{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:06:26Z","timestamp":1791947186971,"version":"4.3.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[2000,4]]},"DOI":"10.1007\/bf03343713","type":"journal-article","created":{"date-parts":[[2014,3,11]],"date-time":"2014-03-11T05:10:51Z","timestamp":1394514651000},"page":"231-234","source":"Crossref","is-referenced-by-count":75,"title":["Activin A stimulates insulin secretion in cultured human pancreatic islets"],"prefix":"10.1007","volume":"23","author":[{"given":"P.","family":"Florio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Luisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Marchetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Lupi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Cobellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Falaschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Sugino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Navalesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. R.","family":"Genazzani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Petraglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,3,11]]},"reference":[{"key":"BF03343713_CR1","first-page":"1","volume":"44","author":"W Vale","year":"1988","unstructured":"Vale W., Rivier C., Hsueh A., Campen C., Meunier H., Bicsak T., Vaughan J., Corrigan A., Bardin W., Sawchenko P., Petraglia F., Plotsky P., Spiess J., Rivier J. Chemical and biological characterization of the inhibin family of protein hormones. Rec. Progr. Horm. Res. 1988, 44: 1\u201334.","journal-title":"Rec. Progr. Horm. Res."},{"key":"BF03343713_CR2","first-page":"156","volume":"17","author":"F Petraglia","year":"1996","unstructured":"Petraglia F., Florio P., Nappi C., Genazzani A.R. Peptide signalling in human placenta and fetal membranes: autocrine, paracrine, and endocrine mechanisms. Endocr. Rev. 1996, 17: 156\u2013186.","journal-title":"Endocr. Rev."},{"key":"BF03343713_CR3","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1111\/j.1471-0528.1996.tb09541.x","volume":"103","author":"EM Wallace","year":"1996","unstructured":"Wallace E.M., Healy D.L. Inhibins and activins: roles in clinical practice. Br. J. Obstet. Gynecol. 1996, 103: 945\u2013956.","journal-title":"Br. J. Obstet. Gynecol."},{"key":"BF03343713_CR4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1073\/pnas.85.1.247","volume":"85","author":"H Meunier","year":"1988","unstructured":"Meunier H., Rivier C., Evans R.M., Vale W. Gonadal and extragonadal expression of inhibin \u03b1, \u00dfA, \u00dfB subunit in various tissues predicts diverse functions. Proc. Natl. Acad. Sci 1988, 85: 247\u2013251.","journal-title":"Proc. Natl. Acad. Sci"},{"key":"BF03343713_CR5","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1507\/endocrj.43.375","volume":"43","author":"M Wada","year":"1996","unstructured":"Wada M., Shintani Y., Kosaka M., Sano T., Hizawa K., Saito S. Immunohistochemical localization of activin A and follistatin in human tissues. Endo. J. 1996, 43: 375\u2013385.","journal-title":"Endo. J."},{"key":"BF03343713_CR6","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/330765a0","volume":"330","author":"J Yu","year":"1987","unstructured":"Yu J., Shao L., Lemas V., Yu A.L., Vaughan J., Rivier J., et al. Importance of FSH-releasing protein and inhibin in erythrodifferentiation. Nature 1987, 330: 765\u2013767.","journal-title":"Nature"},{"key":"BF03343713_CR7","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/0006-291X(87)91528-2","volume":"142","author":"Y Eto","year":"1987","unstructured":"Eto Y., Tsuji T., Takezawa M., Takano S., Yokogawa Y., Shibai H. Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1. Biochem. Biophys. Res. Commun. 1987, 142: 1095\u20131103.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF03343713_CR8","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/344868a0","volume":"344","author":"D Shubert","year":"1990","unstructured":"Shubert D., Kimura H., LaCorbiere M., Vaughan J., Karr D., Fisher W.H. Activin is a nerve cell survival molecule. Nature 1990, 344: 868\u2013870.","journal-title":"Nature"},{"key":"BF03343713_CR9","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1210\/jcem-72-2-496","volume":"72","author":"F Petraglia","year":"1991","unstructured":"Petraglia F., Sacerdote P., Cossarizza A., Angioni S., Genazzani A.D., Franceschi C., Muscettola M., Grasso G. Inhibin and activin modulate human monocyte chemotaxis and human lymphocyte interferon-? production. J. Clin. Endocrinol. Metab. 1991, 72: 496\u2013502.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03343713_CR10","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0006-291X(88)80845-3","volume":"156","author":"Y Totsuka","year":"1988","unstructured":"Totsuka Y., Tabuchi M., Kojima I., Shibai H., Ogata E. A novel action of activin A: stimulation of insulin secretion in rat pancreatic islet. Biochem. Biophys. Res. Commun. 1988, 156: 335\u2013339.