{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:29:26Z","timestamp":1760189366531},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1986,12,1]],"date-time":"1986-12-01T00:00:00Z","timestamp":533779200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[1986,12]]},"DOI":"10.1007\/bf03346977","type":"journal-article","created":{"date-parts":[[2014,3,27]],"date-time":"2014-03-27T17:18:20Z","timestamp":1395940700000},"page":"507-512","source":"Crossref","is-referenced-by-count":15,"title":["Insulin autoimmune syndrome with insulin-resistant diabetes at the incipient stage prior to hypoglycemic attacks"],"prefix":"10.1007","volume":"9","author":[{"given":"Akitsugu","family":"Masuda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Tsushima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Shizume","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Omori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Demura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Ohashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Odagiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,4,11]]},"reference":[{"key":"BF03346977_CR1","first-page":"312","volume":"13","author":"Y Hirata","year":"1970","unstructured":"Hirata Y., Ishizu H., Ouchi N., Motomura S., Abe M., Hara Y., Wakasugi H., Takahashi I., Sakano H., Tanaka M., Kawano H., Kanesaki T. [Insulin autoimmunity in a case of spontaneous hypoglycemia.] (Jap.) J. Jpn. Diab. Soc. 13: 312, 1970.","journal-title":"J. Jpn. Diab. Soc."},{"key":"BF03346977_CR2","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1620\/tjem.107.277","volume":"107","author":"Y Hirata","year":"1972","unstructured":"Hirata Y., Ishizu H. Elevated insulin-binding capacity of serum proteins in a case with spontaneous hypoglycemia and mild diabetes not treated with insulin. Tohoku J. Exp. Med. 107: 277, 1972.","journal-title":"Tohoku J. Exp. Med."},{"key":"BF03346977_CR3","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/BF01239429","volume":"9","author":"S Nakagawa","year":"1973","unstructured":"Nakagawa S., Suda N., Kudo M., Kawasaki M. A new type of hypoglycemia in a newborn infant. Diabetologia 9: 367, 1973.","journal-title":"Diabetologia"},{"key":"BF03346977_CR4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2337\/diab.23.1.41","volume":"23","author":"A Ohneda","year":"1974","unstructured":"Ohneda A., Matsuda K., Sato M., Yamagata S., Sato T. Hypoglycemia due to apparent autoantibodies to insulin: Characterization of insulin-binding protein. Diabetes 23: 41, 1974.","journal-title":"Diabetes"},{"key":"BF03346977_CR5","doi-asserted-by":"crossref","first-page":"214","DOI":"10.7326\/0003-4819-81-2-214","volume":"81","author":"Y Hirata","year":"1974","unstructured":"Hirata Y., Tominaga M., Ito J., Noguchi A. Spontaneous hypoglycemia with insulin autoimmunity in Graves\u2019 disease. Ann. Intern. Med. 81: 214, 1974.","journal-title":"Ann. Intern. Med."},{"key":"BF03346977_CR6","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/BF00422317","volume":"11","author":"S Kawazu","year":"1975","unstructured":"Kawazu S., Kanazawa Y., Kajinuma H., Miki E., Kuzuya T., Kosaka K. Demonstration of anti-\u201ca-component\u201d antibody: A possible means to differentiate patients with auto-antibodies to endogenous insulin from insulin-treated patients. Diabetologia 11: 169, 1975.","journal-title":"Diabetologia"},{"key":"BF03346977_CR7","doi-asserted-by":"crossref","first-page":"500","DOI":"10.2337\/diab.26.5.500","volume":"26","author":"K Ichihara","year":"1977","unstructured":"Ichihara K., Shima K., Saito Y., Nonaka K., Tarui S., Nishikawa M. Mechanism of hypoglycemia observed in a patient with insulin autoimmune syndrome. Diabetes 26: 500, 1977.","journal-title":"Diabetes"},{"key":"BF03346977_CR8","first-page":"278","volume-title":"Diabetes: Proceedings of the IX congress of the International Diabetes Federation","author":"Y Hirata","year":"1977","unstructured":"Hirata Y. Spontaneous insulin antibodies and hypoglycemia. In: Bajaj J.S. (Ed.), Diabetes: Proceedings of the IX congress of the International Diabetes Federation. Excerpta Medica, Amsterdam-Oxford, 1977, ICS413, p. 278."},{"key":"BF03346977_CR9","doi-asserted-by":"crossref","first-page":"814","DOI":"10.2337\/diab.21.7.814","volume":"21","author":"I F\u00f8lling","year":"1972","unstructured":"F\u00f8lling I., Norman N. Hyperglycemia, hypoglycemic attacks, and production of anti-insulin antibodies without previous known immunization: Immunological and functional studies in a patient. Diabetes 21: 814, 1972.","journal-title":"Diabetes"},{"key":"BF03346977_CR10","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/0002-9343(78)90530-2","volume":"64","author":"JH Anderson","year":"1978","unstructured":"Anderson J.H., Blackard W.G., Goldman J., Rubenstein A.H. Diabetes and hypoglycemia due to insulin antibodies. Am. J. Med. 64: 868, 1978.","journal-title":"Am. J. Med."