{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:51:32Z","timestamp":1761519092537},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1991,3,1]],"date-time":"1991-03-01T00:00:00Z","timestamp":667785600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[1991,3]]},"DOI":"10.1007\/bf03346792","type":"journal-article","created":{"date-parts":[[2014,3,28]],"date-time":"2014-03-28T22:20:23Z","timestamp":1396045223000},"page":"219-223","source":"Crossref","is-referenced-by-count":9,"title":["Tight linkage of the human c-erbA\u03b2 gene with the syndrome of generalized thyroid hormone resistance is present in multiple kindreds"],"prefix":"10.1007","volume":"14","author":[{"given":"Henry G.","family":"Fein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. D.","family":"Burman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. -Y.","family":"Djuh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Usala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. E.","family":"Bale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. D.","family":"Weintraub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. C.","family":"Smallridge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,3,27]]},"reference":[{"key":"BF03346792_CR1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1210\/jcem-27-2-279","volume":"27","author":"S Refetoff","year":"1967","unstructured":"Refetoff S., DeWind L.T., DeGroot L.J. Familial syndrome combining deafmutism, stippled epiphyses, goiter, and abnormally high PBI: possible target organ refractoriness to thyroid hormone. J. Clin. Endocrinol. Metab. 27: 279, 1967.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03346792_CR2","doi-asserted-by":"crossref","first-page":"339","DOI":"10.7326\/0003-4819-95-3-339","volume":"95","author":"BD Weintraub","year":"1981","unstructured":"Weintraub B.D., Gershengorn M.C., Kourides I.A., Fein H. Inappropriate secretion of thyroid-stimulating hormone. Ann. Intern. Med. 95: 339, 1981.","journal-title":"Ann. Intern. Med."},{"key":"BF03346792_CR3","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/BF03346968","volume":"9","author":"JA Magner","year":"1986","unstructured":"Magner J.A., Petrick P., Menezes-Ferreira M.M., Weintraub B.D. Familial generalized resistance to thyroid hormones: report of three kindreds and correlation of patterns of affected tissues with the binding of [125I] triiodothyronine to fibroblast nuclei. J. Endocrinol. Invest. 9: 459, 1986.","journal-title":"J. Endocrinol. Invest."},{"key":"BF03346792_CR4","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1172\/JCI108133","volume":"56","author":"MC Gershengorn","year":"1975","unstructured":"Gershengorn M.C., Weintraub B.D. Thyrotropin-induced hyperthyroidism caused by selective pituitary resistance to thyroid hormone: a new syndrome of \u201cinappropriate secretion of TSH\u201d. J. Clin. Invest. 56: 633, 1975.","journal-title":"J. Clin. Invest."},{"key":"BF03346792_CR5","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0002-9343(89)90298-2","volume":"86","author":"RC Smallridge","year":"1989","unstructured":"Smallridge R.C., Parker R.A., Wiggs E.A., Rajagopal K.R., Fein H.G. Thyroid hormone resistance in a large kindred: physiologic, biochemical, pharmacologic, and neuropsychologic studies. Am. J. Med. 86: 289, 1989.","journal-title":"Am. J. Med."},{"key":"BF03346792_CR6","doi-asserted-by":"crossref","first-page":"6052","DOI":"10.1016\/S0021-9258(17)40028-7","volume":"252","author":"HH Samuels","year":"1977","unstructured":"Samuels H.H., Stanley F., Shapiro L.E. Modulation of thyroid hormone nuclear receptor levels by 3,5,3\u2032-triiodo-L-thyronine in GH1 cells. J. Biol. Chem. 252: 6052, 1977.","journal-title":"J. Biol. Chem."},{"key":"BF03346792_CR7","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0009-8981(78)90204-8","volume":"83","author":"K Liewendahl","year":"1978","unstructured":"Liewendahl K., Rosengard S., Lamberg B.A. Nuclear binding of triiodothyronine and thyroxine in lymphocytes from subjects with hyperthyroidism, hypothyroidism and resistance to thyroid hormones. Clin. Chim. Acta 83: 41, 1978.","journal-title":"Clin. Chim. Acta"},{"key":"BF03346792_CR8","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1210\/jcem-55-3-502","volume":"55","author":"C Eil","year":"1982","unstructured":"Eil C., Fein H.G., Smith T.J., Furlanetto R.W., Bourgeois M., Stelling M.W., Weintraub B.D. Nuclear binding of [125I]triiodothyronine in dispersed cultured skin fibroblasts from patients with resistance to thyroid hormone. J. Clin. Endocrinol. Metab. 55: 502, 1982.