructured":"Anniko M, Sobin A. Cis-platin: evaluation of its ototoxic potential. American Journal of Otolaryngology 7: 276\u2013293, 1986","journal-title":"American Journal of Otolaryngology"},{"key":"BF03259926_CR3","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0196-0709(82)80020-3","volume":"3","author":"M Anniko","year":"1982","unstructured":"Anniko M, Takada A, Schacht J. Comparative ototoxicities of gentamicin and netilmicin in three model systems. American Journal of Otolaryngology 3: 422\u2013433, 1982","journal-title":"American Journal of Otolaryngology"},{"key":"BF03259926_CR4","doi-asserted-by":"crossref","first-page":"300","DOI":"10.3109\/00016487909126424","volume":"87","author":"JM Aran","year":"1979","unstructured":"Aran JM, Cazals Y, Erre JP, Guilhaume A. Conflicting electrophysiological and anatomical data from drug impaired guinea pig cochleas. Acta Otolaryngologica 87: 300\u2013309, 1979","journal-title":"Acta Otolaryngologica"},{"key":"BF03259926_CR5","first-page":"3","volume":"390","author":"JM Aran","year":"1982","unstructured":"Aran JM, Erre JP, Guilhaume A, Aurousseau C. The comparative ototoxicities of gentamicin, tobramycin and dibekacin in the guinea pig. Acta Otolaryngologica 390 (Suppl.): 3\u201330, 1982","journal-title":"Acta Otolaryngologica"},{"key":"BF03259926_CR6","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1128\/AAC.23.1.74","volume":"23","author":"GR Aronoff","year":"1983","unstructured":"Aronoff GR, Pottratz ST, Brier ME, et al. Aminoglycoside accumulation kinetics in rat renal parenchyma. Antimicrobial Agents and Chemotherapeutics 23: 74\u201378, 1983","journal-title":"Antimicrobial Agents and Chemotherapeutics"},{"key":"BF03259926_CR7","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3109\/00016488109133242","volume":"92","author":"J Aursnes","year":"1981","unstructured":"Aursnes J. Vestibular damage from chlorhexidine in guinea pigs. Acta Oto-Laryngologica 92: 89\u2013100, 1981","journal-title":"Acta Oto-Laryngologica"},{"key":"BF03259926_CR8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.3109\/00016488209130875","volume":"93","author":"J Aursnes","year":"1982","unstructured":"Aursnes J. Ototoxic effect of iodine disinfectants. Acta Otolaryngologica 93: 219\u2013226, 1982","journal-title":"Acta Otolaryngologica"},{"key":"BF03259926_CR9","unstructured":"Axelsson A. Comparative anatomy and development of cochlear blood vessels. Association for Research and Otolaryngology 11th Midwinter Meeting, Clearwater Beach, Florida, January 31\u2013February 4, 1988. Abstract no. 81, p. 68, 1988"},{"key":"BF03259926_CR10","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF00454231","volume":"228","author":"D Bagger-Sj\u00f6b\u00e4ck","year":"1980","unstructured":"Bagger-Sj\u00f6b\u00e4ck D, Filipek CS, Schacht J. Characteristics and drug responses of cochlear and vestibular adenylate cyclase. Archives of Otorhinolaryngology 228: 217\u2013222, 1980","journal-title":"Archives of Otorhinolaryngology"},{"key":"BF03259926_CR11","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3109\/00206097309071648","volume":"12","author":"JC Ballantyne","year":"1973","unstructured":"Ballantyne JC. Ototoxicity: a clinical review. Audiology 12: 325\u2013336, 1973","journal-title":"Audiology"},{"key":"BF03259926_CR12","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF00163711","volume":"6","author":"CC Baranak","year":"1988","unstructured":"Baranak CC, Wetmore RF, Packer RJ. Cis-platinum ototoxicity after radiation treatment: an animal model. Journal of Neuro-Oncology 6: 261\u2013267, 1988","journal-title":"Journal of Neuro-Oncology"},{"key":"BF03259926_CR13","first-page":"1215","volume":"70","author":"JF Belliveau","year":"1986","unstructured":"Belliveau JF, Posner MR, Ferrari L, et al. Cisplatin administered as a continuous 5-day infusion: plasma platinum levels and urine platinum excretion. Cancer Treatment Reports 70: 1215\u20131217, 1986","journal-title":"Cancer Treatment Reports"},{"key":"BF03259926_CR14","first-page":"1515","volume":"63","author":"RJ Belt","year":"1979","unstructured":"Belt RJ, Himmelstein KJ, Patton TF, et al. Pharmacokinetics of non-protein-bound platinum species following administration of cis-dichlorodiamine platinum (II). Cancer Treatment Reports 63: 1515\u20131521, 1979","journal-title":"Cancer Treatment Reports"},{"key":"BF03259926_CR15","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1128\/AAC.22.3.508","volume":"22","author":"WM Bennett","year":"1982","unstructured":"Bennett WM, Elliott WC, Houghton DC, et al. Reduction of experimental gentamicin nephrotoxicity in rats by dietary calcium loading. Antimicrobial Agents and Chemotherapy 22: 508\u2013512, 1982","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF03259926_CR16","doi-asserted-by":"crossref","first-page":"407","DOI":"10.3109\/00016488009127156","volume":"89","author":"SK Bosher","year":"1980","unstructured":"Bosher SK. The nature of the ototoxic actions of ethacrynic acid upon the mammalian endolymph system. I. Functional aspects. Acta Otolaryngologica 89: 407\u2013418, 1980","journal-title":"Acta Otolaryngologica"},{"key":"BF03259926_CR17","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1128\/AAC.27.5.812","volume":"27","author":"ME Brier","year":"1985","unstructured":"Brier ME, Mayer PR, Brier RA, et al. Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nehrotoxicities. Antimicrobial Agents and Chemotherapy 27: 812\u2013816, 1985","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF03259926_CR18","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1128\/AAC.25.2.168","volume":"25","author":"N Brion","year":"1984","unstructured":"Brion N, Barge J, Godefray I, et al. Gentamicin, netilmicin, dibekacin, and amikacin nephrotoxicity and its relationship to tubular reabsorption in rabbits. Antimicrobial Agents and Chemotherapy 25: 168\u2013172, 1984","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF03259926_CR19","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/mpo.2950160517","volume":"16","author":"P Brock","year":"1988","unstructured":"Brock P, Pritchard J, Bellman S, Pinkerton CR. Ototoxicity of high-dose cis-platinum in children. Medical and Pediatric Oncology 16: 368\u2013369, 1988","journal-title":"Medical and Pediatric Oncology"},{"key":"BF03259926_CR20","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/0041-008X(75)90162-3","volume":"31","author":"RD Brown","year":"1975","unstructured":"Brown RD. Comparison of the cochlear toxicity of sodium ethacrynate, furosemide, and the cysteine adduct of sodium ethacrynate in cats. Toxicology and Applied Pharmacology 31: 270\u2013282, 1975","journal-title":"Toxicology and Applied Pharmacology"},{"key":"BF03259926_CR21","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0041-008X(72)90286-4","volume":"22","author":"RD Brown","year":"1972","unstructured":"Brown RD, McElwee Jr TT. Effects of intra-arterially and intravenously administered ethacrynic acid and furosemide on cochlear NI in cats. Toxicology and Applied Pharmacology 22: 589\u2013594, 1972","journal-title":"Toxicology and Applied Pharmacology"},{"key":"BF03259926_CR22","first-page":"419","volume-title":"The aminoglycosides. Microbiology, clinical use and toxicology","author":"RE Brummett","year":"1982","unstructured":"Brummett RE, Fox KE. Studies of aminoglycoside ototoxicity in animal models. In Whelton & Neu (Eds) The aminoglycosides. Microbiology, clinical use and toxicology, pp. 419\u2013451, Dekker, New York, 1982"},{"key":"BF03259926_CR23","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1288\/00005537-197608000-00009","volume":"86","author":"RE Brummett","year":"1976","unstructured":"Brummett RE, Harris RF, Lindgren JA. Detection of ototoxicity from drugs applied topically to the middle ear space. Laryngoscope 86: 1177\u20131187, 1976","journal-title":"Laryngoscope"},{"key":"BF03259926_CR24","unstructured":"Brummett RE, Morrison R, Matthews J. Possible site of action of erythromycin ototoxicity in the human. Association for Research in Otolaryngology 12th Midwinter Meeting, St Petersburg Beach, Florida, February 5\u20139, 1989. Abstract no. 220, p. 185, 1989"},{"key":"BF03259926_CR25","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3109\/00016487509121305","volume":"80","author":"RE Brummett","year":"1975","unstructured":"Brummett RE, Traynor J, Brown