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BF03343713_CR11","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/0024-3205(93)90260-A","volume":"53","author":"EJ Verspohl","year":"1993","unstructured":"Verspohl E.J., Ammon H.P.T., Wahl M.A. Activin A: its effects on rat pancreatic islets and the mechanism of action involved. Life Sci. 1993, 53: 1069\u20131078.","journal-title":"Life Sci."},{"key":"BF03343713_CR12","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0303-7207(95)03617-G","volume":"113","author":"M Furukawa","year":"1995","unstructured":"Furukawa M., Nobusawa R., Shibata H., Eto Y., Kojima I. Initiation of insulin secretion in glucose-free medium by activin A. Mol. Cell Endocrinol. 1995, 113: 83\u201387.","journal-title":"Mol. Cell Endocrinol."},{"key":"BF03343713_CR13","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1210\/endo-125-2-586","volume":"125","author":"T Mine","year":"1989","unstructured":"Mine T., Kojima I., Oghata E. Stimulation of glucose production by activin-A in isolated rat hepatocytes. Endocrinology 1989, 125: 586\u2013591.","journal-title":"Endocrinology"},{"key":"BF03343713_CR14","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1677\/jme.0.0160249","volume":"16","author":"H Shibata","year":"1996","unstructured":"Shibata H., Kanzaki M., Takeuchi T., Miyazaki J., Kojima I. Two distinct pathways activated by activin A in glucose- responsive pancreatic beta-cell lines. J. Mol. Endocrinol. 1996, 16: 249\u2013258.","journal-title":"J. Mol. Endocrinol."},{"key":"BF03343713_CR15","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/0014-5793(93)80220-O","volume":"329","author":"H Shibata","year":"1993","unstructured":"Shibata H., Yasuda H., Sekine N., Mine T., Totsuka Y., Kojima I. Activin A increases intracellular free calcium concentrations in rat pancreatic islets. FEBS Lett. 1993, 329: 194\u2013198.","journal-title":"FEBS Lett."},{"key":"BF03343713_CR16","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1210\/endo.136.7.7789321","volume":"136","author":"H Mogami","year":"1995","unstructured":"Mogami H., Kanzaki M., Nobusawa R., Zhang Y.Q., Furukawa M., Kojima I. Modulation of adenosine triphosphate-sensitive potassium channel and voltage-dependent calcium channel by activin A in HIT-T15 cells. Endocrinology 1995, 136: 2960\u20132966.","journal-title":"Endocrinology"},{"key":"BF03343713_CR17","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0014-5793(93)80549-A","volume":"319","author":"K Ogawa","year":"1993","unstructured":"Ogawa K., Abe K., Kurusawa N., Kurohmaru M., Sugino H., Takahashi M., Hayashi Y. Expression of a, \u00dfA and \u00dfB subunits of inhibin or activin and follistatin in rat pancreatic islets. FEBS Lett. 1993, 319: 217\u2013220.","journal-title":"FEBS Lett."},{"key":"BF03343713_CR18","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1507\/endocrj.42.63","volume":"42","author":"M Furukawa","year":"1995","unstructured":"Furukawa M., Eto Y., Kojima I. Expression of immunoreactive activin A in fetal rat pancreas. Endo J. 1995, 42: 63\u201368.","journal-title":"Endo J."},{"key":"BF03343713_CR19","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1210\/endo.133.2.8344202","volume":"133","author":"H Yasuda","year":"1993","unstructured":"Yasuda H., Inoue K., Shibata H., Takeuchi T., Eto Y., Hasegawa Y., Sekine N., Totsuka Y., Mine T., Ogata E., Kojima I. Existence of activin-A in A- and D-cells of rat pancreatic islet. Endocrinology 1993, 133: 624\u2013630.","journal-title":"Endocrinology"},{"key":"BF03343713_CR20","first-page":"558","volume":"80","author":"F Petraglia","year":"1995","unstructured":"Petraglia F., De Vita D., Gallinelli A., Aguzzoli L., Genazzani A.R., Romero R., Woodruff T.K. Abnormal concentration of maternal serum activin- A in gestational diseases. J. Clin. Endocrinol. Metab. 1995, 80: 558\u2013561.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03343713_CR21","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1530\/eje.0.1350340","volume":"135","author":"A Gallinelli","year":"1996","unstructured":"Gallinelli A., Gallo R., Genazzani A.D., Matteo M.L., Caruso A., Woodruff T.K., Petraglia F. Episodic secretion of activin A in pregnant women. Eur. J. Endocrinol. 1996, 135: 340\u2013344","journal-title":"Eur. J. Endocrinol."}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03343713.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03343713\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03343713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T05:31:53Z","timestamp":1565242313000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03343713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,4]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,4]]}},"alternative-id":["BF03343713"],"URL":"https:\/\/doi.org\/10.1007\/bf03343713","relation":{},"ISSN":["0391-4097","1720-8386"],"issn-type":[{"value":"0391-4097","type":"print"},{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,4]]}}}