{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T04:42:33Z","timestamp":1782276153123,"version":"3.54.5"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1992,1,1]],"date-time":"1992-01-01T00:00:00Z","timestamp":694224000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Endocrinol Invest"],"published-print":{"date-parts":[[1992,1]]},"DOI":"10.1007\/bf03348648","type":"journal-article","created":{"date-parts":[[2014,4,4]],"date-time":"2014-04-04T10:57:59Z","timestamp":1396609079000},"page":"19-24","source":"Crossref","is-referenced-by-count":12,"title":["Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism"],"prefix":"10.1007","volume":"15","author":[{"given":"I.","family":"Miyamori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Takasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Itoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Iki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,4,4]]},"reference":[{"key":"BF03348648_CR1","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1016\/S0021-9258(18)34909-3","volume":"257","author":"MD Chue","year":"1982","unstructured":"Chue M.D., UlickS. Isolation and identification of 18-hydroxycortisol from the urine of patients with primary aldosteronism. J. Biol. Chem. 257: 2218, 1982.","journal-title":"J. Biol. Chem."},{"key":"BF03348648_CR2","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.3109\/10641968209061640","volume":"A","author":"S Ulick","year":"1982","unstructured":"Ulick S., Chue M.D. Hypersecretion of a new corticosteroid, 18-hydroxycortisol in two types of adrenocortical hypertension. Clin. Exp. Hypertens. A: 1771, 1982.","journal-title":"Clin. Exp. Hypertens"},{"key":"BF03348648_CR3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1365-2265.1988.tb01228.x","volume":"29","author":"JRE Daveis","year":"1988","unstructured":"Daveis J.R.E., Burt D., Corrie J.E.T., Edwards C.R.W., Sheppard M.C. Dexamethasone-suppressible hyperaldosteronism: studies on overproduction of 18-hydroxycortisol in three affected family members. Clin. Endocrinol. (Oxf.) 29: 297, 1988.","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"BF03348648_CR4","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1093\/clinchem\/31.6.849","volume":"37","author":"JET Corrie","year":"1985","unstructured":"Corrie J.E.T., Edwards C.R.W., Budd P.S. A radioimmunoassay for 18-hydroxycortisol in plasma and urine. Clin. Chem. 37: 849, 1985.","journal-title":"Clin. Chem."},{"key":"BF03348648_CR5","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1210\/endo-115-2-462","volume":"755","author":"EP Gomez-Sanchez","year":"1984","unstructured":"Gomez-Sanchez E.P., Gomez-Sanchez C.P., Smith J.S., Ferris M.W., Foecking M.F. Receptor binding of biological activity of 18-hydroxycortisol. Endocrinology 755: 462, 1984.","journal-title":"Endocrinology"},{"key":"BF03348648_CR6","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0022-4731(87)90176-2","volume":"27","author":"CE Gomez-Sanchez","year":"1987","unstructured":"Gomez-Sanchez C.E., Gomez-Sanchez E.P., Holland B. Role of 18-hydroxylated Cortisols in hypertension. J. Steroid Biochem. 27: 971, 1987.","journal-title":"J. Steroid Biochem."},{"key":"BF03348648_CR7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1210\/jcem-60-1-67","volume":"60","author":"DC Kern","year":"1985","unstructured":"Kern D.C., Tang K., Hanson C.S., Brown R.D., Paiton R., Weinberber M., Hollifield J.W. The prediction of anatomical morphology of primary aldosteronism using serum 18-hydroxycorticosterone levels. J. Clin. Endocrinol. Metab. 60: 67, 1985.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03348648_CR8","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1365-2265.1985.tb01118.x","volume":"23","author":"JET Corrie","year":"1985","unstructured":"Corrie J.E.T., Edwards C.R.W., Jones D.B., Padfield P.L., Budd P.S. Factors affecting the secretion of 18-hydroxycortisol, a novel steroid of relevance to conn\u2019s syndrome. Clin. Endocrinol. (Oxf.) 23: 579, 1985.","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"BF03348648_CR9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/ajh\/3.7.576","volume":"3","author":"I Irony","year":"1990","unstructured":"Irony I., Claudio E.K., Biglieri E.G., Schackleton C.H.L. Correctable subsets of primary aldosteronism. Primary adrenal hyperplasia and renin responsive adenoma. Am. J. Hypertens. 3: 576, 1990.","journal-title":"Am. J. Hypertens."},{"key":"BF03348648_CR10","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1507\/endocrj1954.34.809","volume":"34","author":"I Miyamori","year":"1987","unstructured":"Miyamori I., Yasuhara S., Matsubara T., Okamoto S., Ikeda M., Koshida H., Morise T., Takeda Y., Takeda R., Vecsei P. Effects of corticotropin-releasing factor (CRF) on aldosterone and 18-hydroxycorticosterone in essential hypertension and primary aldosteronism. Endocrinol. Jpn. 34: 809, 1987.","journal-title":"Endocrinol. Jpn."