R, Himes DL. Cochlear damage resulting from kanamycin and furosemide. Acta Oto-Laryngologica 80: 86\u201392, 1975","journal-title":"Acta Oto-Laryngologica"},{"key":"BF03259926_CR26","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/ki.1973.121","volume":"4","author":"M Burg","year":"1973","unstructured":"Burg M, Green N. Effects of ethacrynic acid on the thick ascending limb of Henle\u2019s loop. Kidney International 4: 301\u2013308, 1973","journal-title":"Kidney International"},{"key":"BF03259926_CR27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00007691-198901000-00008","volume":"11","author":"BC Carlstedt","year":"1989","unstructured":"Carlstedt BC, Uaamnuichai M, Day RB, et al. Aminoglycoside dosing in pediatric patients. Therapeutic Drug Monitoring 11: 38\u201343, 1989","journal-title":"Therapeutic Drug Monitoring"},{"key":"BF03259926_CR28","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0378-5955(88)90139-6","volume":"36","author":"Y Cazals","year":"1988","unstructured":"Cazals Y, Li XQ, Aurousseau C, Didier A. Acute effects of noradrenalin related vasoactive agents on the ototoxicity of aspirin: an experimental study in the guinea pig. Hearing Research 36: 89\u201396, 1988","journal-title":"Hearing Research"},{"key":"BF03259926_CR29","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1017\/S0022215100101161","volume":"100","author":"SD Comis","year":"1986","unstructured":"Comis SD, Rhys-Evans PH, Osborne MP, et al. Early morphological and chemical changes induced by cisplatin in the guinea pig organ of Corti. Journal of Laryngology and Otology 100: 1375\u20131383, 1986","journal-title":"Journal of Laryngology and Otology"},{"key":"BF03259926_CR30","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/0002-8703(73)90434-1","volume":"85","author":"LB Cooperman","year":"1973","unstructured":"Cooperman LB, Rubin IL. Toxicity of ethacrynic acid and furosemide. American Heart Journal 85: 831\u2013834, 1973","journal-title":"American Heart Journal"},{"key":"BF03259926_CR31","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1093\/jac\/23.3.441","volume":"23","author":"RJ Courcol","year":"1989","unstructured":"Courcol RJ, Pinkas M, Martin GR. A seven year survey of antibiotic susceptibility and its relationship with usage. Journal of Antimicrobial Chemotherapy 23: 441\u2013451, 1989","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF03259926_CR32","first-page":"764","volume":"20","author":"R Cramer","year":"1986","unstructured":"Cramer R. Erythromycin ototoxicity. Drug Intelligence and Clinical Pharmacy 20: 764\u2013765, 1986","journal-title":"Drug Intelligence and Clinical Pharmacy"},{"key":"BF03259926_CR33","first-page":"2956","volume-title":"Otolaryngology \u2014head and neck surgery, Vol. IV","year":"1986","unstructured":"Cummings and Harker et al. (Eds). Otolaryngology \u2014head and neck surgery, Vol. IV, pp. 2956\u20133156, CV Mosby Company, St Louis, 1986"},{"key":"BF03259926_CR34","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2165\/00003088-197904040-00002","volume":"4","author":"RE Cutler","year":"1979","unstructured":"Cutler RE, Blair AD. Clinical pharmacokinetics of frusemide. Clinical Pharmacokinetics 4: 279\u2013296, 1979","journal-title":"Clinical Pharmacokinetics"},{"key":"BF03259926_CR35","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1128\/AAC.8.1.58","volume":"8","author":"JG Dahlgren","year":"1975","unstructured":"Dahlgren JG, Anderson ET, Hewitt WL. Gentamicin blood levels: a guide to nephrotoxicity. Antimicrobial Agents and Chemotherapy 8: 58\u201362, 1975","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF03259926_CR36","first-page":"781","volume":"83","author":"J Darrouzet","year":"1962","unstructured":"Darrouzet J, de Lima Sobrinho E. Oreille interne, kanamycine et traumatisme acoustique, \u00e9tude \u00e9xperimentale. Revue de Laryngologie Otologie Rhinologie 83: 781\u2013806, 1962","journal-title":"Revue de Laryngologie Otologie Rhinologie"},{"key":"BF03259926_CR37","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1093\/jac\/14.3.291","volume":"14","author":"RR Davis","year":"1984","unstructured":"Davis RR, Brummett RE, Bendrick TW, Hirnes DL. Dissociation of maximum concentrations of kanamycin in plasma and perilymph from other ototoxic effects. Journal of Antimicrobial Chemotherapy 14: 291\u2013302, 1984","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF03259926_CR38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1288\/00005537-197501000-00001","volume":"85","author":"VS Dayal","year":"1975","unstructured":"Dayal VS, Barok WG. Cochlear changes from noise, kanamycin, and aging. Laryngoscopy 85 (Suppl.): 1\u201318, 1975","journal-title":"Laryngoscopy"},{"key":"BF03259926_CR39","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0378-5955(88)90038-X","volume":"35","author":"JCMJ Groot de","year":"1988","unstructured":"de Groot JCMJ, Veldman JE. Early effects of genamicin on inner ear glycocalyx cytochemistry. Hearing Research 35: 39\u201346, 1988","journal-title":"Hearing Research"},{"key":"BF03259926_CR40","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1128\/AAC.30.1.96","volume":"30","author":"D Dulon","year":"1986","unstructured":"Dulon D, Aran JM, Zajic G, Schacht J. Comparative uptake of gentamicin, netilmicin and amikacin in the guinea pig cochlea and vestibule. Antimicrobial Agents and Chemotherapy 30: 96\u2013100, 1986","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF03259926_CR41","unstructured":"Dulon D, Zajic G, Schacht J. Intracellular ionized calcium in single outer hair cells during stimulation in vitro. Association for Research in Otolaryngology 12th Midwinter Meeting, St Petersburg Beach, Florida, February 5\u20139, 1989"},{"key":"BF03259926_CR42","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF00647237","volume":"23","author":"M Dumas","year":"1989","unstructured":"Dumas M, de Gislain C, d\u2019Athis P,et al. Evaluation of the effect of furosemide on ultrafilterable platinum kinetics in patients treated with cis-diamminedichloroplatinum. Cancer Chemotherapy and Pharmacology 23: 37\u201340, 1989","journal-title":"Cancer Chemotherapy and Pharmacology"},{"key":"BF03259926_CR43","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0300-483X(87)90060-6","volume":"47","author":"MS Engineer","year":"1987","unstructured":"Engineer MS, Ho DW, Khokhar AR, et al. A comparison of the effects of cisplatin and N-methyliminodiacetato-(1,2-diaminocyclohexan)-platinum (II) on renal function and gentamicin excretion in rats. Toxicology 47: 307\u2013315, 1987","journal-title":"Toxicology"},{"key":"BF03259926_CR44","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0090-6980(85)90082-6","volume":"29","author":"B Escoubet","year":"1985","unstructured":"Escoubet B, Amsallem P, Ferrary E, Tran Ba Huy P. Prostaglandin synthesis by the cochlea of the guinea pig. Influence of aspirin, gentamicin and acoustic stimulation. Prostaglandins 29: 589\u2013599, 1985","journal-title":"Prostaglandins"},{"issue":"6B","key":"BF03259926_CR45","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0002-9343(86)90477-8","volume":"80","author":"DA Evans","year":"1986","unstructured":"Evans DA, Buring J, Mayrent S, et al. Qualitative overview of randomized trials of aminoglycosides. American Journal of Medicine 80 (Suppl. 