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03346792_CR9","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1210\/jcem-59-6-1081","volume":"59","author":"MM Menezes-Ferreira","year":"1984","unstructured":"Menezes-Ferreira M.M., Eil C., Wortsman J., Weintraub B.D. Decreased nuclear uptake of [125I]-triiodo-L-thyronine in fibroblasts from patients with peripheral thyroid hormone resistance. J. Clin. Endocrinol. Metab. 59: 1081, 1984.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03346792_CR10","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0026-0495(87)90214-9","volume":"36","author":"KI Ichikawa","year":"1987","unstructured":"Ichikawa K.I., Hughes I.A., Horwitz A.L., DeGroot L.J. Characterization of nuclear thyroid hormone receptors of cultured skin fibroblasts from patients with resistance to thyroid hormone. Metab. Clin. Exp. 36: 392, 1987.","journal-title":"Metab. Clin. Exp."},{"key":"BF03346792_CR11","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/324635a0","volume":"324","author":"J Sap","year":"1986","unstructured":"Sap J., Munoz A., Damm K., Goldberg Y., Ghysdael J., Leutz A., Beng J., Vennstrom B. The c-erbA protein is a high-affinity receptor for thyroid hormone. Nature 324: 635, 1986.","journal-title":"Nature"},{"key":"BF03346792_CR12","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/324641a0","volume":"324","author":"C Weinberger","year":"1986","unstructured":"Weinberger C., Thompson C.C., Ong E.S., Lebo R., Gruol D.J., Evans R.M. The c-erbA gene encodes a thyroid hormone receptor. Nature 324: 641, 1986.","journal-title":"Nature"},{"key":"BF03346792_CR13","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1126\/science.3672126","volume":"238","author":"D Benbrook","year":"1987","unstructured":"Benbrook D., Pfahl M. A novel thyroid hormone receptor encoded by a cDNA clone from a human testis library. Science 238: 788, 1987.","journal-title":"Science"},{"key":"BF03346792_CR14","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/337659a0","volume":"337","author":"RJ Koenig","year":"1989","unstructured":"Koenig R.J., Lazar M.A., Hodin R.A., Brent G.A., Larsen P.R., Chin W.W., Moore D.D. Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature 337: 659, 1989.","journal-title":"Nature"},{"key":"BF03346792_CR15","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1126\/science.2539642","volume":"244","author":"RA Hodin","year":"1989","unstructured":"Hodin R.A., Lazar M.A., Wintman B.I., Darling D.S., Koenig R.J., Larsen P.R., Moore D.D., Chin W.W. Identification of a thyroid hormone receptor that is pituitary-specific. Science 244: 76, 1989.","journal-title":"Science"},{"key":"BF03346792_CR16","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1210\/mend-2-12-1217","volume":"2","author":"SJ Usala","year":"1988","unstructured":"Usala S.J., Bale A.E., Gesundheit N., Weinberger C., Lash R.W., Wondisford F.E., McBride O.W., Weintraub B.D. Tight linkage between the syndrome of generalized thyroid hormone resistance and the human c-erbA\u03b2 gene. Mol. Endocrinol. 2: 1217, 1988.","journal-title":"Mol. Endocrinol."},{"key":"BF03346792_CR17","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1172\/JCI114438","volume":"85","author":"SJ Usala","year":"1990","unstructured":"Usala S.J., Tennyson G.E., Bale A.E., Lash R.W., Gesundheit N., Wondisford F.E., Accili D., Hauser P., Weintraub B.D. A base mutation of the C-erbA\u03b2 thyroid hormone receptor in a kindred with generalized thyroid hormone resistance. J. Clin. Invest. 85: 93, 1990.","journal-title":"J. Clin. Invest."},{"key":"BF03346792_CR18","doi-asserted-by":"crossref","first-page":"8977","DOI":"10.1073\/pnas.86.22.8977","volume":"86","author":"A Sakurai","year":"1989","unstructured":"Sakurai A., Takeda K., Ain K., Ceccarelli P., Nakai A., Seino S., Bell G.I., Refetoff S., DeGroot L.J. Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor \u03b2. Proc. Natl. Acad. Sci. USA 86: 8977, 1989.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF03346792_CR19","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/0002-9343(81)90885-8","volume":"70","author":"MM Kaplan","year":"1981","unstructured":"Kaplan M.M., Swartz S.L., Larsen P.R. Partial peripheral resistance to thyroid hormone. Am. J. Med. 70: 1115, 1981.","journal-title":"Am. J. Med."}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03346792.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03346792\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03346792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T06:29:40Z","timestamp":1648708180000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03346792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1991,3]]}},"alternative-id":["BF03346792"],"URL":"https:\/\/doi.org\/10.1007\/bf03346792","relation":{},"ISSN":["0391-4097","1720-8386"],"issn-type":[{"value":"0391-4097","type":"print"},{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,3]]}}}