},{"key":"BF03348648_CR11","first-page":"III","volume-title":"Controversies on the adrenal hormone disorders","author":"I Miyamori","year":"1989","unstructured":"Miyamori I., Matsubara T., Takeda R. Idiopathic hyperaldosteronism. In: Takeda R., Miyamori I. (Eds.) Controversies on the adrenal hormone disorders. Elsevier, Amsterdam, 1989, p. III."},{"key":"BF03348648_CR12","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1210\/jcem-65-2-310","volume":"65","author":"CE Gomez-Sanchez","year":"1987","unstructured":"Gomez-Sanchez C.E., Upcavage R.J., Zager P.G., Foecking M.F., Holland O.B., Ganguly A. Urinary 18-hydroxycortisol and its relationship to the excretion of other adrenal steroids. J. Clin. Endocrinol. Metab. 65: 310, 1987.","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BF03348648_CR13","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/BF01931912","volume":"28","author":"P Vecsei","year":"1972","unstructured":"Vecsei P., Penke B., Joumaah A.J. Radioimmunoassay of free aldosterone and its 18- oxo-glucuronide in human urine. Experientia 28: 622, 1972.","journal-title":"Experientia"},{"issue":"Suppl5","key":"BF03348648_CR14","first-page":"S103","volume":"5","author":"RD Gordon","year":"1987","unstructured":"Gordon R.D., Gomez-Sanchez C.E., Hamlet S.M., Tunny T.J., Klemm S.A. Angiotensin-responsive aldosterone-producing adenoma masquerades as idiopathic hyperaldosteronism (IHA: adrenal hyperplasia) or low-renin essential hypertension. J. Hypertens. 5(Suppl 5): S103, 1987.","journal-title":"J. Hypertens."},{"key":"BF03348648_CR15","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/ajh\/3.7.576","volume":"3","author":"I Irony","year":"1990","unstructured":"Irony I., Kater C.E., Biglieri E.G., Shackleton C.H.L. Correctable subsets of primary aldosteronism. Primary adrenal hyperplasia and renin responsive adenoma. Am. J. Hypertens. 3: 576, 1990.","journal-title":"Am. J. Hypertens."},{"key":"BF03348648_CR16","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1177\/000456328902600303","volume":"26","author":"R Lapworth","year":"1989","unstructured":"Lapworth R., Short F., James V.H.T. 18-hydroxycorticosterone as a marker for primary hyperaldosteronism. Ann. Clin. Biochem. 26: 227, 1989.","journal-title":"Ann. Clin. Biochem."},{"key":"BF03348648_CR17","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/BF02915624","volume":"1","author":"H Sasamo","year":"1990","unstructured":"Sasamo H., Mason J.I., Sansano N., Nagura H. Immunolocalization of 3b-hydroxysteroid dehydro-genase in human adrenal cortex and its disorders. Endocr. Pathol. 1: 94, 1990.","journal-title":"Endocr. Pathol."},{"key":"BF03348648_CR18","doi-asserted-by":"crossref","unstructured":"Immunohistochemical study of cytochrome P-450 17a-hydroxylase in human adrenocortical disorders. Hum. Pathol. 20: 113, 1989.","DOI":"10.1016\/0046-8177(89)90174-3"},{"key":"BF03348648_CR19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0303-7207(91)90254-P","volume":"76","author":"A Ogo","year":"1991","unstructured":"Ogo A., Haji M., Ohashi M., Nawata H. Expression of cytochrome P-450 mRNA in steroidogenesis of adrenocortical adenomas from patients with primary aldosteronism. Mol. Cell. Endocrinol. 76: 7, 1991.","journal-title":"Mol. Cell. Endocrinol."},{"issue":"157","key":"BF03348648_CR20","volume":"129","year":"1991","unstructured":"Burt D., Creedy A.M., Bird I.M., Nicol M., Walker S.W., Edwards C.R.W., Williiams B.C. Metabolism of Cortisol by bovine zona fasciculata\/reticularis cells-Differential effects of acute stimulation on 18-hydroxylase and 11\\-hydroxysteroid dehydrogenase. J. Endocrinol. 129(Suppl 57): 1991 (Abstract).","journal-title":"J. Endocrinol."},{"key":"BF03348648_CR21","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0960-0760(91)90342-3","volume":"38","author":"H Takasaki","year":"1991","unstructured":"Takasaki H., Miyamori I., Nagai K., Takeda R., Mochizuki H., Katagiri M. Cytochrome P-450 activities in aldosteronoma tis-sues in primary aldosteronism. J. Steroid Biochem. Mol. Biol. 38: 533, 1991.","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"BF03348648_CR22","first-page":"10635","volume":"5","author":"T Ogishima","year":"1989","unstructured":"Ogishima T., Mitani F., Ishimura Y. Isolation of aldosterone synthase cytochrome P-450 from zona glomerulosa mitochondria of rat adrenal cortex. J. Biol. Chem. 5: 10635, 1989.","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Endocrinological Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03348648.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF03348648\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF03348648","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T19:50:22Z","timestamp":1648756222000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF03348648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1992,1]]}},"alternative-id":["BF03348648"],"URL":"https:\/\/doi.org\/10.1007\/bf03348648","relation":{},"ISSN":["0391-4097","1720-8386"],"issn-type":[{"value":"0391-4097","type":"print"},{"value":"1720-8386","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,1]]}}}