6B): 39\u201343, 1986","journal-title":"American Journal of Medicine"},{"key":"BF03259926_CR46","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1113\/jphysiol.1982.sp014379","volume":"331","author":"EF Evans","year":"1982","unstructured":"Evans EF, Kline R. The effects of intracochlear and systemic furosemide on the properties of single cochlear nerve fibers in the cat. Journal of Physiology 331: 409\u2013427, 1982","journal-title":"Journal of Physiology"},{"key":"BF03259926_CR47","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/9780470720677.ch7","volume-title":"CIBA Foundation Symposium 85","author":"EF Evans","year":"1981","unstructured":"Evans EF, Wilson JP, Borerwe TA. Animal models of tinnitus. In CIBA Foundation Symposium 85, pp. 108\u2013129, Pitman, London, 1981"},{"key":"BF03259926_CR48","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0378-5955(86)90116-4","volume":"23","author":"LD Fechter","year":"1986","unstructured":"Fechter LD, Young JS, Nuttall AL. Trimethyltin ototoxicity: evidence for a cochlear site of injury. Hearing Research 23: 275\u2013282, 1986","journal-title":"Hearing Research"},{"key":"BF03259926_CR49","doi-asserted-by":"crossref","first-page":"S200","DOI":"10.1093\/infdis\/134.Supplement_1.S200","volume":"134","author":"P Federspil","year":"1976","unstructured":"Federspil P, Sch\u00e4tzle W, Tiesler E. Pharmacokinetics and ototoxicity of gentamicin, tobramycin, and amikacin. Journal of Infectious Diseases 134 (Suppl.): S200\u2013S205, 1976","journal-title":"Journal of Infectious Diseases"},{"key":"BF03259926_CR50","first-page":"1","volume":"90","author":"WE Fee Jr","year":"1980","unstructured":"Fee Jr WE. Aminoglycoside ototoxicity in the human. Laryngoscope 90 (Suppl.): 1\u201319, 1980","journal-title":"Laryngoscope"},{"key":"BF03259926_CR51","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/jac\/7.1.81","volume":"7","author":"IW Fong","year":"1981","unstructured":"Fong IW, Fenton RS, Bird R. Comparative toxicity of gentamicin versus tobramycin: randomized prospective study. Journal of Antimicrobial Chemotherapy 7: 81\u201388, 1981","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF03259926_CR52","first-page":"39","volume":"35","author":"A Forge","year":"1985","unstructured":"Forge A. Outer hair cell loss and supporting cell expansion following chronic gentamicin treatment. Hearing Research 35: 39\u201346, 1985","journal-title":"Hearing Research"},{"key":"BF03259926_CR53","unstructured":"Forge A, Davies JP, Zajic G, et al. Gentamicin alters membrane structure: freeze-fracture studies of hair cells and liposomes. Association for Research in Otolaryngology 12th Midwinter Meeting, St Petersburg Beach, Florida, February 5\u20139, 1989. Abstract no. 124, p. 109, 1989a"},{"key":"BF03259926_CR54","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0378-5955(89)90035-X","volume":"37","author":"A Forge","year":"1989","unstructured":"Forge A, Zajic G, Davies S, et al. Gentamicin alters membrane structure as shown by freeze-fracture of liposomes. Hearing Research 37: 129\u2013140, 1989b","journal-title":"Hearing Research"},{"key":"BF03259926_CR55","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3109\/00016487909126389","volume":"87","author":"KE Fox","year":"1979","unstructured":"Fox KE, Brummett RE. The relationship between cytotoxicity of kanamycin and ethacrynic acid for mammalian cells in vitro and their ototoxicity in vivo. Acta Otolaryngologica 87: 72\u201378, 1979","journal-title":"Acta Otolaryngologica"},{"key":"BF03259926_CR56","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1128\/AAC.23.6.897","volume":"23","author":"JM Gatell","year":"1983","unstructured":"Gatell JM, San Miguel JG, Zamora L, et al. Comparison of nephrotoxicity and auditory toxicity of tobramycin and amikacin. Antimicrobial Agents and Chemotherapy 23: 897\u2013901, 1983","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF03259926_CR57","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0041-008X(73)80012-2","volume":"25","author":"WJ Goldman","year":"1973","unstructured":"Goldman WJ, Bielinski TC, Mattis PA. Cochlear microphonic potential response of the dog to diuretic compounds. Toxicology and Applied Pharmacology 25: 259\u2013266, 1973","journal-title":"Toxicology and Applied Pharmacology"},{"key":"BF03259926_CR58","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1002\/1097-0142(197704)39:4<1362::AID-CNCR2820390403>3.0.CO;2-N","volume":"39","author":"JC Gonzalez-Vitale","year":"1977","unstructured":"Gonzalez-Vitale JC, Hayes DM, Cvitkovic E, Sternberg SS. The renal pathology in clinical trials of cis-platinum (II) diamminedichloride. Cancer 39: 1362, 1977","journal-title":"Cancer"},{"key":"BF03259926_CR59","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF00253068","volume":"18","author":"MP Goren","year":"1986","unstructured":"Goren MP, Wright RK, Horowitz ME. Cumulative renal tubular damage associated with cisplatin nephrotoxicity. Cancer Chemotherapy and Pharmacology 18: 69\u201373, 1986","journal-title":"Cancer Chemotherapy and Pharmacology"},{"key":"BF03259926_CR60","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1001\/archotol.1988.01860230041019","volume":"114","author":"MV Goycoolea","year":"1988","unstructured":"Goycoolea MV, Muchow D, Martinez GC, et al. Permeability of the human round-window membrane to cationic ferritin. Archives of Otolaryngology \u2014Head and Neck Surgery 114: 1247\u20131251, 1988","journal-title":"Archives of Otolaryngology \u2014Head and Neck Surgery"},{"key":"BF03259926_CR61","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0165-5876(80)90004-X","volume":"1","author":"MV Goycoolea","year":"1980","unstructured":"Goycoolea MV, Paparella MM, Goldberg B, et al. Permeability of the middle ear to staphylococcal pyrogenic exotoxin in otitis media. International Journal of Pediatric Otorhinolaryngology 1: 301\u2013308, 1980","journal-title":"International Journal of Pediatric Otorhinolaryngology"},{"key":"BF03259926_CR62","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0022-3565(25)32462-6","volume":"216","author":"TP Green","year":"1981","unstructured":"Green TP, Rybak LP, Mirkin BL, et al. Pharmacologic determinants of ototoxicity of furosemide in the chinchilla. Journal of Pharmacology and Experimental Therapeutics 216: 537\u2013542, 1981","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"BF03259926_CR63","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S0022-3565(25)38916-0","volume":"236","author":"RA Guiliano","year":"1986","unstructured":"Guiliano RA, Verpooten GA, Verbist L, et al. In vivo uptake kinetics of aminoglycosides in the kidney cortex of rats. Journal of Pharmacology and Experimental Therapeutics 236: 470\u2013475, 1986","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"BF03259926_CR64","first-page":"707","volume-title":"Handbook of sensory physiology","author":"JE Hawkins Jr","year":"1976","unstructured":"Hawkins Jr JE. Drug ototoxicity. In Keidel & Neff (Eds) Handbook of sensory physiology, pp. 707\u2013748, Springer, New York, 1976"},{"key":"BF03259926_CR65","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1002\/1097-0142(197704)39:4<1372::AID-CNCR2820390404>3.0.CO;2-J","volume":"39","author":"DM Hayes","year":"1977","unstructured":"Hayes DM, Cvitkovic E, Golbey RB, et al. High dose cis-platinum diammine dichloride: amelioration of renal toxicity by mannitol diuresis. Cancer 39: 1372, 1977","journal-title":"Cancer"},{"key":"BF03259926_CR66","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF00570487","volume":"20","author":"L Heged\u00fcs","year":"1987","unstructured":"Heged\u00fcs L, van der Vijgh WJF, Kelin I, et al. Chemical reactivity of cisplatin bound to human plasma proteins. Cancer Chemotherapy and Pharmacology 20: 211\u2013212, 1987","journal-title":"Cancer Chemotherapy and Pharmacology"},{"key":"BF03259926_CR67","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3109\/15563657808988252","volume":"13","author":"L Helson","year":"1978","unstructured":"Helson L, Okonkwo E, Anton L, Cvitkovic E. Cisplatinum ototoxicity. Clinical Toxicology 13: 469\u2013478, 1978","journal-title":"Clinical Toxicology"},{"key":"BF03259926_CR68","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3109\/00206098809081584","volume":"27","author":"CM Henley III","year":"1988","unstructured":"Henley III CM, Schacht J. Pharmacokinetics of aminoglycoside antibiotics in blood, inner ear fluids and tissues and their relationship to ototoxicity. Audiology 27: 137\u2013146, 1988","journal-title":"Audiology"},{"key":"BF03259926_CR69","first-page":"313","volume":"20","author":"HC Hinshaw","year":"1945","unstructured":"Hinshaw HC, Feldman WH. Streptomycin in the treatment of clinical tuberculosis. Proceedings of the Mayo Clinic 20: 313\u2013318, 1945","journal-title":"Proceedings of the Mayo Clinic"},{"key":"BF03259926_CR70","first-page":"1561","volume":"12","author":"DW Hoffman","year":"1986","unstructured":"Hoffman DW, Whitworth CA, Joyner-Triplett N, Rybak LP. Glutathione depletion markedly enhances drug-induced hearing loss \u2014possible mechanism of ototoxicity. Abstracts of the Society for Neuroscience Meeting 12: 1561, 1986","journal-title":"Abstracts of the Society for Neuroscience Meeting"},{"key":"BF03259926_CR71","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0277-5379(83)90115-3","volume":"19","author":"EE