{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:00:36Z","timestamp":1791896436267,"version":"4.3.4"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2003,8,1]],"date-time":"2003-08-01T00:00:00Z","timestamp":1059696000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[2003,8]]},"DOI":"10.1007\/bf03347348","type":"journal-article","created":{"date-parts":[[2014,3,31]],"date-time":"2014-03-31T08:44:00Z","timestamp":1396255440000},"page":"RC15-RC18","source":"Crossref","is-referenced-by-count":20,"title":["Presence of cortistatin in the human pancreas"],"prefix":"10.1007","volume":"26","author":[{"given":"M.","family":"Papotti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Tarabra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"All\u00eca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Bozzalla-Cassione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Broglio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Deghenghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ghigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampiero","family":"Muccioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,3,31]]},"reference":[{"key":"BF03347348_CR1","doi-asserted-by":"crossref","first-page":"5868","DOI":"10.1523\/JNEUROSCI.17-15-05868.1997","volume":"17","author":"L Lecea de","year":"1997","unstructured":"de Lecea L, del Rio JA, Criado JR, et al. Cortistatin is expressed in a distinct subset of cortical interneurons. J Neurosci 1997, 17: 5868\u201380.","journal-title":"J Neurosci"},{"key":"BF03347348_CR2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/bbrc.1997.6252","volume":"232","author":"S Fukusumi","year":"1997","unstructured":"Fukusumi S, Kitada C, Takekawa S, et al. Identification and characterization of a novel human cortistatin-like peptide. Biochem Biophys Res Commun 1997, 232: 157\u201363.","journal-title":"Biochem Biophys Res Commun"},{"key":"BF03347348_CR3","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1159\/000015566","volume":"89","author":"K Ejeskar","year":"2000","unstructured":"Ejeskar K, Abel F, Sjoberg R, Backstrom J, Kogner P, Martinsson T. Fine mapping of the human preprocortistatin gene (CORT) to neuroblastoma consensus deletion region 1p36.3_p36.2, but absence of mutations in primary tumors. Cytogenet Cell Genet 2000, 89: 62\u20136.","journal-title":"Cytogenet Cell Genet"},{"key":"BF03347348_CR4","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0165-0173(00)00031-X","volume":"33","author":"AD Spier","year":"2000","unstructured":"Spier AD, de Lecea L. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res Rev 2000, 33: 228\u201341.","journal-title":"Brain Res Rev"},{"key":"BF03347348_CR5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF03343800","volume":"24","author":"R Deghenghi","year":"2001","unstructured":"Deghenghi R, Papotti M, Ghigo E, Muccioli G. Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland. J Endocrinol Invest 2001, 24: RC1\u20133.","journal-title":"J Endocrinol Invest"},{"key":"BF03347348_CR6","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0014-2999(02)01432-2","volume":"440","author":"G Muccioli","year":"2002","unstructured":"Muccioli G, Tsch\u00f6p M, Papotti M, Deghenghi R, Heiman M, Ghigo E. Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity. Eur J Pharmacol 2002, 440: 235\u201354.","journal-title":"Eur J Pharmacol"},{"key":"BF03347348_CR7","doi-asserted-by":"crossref","first-page":"3783","DOI":"10.1210\/jcem.87.8.8749","volume":"87","author":"F Broglio","year":"2002","unstructured":"Broglio F, Arvat E, Benso A, et al. Endocrine activities of cortistatin- 14 and its interaction with GHRH and ghrelin in humans. J Clin Endocrinol Metab 2002, 87: 3783\u201390.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR8","doi-asserted-by":"crossref","first-page":"4829","DOI":"10.1210\/jc.2002-020956","volume":"87","author":"F Broglio","year":"2002","unstructured":"Broglio F, van Koetsveld P, Benso A, et al. Ghrelin secretion is inhibited by either somatostatin or cortistatin in human. J Clin Endocrinol Metab 2002, 87: 4829\u201332.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR9","doi-asserted-by":"crossref","first-page":"RC31","DOI":"10.1007\/BF03343939","volume":"24","author":"R Deghenghi","year":"2001","unstructured":"Deghenghi R, Avallone R, Torsello A, Muccioli G, Ghigo E, Locatelli V. Growth hormone-inhibiting activity of cortistatin in the rat. J Endocrinol Invest 2001, 24: RC31\u20133.","journal-title":"J Endocrinol Invest"},{"key":"BF03347348_CR10","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1210\/jc.2002-020950","volume":"88","author":"J Dalm","year":"2003","unstructured":"Dalm J, van Hagen PM, van Koetsveld PM, et al. Cortistatin rather then somatostatin as potential endogenous ligand for somatostatin receptors in the human immune system. J Clin Endocrinol Metab 2003, 88: 270\u20136.