{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:29:19Z","timestamp":1760984959439},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2009,10,11]],"date-time":"2009-10-11T00:00:00Z","timestamp":1255219200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1007\/bf03346575","type":"journal-article","created":{"date-parts":[[2014,3,28]],"date-time":"2014-03-28T21:52:01Z","timestamp":1396043521000},"page":"156-164","source":"Crossref","is-referenced-by-count":14,"title":["Proteomic profiles in hyperandrogenic syndromes"],"prefix":"10.1007","volume":"33","author":[{"given":"S.","family":"Misiti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Stigliano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Borro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Gentile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Michienzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Cerquetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Bucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Argese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Brunetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Simmaco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Toscano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,10,11]]},"reference":[{"key":"BF03346575_CR1","first-page":"347","volume":"21","author":"R Azziz","year":"2000","unstructured":"Azziz R, Carmina E, and Sawaya ME. Idiopathic hirsutism. Endocrine Review 2000, 21: 347\u201362.","journal-title":"Endocrine Review"},{"key":"BF03346575_CR2","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0140-6736(07)61345-2","volume":"25","author":"RJ Norman","year":"2007","unstructured":"Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic ovary syndrome. Lancet 2007, 25: 685\u201397.","journal-title":"Lancet"},{"key":"BF03346575_CR3","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1056\/NEJM198507253130404","volume":"313","author":"F Kuttenn","year":"1985","unstructured":"Kuttenn F, Couillin P, Girard F, et al. Late-onset adrenal hyperplasia in hirsutism. N Engl J Med 1985, 313: 224\u201331.","journal-title":"N Engl J Med"},{"key":"BF03346575_CR4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s11154-007-9053-1","volume":"8","author":"FG Riepe","year":"2007","unstructured":"Riepe FG, Sippell WG. Recent advances in diagnosis, treatment, and outcome of congenita adrenal hyperplasia due to 21-hydroxylase deficiency. Rev Endocr Metab Disord 2007, 8: 349\u201363.","journal-title":"Rev Endocr Metab Disord"},{"key":"BF03346575_CR5","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1056\/NEJMra021561","volume":"349","author":"PW Speiser","year":"2003","unstructured":"Speiser PW, White PC. Congenital adrenal hyperplasia. N Engl J Med 2003, 349: 776\u201388.","journal-title":"N Engl J Med"},{"key":"BF03346575_CR6","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S1472-6483(10)61114-5","volume":"10","author":"E Fratantonio","year":"2005","unstructured":"Fratantonio E, Vicari E, Pafumi C, Calogero AE. Genetics of polycystic ovarian syndrome. Reprod Biomed Online 2005, 10: 713\u201320.","journal-title":"Reprod Biomed Online"},{"key":"BF03346575_CR7","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1530\/eje.0.1370670","volume":"137","author":"Y Sahin","year":"1997","unstructured":"Sahin Y, Kelestimur F. The frequency of late-onset 21-hydroxylase and 11-hydroxylase deficiency in women with polycystic ovary syndrome. Eur J Endocrinol 1997, 137: 670\u20134.","journal-title":"Eur J Endocrinol"},{"key":"BF03346575_CR8","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.pnpbp.2004.01.009","volume":"28","author":"A Gladkevich","year":"2004","unstructured":"Gladkevich A, Kauffman HF, Korf J. Lymphocytes as a neuronal probe: potential for studying psychiatric disorders. Prog Neuro-psychopharmacol Biol Psychiatry 2004, 28: 559\u201376.","journal-title":"Prog Neuro-psychopharmacol Biol Psychiatry"},{"key":"BF03346575_CR9","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/0002-9378(81)90746-8","volume":"140","author":"R Hatch","year":"1981","unstructured":"Hatch R, Rosenfield RL, Kim MH, Tredway D. Hirsutism: implications, ethiology, and management. Am J Obstet Gynecol 1981, 140: 815\u201330.","journal-title":"Am J Obstet Gynecol"},{"key":"BF03346575_CR10","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1210\/er.16.3.322","volume":"16","author":"DA Ehrmann","year":"1995","unstructured":"Ehrmann DA, Barnes RB, Rosenfield RL. Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion. Endocr Rev 1995, 16: 322\u201353.","journal-title":"Endocr Rev"},{"key":"BF03346575_CR11","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1093\/clinchem\/31.4.637","volume":"31","author":"NA Schmidt","year":"1985","unstructured":"Schmidt NA, Borburg HJ, Penders TJ, Wejcamp CW. Steroid profiling\u2014an update. Clin Chem 1985, 31: 637\u20139.","journal-title":"Clin Chem"},{"key":"BF03346575_CR12","first-page":"1635","volume":"80","author":"RC Wilson","year":"1995","unstructured":"Wilson RC, Wei JQ, Cheng KC, Mercado AB, New MI. Rapid deoxyribonucleic acid analysis by allele-specific polimerase chain reaction for detection of mutations in the steroid 21-hydroxylase gene. The Jour 1995, 80: 1635\u201340.","journal-title":"The Jour"},{"key":"BF03346575_CR13","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1021\/ac950914h","volume":"68","author":"A Shevchenko","year":"1996","unstructured":"Shevchenko A, Wilm M, Vorm O, Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 1996, 68: 850\u20138.","journal-title":"Anal Chem"},{"key":"BF03346575_CR14","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ceb.2005.11.005","volume":"18","author":"TY Huang","year":"2006","unstructured":"Huang TY, DerMardirossian C, Bokoch GM. Cofilin phosphatases and regulation of actin dynamics. Curr Opin Cell Biol 2006, 18: 26\u201331.","journal-title":"Curr Opin Cell Biol"},{"key":"BF03346575_CR15","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0070-2153(04)63005-5","volume":"63","author":"SH Zigmond","year":"2004","unstructured":"Zigmond SH. Beginning and ending an actin filament: control at the barbed end. Curr Top Dev Biol 2004, 63: 145\u201388.","journal-title":"Curr Top Dev Biol"},{"key":"BF03346575_CR16","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1042\/BST20050891","volume":"33","author":"A Hall","year":"2005","unstructured":"Hall A. Rho GTPases and the control of cell behaviour. Biochem Soc Trans 2005, 33: 891\u20135.","journal-title":"Biochem Soc Trans"},{"key":"BF03346575_CR17","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0952-7915(03)00054-2","volume":"15","author":"AV Miletic","year":"2003","unstructured":"Miletic AV, Swat M, Fujikawa K, Swat W. Cytoskeletal remodelling in lymphocyte activation. Curr Opin Immunol 2003, 15: 261\u20138.","journal-title":"Curr Opin Immunol"},{"key":"BF03346575_CR18","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1007\/PL00000910","volume":"58","author":"V Pancholi","year":"2001","unstructured":"Pancholi V. Multifunctional alpha-enolase: its role in diseases. Cell Mol Life Sci 2001, 58: 902\u201320.","journal-title":"Cell Mol Life Sci"},{"key":"BF03346575_CR19","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/j.freeradbiomed.2005.02.026","volume":"38","author":"SG Rhee","year":"2005","unstructured":"Rhee SG, Chae HZ, Kim K. Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signalling. Free Radic Biol Med 2005, 38: 1543\u201352.","journal-title":"Free Radic Biol Med"},{"key":"BF03346575_CR20","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.canlet.2005.06.007","volume":"237","author":"E Liaudet-Coopman","year":"2006","unstructured":"Liaudet-Coopman E, Beaujouin M, Derocq D, et al. Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis. Cancer Lett 2006, 237: 167\u201379.","journal-title":"Cancer Lett"},{"key":"BF03346575_CR21","doi-asserted-by":"crossref","first-page":"7207","DOI":"10.1128\/MCB.21.21.7207-7217.2001","volume":"21","author":"KC Yeung","year":"2001","unstructured":"Yeung KC, Rose DW, Dhillon AS, et al. Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAKI and inhibits NF-kappaB activation. Mol Cell Biol 2001, 21: 7207\u201317.","journal-title":"Mol Cell Biol"},{"key":"BF03346575_CR22","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ymgme.2005.09.019","volume":"87","author":"FJ Loupatty","year":"2006","unstructured":"Loupatty FJ, van der Steen A, Ijlst L, et al. Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria. Mol Genet Metab 2006, 87: 243\u20138.","journal-title":"Mol Genet Metab"},{"key":"BF03346575_CR23","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.bbapap.2004.02.017","volume":"1699","author":"B Wilkinson","year":"2004","unstructured":"Wilkinson B, Gilbert HF. Protein disulfide isomerase. Biochim Biophys Acta 2004, 1699: 35\u201344.","journal-title":"Biochim Biophys Acta"},{"key":"BF03346575_CR24","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.cbpa.2004.02.011","volume":"8","author":"AF Miller","year":"2004","unstructured":"Miller AF. Superoxide dismutase: active sites that save, but a protein that kills. Curr Opin Chem Biol 2004, 8: 162\u20138.","journal-title":"Curr Opin Chem Biol"},{"key":"BF03346575_CR25","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.clinbiochem.2005.07.008","volume":"38","author":"R Ohkawa","year":"2005","unstructured":"Ohkawa R, Hirowatari Y, Nakamura K, et al. Platelet release of beta-thromboglobulin and platelet factor 4 and serotonin in plasma samples. Clin Biochem 2005, 38: 1023\u20136.","journal-title":"Clin Biochem"},{"key":"BF03346575_CR26","doi-asserted-by":"crossref","first-page":"9615","DOI":"10.1074\/jbc.M312165200","volume":"279","author":"B Padmanabhan","year":"2004","unstructured":"Padmanabhan B, Kuzuhara T, Adachi N, Horikoshi M. The crystal structure of CCG1\/TAF(II)250-interacting factor B (CIB). J Biol Chem 2004, 279: 9615\u201324.","journal-title":"J Biol Chem"},{"key":"BF03346575_CR27","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1590\/S0100-879X2005000700003","volume":"38","author":"JG Scandalios","year":"2005","unstructured":"Scandalios JG. Oxidative stress: molecular perception and trasduction of signals triggering antioxidant gene defences. Brazilian Journal of Medical and Biological Reserce 2005, 38: 995\u20131014.","journal-title":"Brazilian Journal of Medical and Biological Reserce"},{"key":"BF03346575_CR28","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1006\/jmbi.1999.2995","volume":"291","author":"S J\u00e4ger","year":"1999","unstructured":"J\u00e4ger S, Groll M, Huber R, Wolf DH, Heinemeyer W. Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function. J Mol Biol 1999, 291: 997\u20131013.","journal-title":"J Mol Biol"},{"key":"BF03346575_CR29","doi-asserted-by":"crossref","unstructured":"Pan Z, Wang J, Yin X, et al. The function study on the interaction between Grb2 and AMPK. Mol Cell Biochem, 307: 121\u20137.","DOI":"10.1007\/s11010-007-9591-6"},{"key":"BF03346575_CR30","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/nature01514","volume":"422","author":"S Hanash","year":"2003","unstructured":"Hanash S. Disease proteomics. Nature 2003, 422: 226\u201332.","journal-title":"Nature"},{"key":"BF03346575_CR31","doi-asserted-by":"crossref","first-page":"3519","DOI":"10.1210\/endo.142.8.8322","volume":"142","author":"TS Samy","year":"2001","unstructured":"Samy TS, Kn\u00f6ferl MW, Zheng R, Schwacha MG, Bland KI, Chaudry IH. Divergent immune responses in male and female mice after trauma-hemorrhage: dimorphic alterations in T lymphocyte steroidogenic enzyme activities. Endocrine 2001, 142: 3519\u201329.","journal-title":"Endocrine"},{"key":"BF03346575_CR32","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.0105-2896.2005.00251.x","volume":"204","author":"PJ Utz","year":"2005","unstructured":"Utz PJ. Protein arrays for studyng blood cells and their secreted products. Immunol Rev 2005, 204: 264\u201382.","journal-title":"Immunol Rev"},{"key":"BF03346575_CR33","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.cbpa.2006.01.001","volume":"10","author":"DS Chen","year":"2006","unstructured":"Chen DS, Davis MM. Molecular and functional analysis using live cell microarrays. Curr Opin Chem Biol 2006, 10: 28\u201334.","journal-title":"Curr Opin Chem Biol"},{"key":"BF03346575_CR34","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1093\/humrep\/del222","volume":"21","author":"C Hughes","year":"2006","unstructured":"Hughes C, Elgasim M, Layfield R, Atiomo W. Genomic and post-genomic approaches to polycistic ovary syndrome-progress so far: Mini review. Hum Reprod 2006, 21: 2766\u201375.","journal-title":"Hum Reprod"},{"key":"BF03346575_CR35","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1074\/mcp.R200007-MCP200","volume":"1","author":"NL Anderson","year":"2002","unstructured":"Anderson NL, Anderson NG. The human plasma proteome: history, character, and diagnostic prospects. Mol Cell Proteomics 2002, 1: 845\u201367.","journal-title":"Mol Cell Proteomics"},{"key":"BF03346575_CR36","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1210\/jc.2006-2123","volume":"92","author":"JR Wood","year":"2007","unstructured":"Wood JR, Dumesic DA, Abbott DH, Strauss JF 3rd. Molecular abnormalities in oocytes from women with polycystic ovary syndrome revealed by microarray analysis. J Clin Endocrinol Metab 2007, 92: 705\u201313.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03346575_CR37","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/molehr\/gam036","volume":"13","author":"X Ma","year":"2007","unstructured":"Ma X, Fan L, Meng Y, et al. Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome. Mol Hum Reprod 2007, 13: 527\u201335.","journal-title":"Mol Hum Reprod"},{"key":"BF03346575_CR38","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.2337\/db08-0604","volume":"57","author":"G Boden","year":"2008","unstructured":"Boden G, Duan X, Homko C, et al. Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals. Diabetes 2008, 57: 2438\u201344.","journal-title":"Diabetes"},{"key":"BF03346575_CR39","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1080\/00016340902859315","volume":"88","author":"NK Kus\u00e7u","year":"2009","unstructured":"Kus\u00e7u NK, Var A. Oxidative stress but not endothelial dysfunction exists in non-obese, young group of patients with polycystic ovary syndrome. Acta Obstet Gynecol Scand 2009, 88: 612\u20137.","journal-title":"Acta Obstet Gynecol Scand"},{"key":"BF03346575_CR40","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1152\/ajprenal.00411.2006","volume":"293","author":"MT Barati","year":"2007","unstructured":"Barati MT, Merchant ML, Kain AB, Jevans AW, McLeish KR, Klein JB. Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db\/db diabetic mice. Am J Physiol Renal Physiol 2007, 293: 1157\u201365.","journal-title":"Am J Physiol Renal Physiol"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03346575.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03346575\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03346575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T00:08:00Z","timestamp":1597622880000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03346575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,11]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["BF03346575"],"URL":"https:\/\/doi.org\/10.1007\/bf03346575","relation":{},"ISSN":["0391-4097","1720-8386"],"issn-type":[{"value":"0391-4097","type":"print"},{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,11]]}}}