Holdener","year":"1983","unstructured":"Holdener EE, Park CH, Belt RJ, et al. Effect of mannitol and plasma on the cytotoxicity of cis-platin. European Journal of Cancer and Clinical Oncology 19: 515\u2013518, 1983","journal-title":"European Journal of Cancer and Clinical Oncology"},{"key":"BF03259926_CR72","doi-asserted-by":"crossref","unstructured":"Huang M, Schacht J. Outer hair cells as potential targets of inflammatory mediators. Annals of Otology, Rhinology, Laryngology, in press, 1989a","DOI":"10.1177\/00034894900990S610"},{"key":"BF03259926_CR73","unstructured":"Huang M, Schacht J. Isolated cochlear hair cells as an assay for the ototoxicity of drugs. American Academy of Otolaryngology \u2014Head and Neck Surgery Research Forum, New Orleans, abstract, in press, 1989b"},{"key":"BF03259926_CR74","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1172\/JCI111184","volume":"73","author":"HD Humes","year":"1984","unstructured":"Humes HD, Sastrasinh M, Weinberg JM. Calcium is a competitive inhibitor of gentamicin-renal membrane binding interactions and dietary calcium supplementation protects against gentamicin nephrotoxicity. Journal of Clinical Investigation 73: 134\u2013147, 1984","journal-title":"Journal of Clinical Investigation"},{"key":"BF03259926_CR75","first-page":"39","volume":"14","author":"SK Juhn","year":"1981","unstructured":"Juhn SK, Rybak LP, Morizono T, Green TP. Pharmacokinetics of furosemide in relation to the alteration of endocochlear potential. Scandinavian Audiology 14 (Supl.): 39\u201349, 1981","journal-title":"Scandinavian Audiology"},{"key":"BF03259926_CR76","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/BF00258451","volume":"23","author":"AR Khokhar","year":"1989","unstructured":"Khokhar AR, Brown DB, McCormack JJ, Hacker MP. Synthesis and antitumor activity of a series of (aminoethylpyrrolidine) platinum complexes. Cancer Chemotherapy and Pharmacology 23: 15\u201318, 1989","journal-title":"Cancer Chemotherapy and Pharmacology"},{"key":"BF03259926_CR77","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/S0022-3565(25)30017-0","volume":"191","author":"CD Klaassen","year":"1974","unstructured":"Klaassen CD, Fitzgerald TJ. Metabolism and biliary excretion of ethacrynic acid. Journal of Pharmacology and Experimental Therapeutics 191: 548\u2013556, 1974","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"BF03259926_CR78","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1288\/00005537-198808000-00015","volume":"98","author":"S Kohn","year":"1988","unstructured":"Kohn S, Fradis M, Pratt H, et al. Cisplatin ototoxicity in guin\u00e8a pigs with special reference to toxic effects in the stria vascularis. Laryngoscope 98: 865\u2013871, 1988","journal-title":"Laryngoscope"},{"key":"BF03259926_CR79","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1001\/archotol.1981.00790460006003","volume":"107","author":"S Komune","year":"1981","unstructured":"Komune S, Snow JB. Potentiating effects of cisplatin and ethacrynic acid in ototoxicity. Archives of Otolaryngology 107: 594\u2013497, 1981","journal-title":"Archives of Otolaryngology"},{"key":"BF03259926_CR80","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1288\/00005537-198808000-00014","volume":"98","author":"J Kopelman","year":"1988","unstructured":"Kopelman J, Budnick AS, Sessions RB, et al. Ototoxicity of high-dose cisplatin by bolus administration in patients with advanced cancers and normal hearing. Laryngoscopy 98: 858\u2013864, 1988","journal-title":"Laryngoscopy"},{"key":"BF03259926_CR81","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0378-5955(89)90023-3","volume":"37","author":"ABA Kroese","year":"1989","unstructured":"Kroese ABA, Das A, Hudspeth AJ. Blockade of the transduction channels of hair cells in the bullfrog\u2019s sacculus by aminoglycoside antibiotics. Hearing Research 37: 203\u2013218, 1989","journal-title":"Hearing Research"},{"key":"BF03259926_CR82","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0378-5955(82)90053-3","volume":"6","author":"ABA Kroese","year":"1982","unstructured":"Kroese ABA, van den Bercken J. Effects of ototoxic antibiotics on sensory hair cell functioning. Hearing Research 6: 183\u2013197, 1982","journal-title":"Hearing Research"},{"key":"BF03259926_CR83","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0378-5955(89)90125-1","volume":"38","author":"G Laurell","year":"1989","unstructured":"Laurell G, Engstr\u00f6m B. The ototoxic effect of cisplatin on guinea pigs in relation to dosage. Hearing Research 38: 27\u201334, 1989a","journal-title":"Hearing Research"},{"key":"BF03259926_CR84","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0378-5955(89)90124-X","volume":"38","author":"G Laurell","year":"1989","unstructured":"Laurell G, Engstr\u00f6m B. The combined effect of cisplatin and furosemide on hearing function in guinea pigs. Hearing Research 38: 19\u201326, 1989b","journal-title":"Hearing Research"},{"key":"BF03259926_CR85","doi-asserted-by":"crossref","unstructured":"Lazenby CM, Harper ES. Effects of neomycin on K+ transport into inside-out erythrocyte membrane vesicles. Biochemical Society Transactions 625th Meeting, London, p. 598, 1987","DOI":"10.1042\/bst0160598"},{"key":"BF03259926_CR86","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1016\/0006-2952(88)90409-1","volume":"37","author":"CM Lazenby","year":"1988","unstructured":"Lazenby CM, Lee SJ, Harper ES, Gescher A. Glutathione depletion in the guinea pig and its effect on the acute cochlear toxicity of ethacrynic acid. Biochemical Pharmacology 37: 3743\u20133747, 1988","journal-title":"Biochemical Pharmacology"},{"issue":"1","key":"BF03259926_CR87","doi-asserted-by":"crossref","first-page":"S65","DOI":"10.1097\/00005344-198701000-00011","volume":"9","author":"SM Lee","year":"1987","unstructured":"Lee SM, Pattison ME, Michael UF. Nitrendipine protects against aminoglycoside nephrotoxicity in the rat. Journal of Cardiovascular Pharmacology 9 (Suppl. 1): S65\u2013S69, 1987","journal-title":"Journal of Cardiovascular Pharmacology"},{"key":"BF03259926_CR88","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0378-5955(87)90112-2","volume":"26","author":"M Lenoir","year":"1987","unstructured":"Lenoir M, Puel J-L. Dose-dependent changes in the rat cochlea following aminoglycoside intoxication. II. Histological study. Hearing Research 26: 199\u2013209, 1987","journal-title":"Hearing Research"},{"key":"BF03259926_CR89","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/S0140-6736(83)92864-7","volume":"1","author":"AM Lerner","year":"1983","unstructured":"Lerner AM, Reyes MP, Cone LA, et al. Randomized, controlled trial of the comparative efficacy, auditory toxicity, and nephrotoxicity of tobramycin and netilmicin. Lancet 1: 1123\u20131126, 1983","journal-title":"Lancet"},{"key":"BF03259926_CR90","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1177\/019459987908700218","volume":"87","author":"SA Lerner","year":"1979","unstructured":"Lerner SA, Matz GJ. Suggestion for monitoring patients during treatment with aminoglycoside antibiotics. Otolaryngology \u2014Head and Neck Surgery 87: 222\u2013228, 1979","journal-title":"Otolaryngology \u2014Head and Neck Surgery"},{"key":"BF03259926_CR91","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3109\/01050398609045952","volume":"15","author":"G Levin","year":"1986","unstructured":"Levin G, Behrenth E. Irreversible ototoxic effect of erythromycin. Scandinavian Audiology 15: 41\u201342, 1986","journal-title":"Scandinavian Audiology"},{"key":"BF03259926_CR92","first-page":"63","volume":"7","author":"CJL Lock","year":"1977","unstructured":"Lock CJL, Bradford J, Faggiani R, et al. The structure of platinum anticancer agents and their metabolites. Journal of Clinical Hematology and Oncology 7: 63\u201378, 1977","journal-title":"Journal of Clinical Hematology and Oncology"},{"key":"BF03259926_CR93","first-page":"131","volume":"14","author":"SC Marks","year":"1981","unstructured":"Marks SC, Schacht J. Effects of ototoxic diuretics on cochlear Na+-K+-ATPase and adenylate cyclase. Scandinavian Audiology 14 (Suppl.): 131\u2013137, 1981","journal-title":"Scandinavian Audiology"},{"key":"BF03259926_CR94","doi-asserted-by":"crossref","first-page":"S60","DOI":"10.1121\/1.1995333","volume":"57","author":"DM Marques","year":"1975","unstructured":"Marques DM, Clark CS, Hawkins Jr JE. Potentiation of