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR11","doi-asserted-by":"crossref","first-page":"5083","DOI":"10.1210\/jcem.86.10.8098","volume":"86","author":"F Broglio","year":"2001","unstructured":"Broglio F, Arvat E, Benso A, et al. Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans. J Clin Endocrinol Metab 2001, 86: 5083\u20136.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR12","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1210\/jcem.87.3.8279","volume":"87","author":"M Volante","year":"2002","unstructured":"Volante M, All\u00eca E, Gugliotta P, et al. Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors. J Clin Endocrinol Metab 2002, 87: 1300\u201308.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR13","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1046\/j.1365-2362.2003.01112.x","volume":"33","author":"O Ukkola","year":"2003","unstructured":"Ukkola O. Ghrelin and insulin metabolism. Eur J Clin Invest 2003, 33: 183\u20135.","journal-title":"Eur J Clin Invest"},{"key":"BF03347348_CR14","doi-asserted-by":"crossref","first-page":"3746","DOI":"10.1210\/jcem.83.10.5314","volume":"83","author":"JC Reubi","year":"1998","unstructured":"Reubi JC, Kappeler A, Waser B, Schonbrunn A, Laissue J. Immunohistochemical localization of somatostatin receptor sst2A in human pancreatic islets. J Clin Endocrinol Metab 1998, 83: 3746\u20139.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR15","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s00428-002-0609-x","volume":"440","author":"M Papotti","year":"2002","unstructured":"Papotti M, Bongiovanni M, Volante M, et al. Expression of somatostatin receptor types 1-5 in 81 cases of gastro-intestinal and pancreatic (GEP) endocrine tumors. A correlative immunohistochemical and RT-PCR analysis. Virchows Arch 2002, 440: 461\u201375.","journal-title":"Virchows Arch"},{"key":"BF03347348_CR16","doi-asserted-by":"crossref","first-page":"5052","DOI":"10.1210\/jcem.86.10.7918","volume":"86","author":"M Papotti","year":"2001","unstructured":"Papotti M, Cassoni P, Volante M, Deghenghi R, Muccioli G, Ghigo E. Ghrelin-producing endocrine tumors of the stomach and intestine. J Clin Endocrinol Metab 2001, 86: 5052\u20139.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR17","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0006-8993(99)02336-7","volume":"858","author":"M Sanchez-Alavez","year":"2000","unstructured":"Sanchez-Alavez M, Gomez-Chavarin M, Navarro L, et al. Cortistatin modulates memory processes in rats. Brain Res 2000, 858: 78\u201383.","journal-title":"Brain Res"},{"key":"BF03347348_CR18","first-page":"349","volume":"1","author":"L Lecea de","year":"1996","unstructured":"de Lecea L, Sutcliffe JR. Peptides, sleep and cortistatin. Mol Psychiatry 1996, 1: 349\u201351.","journal-title":"Mol Psychiatry"},{"key":"BF03347348_CR19","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/frne.1999.0183","volume":"20","author":"YC Patel","year":"1999","unstructured":"Patel YC. Somatostatin and its receptor family. Front Neuroendocrinol 1999, 20: 157\u201398.","journal-title":"Front Neuroendocrinol"},{"key":"BF03347348_CR20","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1159\/000048143","volume":"56","author":"M Kojima","year":"2001","unstructured":"Kojima M, Hosoda H, Kangawa K. Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor. Horm Res 2001, 56: 93\u20137.","journal-title":"Horm Res"},{"key":"BF03347348_CR21","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1210\/jc.2002-021161","volume":"88","author":"M Arosio","year":"2003","unstructured":"Arosio M, Ronchi CL, Gebbia C, Cappiello V, Beck-Peccoz P, Peracchi M. Stimulatory effects of ghrelin on circulating somatostatin and pancreatic polypeptide levels. J Clin Endocrinol Metab 2003, 88: 701\u20134.","journal-title":"J Clin Endocrinol Metab"},{"key":"BF03347348_CR22","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.2337\/diabetes.51.10.2911","volume":"51","author":"P Lucidi","year":"2002","unstructured":"Lucidi P, Murdolo G, Di Loreto C, et al. Ghrelin is not necessary for adequate hormonal counterregulation of insulin-induced hypoglycemia. Diabetes 2002, 51: 2911\u20134.","journal-title":"Diabetes"}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03347348.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03347348\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03347348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T22:40:01Z","timestamp":1565304001000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03347348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["BF03347348"],"URL":"https:\/\/doi.org\/10.1007\/bf03347348","relation":{},"ISSN":["0391-4097","1720-8386"],"issn-type":[{"value":"0391-4097","type":"print"},{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,8]]}}}