},{"key":"BF03346977_CR11","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1172\/JCI109374","volume":"63","author":"J Goldman","year":"1979","unstructured":"Goldman J., Baldwin D., Rubenstein A.H., Klink D.D., Blackard W.G., Fisher L.K., Roe T.F., Schnure J.J. Characterization of circulating insulin and proinsulin-binding antibodies in autoimmune hypoglycemia. J. Clin. Invest. 63: 1050, 1979.","journal-title":"J. Clin. Invest."},{"key":"BF03346977_CR12","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0140-6736(83)91193-5","volume":"2","author":"AC Burden","year":"1983","unstructured":"Burden A.C., Rosenthal F.D. Methimazole and insulin autoimmune syndrome. Lancet 2: 1311, 1983.","journal-title":"Lancet"},{"key":"BF03346977_CR13","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1001\/archinte.1984.00350220067015","volume":"144","author":"EA Benson","year":"1984","unstructured":"Benson E.A., Ho P., Wang C., Wu P.C., Fredlund P.N., Yueng R.T.T. Insulin autoimmunity as a cause of hypoglycemia. Arch. Intern. Med. 144: 2351, 1984.","journal-title":"Arch. Intern. Med."},{"key":"BF03346977_CR14","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0140-6736(83)91031-0","volume":"2","author":"Y Hirata","year":"1983","unstructured":"Hirata Y. Methimazole and insulin autoimmune syndrome with hypoglycemia. Lancet 2: 1037, 1983.","journal-title":"Lancet"},{"key":"BF03346977_CR15","first-page":"150A","volume":"32","author":"S Takayama","year":"1983","unstructured":"Takayama S., Hirata Y. Incidence of insulin autoimmune hypoglycemia in Japan during three-year period from 1979 to 1981. Diabetes 32 (suppl.): 150A, 1983.","journal-title":"Diabetes"},{"key":"BF03346977_CR16","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1210\/jcem-61-6-1105","volume":"61","author":"O Isozaki","year":"1985","unstructured":"Isozaki O., Tsushima T., Shizume K., Saji M., Ohba Y., Emoto N., Sato K., Sato V., Kusakabe K. Thyroid-stimulating antibody bioassay using porcine thyroid cells cultured in follicles. J. Clin. Endocrinol. Metab. 61: 1105, 1985.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03346977_CR17","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1365-2265.1982.tb01607.x","volume":"17","author":"G Shewring","year":"1982","unstructured":"Shewring G., Smith B.R. An improved radioreceptor assay for TSH receptor antibodies. Clin. Endocrinol. (Oxf.) 17: 409, 1982.","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"BF03346977_CR18","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1172\/JCI104122","volume":"39","author":"GM Grodsky","year":"1960","unstructured":"Grodsky G.M., Forsham P.H. An immunochemical assay of total extractable insulin in man. J. Clin. Invest. 39: 1070, 1960.","journal-title":"J. Clin. Invest."},{"key":"BF03346977_CR19","doi-asserted-by":"crossref","first-page":"590","DOI":"10.2337\/diab.22.8.590","volume":"22","author":"S Nakagawa","year":"1973","unstructured":"Nakagawa S., Nakayama H., Sasaki T., Yoshino K., Yu Y.Y., Shinozaki K., Aoki S., Mashimo K. A simple method for the determination of serum free insulin levels in insulin-treated patients. Diabetes 22: 590, 1973.","journal-title":"Diabetes"},{"key":"BF03346977_CR20","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1172\/JCI103262","volume":"35","author":"SA Berson","year":"1956","unstructured":"Berson S.A., Yalow R.S., Bauman A., Rothschild M.A., Newerly K. Insulin-I131 metabolism in human subjects: Demonstration of insulin binding globulin in the circulation of insulin treated subjects. J. Clin. Invest. 35: 170, 1956.","journal-title":"J. Clin. Invest."},{"key":"BF03346977_CR21","first-page":"54","volume":"50","author":"M Takei","year":"1980","unstructured":"Takei M. [Insulin auto-antibodies produced by methimazole treatment in the patients with Graves\u2019 disease] (Jap.) J. Tokyo Women\u2019s Med. Coll. 50: 54, 1980.","journal-title":"J. Tokyo Women\u2019s Med. Coll."},{"key":"BF03346977_CR22","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1136\/bmj.288.6414.349","volume":"288","author":"TJ Wilkin","year":"1984","unstructured":"Wilkin T.J., Nicholson S. Autoantibodies against human insulin. Br. Med. J. 288: 349, 1984.","journal-title":"Br. Med. J."}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03346977.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03346977\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03346977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T10:43:19Z","timestamp":1558521799000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03346977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,12]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1986,12]]}},"alternative-id":["BF03346977"],"URL":"https:\/\/doi.org\/10.1007\/bf03346977","relation":{},"ISSN":["0391-4097","1720-8386"],"issn-type":[{"value":"0391-4097","type":"print"},{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,12]]}}}