cochlear injury by noise and ototoxic antibiotics in guinea pigs. Journal of the Acoustical Society of America 57 (Suppl.): S60, 1975","journal-title":"Journal of the Acoustical Society of America"},{"key":"BF03259926_CR95","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1056\/NEJM196905292802208","volume":"280","author":"RH Mathog","year":"1969","unstructured":"Mathog RH, Klein Jr WJ. Ototoxicity of ethacrynic acid and aminoglycoside antibiotics in uremia. New England Journal of Medicine 280: 1223\u20131224, 1969","journal-title":"New England Journal of Medicine"},{"key":"BF03259926_CR96","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1288\/00005537-197608000-00001","volume":"86","author":"GJ Matz","year":"1976","unstructured":"Matz GJ. The ototoxic effects of ethacrynic acid in man and animals. Laryngoscope 86: 1065\u20131086, 1976","journal-title":"Laryngoscope"},{"key":"BF03259926_CR97","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1001\/archotol.1969.00770030154011","volume":"90","author":"GJ Matz","year":"1969","unstructured":"Matz GJ, Beal DD, Krames L. Ototoxicity of ethacrynic acid demonstrated in a human temporal bone. Archives of Otolaryngology 90: 152\u2013159, 1969","journal-title":"Archives of Otolaryngology"},{"key":"BF03259926_CR98","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1177\/000348946507400203","volume":"74","author":"PA McCabe","year":"1965","unstructured":"McCabe PA, Dey FL. The effect of aspirin upon auditory sensitivity. Annals of Otology, Rhinology, Laryngology 74: 312\u2013325, 1965","journal-title":"Annals of Otology, Rhinology, Laryngology"},{"key":"BF03259926_CR99","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0378-5955(83)90033-3","volume":"9","author":"D McFadden","year":"1983","unstructured":"McFadden D, Plattsmier HS. Aspirin can potentiate the temporary hearing loss induced by intense sounds. Hearing Research 9: 295\u2013316, 1983","journal-title":"Hearing Research"},{"key":"BF03259926_CR100","first-page":"267","volume":"10","author":"JE McGinness","year":"1978","unstructured":"McGinness JE, Procter PH, Demopoulos HB, et al. Amelioration of cis-platinum nephrotoxicity by orgotein (superoxide dismutase). Physiological Chemistry and Physics 10: 267\u2013277, 1978","journal-title":"Physiological Chemistry and Physics"},{"key":"BF03259926_CR101","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/1097-0142(19850101)55:1<41::AID-CNCR2820550106>3.0.CO;2-N","volume":"55","author":"LB Melamed","year":"1985","unstructured":"Melamed LB, Selim MA, Schuchman D. Cisplatin ototoxicity in gynecologic cancer patients. Cancer 55: 41\u201343, 1985","journal-title":"Cancer"},{"key":"BF03259926_CR102","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0378-5955(78)90007-2","volume":"1","author":"I Melichar","year":"1978","unstructured":"Melichar I, Syka J. The effects of ethacrynic acid upon the potassium concentration in guinea pig inner ear fluids. Hearing Research 1: 35\u201341, 1978","journal-title":"Hearing Research"},{"key":"BF03259926_CR103","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1001\/archotol.1973.00780020309003","volume":"98","author":"C Mitchell","year":"1973","unstructured":"Mitchell C, Brummett R, Himes D, Vernon J. Electrophysiological study of the effect of sodium salicylate upon the cochlea. Archives of Otolaryngology 98: 297\u2013301, 1973","journal-title":"Archives of Otolaryngology"},{"key":"BF03259926_CR104","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0022-3565(25)30654-3","volume":"199","author":"JR Mitchell","year":"1976","unstructured":"Mitchell JR, Nelson WL, Potter WE, et al. Metabolic activation of furosemide to a chemically reactive, hepatotoxic metabolite. Journal of Pharmacology and Experimental Therapeutics 199: 41\u201352, 1976","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"BF03259926_CR105","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/infdis\/149.1.23","volume":"149","author":"RD Moore","year":"1984","unstructured":"Moore RD, Smith CR, Leitman PS. Risk factors for the development of auditory toxicity in patients receiving aminoglycosides. Journal of Infectious Disease 149: 23\u201330, 1984b","journal-title":"Journal of Infectious Disease"},{"key":"BF03259926_CR106","doi-asserted-by":"crossref","first-page":"352","DOI":"10.7326\/0003-4819-100-3-352","volume":"100","author":"RD Moore","year":"1984","unstructured":"Moore RD, Smith CR, Lipsky JJ, et al. Risk factors for nephrotoxicity in patients treated with aminoglycosides. Annals of Internal Medicine 100: 352\u2013357, 1984a","journal-title":"Annals of Internal Medicine"},{"key":"BF03259926_CR107","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0196-0709(80)80020-2","volume":"1","author":"T Morizono","year":"1980","unstructured":"Morizono T, Paparella MM, Juhn SK. Ototoxicity of propylene glycol in experimental animals. American Journal of Otolaryngology 1: 393\u2013399, 1980","journal-title":"American Journal of Otolaryngology"},{"key":"BF03259926_CR108","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1001\/archotol.1965.00760010485006","volume":"82","author":"EN Myers","year":"1965","unstructured":"Myers EN, Bernstein JM. Salicylate ototoxicity. Archives of Otolaryngology 82: 483\u2013493, 1965","journal-title":"Archives of Otolaryngology"},{"key":"BF03259926_CR109","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1136\/bmj.1.5906.477","volume":"1","author":"P Noone","year":"1974","unstructured":"Noone P, Parsons TMC, Pattison JR, et al. Experience in monitoring gentamicin therapy treatment of serious gram-negative sepsis. British Journal of Medicine 1: 477\u2013481, 1974","journal-title":"British Journal of Medicine"},{"key":"BF03259926_CR110","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0378-5955(87)90160-2","volume":"29","author":"FF Offner","year":"1987","unstructured":"Offner FF, Dallos P, Cheatham MA. Positive endocochlear potential: mechanism of production by marginal cells of the stria vascularis. Hearing Research 29: 117\u2013124, 1987","journal-title":"Hearing Research"},{"key":"BF03259926_CR111","unstructured":"Ohlsen AK, Nuttall AL, Miller JM. The influence of adrenergic drugs on the cochlear blood flow. Association for Research in Otolaryngology 12th Midwinter Meeting, St Petersburg Beach, Florida, February 5\u20139, 1989. Abstract no. 116, p. 103, 1989"},{"key":"BF03259926_CR112","first-page":"290","volume":"15","author":"I Ohtani","year":"1984","unstructured":"Ohtani I, Ohtsuki K, Aikawa T, et al. Protective effect of fosfomycin against cisplatin-induced ototoxicity in rats. Ear Research Japan 15: 290\u2013292, 1984","journal-title":"Ear Research Japan"},{"key":"BF03259926_CR113","first-page":"42","volume":"47","author":"I Ohtani","year":"1985","unstructured":"Ohtani I, Ohtsuki K, Aikawa T, et al. Protective effect of fosfo-mycin against aminoglycoside ototoxicity. Otology-Rhinology-Laryngology 47: 42\u201348, 1985","journal-title":"Otology-Rhinology-Laryngology"},{"key":"BF03259926_CR114","first-page":"85","volume":"13","author":"K Ohtsuki","year":"1982","unstructured":"Ohtsuki K, Ohtani I, Aikawa T, et al. The ototoxicity and the accumulation in the inner ear of the various aminoglycoside antibiotics. Ear Research Japan 13: 85\u201387, 1982","journal-title":"Ear Research Japan"},{"key":"BF03259926_CR115","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3109\/00016488209130850","volume":"93","author":"A Orsulakova","year":"1981","unstructured":"Orsulakova A, Schacht J. A biochemical mechanism of the ototoxic interaction between neomycin and ethacrynic acid. Acta Oto-laryngologica 93: 43\u201348, 1981","journal-title":"Acta Oto-laryngologica"},{"key":"BF03259926_CR116","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-5955(88)90042-1","volume":"35","author":"WC Otto","year":"1988","unstructured":"Otto WC, Brown RD, Gage-White L, et al. Effects of cisplatin and thiosulfate upon auditory brainstem responses of guinea pigs. Hearing Research 35: 79\u201386, 1988","journal-title":"Hearing Research"},{"key":"BF03259926_CR117","first-page":"218","volume":"31","author":"J Ouchi","year":"1969","unstructured":"Ouchi J, Ohtani I. Studies on the otoxicity of kanamycin (the correlation between electrophysiological findings and histopathological changes). Practice Oto-Rhino-Laryngologica 31: 218\u2013233, 1969","journal-title":"Practice Oto-Rhino-Laryngologica"},{"key":"BF03259926_CR118","first-page":"537","volume":"9","author":"L Palmieri","year":"1983","unstructured":"Palmieri L, Cioni L, Puccini R, Schnoblinova Z. A study on reduced gentamicin nephrotoxicity and increased antibacterial action by a gentamicin-fosfomycin association in vitro and vivo. Drugs and Experimental Clinical Research 9: 537\u2013543, 1983","journal-title":"Drugs and Experimental Clinical Research"},{"key":"BF03259926_CR119","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0041-008X(82)90004-7","volume":"65","author":"L Parravicini","year":"1982","unstructured":"Parravicini L, Arpini A, Bamonte F, et al. Comparative ototoxicity of amikacin, gentamicin, netilmicin, and tobramycin in guinea pigs. Toxicology and Applied Pharmacology 65: 222\u2013230, 1982","journal-title":"Toxicology and Applied Pharmacology"},{"key":"BF03259926_CR120","first-page":"871","volume":"58","author":"I Piel","year":"1974","unstructured":"Piel I, Myer D, Perlia C, Wolfe V. Effects of cis-diamminedichloroplatinum (NSC-119875) on hearing function in man. Cancer Chemotherapy Reports 58: 871\u2013875, 1974","journal-title":"Cancer Chemotherapy Reports"},{"key":"BF03259926_CR121","first-page":"103","volume":"8","author":"GT Pryor","year":"1986","unstructured":"Pryor GT, Howd RA. Toluene-induced ototoxicity by subcutaneous administration. Neurobiology and Toxicology 8: 103\u2013104, 1986","journal-title":"Neurobiology and Toxicology"},{"key":"BF03259926_CR122","first-page":"223","volume":"6","author":"GT Pryor","year":"1984","unstructured":"Pryor GT, Rebert CS, Dickinson J, Feeney EM. Factors affecting toluene-induced ototoxicity in rats. Neurobiology and Toxicology 6: 223\u2013238, 1984","journal-title":"Neurobiology and Toxicology"},{"key":"BF03259926_CR123","first-page":"94","volume":"84","author":"CA Quick","year":"1975","unstructured":"Quick CA, Hoppe W. Permanent deafness associated with furosemide administration. Annals of Otology 84: 94\u2013101, 1975","journal-title":"Annals of Otology"},{"key":"BF03259926_CR124","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0378-5955(89)90133-0","volume":"38","author":"WS Quirk","year":"1989","unstructured":"Quirk WS, Dengerink HA, Harding JW, et al. Autoregulation of cochlear blood flow in normotensive and spontaneously hypertensive rats following intracerebroventricularly mediated adjustment of blood pressure. Hearing Research 38: 119\u2013124, 1989a","journal-title":"Hearing Research"},{"key":"BF03259926_CR125","unstructured":"Quirk WS, Wright JW, Coleman JK, Dengerink HA. Autoregulation of cochlear blood flow in Wistar-Kyoto rats. Association for Research in Otolaryngology 12th Midwinter Meeting, St Petersburg Beach, Florida, February 5\u20139, 1989. Abstract no. 115, p. 103, 1989b"},{"key":"BF03259926_CR126","first-page":"199","volume":"10","author":"LJ Rankin","year":"1984","unstructured":"Rankin LJ, Krous H, Fryer AW, Whang R. Enhancement of gentamicin nephrotoxicity by magnesium depletion. Mineral and Electrolyte Metabolism 10: 199\u2013203, 1984","journal-title":"Mineral and Electrolyte Metabolism"},{"key":"BF03259926_CR127","first-page":"F83","volume":"240","author":"BR Rennick","year":"1981","unstructured":"Rennick BR. Renal tubule transport of organic cations. American Journal of Physiology 240: F83\u2013F89, 1981","journal-title":"American Journal of Physiology"},{"key":"BF03259926_CR128","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/00007611-197801000-00029","volume":"71","author":"SI Rifkin","year":"1978","unstructured":"Rifkin SI, De Quesada AM, Pickering MJ, Shires Jr DL. Deafness associated with oral furosemide. Southern Medical Journal 71: 86\u201388, 1978","journal-title":"Southern Medical Journal"},{"key":"BF03259926_CR129","first-page":"781","volume":"63","author":"DA Ross","year":"1979","unstructured":"Ross DA, Gayle GR. Reduction of the renal toxicity of cisdichlorodiammineplatinum (II) by probenecid. Cancer Treatment Reports 63: 781\u2013787, 1979","journal-title":"Cancer Treatment Reports"},{"key":"BF03259926_CR130","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1017\/S0022215100105523","volume":"102","author":"LP Rybak","year":"1988","unstructured":"Rybak LP. Ototoxicity of ethacrynic acid (a persistent clinical problem). Journal of Laryngology and Otology 102: 518\u2013520, 1988","journal-title":"Journal of Laryngology and Otology"},{"key":"BF03259926_CR131","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0378-5955(87)90037-2","volume":"26","author":"LP Rybak","year":"1987","unstructured":"Rybak LP, Whitworth C. Some organic acids attenuate the effects of furosemide on the endocochlear potential. Hearing Research 26: 89\u201393, 1987","journal-title":"Hearing Research"},{"key":"BF03259926_CR132","unstructured":"Rybak LP, Whitworth C. Effects of organic acids on the edema of the stria vascularis induced by furosemide. Association for Research in Otolaryngology 11th Midwinter Meeting, Clearwater Beach, Florida, January 31\u2013February 4, 1988. Abstract no. 143, p. 116, 1988"},{"key":"BF03259926_CR133","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/ki.1984.86","volume":"25","author":"R Safirstein","year":"1984","unstructured":"Safirstein R, Miller P, Guttenplan JB. Uptake and metabolism of cis-platinum by rat kidney. Kidney International 25: 753\u2013758, 1984","journal-title":"Kidney International"},{"key":"BF03259926_CR134","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1288\/00005537-198708000-00020","volume":"97","author":"AN Salt","year":"1987","unstructured":"Salt AN, Melichar I, Thalmann R. Mechanisms of endocochlear potential generation by stria vascularis. Laryngoscope 97: 984\u2013991, 1987","journal-title":"Laryngoscope"},{"key":"BF03259926_CR135","unstructured":"Salvi RI, Kamen BA. Interaction of noise and cisplatinum. Association for Research in Otolaryngology 11th Midwinter Meeting, Clearwater Beach, Florida, January 31\u2013February 4, 1988. Abstract no. 81, p. 68, 1988"},{"key":"BF03259926_CR136","doi-asserted-by":"crossref","first-page":"94","DOI":"10.5271\/sjweh.2628","volume":"6","author":"K Savolainen","year":"1980","unstructured":"Savolainen K, Riihimaki V, Vaheri E, Linnoila M. Effects of xylene and alcohol on vestibular and visual functions in man. Scandinavian Journal of Work Environment and Health 6: 94\u2013103, 1980","journal-title":"Scandinavian Journal of Work Environment and Health"},{"key":"BF03259926_CR137","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1093\/infdis\/153.6.1062","volume":"153","author":"CL Sawyers","year":"1986","unstructured":"Sawyers CL, Moore RD, Lerner SA, et al. A model for predicting nephrotoxicity in patients treated with aminoglycosides. Journal of Infectious Disease 153: 1062\u20131068, 1986","journal-title":"Journal of Infectious Disease"},{"key":"BF03259926_CR138","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00455236","volume":"224","author":"J Schacht","year":"1979","unstructured":"Schacht J. Isolation of an aminoglycoside receptor from guinea pig inner ear tissues and kidneys. Archives of Otorhinolaryngology 224: 129\u2013134, 1979","journal-title":"Archives of Otorhinolaryngology"},{"key":"BF03259926_CR139","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0378-5955(86)90105-X","volume":"22","author":"J Schacht","year":"1986","unstructured":"Schacht J. Molecular mechanism of drug-induced hearing loss. Hearing Research 22: 297\u2013304, 1986","journal-title":"Hearing Research"},{"key":"BF03259926_CR140","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/978-1-4684-3279-4_9","volume":"89","author":"J Schacht","year":"1977","unstructured":"Schacht J, Lodhi S, Weiner ND. Effects of neomycin on polyphosphoinositides in inner ear tissues and monomolecular films. Advances in Experimental Medical Biology 89: 191\u2013208, 1977","journal-title":"Advances in Experimental Medical Biology"},{"key":"BF03259926_CR141","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1002\/1097-0142(19851015)56:8<1934::AID-CNCR2820560807>3.0.CO;2-F","volume":"56","author":"SD Schaefer","year":"1985","unstructured":"Schaefer SD, Post JD, Close LG, Wright CG. Ototoxicity of low- and moderate-dose cisplatin. Cancer 56: 1934\u20131939, 1985","journal-title":"Cancer"},{"key":"BF03259926_CR142","first-page":"1","volume":"132","author":"HF Schuknecht","year":"1957","unstructured":"Schuknecht HF. Ablation therapy in the management of M\u00e9niere\u2019s disease. Acta Oto-Laryngologica 132: 1\u201342, 1957","journal-title":"Acta Oto-Laryngologica"},{"key":"BF03259926_CR143","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1056\/NEJM197006182822506","volume":"282","author":"GH Schwartz","year":"1970","unstructured":"Schwartz GH, David DS, Riggio RR, et al. Ototoxicity induced by furosemide. New England Journal of Medicine 282: 1413\u20131414, 1970","journal-title":"New England Journal of Medicine"},{"key":"BF03259926_CR144","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1288\/00005537-198609000-00005","volume":"96","author":"VG Schweitzer","year":"1986","unstructured":"Schweitzer VG, Dolan DF, Abrams GE, et al. Amelioration of cisplatin-induced ototoxicity by fosfomycin. Laryngoscope 96: 948\u2013958, 1986","journal-title":"Laryngoscope"},{"key":"BF03259926_CR145","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1177\/019459988409200109","volume":"92","author":"VG Schweitzer","year":"1984","unstructured":"Schweitzer VG, Hawkins JE, Lilly DJ, et al. Ototoxic and nephrotoxic effects of combined treatment with cis-diamminedichloroplatinum and kanamycin in the guinea pig. Otolaryngology \u2014Head and Neck Surgery 92: 38\u201349, 1984","journal-title":"Otolaryngology \u2014Head and Neck Surgery"},{"key":"BF03259926_CR146","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1177\/019459988609400410","volume":"94","author":"VG Schweitzer","year":"1986","unstructured":"Schweitzer VG, Rarey KE, Dolan DF, et al. Ototoxicity of cisplatin vs platinum analogs CBDCA (JM-8) and CHIP (JM-9). Otolaryngology \u2014Head and Neck Surgery 94: 458\u2013470, 1986","journal-title":"Otolaryngology \u2014Head and Neck Surgery"},{"key":"BF03259926_CR147","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0022-3565(25)38814-2","volume":"236","author":"DW Schwertz","year":"1986","unstructured":"Schwertz DW, Kreisberg JI, Venkatachalam MA. Gentamicin-induced alterations in pig kidney epithelial (LLC-PK1) cell in culture. Journal of Pharmacology and Experimental Therapeutics 236: 254\u2013262, 1986","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"BF03259926_CR148","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1177\/000348946707600109","volume":"76","author":"H Silverstein","year":"1967","unstructured":"Silverstein H, Bernstein JM, Davies DG. Salicylate ototoxicity: a biochemical and electrophysiological study. Annals of Otology, Rhinology and Laryngology 76: 118\u2013128, 1967","journal-title":"Annals of Otology, Rhinology and Laryngology"},{"key":"BF03259926_CR149","first-page":"261","volume":"58","author":"R Skinner","year":"1988","unstructured":"Skinner R, Pearson ADJ, Amineddine HA, et al. Ototoxicity of cisplatinum. British Journal of Cancer 58: 261, 1988","journal-title":"British Journal of Cancer"},{"key":"BF03259926_CR150","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1152\/ajplegacy.1958.193.1.203","volume":"193","author":"CA Smith","year":"1958","unstructured":"Smith CA, Davis H, Deatherage BH, Gessert CF. DC potentials of the membranous labyrinth. American Journal of Physiology 193: 203\u2013206, 1958","journal-title":"American Journal of Physiology"},{"key":"BF03259926_CR151","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1056\/NEJM198005153022002","volume":"302","author":"CR Smith","year":"1980","unstructured":"Smith CR, Lipsky JJ, Laskin OL, et al. Double-blind comparison of nephrotoxicity and auditory toxicity of gentamicin and tobramycin. New England Journal of Medicine 302: 1106\u20131109, 1980","journal-title":"New England Journal of Medicine"},{"key":"BF03259926_CR152","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3109\/00206097309071650","volume":"12","author":"H Stupp","year":"1973","unstructured":"Stupp H, Kupper K, Lagler F, Sous H, Quante M. Inner ear concentrations and ototoxicity of different antibiotics in local and systemic application. Audiology 12: 350\u2013363, 1973","journal-title":"Audiology"},{"key":"BF03259926_CR153","unstructured":"Stypulkowski PH. The mechanism(s) of salicylate (aspirin) induced hearing loss and tinnitus. Association for Research in Otolaryngology 12th Midwinter Meeting, St Petersburg Beach, Florida, February 5\u20139, 1989. Abstract no. 225, p. 189, 1989"},{"key":"BF03259926_CR154","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0892-0362(88)90088-8","volume":"10","author":"M Sullivan","year":"1988","unstructured":"Sullivan M, Rarey K, Conolly R. Ototoxicity of toluene in rats. Neurotoxicology and Teratology 10: 525\u2013530, 1988","journal-title":"Neurotoxicology and Teratology"},{"key":"BF03259926_CR155","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0041-008X(80)90233-1","volume":"55","author":"RJ Szot","year":"1980","unstructured":"Szot RJ, McCormick M, Chung B, et al. Comparative toxicity of netilmicin and tobramycin in dogs. Toxicology and Applied Pharmacology 55: 169\u2013178, 1980","journal-title":"Toxicology and Applied Pharmacology"},{"key":"BF03259926_CR156","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3109\/00016488309132872","volume":"96","author":"M Tachibana","year":"1983","unstructured":"Tachibana M, Anniko M, Schacht J. Effects of perilymphatically perfused gentamicin on microphonic potential, lipid labelling and morphology of cochlear tissues. Acta Oto-Laryngologica 96: 31\u201338, 1983","journal-title":"Acta Oto-Laryngologica"},{"key":"BF03259926_CR157","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0378-5955(85)90144-3","volume":"19","author":"A Takada","year":"1985","unstructured":"Takada A, Bledsoe Jr S, Schacht J. An energy-dependent step in aminoglycoside ototoxicity: prevention of gentamicin ototoxicity during reduced endolymphatic potential. Hearing Research 19: 245\u2013251, 1985","journal-title":"Hearing Research"},{"key":"BF03259926_CR158","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0378-5955(82)90073-9","volume":"8","author":"A Takada","year":"1982","unstructured":"Takada A, Schacht J. Calcium antagonism and reversibility of gentamicin-induced loss of cochlear microphonics in the guinea pig. Hearing Research 8: 179\u2013186, 1982","journal-title":"Hearing Research"},{"key":"BF03259926_CR159","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/BF00454130","volume":"246","author":"M Takumida","year":"1989","unstructured":"Takumida M, Wers\u00e4ll J, Bagger-Sj\u00f6b\u00e4ck D. Initial changes in the sensory hair-cell membrane following aminoglycoside administration in a guinea pig model. Archives of Otorhinolaryngology 246: 26\u201331, 1989","journal-title":"Archives of Otorhinolaryngology"},{"key":"BF03259926_CR160","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/BF00453712","volume":"237","author":"RA Tange","year":"1982","unstructured":"Tange RA, Conjin EAJG, van Zeijl LPGM. The cortitoxic effects of cis-platinum in the guinea pig. Archives of Otorhinolaryngology 237: 17\u201326, 1982","journal-title":"Archives of Otorhinolaryngology"},{"key":"BF03259926_CR161","doi-asserted-by":"crossref","unstructured":"Tange RA, Vuzcvski VD. Changes in the stria vascularis of the guinea pig due to cis-platinum. Archives of Otorhinolaryngology 41\u201347, 1983","DOI":"10.1007\/BF00454261"},{"key":"BF03259926_CR162","first-page":"2538","volume":"48","author":"LK Tay","year":"1988","unstructured":"Tay LK, Bregman CL, Masters BA, Williams PD. Effects of cisdiammino-dichloroplatinum (II) on rabbit kidney in vivo and on rabbit renal proximal cells in culture. Cancer Research 48: 2538\u20132543, 1988","journal-title":"Cancer Research"},{"key":"BF03259926_CR163","doi-asserted-by":"crossref","first-page":"421","DOI":"10.3109\/00016488209128930","volume":"94","author":"O Tjernstr\u00f6m","year":"1982","unstructured":"Tjernstr\u00f6m O, Denneberg T, Harris S, et al. Ototoxicity of netilmicin. Acta Oto-Laryngologica 94: 421\u2013429, 1982","journal-title":"Acta Oto-Laryngologica"},{"key":"BF03259926_CR164","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1172\/JCI112463","volume":"77","author":"P Tran Ba Huy","year":"1986","unstructured":"Tran Ba Huy P, Bernard P, Schacht J. Kinetics of gentamicin uptake and release in the rat: comparison of inner ear tissues and fluids with other organs. Journal of Clinical Investigation 77: 1492\u20131500, 1986","journal-title":"Journal of Clinical Investigation"},{"key":"BF03259926_CR165","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0378-5955(83)90078-3","volume":"11","author":"P Tran Ba Huy","year":"1983","unstructured":"Tran Ba Huy P, Manuel C, Meulemans A, et al. Ethacrynic acid facilitates gentamicin entry into endolymph of the rat. Hearing Research 11: 191\u2013202, 1983","journal-title":"Hearing Research"},{"key":"BF03259926_CR166","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/00000441-198801000-00003","volume":"295","author":"S Umeki","year":"1988","unstructured":"Umeki S, Watanabe M, Yagi S, Soejima R. Supplemental fosfomycin and\/or steroids that reduce cisplatin-induced nephrotoxicity. American Journal of Medical Science 295: 6\u201310, 1988","journal-title":"American Journal of Medical Science"},{"key":"BF03259926_CR167","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/hep.1840090402","volume":"9","author":"N Vakil","year":"1989","unstructured":"Vakil N, Abu-Alfa A, Mujais SK. Gentamicin nephrotoxicity in extrahepatic cholestasis: modulation by dietary calcium. Hepatology 9: 519\u2013524, 1989","journal-title":"Hepatology"},{"key":"BF03259926_CR168","first-page":"407","volume":"84","author":"J Vernon","year":"1977","unstructured":"Vernon J, Brummett RE. Noise trauma in the presence of loop-inhibiting diuretics. Transactions of the American Academy of Ophthalmology and Otolaryngology 84: 407\u2013413, 1977","journal-title":"Transactions of the American Academy of Ophthalmology and Otolaryngology"},{"key":"BF03259926_CR169","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/clpt.1989.4","volume":"45","author":"GA Verpooten","year":"1989","unstructured":"Verpooten GA, Guiliano RA, Verbist L, et al. Once-daily dosing decreases renal accumulation of gentamicin and netilmicin. Clinical Pharmacology and Therapeutics 45: 22\u201327, 1989","journal-title":"Clinical Pharmacology and Therapeutics"},{"key":"BF03259926_CR170","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1121\/1.1906851","volume":"24","author":"G B\u00e9k\u00e9sy Von","year":"1952","unstructured":"Von B\u00e9k\u00e9sy G. DC resting potentials inside the cochlear partition. Journal of the Acoustical Society of America 24: 72\u201376, 1952","journal-title":"Journal of the Acoustical Society of America"},{"key":"BF03259926_CR171","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/BF00391499","volume":"114","author":"T Wagner","year":"1988","unstructured":"Wagner T, Kreft B, Bohlmann G, Schwieder G. Effects of fosfomycin, mesna, and sodium thiosulfate on the toxicity and antitumor activity of cisplatin. Journal of Cancer Research and Clinical Oncology 114: 497, 1988","journal-title":"Journal of Cancer Research and Clinical Oncology"},{"key":"BF03259926_CR172","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1126\/science.118.3062.259","volume":"118","author":"SA Waksman","year":"1953","unstructured":"Waksman SA. Streptomycin: background, isolation, properties and utilization. Science 118: 259\u2013266, 1953","journal-title":"Science"},{"key":"BF03259926_CR173","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0022-3565(25)31249-8","volume":"205","author":"JD Wallin","year":"1978","unstructured":"Wallin JD, Clifton G, Kaplowitz N. The effect of phenobarbital, probenecid and diethyl maleate on the pharmacokinetics and biliary excretion of ethacrynic acid in the rat. Journal of Pharmacology and Experimental Therapeutics 205: 471, 1978","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"BF03259926_CR174","doi-asserted-by":"crossref","first-page":"3257","DOI":"10.1016\/0006-2952(84)90087-X","volume":"33","author":"MB Wang","year":"1984","unstructured":"Wang MB, Weiner ND, Takada A, Schacht J. Characterization of aminoglycoside-lipid interactions and development of a refined model for ototoxicity testing. Biochemical Pharmacology 33: 3257\u20133262, 1984","journal-title":"Biochemical Pharmacology"},{"key":"BF03259926_CR175","first-page":"1238","volume":"37","author":"JM Ward","year":"1977","unstructured":"Ward JM, Grabin ME, Berlin E, Young DM. Prevention of renal failure in rats receiving cis-diamminedichloroplatinum (II) by administration of furosemide. Cancer Research 37: 1238\u20131240, 1977","journal-title":"Cancer Research"},{"key":"BF03259926_CR176","first-page":"104","volume":"23","author":"J Wers\u00e4ll","year":"1980","unstructured":"Wers\u00e4ll J. The ototoxic potential of netilmicin compared with amikacin: an animal study in guinea pigs. Scandinavian Journal of Infectious Disease 23 (Suppol.): 104\u2013113, 1980","journal-title":"Scandinavian Journal of Infectious Disease"},{"key":"BF03259926_CR177","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/0024-3205(64)90132-8","volume":"3","author":"J Wers\u00e4ll","year":"1964","unstructured":"Wers\u00e4ll J, Flock \u00c5. Suppression and restoration of the microphonic output from the lateral line organ after local application of streptomycin. Life Science 3: 1151\u20131155, 1964","journal-title":"Life Science"},{"key":"BF03259926_CR178","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1001\/archotol.1973.00780020036009","volume":"98","author":"BA West","year":"1973","unstructured":"West BA, Brummett RE, Hirnes DL. Interaction of kanamycin and ethacrynic acid. Archives of Otolaryngology 98: 32\u201337, 1973","journal-title":"Archives of Otolaryngology"},{"key":"BF03259926_CR179","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0378-5955(87)90177-8","volume":"30","author":"SE Williams","year":"1987","unstructured":"Williams SE, Zenner HP, Schacht J. Three molecular steps of aminoglycoside ototoxicity demonstrated in outer hair cells. Hearing Research 30: 11\u201318, 1987","journal-title":"Hearing Research"},{"key":"BF03259926_CR180","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1159\/000185248","volume":"51","author":"NLM Wong","year":"1989","unstructured":"Wong NLM, Magil AB, Dirks JH. Effect of magnesium diet in gentamicin-induced acute renal failure in rats. Nephron 51: 84\u201388, 1989","journal-title":"Nephron"},{"key":"BF03259926_CR181","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1288\/00005537-198212000-00013","volume":"92","author":"CG Wright","year":"1982","unstructured":"Wright CG, Schaefer SD. Inner ear histopathology in patients treated with cis-platinum. Laryngoscope 92: 1408\u20131413, 1982","journal-title":"Laryngoscope"},{"key":"BF03259926_CR182","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3109\/00016488809102854","volume":"447","author":"H Yamane","year":"1988","unstructured":"Yamane H, Nakai Y, Konishi K. Furosemide-induced alteration of drug pathway to cochlea. Acta Oto-Laryngologica (Suppl.) 447: 28\u201335, 1988","journal-title":"Acta Oto-Laryngologica (Suppl.)"},{"key":"BF03259926_CR183","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0041-008X(86)90441-2","volume":"82","author":"JS Young","year":"1986","unstructured":"Young JS, Fechter LD. Trimethyltin exposure produces an unusual form of toxic auditory damage in rats. Toxicology and Applied Pharmacology 82: 87\u201393, 1986","journal-title":"Toxicology and Applied Pharmacology"},{"key":"BF03259926_CR184","first-page":"57","volume":"64","author":"JM Yuhas","year":"1980","unstructured":"Yuhas JM, Culo F. Selective inhibition of the nephrotoxicity of cis-dichlorodiammine platinum (II) by WR-27-21 without altering its anti-tumor properties. Cancer Treatment Reports 64: 57\u201364, 1980","journal-title":"Cancer Treatment Reports"}],"container-title":["Medical Toxicology and Adverse Drug Experience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03259926.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03259926\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03259926","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T23:10:48Z","timestamp":1745363448000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03259926"}},"subtitle":["Pathogenesis and Prevention"],"short-title":[],"issued":{"date-parts":[[1989,12]]},"references-count":184,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1989,12]]}},"alternative-id":["BF03259926"],"URL":"https:\/\/doi.org\/10.1007\/bf03259926","relation":{},"ISSN":["0113-5244","1179-1942"],"issn-type":[{"value":"0113-5244","type":"print"},{"value":"1179-1942","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,12]]}}}